Synthesis β-Aminophosphonates

Speaker : Xuerui WangAdvisor： Jun Zhu

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outline• 1.Background• 2.Results and discussion• 3.The future plan

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Background

Organophosphorus compounds

pesticide flame retardant medicineAt present there are more than 100 kinds of organophosphorus pesticide in the world.

Phosphorus flame retardant sales account for more than half of the total sales of flame retardants

antibacterial agents

enzyme inhibitors

anti HIV agents

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Background :Synthesis β-Aminophosphonates

No free radical reaction

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Background

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Results and discussion

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Results and discussion

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Future plan

To optimize the reaction conditions in order to improve the yield

• 1. use other free radical initiator ( for example :AgNO3)

• 2. use other ketone and amine • 3. use other acid catalyst

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Thank you!

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