Synthetic Biology
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Transcript of Synthetic Biology
SyntheticBiologyReportElkington
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2009-2015:InvestmentsinSyntheticBiologyCompanies
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2009-2015:NumberofSyntheticBiologyCompaniesFunded
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2015:InvestmentsinSyntheticBiologyCompanies
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Currentcurrentchallengesinsyntheticbiology
• Biologyisnoisy• Thecellisacomplexandnon-deterministicmachine• Engineeringliferequirescontrolsofmanydynamicparameters
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Thelayersneededtoengineerbiologysuccessfully
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Example:StandardofInteroperabilityforSyntheticBiology
• Thegrowthofsyntheticbiologydependsonstandards.• Standardswillallownon-expertstointerfacewithbiology
Source:DrewEndy,RegistryofStandardBiological Parts 7
What’sdrivingadvancesinsyntheticbiology
8Source:RobCarlson
Who’sfundingtheseadvances
TotalSyntheticBiologyFundingin2015
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Howtheseadvancesallowcontrolofthecell
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1. Genomics(DNA/RNA)2. Proteomics3. ‘Omics (measuringother
moleculesincells)
Thefirstexampleofsyntheticbiology
11Source:Elowitz Lab
Cas9hasbeenthenextmajorstepinsyntheticbiology
12Source:Nature
DIYBio
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DIYBio andbiohackingisadevelopingmarketofindividualsthatwillhaveamajorimpactonlifesciences
Source:DIYBio.org
Conclusions
1. Investmentsinsyntheticbiologyhavebeenincreasingoverthelast6years
2. Growthinsyntheticbiologywillrelyondevelopmentofinfrastructureandstandardstoexpandthenumberofpeoplewhocanworkwithbiology
3. Fundingandfundamentaladvancesaresupportingacceleratedgrowthinthesyntheticbiologymarket
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