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hazards on the biochemistry and materiafs heaval1s of.C. Psyehonotor:

1 - use certain basic principles to analyze commonly;:::;il?.:i"::1,:::i::: problems in terms of rheii2 - perform basic chemical tests of the differentbiomolecules and their precursor unlts or buildingblocks;3- Trace the different metaboric pathways and computefor the the bioenerg.etics behind catibolism of themolecule.I. COT'RSE OIITLINE:ITOLECUTAR A}.IATO}Nr1 IntrcductionBiochemistry as a ,Discipline and rnterdisciplinaryScienceReview of Rerated Topics from prerequisite subjectsorganelles of the ce11 anci their Biomorecules

2 Structure and Functions of proteins'Amino Aclds: Classes and Structures.Acid-Base properties of Amino Acids .Reacti ons of the Amino, Carboxyl and R_ GroupsPeptide Bond and peptide SynthesisLevels of organization of protein l4olecutesClassification of proteinsDenaturation of protei_ns

3 Structure and Functions of CarbohvdratesClassificationSimple Sugars: Structures and propertiesTypical CarbohydratesGlycoproteinsProteoglycansUnavai lable Carbohvdrates4 Structure and Functions of Lipids

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Thre RNA MoleculeGenetic CodeProtein SynthesisReactions of Pyrimidines and PurinesEnvironmental HazardsMutations, Mutagerrs and Repair MechanismsCarcinogens and Carcinogenic l4utagens6 EnzymesChemical NatureClassifi-cation and Nomenclature

Typical EnzymesEnzyme ActivityFactors Affecting Enzyme ActivityClinical Slgnificance of Enzymesf Vitamlns and HormonesChemlcal Nature

Sources or Sites of FormationAdsorption and FunctionsDiseases caused by Over/Under supply of Vitafiins andHyper/hyposecretion of hormonesCorrelation with Other Biomol-eculesMOTECUI,AR PgYSIOTOGYB Biochemistry of Body ActivitlesDigestionAbsorptionRespirationMetabolism of Proteirrs, Carbohydrates, Lipi-ds andNuclelc Aci-ds9 Biochemistry of U::ineKidney Function: prccesses Involved in Urj-ne FormationPhysical Properties of UrineComposition of Uri-neClinical Implications from Urine Arralysis10 Biochemistry of BloodFunctions of Blood

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Chen 4LI,ABORATORY ACTIVITIES

1 pH and Buffers2 Osmotic Behavi-or of Red Blood CellsJ DIA-LVS1S4 General Characteristics of Proteins5 Color Tests for Proteins and Specific Amino Acids6 Chromatography of Amino Acids7 Denaturation of ProteinsB Identification of Unknown Amino Acid5 General Characteristics of Carbohydrates10 Tests for Carbohydrates11 Formation of Osazonesn Polysaccharides13 PolarimetryI4 identification of an Unknown CarbohvdrateI 5 Properties of Lipids16 Saponification of Fats71 Cholesterol1B Prenaraf i on and Proner:ties of Nucleic Acids!vtJvl79 Inorgianic Elements in Biological Materials20 Enzymes27 Factors Influencing Enzyme Action22 Sal-iva23 Ptyalin24 Gastric Analysis25 Feces26 Normal Constituents cf Urine21 Pathological Constituents of Urine2B Tests for Blood29 Inorganic Elements in Blood30 PlasmaVII . COTIRSE REQUIRB.{E}IIS : Prelims, mi-dterms and final examinationsQui z zesLaboratory ReportsJournal Reports on Clinical Aspects ofBiochemistryVIII COIJRSE STRATEGIES: LecturesLaboratory experimenlat j-onRole Playing

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IX. COURSE TEXTBOOK:Sylianco, Clara. Modern Bi.ochremistrv. Caloocan City:Philippine Graphic Arts, 1981.X. REFERENCES:Baum, stuart. rntroduction to orqanic and Bj_olosicaIChemistrv. New Ycrk: MacMill_an, 1987.campbell, Peter N. and Anthony D. smith. BiochemistrvIllustsated. London: Harcourt Publishers Limited, 2000.Chen, Philip. Chemistrv: Inorqanic, Oroanic and Bioloqical.Second Edition. New York: Barnes and Noble, 19j9.Lehninger, Albert. Biochemistrv. Znd Edition. New york:Worth Publishers Inc., 1975.I'4atthews, christopher K. And K.E. Van Holde. Biochemistrv.US: Benjamin/Cummings publishing Co., fnc., 1996.Montgomery, Rex . Bi.ochemistrv. Fif th edition. Missouri :C.U. Mosby Co., 1990Smith, Emil. Principles of Biochemistrv. New York: Wileyand Sons, 1918.Stephenson, William. Concepts in Biochemistrv. New York:Wiley arrd Sons, 1918.White, Abraham. Principles in Biochemistrv. New York:McGraw Hill Co., 1978.Wi-lbraham, Anthony. Introduction to Organic and BioloqicalChemistrv. USA: Cumminqs Publication, 1984.