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Transcript of Tablet
TABLETS
Presented by: Group B
Sairoos, Kanchana, Sanoji, Ganga, Anushi, Dilini
What is a Tablet
Process of Tablets Production
Tablets Excipients
Different Types of Tablets
Conclusion
Objectives
WHAT IS A TABLET?
Tablet is defined as a compressed solid dosage form
containing medicaments with or without excipients
with single dose of one or more active ingredients.
Tablet are usually circular shape but there are
different shapes also.
Tablet is…
PROCESS OF TABLETS PRODUCTION
PROCESS OF TABLETS PRODUCTION
Weighing – Active ingredients and excipients
Dry mixing -Mix with drug + fillers +
disintegrants to make a homogeneous mixture.
Process of tablets production Cont…
Agglomeration – Powder particles are made to adhere to
form large particles called granules
Dry granulation – Do for moisture sensible
drugs
Wet granulation – Add volatile and nontoxic
liquids to make granules
Drying - If wet granulation is used
Process of tablets production Cont.…
MillingLarge granules break into small parts
Mixing - Addition of the dry binder,
lubricant, glidant
Compaction/Tableting
TABLET EXCIPIENTS
TABLETS EXCIPIENTS
In preparing different dosage form (medicine), it is essential to add non therapeutic and non toxic agents call excipients.
1. Diluent
2. Binder and adhesive
3. Disintegrents
EXCIPIENTS CONT.….
4.Lubricants
5. Coloring agents
6. Flavoring agents
7. Sweetening agents
EXCIPIENTS CONT.….
Some of them help in compression properties to the formulation.
e.g : diluents/ filler
binders
lubricants
Physical characteristics to the tablets
e. g : disintigrants
coloring agents
flavoring and sweetening agents
EXCIPIENTS CONT.….
Stabilizers – Help in preventing microbial spoilage as well as breakdown of active ingrediants.
Diluents• Diluents are finely powdered, inner, solid
substances. That can be mixed with the medicaments to bring up the bulk volume of tablets. e.g. Sugar, Dextrose, Lactose
Binding agents
• Binding agents use for the conversion of finely powdered materials into granules.
e.g. Acacia, Gum tragacanth, Starch
EXCIPIENTS CONT….
3. Granulating agents.
• Convert particles in to granules forms.
eg: Water, Alcohol
4. Disintegrating agents
• Added to a tablet formation to facilitate its breaking or disintegration when it contacts with the water in the GIT.
eg: Maize starch, Potato starch, Tartaric acid
EXCIPIENTS CONT….
DIFFERENT TYPES OF TABLETS
1. Compressed tablet, e.g. Paracetamol tablet
2. Multiple compressed tablet
3. Repeat action tablet
4. Delayed release tablet, e.g. Enteric coated Bisacodyl tablet
Different types of Tablets
5. Sugar coated tablet, e.g. Multivitamin tablet
6. Film coated tablet, e.g. Metronidazole tablet
7. Chewable tablet, e.g. Antacid tablet
Different types of tablets cont.…
8. Buccal tablet, e.g. Vitamin-c tablet
9. Sublingual tablet
10. lozenges
Different types of Tablets cont. …
CONCLUSION
THANK YOU !!!