Tablet

21
TABLETS Presented by: Group B Sairoos, Kanchana, Sanoji, Ganga, Anushi, Dilini

Transcript of Tablet

Page 1: Tablet

TABLETS

Presented by: Group B

Sairoos, Kanchana, Sanoji, Ganga, Anushi, Dilini

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What is a Tablet

Process of Tablets Production

Tablets Excipients

Different Types of Tablets

Conclusion

Objectives

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WHAT IS A TABLET?

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Tablet is defined as a compressed solid dosage form

containing medicaments with or without excipients

with single dose of one or more active ingredients.

Tablet are usually circular shape but there are

different shapes also.

Tablet is…

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PROCESS OF TABLETS PRODUCTION

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PROCESS OF TABLETS PRODUCTION

Weighing – Active ingredients and excipients

Dry mixing -Mix with drug + fillers +

disintegrants to make a homogeneous mixture.

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Process of tablets production Cont…

Agglomeration – Powder particles are made to adhere to

form large particles called granules

Dry granulation – Do for moisture sensible

drugs

Wet granulation – Add volatile and nontoxic

liquids to make granules

Drying - If wet granulation is used

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Process of tablets production Cont.…

MillingLarge granules break into small parts

Mixing - Addition of the dry binder,

lubricant, glidant

Compaction/Tableting

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TABLET EXCIPIENTS

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TABLETS EXCIPIENTS

In preparing different dosage form (medicine), it is essential to add non therapeutic and non toxic agents call excipients.

1. Diluent

2. Binder and adhesive

3. Disintegrents

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EXCIPIENTS CONT.….

4.Lubricants

5. Coloring agents

6. Flavoring agents

7. Sweetening agents

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EXCIPIENTS CONT.….

Some of them help in compression properties to the formulation.

e.g : diluents/ filler

binders

lubricants

Physical characteristics to the tablets

e. g : disintigrants

coloring agents

flavoring and sweetening agents

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EXCIPIENTS CONT.….

Stabilizers – Help in preventing microbial spoilage as well as breakdown of active ingrediants.

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Diluents• Diluents are finely powdered, inner, solid

substances. That can be mixed with the medicaments to bring up the bulk volume of tablets. e.g. Sugar, Dextrose, Lactose

Binding agents

• Binding agents use for the conversion of finely powdered materials into granules.

e.g. Acacia, Gum tragacanth, Starch

EXCIPIENTS CONT….

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3. Granulating agents.

• Convert particles in to granules forms.

eg: Water, Alcohol

4. Disintegrating agents

• Added to a tablet formation to facilitate its breaking or disintegration when it contacts with the water in the GIT.

eg: Maize starch, Potato starch, Tartaric acid

EXCIPIENTS CONT….

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DIFFERENT TYPES OF TABLETS

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1. Compressed tablet, e.g. Paracetamol tablet

2. Multiple compressed tablet

3. Repeat action tablet

4. Delayed release tablet, e.g. Enteric coated Bisacodyl tablet

Different types of Tablets

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5. Sugar coated tablet, e.g. Multivitamin tablet

6. Film coated tablet, e.g. Metronidazole tablet

7. Chewable tablet, e.g. Antacid tablet

Different types of tablets cont.…

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8. Buccal tablet, e.g. Vitamin-c tablet

9. Sublingual tablet

10. lozenges

Different types of Tablets cont. …

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CONCLUSION

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THANK YOU !!!