SUSAN A. BLOOMFIELD Professor, Health and Kinesiology

College of Education and Human Development, Texas A&M University College Station, Texas 77843-4243 (979) 862-1181; sbloom@tamu.edu

PROFESSIONAL INTERESTS

Integrative physiology of bone: Exercise, disuse, microgravity effects on skeletal integrity Energy restriction effects on bone health Type 2 diabetes and bone quality Clinical exercise physiology

EDUCATION

B.A. Biology, Oberlin College, 1974 M.A. Physical Education, The University of Iowa, 1978 Ph.D. Exercise Physiology, The Ohio State University, 1992

PROFESSIONAL LICENSES

Exercise Program Director, American College of Sports Medicine Advanced Physical Fitness Specialist, Young Men's Christian Association

PROFESSIONAL EXPERIENCE Professor, Health and Kinesiology, Texas A&M University (2006 - present) Research and Grants Coordinator (2008- present) Associate Lead, National Space Biomedical Research Institute Musculoskeletal Alterations Team (2008-present); Associate Lead, NSBRI Bone Loss Team (2000-2007) Associate Professor, Health and Kinesiology, Texas A&M University (1999 - 2006)

Member, Intercollegiate Graduate Faculty of Nutrition, Texas A&M University (1999 – present) Assistant Professor, Health and Kinesiology, Texas A&M University (1993 - 1999) Visiting Assistant Professor, Exercise Science, The University of Iowa (1992 - 1993) Graduate Research Associate, Physical Medicine, The Ohio State University (1989-1991) Graduate Research Associate, Exercise Physiology, School of HPER, The Ohio State

University (1985-1989) Assistant Professor, Exercise and Health Science; Director, Adult Fitness Program; Head Coach, Women's Swimming and Diving, Alma College (MI) (1982-1985) Program Coordinator, Cardiac Rehabilitation Unit and Employee Fitness Program;

Research Assistant, Preventive Medicine, Washington University School of Medicine (1978-1982)

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Graduate Research/Teaching Associate and Assistant Coach, Women's Swimming, Physical Education, The University of Iowa (1975-1978)

TEACHING EXPERIENCE Alma College (Michigan)

Human Physiology Research Topics in Exercise Physiology* Exercise Testing and Prescription* Substance Use and Abuse* Nutrition* Biomechanics* Physiology of Exercise Rehabilitative and Therapeutic Exercise*

*Courses new to Exercise Science and Health Management curriculum, developed by SB

The University of Iowa Exercise Physiology Advanced Exercise Physiology (graduate, team taught)

Texas A&M University

Physiology of Exercise Exercise Evaluation and Prescription Seminar: Bone Biology—Impact of Exercise and Nutrition (graduate) Seminar: Endocrine Adaptations to Exercise (graduate) Fundamentals in Space Life Sciences (team taught) Exercise for Clinical Populations (graduate)

RESEARCH STUDENTS MENTORED (Awards Received, First/Current Position Post-Graduation ) Graduation ) Elizabeth Dresser, M.S. in Kinesiology, 1994 (+ABD in Nutrition, 1998): Sales representative, Merck Pharmaceuticals, San Antonio, TX. Cynthia Inman, M.S. in Kinesiology, 1996: Awards: 1st place, M.S.-level Research Poster,

TX Chapter—American College of Sports Medicine, 1996; Texas A&M Distinguished Research Thesis Award, 1996. Currently: Clinical Study Coordinator for NIH-funded projects at Washington University School of Medicine, St. Louis, MO.

Xiao-hua (Lisa) Wu, M.S. in Kinesiology, 1997: Currently: Clinical Research Coordinator at Baylor College of Medicine GCRC, Houston, TX Monica Hubal, M.S. in Kinesiology, 1999: Awards: TX Chapter—American College of Sports

Medicine, 1st place M.S. poster 2000; Texas A&M Distinguished Research Thesis Award, 2000. Currently: Post-doctoral Fellow (physiological genomics) with Dr. E. Hoffman, George Washington School of Medicine & Health Sciences, Washington D.C.

Amanda Cochran, Allied Health Summer Intern Fellow, 2000: [current position unknown] Alicia Currado Barlow, M.S., R.D. in Nutrition, 2001: Currently: Sales representative, Nestle’s Corporation. Matthew Allen, Ph.D. in Kinesiology, 2003: Awards: TX Chapter— American College of

Sports Medicine 3rd place Ph.D. poster, 2000; TX Chapter— American College of Sports Medicine 2nd place Research Manuscript Award, 2001; Alice L. Jee Memorial Young Investigator Award, 31st International Sun Valley Workshop on Skeletal Tissue Biology, 2001; TX Chapter— American College of Sports Medicine 1st place, Ph.D. poster, 2002; NIH NRSA Post-Doctoral Fellowship, 2003. Currently: Asst. Professor, Dept of Anatomy/Cell Biology, University of Indiana School of Medicine, Indianapolis.

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Anna Rockman, B.S. in Kinesiology, 2003: Awards: TX Chapter—American College of Sports Medicine 1st place Undergraduate Poster.

Amira Gerges, M.S. R.D. in Nutrition, 2004: Currently: Clinical dietician, M.D. Anderson Cancer Center, Houston, TX.

Jacky Lee, B.S in Information Management, 2006: Honors Thesis Fellow, 2004-2005. Applying to medical school. Brent Vyvial, M.S. in Mechanical Engineering, 2006 (co-chair): Engineer with Stress Engineering Systems, Houston, TX.

Justin Alcorn, M.S. in Mechanical Engineering, 2006 (co-chair): Awards: Houston Society for Engineering in Medicine and Biology Louis C. Sheppard Award for Best Poster, 2006. Currently: applying to medical school.

Sabrina Macmanus, B.S. in Theatre, 2006: Awards: TX Chapter—American College of Sports Medicine 2nd place Undergraduate Poster. Currently: Enrolled in Graduate MS program at A&M in Sports Physiology.

Lindsey Sumner, M.S. in Mechanical Engineering, 2007 (co-chair). Currently: Product Engineer, OriGen Biomedical, Austin, TX.

Jay Jeffery, M.S. in Mechanical Engineering, 2007 (co-chair) Currently: Development Engineer with Fiberspar LinePipe LLC, Houston, TX.

Kyunghwa Baek, Ph.D. in Nutrition, 2007: Awards: TX Chapter—American College of Sports Medicine 1st place M.S. poster 2003; NIH Scholar Travel Award, Vitamin D and Health in the 21st. Century: Bone and Beyond 2003; Young Investigator Travel Award, Endocrinology & Metabolism Section, Amer. Physiology Society, 2004; Alice L. Jee Memorial Young Investigator Award, 35th International Sun Valley Workshop on Skeletal Tissue, 2005; Plenary Poster at 27th American Society of Bone and Mineral Research Meeting, 2005; Annual Research Symposium Scholarship, Texas A&M Intercollegiate Faculty of Nutrition; Oral Presentation at 29th American Society of Bone and Mineral Research Meeting, 2007; Texas A&M University Distinguished Graduate Research Award, 2008. Currently: Post-doctoral Fellow, Univ. of Pennsylvania College of Veterinary Medicine (Mentor: K. Hankenson).

Samantha Manning, B.S. in Biomedical Sciences, 2009; Awards: TX Chapter—American College of Sports Medicine 1st place Undergraduate Poster.

Matt Lucas, M.S. in Mechanical Engineering, 2008 (co-chair): Engineer with Scott Bouse, M.S. in Mechanical Engineering, 2009 (co-chair): Engineer with Stress Engineering Systems, Houston, TX. Joshua Swift, B.S. Pennsylvania State University: Current Ph.D. student, 5th year. Awards:

TX Chapter—American College of Sports Medicine 2nd place M.S. poster 2005, 1st place, M.S. poster, 2006, and Student Research Development Grant 2007; Texas A&M Student Research Week, 2nd place, Oral Presentation in Life Sciences, Graduate Category, 2005; Alice L. Jee Memorial Young Investigator Award, 36th International Sun Valley Workshop on Skeletal Tissue Biology, 2006; National Space Biomedical Research Institute Pre-Doctoral Fellowship, 2006-2008; JL Huffines Institute for Sports Medicine and Human Performance Student Research Grant, 2007; Plenary poster at 29th American Society of Bone and Mineral Research Meeting, 2007; US Navy Health Services Collegiate Program Scholarship, 2007-2009; TX Chapter— American College of Sports Medicine 1st place Research Manuscript Award, 2009; Oral Presentation at 31st American Society of Bone and Mineral Research Meeting, 2009.

Mats Nilsson, M.S. Univ. Texas-El Paso: Ph.D. student 2004-07 (switched to J. Fluckey

4HLKN lab Jan 2008). Awards: TX Chapter-- American College of Sports Medicine 1st place Ph.D. poster 2006 and 2007; Texas A&M Student Research Week, 2nd place, Oral Presentation in Life Sciences, Graduate Category, 2006; Alice L. Jee Memorial Young Investigator Award, 36th International Sun Valley Workshop on Skeletal Tissue Biology, 2006.

Sibyl Swift, M.S. Kinesiology, Texas A&M Univ.: Current (Nutrition) Ph.D. student, 4th year. Awards: College of Education & Human Development Nominee for PEO Scholar Award, 2007; Alice L. Jee Memorial Young Investigator Award, 38th International Sun Valley Workshop on Skeletal Tissue Biology, 2008; Intercollegiate Faculty of Nutrition Scholarships (Summer, Fall 2008); TX Chapter— American College of Sports Medicine 4th place Research Manuscript Award and Student Research Development Grant, 2009; American Society of Nutrition Proctor & Gamble Student Research Award, 2009.

Sarah Luna: Undergraduate Honors Thesis Student, 2009-10

PROFESSIONAL ASSOCIATIONS American College of Sports Medicine (member since 1982)

Member, Program Committee; 2003- 2006 Member, Board of Trustees; 2000-2003 Research Review Committee; 2000-2003 Ethics and Professional Conduct Committee; 2003-2005 Chair, ACSM Bone and Osteoporosis Network Interest Group; 1996-1998 Symposium chair at annual meeting; 1995, 1997, 1999, 2001-2005, 2007 Member, Program Committee, 2010 Integrative Physiology of Exercise Meeting

Texas Regional Chapter, American College of Sports Medicine Board member, Texas Regional Chapter of ACSM; 1996-2001 President, 1999-2000

American Society for Bone and Mineral Research (member since 1990) American Physiological Society (member since 1996); Councillour, Environmental & Exercise Physiology Section, 2009- International Bone and Mineral Society American Association of University Women

HONORS AND AWARDS Texas Regional Chapter, Amer. College of Sports Medicine Spring Tour Lecturer (2008) Texas A&M College of Education & Human Development nominee for Association of Former Students Distinguished Research Award (2007) Texas Regional Chapter ACSM Honor Award (2004)

Texas A&M University Montague Center for Teaching Excellence Scholar (1998) Fellow, American College of Sports Medicine (1997) American Physiological Society Research Career Enhancement Award (1997) Funded working visit to laboratory of Russell T. Turner, Mayo Clinic, to learn methods

for quantifying gene expression in bone Texas A&M College of Education Outstanding New Faculty Member Award (1994) ACSM Visiting Scholar Award (1993) Funded working visit to laboratory of Don B. Kimmel, Creighton University, to learn cancellous bone histomorphometry forin vivo bone research

EDITORIAL BOARDS/REVIEWING ACTIVITIES Member, NASA Bone Expert Advisory Panel, JSC Exercise Countermeasures Project (2007-

5) Member, NASA/ESA International Multidisciplinary Artificial Gravity Project Review Panel (2005- 2007)

Member, NASA/ESA Flywheel Exercise Device Non-Advocate Review Committee (2004- 2006) Grant Reviewer (ad hoc), Department of Defense Bone Health and Military Medical

Readiness Research Program (February, 2003) NSBRI Representative, Bioastronautics Critical Path Control Panel (2000-2003) ACSM Research Foundation Reviewer (2000-2003) Grant Reviewer (ad hoc), Arkansas Science & Technology Authority (April, 2000) Grant Reviewer (ad hoc), Special Emphasis Review Panel, Geriatric and Rehabilitative

Medicine, NIH (March, 1998; June, 2001) Member, NASA Interim Resistance Exercise Device Non-Advocate Review Committee

(1998-2002) Reviewer (ad hoc), proposals to Spinal Cord Research Foundation (Paralyzed Veterans of

America) (1995-1996) Editorial Board, Medicine and Science in Sports and Exercise (2005- ) Orthopedics Section Editor, Clinical Exercise Physiology (1998-2002) Reviewer, Journal of Applied Physiology, Journal of Bone and Mineral Research International Journal of Sports Nutrition & Exercise Metabolism, Exercise and Sport

Sciences Reviews, Bone, Medicine and Science in Sports and Exercise Invited reviewer, Mayfield Publishing for Fitness and Sports Medicine: A Health-Related

Approach (4th edition), by David C. Nieman (1997) Invited reviewer, American College of Sports Medicine’s Resource Manual for Guidelines For Exercise Testing and Prescription (3rd and 4th editions) (1996 & 1999)

SERVICE Department Applied Exercise Physiology Curriculum Committee (1993- ) Teaching Practicum for Ph.D. Students Ad-Hoc Committee (1996) Honors Program Committee (1998-99) KINE 601 Ad-Hoc Committee (2000) A-1 Research Committee (2000, 2005, 2006) Faculty Travel Funds Committee (2002)

HLKN Graduate Women Scholars Network (organizer) (2006- ) KINE RB Armstrong Graduate ScholarAward Ad-Hoc Committee, Chair (2007- ) Finance & Administration Committee, Tenure-Track Faculty Representative (2007-2008) Search Committees: Exercise Physiology (1995, 2000, 2003-06; 2005-2006, Chair), Sports Physiology (1998-99), Motor Behavior (1994, 2001-02), Huffines Institute Director (2008-09)

Intercollegiate Faculty of Nutrition

Texas Human Nutrition Conference Organizing Committee (2003-2005) Executive Committee (2005-2008) Nutrition and Food Science Super Search Committee (for 5 faculty) (2006) College Faculty Evaluation Sub-Committee (2000) SAFE Task Force (2003-2004)

6 Developmental Leave Reviewer (2003) Council of Principal Investigators (2004 - ); Chair (2006- 2007) University Search Committee, Comparative Medicine Program Director –Chair (2009- ) Committee on Academic Freedom, Responsibility, and Tenure (2005 - 2007) CAFRT Preliminary Screening Committee (2007- ) Council of Principal Investigators, College of Education and Human Development Representative (2005- ); CPI Executive Committee (2008- ) Women’s Faculty Network Mentor (2004-present) Student Research Week Presentation Judge (2003) Allies Member (1996 - ) PUBLICATIONS (Co-authors who are my graduate student advisees are noted in italics) Book Chapters Smith, S.S., C.-H. E. Wang. and S.A. Bloomfield. (2009) Osteoporosis. In: J. L. Durstine,

G.E. Moore, P.L. Painter, and S.O. Roberts (Eds.). American College of Sports Medicine’s Exercise Management for Persons with Chronic Diseases and Disabilities, 3rd edition. pp. 270-279. Champaign, IL: Human Kinetics.

Bloomfield, S.A. (2007) The risks to bone health during missions to the Moon and Mars. In: P.R. Cavanagh and A.J. Rice (eds). Bone Loss During Spaceflight: Etiology, Countermeasures, and Implications for Bone Health on Earth. Pp. 229-237. Cleveland, OH: Cleveland Clinic Foundation Press.

Bloomfield, S.A. and S.S. Smith. (2003). Osteoporosis. In: J. L. Durstine and G.E. Moore (Eds.). American College of Sports Medicine’s Exercise Management for Persons with Chronic Diseases and Disabilities, 2nd edition. pp. 222-229. Champaign, IL: Human Kinetics.

Warner, S.A. and S.A. Bloomfield. (2001). Deconditioning and Best Rest: Induced Effects on Bone Health. In: J.L. Roitman (Ed.). American College of Sports Medicine Resource Manual for Guidelines for Exercise Testing and Prescription, 4th edition. Baltimore: Lippincott, Williams and Wilkins, pp. 198-202.

Bloomfield, S.A. (1998). Effects of detraining and bed rest on bone health. In: J.L. Roitman (Ed.). American College of Sports Medicine Resource Manual for Guidelines for Exercise Testing and Prescription, 3rd edition. Baltimore: Williams and Wilkins,

pp. 195-199. Bloomfield, S.A. (1997). Osteoporosis. In: J. L. Durstine (Ed.). American College of Sports

Medicine’s Exercise Management for Persons with Chronic Diseases and Disabilities. pp. 161-166. Champaign, IL: Human Kinetics.

Bloomfield, S.A. (1995). Bone, ligament, and tendon. In: D.R. Lamb, C.V. Gisolfi, and E. Nadel (Eds.). Perspectives in Exercise Science and Sports Medicine, Vol. 8: Exercise in Older Adults. pp. 175-235. Carmel, IN: Cooper Publishing Group.

Bloomfield, S.A. and E.F. Coyle. (1993). Physiological consequences of bedrest and deconditioning. In: J. L. Durstine (Ed.) American College of Sports Medicine Resource Manual for Guidelines for Exercise Testing and Prescription, 2nd edition. pp. 115-128. Philadelphia: Lea and Febiger.

Peer-Reviewed Journal Papers Swift, J.M., H.A. Hogan, M.I. Nilsson, L.R. Sumner, and S.A. Bloomfield. Simulated

resistance training during hindlimb unloading abolishes disuse bone loss and maintains muscle strength. J. Bone Miner. Res (in press)

7 Baek, K. and S. Bloomfield. (2008). Beta-adrenergic blockade and leptin replacement

effectively mitigate disuse bone loss. J. Bone Miner. Res 24: 792-799. First published online 29 Dec 2008: 10.1359/jbmr.081241.

Prisby, R.D., J.M. Swift, S.A. Bloomfield, H.A. Hogan, and M.D. Delp (2008) Alterations in bone mass, geometry and mechanical properties in the fatty Zucker rat model for Type II diabetes. J. Endocrinology 199:379-388.

Baek, K., A.A. Barlow, M.R. Allen, and S.A. Bloomfield (2008). Food restriction and simulated microgravity: effects on bone and serum leptin. J. Appl. Physiol. 104: 1086-1093. First published online February 14, 2008: doi:10.1152/japplphysiol.01209.2007.

Wallace, J.M., R.M. Rajachar, M.R. Allen, S.A. Bloomfield, P.G. Robey, M.F. Young, and D.H. Kohn. (2007). Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific. Bone 40: 1120-1127.

Kim, W-.K., L.M. Donalson, S.A. Bloomfield, H.A. Hogan, L.F. Kubena, D.J. Nisbet, and S.C. Ricke. (2007). Molt performance and bone density of cortical, medullary, and cancellous bone is laying hens during feed restriction or alfalfa-based feed molt. Poultry Sci. 86:1821-1830.

Allen, M.R., H.A. Hogan, S.A. Bloomfield. (2006). Differential bone and muscle recovery following hindlimb unloading in skeletally mature rats. J. Musculoskel. Neuron. Interact. 6: 217-225.

Wallace, J.M., R.M. Rajachar, X.-D. Chen, S. Shi, M.R. Allen, S.A. Bloomfield, C.M. Les, P.G. Robey, M.F. Young, and D.H. Kohn. (2006). The phenotype of biglycan-deficient mice is bone- and gender-specific. Bone 39: 106-116.

Hubal, M.J., C.P. Ingalls, M.R. Allen, J.C. Wenke, H.A. Hogan, and S.A. Bloomfield. (2005). Effects of eccentric exercise training on cortical bone and muscle strength in the estrogen deficient mouse. J. Appl. Physiol. 98: 1674-1681.

Bloomfield, S.A. (2005). Contributions of physical activity to bone health over the lifespan. Top. Geriatric Rehab. 21: 68-76.

Kohrt, W.M., S.A. Bloomfield, K.D. Little, M.E. Nelson, V.R. Yingling. (2004). ACSM Position Stand: Physical Activity and Bone Health. Med. Sci. Sports Exerc. 36:1985-

1996. Warren, G.L., J.L. Stallone, M.R. Allen, and S.A. Bloomfield. (2004). Functional recovery of

the plantarflexor muscle group after hindlimb unloading in the rat. Eur. J. Appl. Physiol. 93: 130-138.

Yao, Z, M-H Lafage-Proust, J. Plouet, S. Bloomfield, C. Alexandre and L. Vico. (2004) Increase of both angiogenesis and bone mass in response to exercise depends on

VEGF. J. Bone Miner. Res. 19: 1471-1480.

Narayanan, R., M.R. Allen, D. Gaddy, S.A. Bloomfield, C.L. Smith, and N. L. Weigel. (2004). Differential skeletal responses of hindlimb unloaded rats on a Vitamin D deficient diet to 1,25-dihydroxyvitamin D and its analog, Seocalcitol (EB1089). Bone 35: 134-143.

Nielsen, K.L., M.R. Allen, S.A. Bloomfield, T.L. Andersen, X.-D. Chen, T. Xu, H.S. Poulsen, M.F. Young, and A.M. Heegaard. (2003). Biglycan deficiency interferes with ovariectomy-induced bone loss. J. Bone Miner. Res. 18:2152-2158.

Chen, X.-D., M.R. Allen, S. Bloomfield, T. Xu, and M. Young. (2003). Biglycan deficient mice have delayed osteogenesis after marrow ablation. Calcif. Tiss. Int. 72: 577-582. Mekraldi, S., M.-H. Lafage-Proust, S. Bloomfield, C. Alexandre and L. Vico. (2003).

Changes in vasoactive factors associated with altered vessel morphology in the tibial metaphysic during ovariectomy-induced bone loss in rats. Bone 32: 630-641.

8Allen, M.R. and S.A. Bloomfield. (2003). Hindlimb unloading has a greater effect on

cortical compared to cancellous bone in mature female rats. J. Appl. Physiol. 94: 642-650.

Bloomfield, S.A., M.R. Allen, H.A. Hogan, and M.D. Delp. (2002). Site- and compartment- specific changes in bone with hindlimb unloading in mature adult rats. Bone 31 (1): 149-157.

Bloomfield, S.A., H.A. Hogan, and M.D. Delp. (2002). Decreases in bone blood flow and bone material properties in aging Fischer-344 rats. Clin. Orthop. Rel. Res. 396: 248- 257.

Bloomfield, S.A. (2001). Cellular and molecular mechanisms for the bone response to mechanical loading. Int. J. Sport Nutr. Exer. Metabol. 11 (Suppl): S128-136. Colleran, P.N., M.K. Wilkerson, S.A. Bloomfield, L.J. Suva, R.T. Turner, and M.D. Delp.

(2000). Alterations in skeletal perfusion with simulated microgravity: a possible mechanism for bone remodeling. J. Appl. Physiol. 89: 1046-1054.

Inman, C. L., G.L. Warren, H.A. Hogan, and S.A. Bloomfield. (1999). Mechanical loading attenuates immobilization-induced reductions in bone mass and strength. J. Appl. Physiol. 87 (1): 189-195.

Turner, R.T., T.J. Wronski, M. Zhang, L.S. Kidder, S.A. Bloomfield, and J.D. Sibonga. (1998). Effects of ethanol on gene expression in rat bone: transient dose-dependent changes in mRNA levels for matrix proteins, skeletal growth factors, and cytokines are followed by reductions in bone formation. Alcohol. Clin. Exper. Res. 22 (7): 1591-1599.

Bloomfield, S.A., B.E. Girten, and S.E. Weisbrode. (1997). Effects of vigorous exercise training and ∃-agonist administration on bone response to hindlimb suspension. J. Appl. Physiol. 83 (1): 172-178.

Convertino, V.A., S.A. Bloomfield, and J.E. Greenleaf. (1997). An overview of the issues:

physiological effects of bed rest and restricted physical activity. Med. Sci. Sports Exerc. 29 (2): 187-190.

Bloomfield, S.A. (1997). Changes in musculoskeletal structure and function with prolonged bedrest. Med. Sci. Sports Exerc. 29 (2): 197-206.

Bloomfield, S.A., W. J. Mysiw, and R.D. Jackson. (1996). Bone mass and endocrine adaptations to training in spinal cord injured individuals. Bone 19 (1):61-68.

Warren, G.L., D.A. Lowe, C. Inman, O.M. Orr, H.A. Hogan, S.A. Bloomfield, and R.B. Armstrong. (1996). Estradiol effect on anterior crural muscles: tibial bone relationship and susceptibility to injury. J. Appl. Physiol. 80 (5):1660-1665.

Bloomfield, S.A., R.D. Jackson, and W.J. Mysiw. (1994). Catecholamine response to exercise and training in individuals with spinal cord injury. Med. Sci. Sports Exerc. 26 (10): 1213-1219.

Bloomfield, S.A., R.D. Jackson, N.I. Williams, and D.R. Lamb. (1993). Non-weightbearing exercise may increase lumbar spine bone mineral density. Amer. J. Phys. Med. Rehabil. 72:204-209.

Sherman, W.M., J.M. Lash, J.C. Simonsen, and S.A. Bloomfield. (1992). Effects of downhill running on responses to an oral glucose challenge. Int. J. Sport Nutr. 2:251-259.

Martin, W.H. III, E.F Coyle, S.A Bloomfield, and A.A Ehsani, (1986). Effects of physical deconditioning after intense endurance training on left ventricular dimensions and stroke volume. J. Amer. Coll. Cardiol. 7:982-989.

Ward, K.M., and S.A.Bloomfield. (1986). Clinical laboratory services in preventive,

9rehabilitative and research-related exercise programs. J. Med. Technol. 3(12): 604-608.

Coyle, E.F., W.H. Martin III, S.A. Bloomfield, O.H. Lowry, and J.O. Holloszy. (1985). Effects of detraining upon responses to submaximal exercise. J. Appl. Physiol. 59(3): 853-859.

Martin, W.H. III, G.W Heath, E.F Coyle, S.A., Bloomfield, J.O. Holloszy, and A.A. Ehsani. (1984). Effect of prolonged intense endurance training on systolic time intervals in patients with coronary heart disease. Am. Heart J. 107(1):75-81.

Heath, G.W., J.R.Gavin III, J.M Ponser, J.M.Hagberg, S.A. Bloomfield, and J.O. Holloszy,. (1983). Effects of exercise and lack of exercise on glucose tolerance and insulin sensitivity. J. Appl. Physiol. 55(2):512-517.

Coyle, E.F., W.H. Martin, III, A.A.Ehsani, J.M. Hagberg, S.A. Bloomfield, D.R. Sinacore, and J.O.Holloszy. (1983). Blood lactate threshold in some well-trained ischemic heart disease patients. J. Appl. Physiol. 54(1):18-23.

Ehsani, A.A., W.H. Martin, III, G.W. Heath, and S.A. Bloomfield. (1982). Left ventricular response to graded isometric exercise in patients with coronary heart disease. Clin. Physiol. 2:215-224.

Gisolfi, C.V., F. Mora, S.A. Bloomfield, M. Beattie, and S. Magnes. (1980). Effects of apomorphine and pimozide on temperature regulation during exercise in the rat. J.Appl. Physiol. 49(3):363-366.

Papers in Review/Preparation Swift, S.N., K. Baek and S. Bloomfield. (In preparation). Moderate treadmill training mitigates negative impact of restricted dietary intake of calcium and energy. Baek, K. and S. Bloomfield. (In preparation). Contribution of altered beta-adrenergic signaling to bone loss incurred with dietary energy restriction. Nilsson, M.I., J. M. Swift, K. Baek, J.L. Stallone, and S.A. Bloomfield. (In preparation). Confounding effects of single housing on the rat skeleton: a review. Swift, J.M. and S. A. Bloomfield. (In preparation). Beta-adrenergic receptor agonist

administration during hindlimb unloading attenuates losses in bone geometry, structure, and mechanical properties.

Allen, M.R. and S.A. Bloomfield. (In preparation) Hindlimb unloading attenuates marrow ablation-induced increase in cancellous bone formation rate via reduction of mineralizing surface.

Allen, M.R., S.A. Bloomfield, H.A. Hogan. (In preparation) pQCT image pixel intensity is highly correlated to mechanical properties of cancellous bone.

Smith, C.L., M.R. Allen, S.A. Bloomfield, N.L. Weigel. (In preparation) Mitigation of bone loss in ovariectomized rats during simulated microgravity by the estrogen receptor agonist raloxifene.

Smith, C.L., M.R. Allen, S.A. Bloomfield, R. Naryanan, N.L. Weigel. (In preparation) Mitigation of unloading-induced bone loss in male rats by estrogen receptor agonists.

Narayanan, R., M.R. Allen, S.A. Bloomfield, C.L. Smith, and N. L. Weigel. (In preparation) Down-regulation of Vitamin D receptors in the gut with hindlimb suspension: effect of Vitamin D and D receptor agonists, Seocalcitol and Leo A. Published Abstracts Swift, S.M., E.S. Greene, M.J. De Souza, and S.A. Bloomfield. (2009) Thresholds for bone

10loss with energy restriction change with exercise status. FASEB J. 23: 720.9

Hogan, H.A., J.M. Swift, M.I. Nilsson, and S.A Bloomfield. (2008). Effects of simulated resistive exercise on cortical bone in the tibia mid-diapyhsis of hindlimb unloaded rats. J. Bone Miner. Res. 23 (Suppl. 1): S232.

Swift, J.M., S.D. Bouse, M.I. Nilsson, and S.A. Bloomfield. (2008) High-intensity muscle stimulation has an anabolic effect on unweighted tibia And maintains ankle plantar-flexor strength. The Physiologist. 51: 40.

Swift J.M., S.N. Swift, and S.A. Bloomfield. (2008) Beta-adrenergic receptor agonist administration during hindlimb unloading effectively mitigates reductions in cancellous bone formation. J. Bone Miner. Res. 23 (Suppl. 1): S231.

Swift, S.N., K. Baek, M. J. DeSouza, and S.A. Bloomfield. (2008). Treadmill exercise provides only short-term protection against cancellous bone loss with reduced dietary energy intake: endocrine mechanisms. J. Bone Miner. Res. 23 (Suppl. 1): Sxxx.

Sumner, L.R., M.I Nilsson, J.M. Swift, J.M. Jeffery, C.J. Walthall, J.L. Stallone, S.A. Bloomfield, H.A. Hogan. (2007). Electrically stimulated eccentric muscle contraction benefits bone in the tibia of hindlimb unloaded rats at both the mid-diaphysis and proximal metaphysis. J. Bone Miner. Res. 22 (Suppl. 1): S488.

Nilsson, M.I., J.M. Swift, C.J. Walthall, J.L. Stallone, H.A. Hogan, J.D. Fluckey, S.A. Bloomfield. (2007). The effect of resistance exercise on in vivo-derived tomography measures and mechanical properties of rodent bone: is more load always better? J. Bone Miner. Res. 22 (Suppl. 1): S490.

Miller, S.N., K. Baek, M.I. Nilsson, J.L. Stallone, J. Lemmon, H.A. Hogan, S.A. Bloomfield. (2007). Restricting detary protein may improve skeletal integrity in exercising female rats J. Bone Miner. Res. 22 (Suppl. 1): S321.

Swift, J.M., J.T. Ali, J.L. Stallone, H.A. Hogan, S.A. Bloomfield. (2007) Beta-adrenergic receptor agonist administration during hindlimb unloading attenuates losses in bone geometry, structure, and mechanical properties. J. Bone Miner. Res. 22 (Suppl. 1): S134.

Baek, K., J.L. Stallone, and S.A. Bloomfield. (2007) Beta-blockade mitigates bone loss during energy restriction partially via leptin. J. Bone Miner. Res. 22 (Suppl. 1): S.

Nilsson, M., J.M. Swift, K. Baek, and S. Bloomfield. (2007). Amplification of the anabolic response of bone to intermittent PTH injections after disuse. FASEB J. 21: LB118.

Nilsson, M., J.M. Swift, J.L. Stallone, K. Baek, and S. Bloomfield. (2006) Reduced mechanical loading does not diminish the anabolic response of bone to intermittent PTH. J Musculoskel. Neuron. Interact. 6 (4): 397.

Swift, J.M., F. von Walden, T. Elman, J.D. Fluckey, and S.A. Bloomfield. (In press). Assessing the efficacy of multiple dosing regimens of a β-agonist agent for bone and muscle loss during 28-day hindlimb unloading. J Musculoskel. Neuron. Interact. 6 (4): 399.

Baek, K., S. Miller, J. Lemmon, M. Nilsson, and S.A. Bloomfield. (2006) Energy and calcium deficits are major contributors to effect of global food restriction on metaphyseal bone in exercising rodents. J. Bone Miner. Res. 21 (Suppl. 1): S419.

Hogan, H.A., J.D. Alcorn, B.A. Vyvial, and S.A. Bloomfield. (2006) Simulated resistive exer- cise benefits bone in hindlimb unloaded rats. J. Bone Miner. Res. 21 (Suppl. 1): S151.

J.M. Swift, Nilsson, M., K. Baek, and S. Bloomfield. (2006) Reduced mechanical loading does not diminish the anabolic response of bone to intermittent PTH. Med. Sci. Sport Exerc. 36 (5, Suppl): S534.

Alcorn, J.D., Vyvial, B.A., Bloomfield, S.A., Hogan, H.A. (2006) Exercise improves the

11strength of bone in the proximal tibia of hindlimb unloaded mature rats. J. Biomechanics, 39 (Suppl. 1): S13.

Baek, K. and S.A. Bloomfield (2005) Beta-blockade mitigates bone loss with hindlimb unloading. J. Bone Miner. Res. 20 (Suppl. 1): F176. Hogan, H.A., B.A. Vyvial, J.D. Alcorn, J.M. Swift, R.D. Prisby, S.A. Bloomfield, and M. D Delp. (2005) Alterations in the mechanical properties of bone due to Type II diabetes. J. Bone Miner. Res. 20 (Suppl. 1): S422. Swift, J.M., M.R. Allen, H.A. Hogan, S.A. Bloomfield. (2005). Intermittent PTH restores

cancellous BMD and mechanical properties during recovery from hindlimb unloading. Med. Sci. Sport Exerc. 37 (5, Suppl): S150-151.

Prisby, RD., S.A. Bloomfield, J.L.Stallone, and M.D. Delp. (2004) Reduced femoral artery endothelium-dependent vasodilation occurs concurrently with femoral bone loss in Type II diabetic rats. Physiologist 47(4): 286.

Swift, J.M., T.F. Kennedy, S.A. Bloomfield. (2004) Intermittent PTH during recovery from hindlimb unloading: impact on mechanical properties and bone formation rate in cortical bone. Physiologist 47(4): Integrative Biology of Exercise Meeting Proceedings Addendum.

Narayanan, R., C. Seng, N. L. Weigel, S.A. Bloomfield, C.L. Smith. (2004) Attenuation of disuse-induced bone loss by estrogen and Vitamin D receptor ligands in unloaded and

ambulatory female rats. J. Bone Miner. Res. 19 (Suppl 1): S482. Baek, K., A. Currado, M. Allen, S. Bloomfield. (2004). Effect of food restriction and

hindlimb unloading on serum leptin and histomorphometric measures of cancellous bone. J. Bone Miner. Res. 19 (Suppl 1): S434.

Bloomfield, S.A., K. Baek, J.L. Stallone, M.R. Allen. (2004). Intermittent PTH during recovery replaces cancellous bone lost during hindlimb unloading by increasing bone formation rate. FASEB J. 18(4): A691.

Baek, K., J.L. Stallone, S.A. Bloomfield. (2004). Beta-blockade mitigates bone loss with hindlimb unloading. FASEB J. 18(4): A758.

Bloomfield, S.A., M. R. Allen, H. Lemon, H.A. Hogan. (2003). PTH replaces cancellous bone lost during 28 days of hindlimb unloading in skeletally mature rats. J. Bone Miner.

Res. 18 (Suppl 2): S11. Kohn, D.H., J.M. Wallace, R.M. Rajacher, X. Chen, S. Shi, M.R. Allen, S.A. Bloomfield,

P.G. Robey, and M.F. Young. (2003) Rescuing the phenotype of biglycan-deficient mice via exercise. J. Bone Miner. Res. 18 (Suppl 2): S45.

Sajid, M., C. Nolan, M.R. Allen, S.A. Bloomfield, C.L. Smith. (2003). Changes in gene expression by estrogen receptor ligands in the femora of hindlimb unloaded male rats. J. Bone Miner. Res. 18(Suppl 2): S179.

Allen, M.R. and S.A. Bloomfield. (2003). Absence of mechanical load results in an attenuation of marrow ablation-induced increase in cancellous bone formation rate. J. Bone Miner. Res. 18 (Suppl 2): S332.

Baek, K., A.Currado, M.R. Allen, and S.A. Bloomfield. (2003) Comparison of serum leptin concentration under simulated microgravity condition or food restriction or combination of two. J. Bone Miner. Res. 18 (Suppl 2): S333.

Allen, M.R. and S.A. Bloomfield. (2003). Mechanisms for reduced osteoblast activity with unloading of bone. Med. Sci. Sport Exerc. 35 (5, Suppl): S4. Bloomfield, S.A. and M.R. Allen. (2003). Pronounced mismatch of bone density and

muscle strength during recovery from long-term hindlimb unloading. Med. Sci. Sport

12Exerc. 35 (5, Suppl): S77.

Song, W., J.M. Lawler, and S.A. Bloomfield. (2003) Hindlimb unloading increases iNOS protein expression and NF-kappaB DNA binding activity in rat skeletal muscle. FASEB J. 17: A945.

Allen, M.R., H.A. Hogan, and S.A. Bloomfield. (2002). Bone and muscle recovery after 28 days of hindlimb unloading in mature male rats. J Bone Miner Res. 17(Supp 1): S434.

Bloomfield, S.A., M.R. Allen, C. Nolan, and C.L. Smith. (2002). Attenuation of disuse bone loss by estrogen and raloxifene in mature male rats. J Bone Miner Res. 17

(Supp1): S433. Nielsen, K.L., M.R. Allen, S.A. Bloomfield, I. A. Timm, X.D. Chen, M.F. Young, and A. Heegard. Biglycan deficiency interferes with ovariectomy-induced bone loss. J Bone Miner Res. 17 (Supp1): S170.

Dart, L., M. Horea, M.R. Allen, S.A. Bloomfield, and N.M. DiMarco. (2002). A new

method for the measurement of regional bone mass. Med. Sci. Sport Exerc. 34 (5, Suppl): S59.

Allen, M.R., M.F. Young, and S.A. Bloomfield. (2002). Absence of biglycan results in periosteal bone accrual at metaphyseal and mid-diaphyseal sites in unloaded mouse tibiae. Trans.48th Ann. Mtg. Orthop. Res. Soc. [published on CD-ROM]

Allen, M.R., A.C. Currado, and S.A. Bloomfield. (2001). Cancellous bone loss in adult rats following reduction in chow calcium and vitamin D contents to NRC-recommended levels. J Bone Miner Res. 16 (Supp 1): S279.

Allen, M.R., J.L. Stafinsky, C. Nolan, S.A Bloomfield, and C.L. Smith. (2001). Raloxifene attenuates bone loss in mechanically unloaded, ovariectomized female rats. J Bone Miner Res. 16 (Supp 1): S414.

Chen, X.D., M.R. Allen, S.A. Bloomfield, T. Xu, and M. Young. (2001). Biglycan deficient mice have delayed bone formation after bone marrow ablation. J Bone Miner Res. 16 (Supp 1): S450.

Narayanan, R., M.R. Allen, J.L. Stafinsky, S.A. Bloomfield, C.L. Smith, N.L. Weigel. (2001). Effect of 1,25 (OH)2D3 and EB1089 on bone cells and bones of hindlimb unloaded adult male rats. J Bone Miner Res. 16 (Supp 1): S432.

Hogan, H.A., M.R. Allen, W.E. Rogers, and S.A. Bloomfield. (2001). 1,25(OH)2D3 and EB1089 produce higher femoral cancellous bone density after 28-d hindlimb unloading while only 1,25(OH)2D3 enhances material properties. J Bone Miner Res. 16 (Supp 1): S484.

Allen, M.R. and S.A. Bloomfield. (2001). Periosteal resorption at the proximal tibia metaphysis due to mechanical unloading: evidence from longitudinal pQCT measurements. J. Musculoskel. Neuron. Interact. (2)1:

Allen, M.R. and S.A. Bloomfield. (2001). Mature rat skeletal changes in response to simulated microgravity: a gender comparison. Med. Sci. Sport Exerc. 33 (5, Suppl): S299.

Bloomfield, S.A., M.R. Allen, M. Zhang, and R. Turner. (2001). Greater deficit of bone formation in the mature adult rat with 28-d hindlimb unloading. FASEB J. 15(5): A1113.

Hogan, H.A., M.R. Allen, L.P. Nguyen, and S. Bloomfield. (2001). Relations between cancellous bone mechanical properties and bone mineral density in the proximal tibia of the rat. Trans. 47th Ann. Mtg. Orthop. Res. Soc. (Feb, 2001) 26: 521.

Allen, M.R., S.E. Gordon, B. Davis, M.L. Fiorotto, R.J. Schwartz, F.W. Booth, S.A. Bloomfield. (2000). Skeletal muscle IGF-I overexpression alters bone development

13and prevents short-term hindlimb unloading bone loss in adult mouse tibia. J. Bone

Miner.Res. 15 (Suppl 1): S368. Allen, M.R., M. Zhang, R.T. Turner, and S.A. Bloomfield. (2000). Short-term hindlimb

unloading alters TGF-β and cytokine gene expression in femur and humeri of rats. J. Aging Phys. Activity 8(3): 276-277.

Bloomfield, S.A. (2000). Cellular and molecular responses to altered loading of bone. Journal of Aging and Physical Activity 8(3): 247.

Hubal, M.J., C.P. Ingalls, M. Allen, J.C. Wenke, and S.A. Bloomfield. (2000). Effects of eccentric exercise training on mouse skeletal muscle and bone. Med. Sci. Sport Exerc. 32(5, Suppl): S270.

Allen, M.R., L.W. Schultheis, C.B.Ruff , H.A. Hogan, J.R. Shapiro, and S.A. Bloomfield. (2000). Ibandronate increases femoral neck bone mineral content, area, and ultimate

strength in ambulatory and hindlimb unloaded rats. Med. Sci. Sport Exerc. 32(5, Suppl):S270.

Demaree, S.R., J.M. Lawler, M.R. Allen, and S.A. Bloomfield. (2000). Alterations in Antioxidant status in the rat soleus with hindlimb suspension. Med. Sci. Sport Exerc.

32(5, Suppl): S104. Schultheis, L., S. Rastogi, C. Ruff, S. Bloomfield, J. Shapiro. (2000). Partial weightbearing

with a force spectrum typical of normal ambulation improves bone strength in hind-quarter suspended rats. Trans. 46th Ann. Mtg. Orthop. Res. Soc. March, 2000: 724.

Schultheis, L., C.B. Ruff, S.A. Bloomfield, H.A. Hogan, N. Fedarko, M. Thierry-Palmer, J. Ruiz, and J.R. Shapiro. (1999). Disuse bone loss in hindquarter suspended rats: Partial weight-bearing, exercise and ibandronate treatment as countermeasures. J. Bone Miner.Res. 14 (Suppl 1): S537.

Allen, M.R., C.P. Ingalls, G.L. Warren, and S.A. Bloomfield. (1999). Time course of bone and muscle alterations after hindlimb suspension and 24-hour reambulation in mice. J. Bone Miner.Res. 14 (Suppl 1): S217. Delp, M.D., P.N. Colleran, M.K. Wilkerson, E.P. Lorenz, M.R. Allen, H.A. Hogan, L.J. Suva, and S.A. Bloomfield. (1999). Short-term hindlimb unloading diminishes bone mineral density, area, and blood flow in rats. J. Bone Miner.Res. 14 (Suppl 1): S315. Bloomfield, S.A., H.A. Hogan, E.T. Dresser, and J.A. Groves. (1998). Alterations in

pQCT-derived bone geometry and volumetric density and in structural properties of femoral neck in senescent rats Bone 13 (Suppl 1): S437.

Bloomfield, S.A., E.T. Dresser, and M.D. Delp. (1998). Age-induced alterations of bone tissue blood flow and vascular resistance in Fischer 344 rats. Med. Sci. Sports Exerc. 30 (5, Suppl): S293.

Bloomfield, S., X.Wu, R. Zhang, and D.J. Simmons. (1997). Localizing the gene expression response to mechanical loading in tibial bone cells. Med. Sci. Sports Exerc. 29 (5,Suppl): S111.

Wu, X. and S.A. Bloomfield. (1997). Calcium deficiency reduces cortical bone ash weight but not strain response to loading. Med. Sci. Sports Exerc. 29 (5,Suppl): S99.

Bloomfield, S., C.L. Inman, and X. Wu. (1996). Loss of bone strength with calcium deficiency and disuse attenuated by in vivo mechanical loading. J. Bone Miner. Res. 11 (Suppl 1): S269.

Inman, C.L. and S.A. Bloomfield. (1996). In vivo mechanical loading attenuates loss of bone strength with immobilization and calcium deficiency. Med. Sci. Sports Exerc. 25 (5,Suppl):S102.

Bloomfield, S.A., G.L. Warren III, C.L. Inman, and R.B. Armstrong. (1995). Early enzyme changes in murine tibiae after high-force muscle contractions. J. Bone Miner. Res. 10

14(Suppl 1): S409.

Warren, G.L. III, D.A. Lowe, C. Inman, O.M. Orr, H.A. Hogan, S.A. Bloomfield, and R.B. Armstrong. (1995). Estradiol effect on anterior crural muscles:tibial bone relationship and susceptibility to injury. Med. Sci. Sports Exerc. 27 (5,Suppl): S159.

Bloomfield, S.A. and R.D. Jackson. (1994). Variations in bone density independent of estrogen status in female athletes: a multi-sport comparison. Med. Sci. Sports Exerc. 26 (5,Suppl): S98.

Bloomfield, S., R. Jackson, W.J. Mysiw, and S. Hannum, (1992). Catecholamine response to acute exercise in spinal cord injury: effect of training. Med. Sci. Sports Exerc. 24 (5, Suppl): S32.

Bloomfield, S.A., W.J. Mysiw, and R.D. Jackson. (1991). Changes in bone mass and calcium metabolism in chronic spinal cord injury with functional electrical stimulation ergometry and calcium supplementation. J. Bone Miner. Res. 6 (Suppl 1): S128.

Jackson, R.D., W.J. Mysiw, and S.A.Bloomfield. (1991). Functional electrical stimulation

induced muscle contraction reduces bone loss and improves calcium homeostasis in acute spinal cord injury. J. Bone Miner. Res. 6(Suppl 1): S127.

Jackson, R.D., W.J. Mysiw, and S.A.Bloomfield. (1991). Changes in insulin-like growth factors I and II after functional electrical stimulation cycle ergometry. Arch. Phys. Med. Rehabil. 72:786.

Jackson, R.D., S.A. Bloomfield, and W.J. Mysiw. (1990). Effect of functional electrical stimulation cycle ergometry on calcium and bone metabolism in chronic spinal cord injury. Arch. Phys. Med. Rehabil. 71:786.

Mysiw, W.J., S. Hannum, S.A. Bloomfield, V. Yost, and R.D. Jackson. (1990). Effect of lower extremity functional electrical stimulation on upper extremity aerobic capacity. Arch. Phys. Med. Rehabil. 71:829.

Mysiw, W.J., S.A Bloomfield, and R.D. Jackson. (1990). Hypercalciuria prevented by functional electrical stimulation. Arch. Phys. Med. Rehabil. 71:795.

Bloomfield, S.A., R.D. Jackson, W.J. Mysiw, S. Hannum, and V. Yost. (1990). Can functional electrical stimulation cycle ergometry reverse disuse osteopenia in chronic spinal cord injury? J. Bone Miner. Res. 5(Suppl 2):S247.

Bloomfield, S.A., W.J. Mysiw, and R.D. Jackson. (1990). Changes in regional bone mineral density with immobilization due to spinal cord injury. Med. Sci. Sports Exerc. 22 (2,Suppl): S76.

Plato, P., D.R. Lamb, B. Girten, J. Schlub, and S. A. Bloomfield. (1990). Plasma insulin-like growth factor I in sedentary and trained rats after hindlimb suspension and dobutamine treatments. Med. Sci. Sports Exerc. 22 (2, Suppl):S32.

Bloomfield, S.A., R.D. Jackson, D.R. Lamb, and N.I. Williams. (1989). Non-weightbearing exercise can increase trabecular bone mineral density. Med. Sci. Sports Exerc. 21 (2):S114.

Girten, B., B. Smith, S.A. Bloomfield, A.J. Merola, C. Oloff, and L. Kazarian. (1989). Ventricular myosin isozyme and electrocardiographic alterations after exercise and interventions for hypokinesia/hypodynamia deconditioning. Aviat. Space Environ. Med. 60 (5):501.

Bloomfield, S.A., R.D. Jackson, M. Meyers, and B. Bossetti. (1987). Differential effects of exercise on bone mass in female athletes. Fed. Proc. 46 (3): 492.

Girten, B., C. Oloff, L. Kazarian, S.A. Bloomfield, B. Smith, and R. Hamlin. (1987). Effects of dobutamine on suspension hypokinesia/hypodynamia deconditioning in

15rats. Aviat. Space Environ. Med. 58 (5): 501.

Ehsani, A.A., D.R. Biello, S.A. Bloomfield, and J.O. Holloszy. (1982). Exercise training improves intrinsic left ventricular performance in ischemic heart disease. Clin. Res. 30 (2): 480A.

Symposium Proceedings And Technical Research Reports Bloomfield, S.A. (2006) Does altered blood flow to bone in microgravity impact on

mechanotransduction? J. Musculoskelet. Neuronal Interact. 6(4): 324-326. Bloomfield, S.A. (2006) Summary---Bone in Microgravity Environments: “Houston, we

have a problem” J. Musculoskelet. Neuronal Interact. 6(4): 329-330. Bloomfield, S.A. (Lead writer for Musculoskeletal Physiology Workgroup) (2003). Sex,

Space, and Environmental Adaptation: A National Workshop on Research Priorities on Sex Differences in Human Responses to Challenging Environments. [Sponsored by NASA and U-MO Center for Gender Physiology and Environmental Adaptation; November 12-14, 2002; University of Missouri, Columbia MO.]

Bloomfield, S.A. (2001). Optimizing bone health: Impact of nutrition, exercise, and hormones. Gatorade Sports Science Institute Sports Science Exchange. 14 (3): 1- 4. Cavanagh, P. and S. Bloomfield. (2001). Decrements in bone, connective tissue and

muscle function with prolonged spaceflight: mechanisms and countermeasures. (CD- ROM) Proceedings, BioAstronautics Investigator’s Workshop. January 17-19, 2001; Galveston, TX. Schultheis, L., M. Daphtary, C. Ruff, S. Bloomfield, H. Hogan, M. Thiery-Palmer, N.

Fedarko, and J. Shapiro. (2001). The effects of partial weightbearing, mechanical loading and ibandronate on skeletal tissues in the adult rat hindquarter suspension model of microgravity. (CD-ROM) Proceedings, BioAstronautics Investigator’s Workshop. January 17-19, 2001. Galveston, TX.

Bloomfield, S.A., B. Girten, S. Weisbrode, E. Eveland, and L. Kazarian. (1989). Modifications of bone atrophy seen with hindlimb suspension by exercise and dobutamine. The Physiologist 32(1, Suppl):S27-S28.

Bloomfield, S.A. (1997). Book review: Calcium and Phosphorus in Health and Disease, J.J.B. Anderson and S.C. Garner (ed). Med. Sci. Sports Exerc. 29(1): 160.

RESEARCH PRESENTATIONS (Invited presentations noted, n=16 ; co-authors who are my graduate student advisees are noted in italics) International And National Bloomfield, S.A., S.N. Swift, M.J. DeSouza, E.S. Greene, and F. Lima. (April, 2009)

Endurance training minimizes alterations in IGF-I and skeletal mass, but not fat mass or leptin, during prolonged energy restriction. Poster presentation at ASMBR-NIH Special

Topics meeting: Bone-Fat-Brain Connections, Bethesda, MD. Swift, S.M., E.S. Greene, M.J. De Souza, and S.A. Bloomfield. (April, 2009) Thresholds for

bone loss with energy restriction change with exercise status. Poster presentation at Experimental Biology Annual Meeting, New Orleans, LA; also presented as an oral slide talk at American Society of Nutrition Proctor & Gamble Travel Scholars session.

Swift, J.M., S.D. Bouse, M.I. Nilsson, and S.A. Bloomfield. (September, 2008). High intensity muscle stimulation has an anabolic effect on unweighted tibia And maintains ankle plantar-flexor strength. Poster presentation at the Integrative Biology of Exercise/American Physiological Society meeting, Hilton Head, South Carolina.

Swift J.M., S.N. Swift, and S.A. Bloomfield. (September, 2008). Beta-adrenergic receptor

16agonist administration during hindlimb unloading effectively mitigates reductions in cancellous bone formation. Poster presentation at 30th Annual Meeting of the American Society for Bone and Mineral Research, Montreal, Quebec, Canada.

Hogan, H.A., J.M. Swift, M.I. Nilsson, and S.A Bloomfield. (September, 2008). Effects of simulated resistive exercise on cortical bone in the tibia mid-diapyhsis of hindlimb unloaded rats. Poster presentation at 30th Annual Meeting of the American Society for Bone and Mineral Research, Montreal, Quebec, Canada.

Swift, S.N., K. Baek, M. J. DeSouza, and S.A. Bloomfield. (2008, September). Treadmill exercise provides only short-term protection against cancellous bone loss with reduced dietary energy intake: endocrine mechanisms. Poster presentation at 30th Annual Meeting of the American Society for Bone and Mineral Research, Montreal, Quebec, Canada.

Swift, S.N., K. Baek, M. J. DeSouza, and S.A. Bloomfield. (2008, September). Treadmill exercise provides only short-term protection against cancellous bone loss with reduced dietary energy intake: endocrine mechanisms. Oral presentation to Physical Activity and Fall Prevention Working Group, 30th Annual Meeting of the American Society for Bone and Mineral Research, Montreal, Quebec, Canada. (Invited)

Swift, S.N., K. Baek, M.J. DeSouza, and S.A. Bloomfield. (2008, August). Dietary energy deficits leading to weight loss can induce loss of cancellous bone. Poster presented at the 38th Sun Valley Workshop on Skeletal Tissue Biology, Sun Valley, Idaho.

Swift J.M., S.N. Swift, and S.A. Bloomfield. (2008, August). Beta-adrenergic receptor agonist administration during hindlimb unloading effectively mitigates reductions in cancellous bone formation. Poster presented at the 38th Sun Valley Workshop on Skeletal Tissue Biology, Sun Valley, Idaho.

Bouse, S.D., J.M. Swift, S.A Bloomfield, and H.A Hogan. (2008, June). Analysis of in-vivo strains in the tibial metaphysis of adult rats during voluntary exercising protocols. Oral presentation, Bone Mechanics Session, 2008 Summer Bioengineering Conference, Marco Island, FL.

Bouse, S.D., J.M. Swift, S.A Bloomfield, and H.A Hogan. (2008, February). A comparison of in-vivo bone strains in rats conducting two different jumping exercises. Poster presentation, 25th Annual Houston Conference on Biomedical Engineering Research, Houston Society for Engineering in Medicine and Biology, Houston, TX.

Bloomfield, S.A. (2008, June). Energy restriction and bone loss during spaceflight: What’s the connection? Oral symposium presentation: International Society for Gravitational Physiology/European Space Agency Joint Meeting, Angers, France. (Invited)

Baek, K., J.L. Stallone, and S.A. Bloomfield. (2007, September) Beta-blockade mitigates bone loss during energy restriction partially via leptin. Oral presentation at 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI.

Sumner, L.R., M.I. Nilsson, J.M. Swift, J.M. Jeffery, C.J. Walthall, J.L. Stallone, S.A. Bloomfield, H.A. Hogan. (2007, September) Electrically stimulated eccentric muscle contraction benefits bone in the tibia of hindlimb unloaded rats at both the mid-diaphysis and proximal metaphysis. Poster presentation at 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI.

Nilsson, M.I., J.M. Swift, C.J. Walthall, J.L. Stallone, H.A. Hogan, J.D. Fluckey, S.A. Bloomfield. (2007, September). The effect of resistance exercise on in vivo-derived

tomography measures and mechanical properties of rodent bone: is more load always better? Poster presentation at 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI.

17 Miller, S.N., K. Baek, M.I. Nilsson, J.L. Stallone, J. Lemmon, H.A. Hogan, S.A. Bloomfield.

(2007, September). Restricting dietary protein may improve skeletal integrity in exercising female rats. Poster presentation at 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI.

Swift, J.M., J.T. Ali, J.L. Stallone, H.A. Hogan, S.A. Bloomfield. (2007, September). Beta- adrenergic receptor agonist administration during hindlimb unloading attenuates losses in bone geometry, structure, and mechanical properties. Plenary poster presentation, 29th Annual Meeting of the American Society for Bone and Mineral Research, Honolulu, HI.

Jeffery, J.M., M.C. Murphey, J.L. Stallone, S.A. Bloomfield, H.A. Hogan (2007, June). Characterizing Strain in the Tibia of Rats Exposed to Hindlimb Unloading with an Exercise Countermeasure. Oral presention at Summer Bioengineering Conference, Keystone, CO.

Bloomfield, S.A. (2007, April). Can exercise alone mitigate bone loss with spaceflight? Translating animal data to in-flight prescriptions for astronauts. Oral symposium presentation: International Society for Gravitational Physiology, San Antonio, TX. (Invited)

Bloomfield, S.A. (2006, November). Bone health in exercising females: impact of calcium, protein, and energy. Pennsylvania State University Noll Laboratory Graduate Seminar, State College, PA. (Invited)

Hogan, H.A., J.D.Alcorn, B.A. Vyvial, and S.A. Bloomfield. (2006, September). Simulated resistive exercise benefits bone in hindlimb unloaded rats. Poster presentation at American Society of Bone and Mineral Research, Philadelphia, PA.

Baek, K., S. Miller, J. Lemmon, M. Nilsson, and S.A. Bloomfield. (2006, September). Energy and calcium deficits are major contributors to effect of global food restriction on metaphyseal bone in exercising rodents. Poster presentation at American Society of Bone and Mineral Research, Philadelphia, PA.

Bloomfield, S.A. (2006, August). Bone health and “swimming plus”. Oral presentation, Sports Medicine Mini-Conference, FINA World Masters Championships, Stanford University, Palo Alto, CA. (Invited)

Bloomfield, S.A. (2006, August). Does altered blood flow to bone in microgravity impact on

mechanotransduction? Oral symposium presentation: 35th International Sun Valley Workshop on Skeletal Tissue Biology, Sun Valley, ID. (Invited, served as chair)

Nilsson, M., J.M. Swift, K. Baek, and S. Bloomfield. (2006, August). Reduced mechanical loading does not diminish the anabolic response of bone to intermittent PTH. Poster presentation: 35th International Sun Valley Workshop on Skeletal Tissue Biology, Sun Valley, ID.

Swift, J.M., F. von Walden, T. Elman, J.D. Fluckey, and S.A. Bloomfield. (2006, August). Assessing the efficacy of multiple dosing regimens of a β-agonist agent for bone and muscle loss during 28-day hindlimb unloading. Poster presentation: 35th International Sun Valley Workshop on Skeletal Tissue Biology, Sun Valley, ID.

Alcorn, J.D., Vyvial, B.A., Bloomfield, S.A., and H.A. Hogan. (2006, July). Exercise improves the strength of bone in the proximal tibia of hindlimb unloaded mature rats. Oral Presentation (H. Hogan), 5th World Congress of Biomechanics, Munich, Germany.

J.M. Swift, Nilsson, M., K. Baek, and S. Bloomfield. (2006, May) Reduced mechanical loading does not diminish the anabolic response of bone to intermittent PTH. Poster presentation at American College of Sports Medicine, Denver, CO.

Bloomfield, S.A. (2006, April). The muscle-bone response to disuse: An integrative

18physiology approach. Advances in Mineral Metabolism Annual Meeting, Snowmass, CO. [Invited]

Hogan, H.A., J. D. Alcorn, B. A. Vyvial, and S. A. Bloomfield. (2006, February). Eccentric muscle contractions prevent loss of bone mass and strength with hindlimb unloading. Poster presentation at 2006 National Space Biomedical Research Institute Retreat, League City, TX .

Alcorn, J.D., H.A. Hogan, B.A.Vyvial, and S.A. Bloomfield. (2006, February). Osteogenic effect of electrical muscle stimulation as a countermeasure during hindlimb unloading. Poster presentation at 23rd Annual Meeting of Houston Society for Engineering in Medicine and Biology, Houston, TX.

Baek, K. and S.A. Bloomfield (2005, September). Beta-blockade mitigates bone loss with hindlimb unloading. Plenary poster presentation at American Society of Bone and Mineral Research, Nashville, TN.

Hogan, H. A., B.A. Vyvial, J.D. Alcorn, J.M. Swift, R.D. Prisby, S.A. Bloomfield, and M.D. Delp. (2005, September). Alterations in the mechanical properties of bone due to Type II diabetes. Poster presentation at American Society of Bone and Mineral Research, Nashville, TN.

Baek, K. and S.A. Bloomfield. (2005, August). Beta-blockade mitigates bone loss with Hindlimb unloading. Poster presentation: 35th International Sun Valley Workshop on Skeletal Tissue Biology, Sun Valley, Idaho.

Bloomfield, S.A. (2005, June). What are the risks to bone health during missions to the Moon and Mars? Bone Loss During Spaceflight Symposium, Cleveland Clinic Foundation, OH. (Invited)

Nilsson, M.I., M. R. Allen, K. Baek, J. Swift, H. A. Hogan, S. A. Bloomfield. (2005, June). Pharmacological and mechanical interventions to accelerate bone recovery after hindlimb

unloading to better match rate of muscle function recovery. Bone Loss During Spaceflight Symposium, Cleveland Clinic Foundation, OH.

Bloomfield, S.A., M.R. Allen, H. Lemmon, H.A. Hogan. (2005, June). Cancellous bone volume is restored by intermittent PTH after mechanical unloading. Oral presentation in Featured Science Symposium “Musculoskeletal Challenges to Long-Duration Spaceflight”, American College of Sports Medicine, Nashville, TN. (Invited)

Swift, J.M., M.R. Allen, H.A. Hogan, S.A. Bloomfield. (2005, June). Intermittent PTH restores cancellous BMD and mechanical properties during recovery from hindlimb unloading. Poster presentation at the Annual Meeting of the American College of Sports Medicine, Nashville, TN.

Narayanan, R., S. Karmakar, C. Seng, Q. He, L.J. Suva, N.L. Weigel, S.A. Bloomfield and C.L. Smith. (2005, January). Evaluation of estrogen and Vitamin D receptor ligands as countermeasures for disuse-induced bone loss in unloaded and ambulatory rats: Are responses to Vitamin D receptor ligands gender-specific? Poster presentation at NASA Bioastronautics Meeting, Galveston, TX.

Bloomfield, S.A., M.R. Allen, K. Baek, J. Swift, and H.A. Hogan. (2005, January). Pharmacological and mechanical interventions to accelerate bone recovery after hindlimb unloading to better match rate of muscle function recovery. Poster presentation at NASA Bioastronautics Meeting, Galveston, TX.

Swift, J.M., T.F. Kennedy, S.A. Bloomfield. (2004, October) Intermittent PTH during recovery from hindlimb unloading: impact on mechanical properties and bone

formation rate in cortical bone. Poster presentation at the APS Integrative Biology of

19 Exercise meeting, Austin, TX.

Narayanan, R., C. Seng, N.L. Weigel, S.A. Bloomfield and C.L. Smith. (2004, October). Attentuation of Disuse-Induced Bone Loss by Estrogen and Vitamin D Receptor Ligands in Unloaded and Ambulatory Female Rats. Poster presentation at American Society of Bone & Mineral Research, Seattle, WA.

Baek, K., A. Currado, M. Allen, S. Bloomfield. (2004, October). Effect of food restriction and hindlimb unloading on serum leptin and histomorphometric measures of cancellous bone. Poster presentation at American Society of Bone & Mineral Research, Seattle, WA.

Bloomfield SA. (2004, May). How animal research has informed the new ACSM position stand on bone health and osteoporosis. Oral slide presentation at Bone Health Summit, University of Toronto, Toronto, CA. (Invited)

Bloomfield, S.A., K. Baek, J.L. Stallone, M.R. Allen. (2004, March). Intermittent PTH during recovery replaces cancellous bone lost during hindlimb unloading by increasing bone formation rate. Poster presentation at Experimental Biology, Washington, D.C

Baek, K., J.L. Stallone, S.A. Bloomfield. (2004, March). Beta-blockade mitigates bone loss with hindlimb unloading. Poster presentation at Experimental Biology, Washington, D.C.

Bloomfield, S.A. (2004, January). Differential recovery of bone and muscle after prolonged disuse: do we need a new strategy? Oral presentation to Dept. of Cellular Biology and Anatomy, Medical College of Georgia, Augusta, GA. (Invited)

Bloomfield, S.A., M. R. Allen, H. Lemon, H.A. Hogan. (September, 2003). PTH replaces cancellous bone lost during 28 days of hindlimb unloading in skeletally mature rats. Oral slide presentation at American Society of Bone and Mineral Research, Minneapolis, MN.

Allen, M.R. and S.A. Bloomfield. (September, 2003). Absence of mechanical load results in an attenuation of marrow ablation-induced increase in cancellous bone formation rate. Poster presentation at American Society of Bone & Mineral Research, Minneapolis, MN.

Baek, K., A.Currado, M.R. Allen, and S.A. Bloomfield. (September, 2003). Comparison of serum leptin concentration under simulated microgravity condition or food restriction or combination of two. Poster presentation at American Society of Bone and Mineral Research, Minneapolis, MN.

Allen, M.R. and S.A. Bloomfield. (2003, May). Mechanisms for reduced osteoblast activity with unloading of bone. Oral presentation: American College of Sports Medicine, San Francisco, CA . (Invited)

Bloomfield, S.A. and M.R. Allen. (2003, May). Pronounced mismatch of bone density and Muscle strength during recovery from long-term hindlimb unloading. Poster presented at the Annual Meeting of the American College of Sports Medicine, San Francisco, CA .

Bloomfield, S.A., C. Smith, M.R. Allen, and H.A. Hogan. (2003, January). Recovery from hindlimb unloading: functional mismatch of bone and muscle. Oral slide presentation: NASA Bioastronautics Meeting, Galveston, TX.

Allen, M.R., H.A. Hogan, and S.A. Bloomfield. (2002, September). Bone and muscle recovery after 28 days of hindlimb unloading in mature male rats. Poster presentation:

American Society of Bone and Mineral Research, San Antonio, TX. Bloomfield, S.A., M.R. Allen, C. Nolan, and C.L. Smith. (2002, September). Attenuation of

disuse bone loss by estrogen and raloxifene in mature male rats. Poster presentation: American Society of Bone and Mineral Research, San Antonio, TX.

Allen, M.R., M.F. Young, and S.A. Bloomfield. (2002, February). Absence of biglycan results

in periosteal bone accrual at metaphyseal and mid-diaphyseal sites in unloaded mouse

20tibiae. Poster presentation: Orthopaedic Research Society, Dallas, TX.

Bloomfield, S.A., M.R. Allen, H.A. Hogan, C.L. Smith, and G.L. Warren. (2002, January). Strain differences in response to hindlimb unloading and reambulation. Poster presentation: 2nd Biennial National Space Biomedical Research Institute Retreat, Galveston, TX.

Allen, M.R., A.C. Currado, and S.A. Bloomfield. (2001, September). Cancellous bone loss in adult rats following reduction in chow calcium and vitamin D contents to NRC-recommended levels. Poster presentation: American Society of Bone and Mineral Research, Phoenix, AZ.

Allen, M.R., J.L. Stafinsky, C. Nolan, S.A Bloomfield, and C.L. Smith. (2001, September). Raloxifene attenuates bone loss in mechanically unloaded, ovariectomized female rats.

Poster presentation: American Society of Bone and Mineral Research, Phoenix, AZ. Allen, M.R. and S.A. Bloomfield. (2001, August). Periosteal resorption at the proximal

tibia metaphysis due to mechanical unloading: evidence from longitudinal pQCT measurements. Poster presentation: University of Utah Hard Tissue Workshop, Sun Valley, ID.

Bloomfield, S.A. and M.R. Allen. (2001, August). Mature rat skeletal changes in response to simulated microgravity: a gender comparison. Poster presentation: University of Utah Hard Tissue Workshop, Sun Valley, ID.

Allen, M.R. and S.A. Bloomfield. (2001, June). Mature rat skeletal changes in response to simulated microgravity: a gender comparison. Poster presented at the Annual Meeting of the American College of Sports Medicine, Baltimore, MD.

Bloomfield, S.A., M.R. Allen, M. Zhang, and R. Turner. (2001, April). Greater deficit of bone formation in the mature adult rat with 28-d hindlimb unloading. Poster presentation: Experimental Biology, Orlando, FL.

Bloomfield, S.A. (2000, October). Bone loss with spaceflight: mechanisms and counter- measures. Oral presentation: Central States Chapter of American College of Sports Medicine, Kansas City, KA. (Invited)

Allen, M.R., S.E. Gordon, B. Davis, M.L. Fiorotto, R.J. Schwartz, F.W. Booth, S.A. Bloomfield. (2000, September). Skeletal muscle IGF-I overexpression alters bone development and prevents short-term hindlimb unloading bone loss in adult mouse tibia. Poster presentation: American Society of Bone and Mineral Research, Toronto, Canada.

Bloomfield, S.A., M.R. Allen, H.A. Hogan. (2000, September). Site-specific changes in bone strength and mineral density with 28-d hindlimb unloading in the mature adult rat. Poster presentation: Integrative Biology of Exercise, American Physiological Society, Portland, ME.

Bloomfield, S.A., M.J. Hubal, M.R. Allen, J.C. Wenke, H.A. Hogan, C.P. Ingalls. (2000, August). Can eccentric exercise training attenuate reductions in bone mechanical properties with estrogen deficiency? Poster presentation: University of Utah Hard Tissue Workshop, Sun Valley, ID.

Bloomfield, S.A. (2000, June). Cellular and molecular aspects of the bone response to altered loading. Oral presentation at the 11th International Conference on the Biochemistry of Exercise, Little Rock, AR. (Invited)

Allen, M.R., M. Zhang, R.T. Turner, and S.A. Bloomfield. (2000, June). Short-term hindlimb unloading alters TGF-B and cytokine gene expression in femur and humeri of

rats. Poster presentation at the 11th International Conference on the Biochemistry of Exercise, Little Rock, AR.

Allen, M.R., L.W. Schultheis, C.B.Ruff , H.A. Hogan, J.R. Shapiro, and S.A. Bloomfield.

21 (2000, June). Ibandronate increases femoral neck bone mineral content, area, and

ultimate strength in ambulatory and hindlimb unloaded rats. Poster presented at the Annual Meeting of the American College of Sports Medicine, Indianapolis, IN. Hubal, M.J., C.P. Ingalls, M. Allen, J.C. Wenke, and S.A. Bloomfield. (2000, June). Effects of eccentric exercise training on mouse skeletal muscle and bone. Poster presented at the Annual Meeting of the American College of Sports Medicine, Indianapolis, IN. Allen, M.R., C.P. Ingalls, G.L. Warren, and S.A. Bloomfield. (1999, September). Time

course of bone and muscle alterations after hindlimb suspension and 24-hour reambulation in mice. Poster presented at the Annual Meeting of the American Society of Bone and Mineral Research, St. Louis, MO.

Bloomfield, S.A. (1999, June). Muscle-bone interactions: evidence from animal models. Oral symposium presentation at the Annual meeting of the American College of Sports

Medicine, Seattle, WA. (Invited) Bloomfield, S.A., H.A. Hogan, E.T. Dresser, and J.A. Groves. (1999, January).

Alterations in pQCT-derived bone geometry and volumetric density and in structural properties of femoral neck in senescent rats. Oral slide presentation at the First Biennial National Space Biomedical Research Investigators Retreat, League City, TX.

Bloomfield, S.A., H.A. Hogan, E.T. Dresser, and J.A. Groves. (1998, December). Alterations in pQCT-derived bone geometry and volumetric density and in structural properties of femoral neck in senescent rats. Poster presented at the Annual Meeting of the American Society of Bone and Mineral Research, San Francisco, CA.

Bloomfield, S.A. (1998, November). Bone loss with disuse and microgravity: can it be prevented? Oral seminar presentation to Kinesiology Department, Pennsylvania State University, State College, PA. (Invited)

Bloomfield, S.A. (1998, November). Endocrine and mechanical loading effects on bone. Oral seminar presentation to Noll Laboratory, Pennsylvania State University, State College, PA. (Invited)

Bloomfield, S.A., H.A. Hogan, E.T. Dresser, and J.A. Groves. (1998, August). Alterations in pQCT-derived bone geometry and volumetric density and in structural properties of

femoral neck in senescent rats. Poster presented at the University of Utah Hard Tissue Workshop, Sun Valley, ID.

Bloomfield, S.A., E.T. Dresser, and M.D. Delp. (1998, June). Age-induced alterations of bone tissue blood flow and vascular resistance in Fischer 344 rats. Poster presented at the Annual Meeting of the American College of Sports Medicine, Orlando, FL.

Bloomfield, S.A., G.L. Warren, H.A. Hogan, J.A. Groves, and R.B. Armstrong. (1997, August). Maintenance of bone mechanical properties in estrogen-deficient mice with high-force muscle contractions. Poster and oral presentation at the University of Utah Hard Tissue Workshop, Sun Valley, ID.

Bloomfield, S.A., X. Wu, R. Zhang, and D.J. Simmons. (1997, May). Localizing the gene expression response to mechanical loading in tibial bone cells. Oral slide presentation at the Annual Meeting of the American College of Sports Medicine, Denver, CO.

Wu, X. and S.A. Bloomfield. (1997, May). Calcium deficiency reduces cortical bone ash weight but not strain response to loading. Poster presented at the Annual Meeting of the American College of Sports Medicine, Denver, CO.

Bloomfield, S.A., C.L. Inman, and X. Wu. (1996, September). Loss of bone strength with calcium deficiency and disuse attenuated by in vivo mechanical loading. Poster presented at the Annual Meeting of the American Society of Bone and Mineral Research, Seattle, WA.

Inman, C.L. and S.A. Bloomfield. (1996, May). In vivo mechanical loading attenuates loss

22of bone strength with immobilization and calcium deficiency. Poster presented at the Annual Meeting of the American College of Sports Medicine, Cincinnati, OH.

Bloomfield, S.A., G.L. Warren, C.L. Inman, and R.B. Armstrong. (1995, September). Early enzyme changes in murine tibiae after high-force muscle contractions. Poster presented at the Annual Meeting of the Amer. Society of Bone and Mineral Research, Baltimore, MD.

Bloomfield, S.A. (1994, June). Exercise in the older adult: bone, ligament and tendon. Oral presentation at the Gatorade Sport Science Institute, Cancun, Mexico. (Invited)

Bloomfield, S.A. and R.D. Jackson.(1994, June). Variations in bone density independent of estrogen status in female athlete: a multi-sport comparison. Poster presented at the Annual Meeting of the American College of Sports Medicine, Indianapolis, IN.

Bloomfield, S.A. (1993, June). Musculoskeletal consequences of deconditioning. Oral presentation for symposium "Physiological Consequences of Bedrest Deconditioning" at the Annual Meeting of the American College of Sports Medicine, Seattle, WA. (Invited)

Bloomfield, S.A., R. Jackson, J. Mysiw, and S. Hannum. (1992, May). Catecholamine res-ponses to acute exercise in spinal cord injury: effect of training. Poster presented at the Annual Meeting of the American College of Sports Medicine Annual Meeting, Dallas, TX.

Bloomfield, S.A., W.J. Mysiw, and R.D. Jackson. (1991, August). Changes in bone mass and calcium metabolism in chronic spinal cord injury with functional electrical stim-ulation cycle ergometry and calcium supplementation. Poster presented at the Annual Meeting of the American Society of Bone and Mineral Research, San Diego, CA.

Bloomfield, S.A., R.D. Jackson, W.J. Mysiw, S. Hannum and V.Yost. (1990, August). Can functional electrical stimulation cycle ergometry reverse disuse osteopenia in spinal cord injury? Poster presented at the Annual Meeting of the American Society of Bone and Mineral Research, Atlanta, GA.

Bloomfield, S.A., W.J. Mysiw, and R.D. Jackson. (1990, May). Changes in regional bone

mineral density with immobilization due to spinal cord injury. Paper presented at the Annual Meeting of the American College of Sports Medicine, Salt Lake City, UT.

Bloomfield, S.A., R.D. Jackson, D.R. Lamb, and N. I. Williams. (1989, May). Non-weight-bearing exercise can increase trabecular bone mineral density. Paper presented at the Annual Meeting of the American College of Sports Medicine, Baltimore, MD.

Bloomfield, S.A., B. Girten, S. Weisbrode, E. Eveland, and L. Kazarian. (1988, October). Exercise training and dobutamine modify bone loss seen with hindlimb suspension. Paper presented at the Fall Meeting of the American Physiological Society, Montreal, Canada.

Bloomfield, S.A., R.D. Jackson, M. Meyers, and B. Bossetti. (1987, March). Differential effects of exercise on bone mass in female athletes. Poster presented at the Annual Meeting of the Federation of American Societies of Experimental Biology, Washington, D.C.

Regional And State (Invited presentations noted, n=4; co-authors who are my graduate student advisees are noted in italics)

Swift, J., MI Nilsson, .LR. Sumner, J.M. Jeffery, H.A. Hogan, and S.A. Bloomfield. (2009, February). Simulated resistance training during hindlimb unloading abolishes disuse bone loss and maintains muscle strength. Oral presentation at Texas Chapter of the

23American College of Sports Medicine, Tyler, TX. (1st place, Student Manuscript Award).

Swift, S.N., K. Baek, J.M. Swift, S.M. Smith, and S.A. Bloomfield. (2009, February). Endurance treadmill training mitigates loss of bone during calcium and energy restriction. Oral presentation at Texas Chapter of the American College of Sports Medicine, Tyler, TX. (4th place, Student Manuscript Award).

Manning, S., S. Swift, E. Greene, D. Koonce, and S.A. Bloomfield. (2009, February). Does 12 weeks of endurance training modify the decrease in skeletal mass and changes in body composition with restricted caloric intake? Poster presentation at Texas Chapter of the American College of Sports Medicine, Tyler, TX. (1st place, Undergraduate Student Posters).

Bloomfield, S.A. (2008, March). Mitigating bone loss with spaceflight: Mission impossible? Oral slide presentation at the Institute for Exercise and Environmental Medicine, Presbyterian Hospital, Dallas, TX; Texas ACSM Spring Lecture Tour (Invited)

Bloomfield, S.A. (2008, March). Negative bone health effects of reduced energy intake: Does exercise change the picture? Oral slide presentation at UT-Medical Branch, Galveston, TX; Dept of Kinesiology, UT-Tyler, TX; and UT-Austin, Austin, TX; Texas ACSM Spring Lecture Tour (Invited)

Nilsson, M.I. R.D. Prisby, J.L. Stallone, J.M. Swift, H.A. Hogan, M.D. Delp, and S.A. Bloomfield. (2007, February) Temporal progression of changes in bone properties in Type 2 diabetes. Poster presentation at Texas Chapter of the American College of Sports Medicine, Arlington, TX. (1st place, Ph.D. Student Category)

MacManus, S., K. Baek, S. N. Miller, J.L. Stallone, and S.A. Bloomfield. (2007, February) Reduced energy intake is the major contributor to the impact of global food restriction on skeletal mass in exercising rodents. Poster presentation at Texas Chapter of the American College of Sports Medicine, Arlington, TX. (2nd place, Undergraduate Student Posters)

Swift, J.M., F. von Walden, T. Elman, J.D. Fluckey, and S.A. Bloomfield. (2006, February).

Assessing the efficacy of multiple dosing regimens of a β-agonist agent for bone and muscle loss during 28-day hindlimb unloading. Poster presentation at Texas Chapter of the American College of Sports Medicine, Denton, TX. (1st place, M.S. student category).

Nilsson, M.I., M.R. Allen, K. Baek, J. Swift, H.A. Hogan, and S.A. Bloomfield. (2006, February). Reduced mechanical loading does not diminish the anabolic response of bone to intermittent PTH. Poster presentation at Texas Chapter of the American College of Sports Medicine (TACSM), Denton, TX. (1st place, Ph.D. student category)

Alcorn, J.D., Hogan, H.A., Vyvial, B.A., Bloomfield, S.A.. (2006, February). Osteogenic Effect of Electric Muscle Stimulation as a Countermeasure during Hindlimb Unloading, Poster presentation at Houston Society for Engineering in Medicine and Biology, Houston, TX. (Sheppard Award for Best Poster).

Swift, J.M., M.R. Allen, H.A. Hogan, and S.A. Bloomfield. (2005, February). Intermittent PTH restores cancellous BMD and mechanical properties during recovery from hindlimb unloading. Poster presentation at Texas Chapter of the American College of Sports Medicine. Arlington, TX. (2nd place, M.S. student category) Bloomfield, S.A. (2005, February). Vascular physiology meets bone: exercise on earth and

flying in space. Texas Chapter of the American College of Sports Medicine, Arlington, TX. (Invited).

24Bloomfield, S.A. (2003, October). Variable recovery of bone and muscle after prolonged

spaceflight: do we need a new strategy? Oral presentation to NASA-Johnson Space Center Flight Surgeon’s Grand Rounds, Clear Lake, TX. (Invited)

Rockman, A.C., K. Baek, M.R. Allen, and S.A. Bloomfield. (2003, February). Hindlimb unloading in mature adult rats alters cortical bone formation activity but not bone mineral density or bone geometry. Poster presentation: Texas Regional Chapter of the American College of Sports Medicine, Houston, TX. (1st place, Undergraduate Student Category)

Baek, K., A.A. Currado, M.R. Allen, and S.A. Bloomfield. (2003, February). Food restriction and hindlimb unloading: effects on serum leptin and bone. Poster presentation: Texas Regional Chapter of the American College of Sports Medicine, Houston, TX. (1st place, M.S. Student Category) Allen, M.R., S.A. Bloomfield, and C.L. Smith. (2002, February). Protective effects of

estrogenic compounds on unloaded bone in mature male rats. Poster presentation: Texas Regional Chapter of the American College of Sports Medicine, Georgetown, TX.

(1st place, Ph.D. student category) Allen, M.R. and S.A. Bloomfield. (2001, February). Maintenance of cancellous bone density

after 28 days of hindlimb unloading in skeletally mature female rat tibia. Slide presentation at the Texas Regional Chapter of the American College of Sports Medicine,

Fort Worth, TX. Hubal, M.J., C.P. Ingalls, M. Allen, J.C. Wenke, and S.A. Bloomfield. (2000, February).

Effects of eccentric exercise training on mouse skeletal muscle and bone. Poster presented at the Texas Regional Chapter of the American College of Sports Medicine,

College Station, TX. (1st place, M.S. Student Category) Allen, M.R., S.E. Gordon, B. Davis, M. Fiorotto, R. Schwartz, F.W. Booth, and S.A. Bloomfield. (2000, February). Skeletal muscle IGF-I overexpression increases bone

density but not mechanical strength and prevents hindlimb unloading bone loss in mature mouse tibia. Poster presentation: Annual Meeting of the Texas Regional Chapter of the American College of Sports Medicine, College Station, TX. (3rd place, Ph.D. student category).

Lorenz, E.P, H.A. Hogan, E.T. Dresser, J.A. Groves, and S.A. Bloomfield. (1999, February). Alterations in pQCT-derived bone geometry and volumetric density and in structura

properties of femoral neck in senescent rats. Research poster presentation at the Texas ACSM Chapter meeting, Clear Lake, TX.

Bloomfield, S.A. (1999, February). Exercise for optimal health in an aging population: barbells or treadmills? Oral slide presentation at the Texas ACSM Chapter meeting, Clear Lake, TX. (Invited)

Dresser, E.T., S.A. Bloomfield, and M.D. Delp. (1998, February). Age-induced alterations of bone tissue blood flow and vascular resistance in Fischer 344 rats. Research poster presentation at the Texas ACSM Chapter meeting, Arlington, TX.

Inman, C.L., and S.A. Bloomfield. (1996, February). In vivo mechanical loading attenuates

loss of bone strength with immobilization and calcium deficiency. Research poster presentation at the Texas ACSM Chapter meeting, Houston, TX. (1st place, M.S. Student Category)

Inman, C.L., and S.A. Bloomfield. (1995, February). Sources of variation for bone strain produced by external four-point bending of the rat tibia. Research poster presentation at the Texas ACSM Chapter meeting, Dallas, TX.

25Bloomfield, S.A. (1983, March). Exercise in chronic disease states. Oral presentation

at Grand Rounds, Gratiot Community Hospital, Alma, MI. (Invited) Bloomfield, S.A., M. Beattie, and C.V. Gisolfi. (1978, March). The role of dopamine in

exercise thermoregulation in the rat. Paper presented at the Annual Meeting of the Midwest Chapter American College of Sports Medicine, Boyne Mountain, MI.

SERVICE PRESENTATIONS

National Bloomfield, S.A. (June, 1995). Balancing career and family. Presented to Women’s

Breakfast, ACSM. Annual Meeting, Minneapolis, MN. State And Local Bloomfield, S.A. (May, 2001). Changes in the Human Body during Spaceflight. 4th grade

science classes, College Hills Elementary School, College Station, TX. Bloomfield, S.A. (May, 1998). Being a University Researcher in Physiology. Career Day,

Oakwood Intermediate School, College Station, TX. Bloomfield, S.A. and E.T. Dresser. (April, 1998). Bone Health, Spaceflight and the

College of Education. Forsythe-Heritage Forum, Texas A&M University, College Station, TX.

Bloomfield, S.A. (March, 1998). Rats, Humans, and Flying Machines. Science, Technology and YOUth Symposium, Texas A&M University, College Station, TX. Bloomfield, S.A. (March, 1997). Exercise and Health. Science-a-thon at Rock Prairie Bloomfield, S.A. and Gray, C.A. (November, 1983). Exercise science in undergraduate

education. Invited presentation at the Annual Meeting of Michigan AAPHERD, Traverse City, MI.

FUNDED PROPOSALS (Co-investigators who are my graduate student advisees in italics)

Federal/National-- Active NCC 9-58 NASA-NSBRI Role: PI 06/08 – 05/12 Total direct costs: $969,285 Maintaining musculoskeletal health in the Lunar environment

These studies will test the separate and combined effect of 1/6 g and radiation exposure modeling galactic cosmic radiation on bone and muscle outcomes in a murine model. Exercise countermeasures will be tested in the animals exposed to both environmental stressors.

NASA Human Research Program Role: Co-I (PI Harry Hogan, A&M Mech. Engineering) 07/08 - 06/11 Total direct costs: $796,187 Contributors to long-term recovery of bone strength following exposure to microgravity

These studies will track changes in bone mineral density, bone geometry, and organic matrix during recovery from single and multiple exposures to simulated microgravity, with

26the ultimate goal being to identify the most critical contributors to recovery of bone structural and material properties. (PI: H.A. Hogan, Texas A&M Univ.) National Space Biomedical Research Institute Role: Collaborator/Mentor 01/06 – 12/11 Total costs: $2,133,178 A Graduate Education Program Focusing on Space Life Sciences. (total costs). The goal of this Ph.D. training program is to develop scientists capable of solving three of the most critical problems in space life sciences: bone loss, muscle wasting, and cosmic

radiation. Program jointly co-sponsored by A&M Departments of Nutrition & Food Sciences, Nuclear Engineering, and Health & Kinesiology.

National Space Biomedical Research Institute Role: Associate Lead 05/08 – 04/12 Total costs: $120,000 Associate Lead for NSBRI Musculoskeletal Alterations Team These funds support costs associated with coordinating meetings of this team of investigators, compiling annual reports, representing the team’s interests with other professional societies and at NASA-JSC, and otherwise assisting the Team Lead. Department of Defense Role: PI 4/06-3/09 (No-cost extension to 4/10) Total direct costs: $710,176

Impact of graded energy restriction on bone health in exercising female rats: endocrine mechanisms. The objective of this project is to define the effect of several levels of negative energy balance on short- and long-term bone outcomes in a rodent model, whether these effects are attenuated in animals that are regularly exercising, and to define estrogen-dependent and -independent mechanisms for altered bone properties.

Federal/National-- Completed Bloomfield, S.A., Hogan, H.A., and Baldwin, K.M. (UC-Irvine). Increasing Efficiency of

Exercise Countermeasures for Bone Loss. National Space Biomedical Research Institute, Principal Investigator. 04/01/04- 3/31/08 $1,788,905 (total costs).

Baek, K. and S.A. Bloomfield (Co-PI). Nutrient restriction effects on bone in exercising females. American College of Sports Medicine Research Foundation. 7/05-6/06, $4,991.

Lupton, J. (PI). A Graduate Education Program Focusing on Space Life Sciences (Phase I). National Space Biomedical Research Institute, S.A. Bloomfield--Co-Investigator. 1/01/2005 - 12/31/2005. $116,026 (total costs).

Bloomfield, S.A., H.A.Hogan, C.L. Smith (Baylor College of Medicine). Bone and muscle

recovery from simulated microgravity. National Space Biomedical Research Institute, Principal Investigator. 10/00-9/03, $855,803 (total costs).

Smith, C.L. (Baylor COM), N.L.Weigel, (BCOM), and S.A. Bloomfield. Receptor counter-

measures to bone loss in microgravity. National Space Biomedical Research Institute, Co-Investigator. 10/00-9/03, $172,121 (total costs to Texas A&M).

27Bloomfield, S.A., M.D. Delp, L.J. Suva (Smith-Kline Beecham), and H.A. Hogan. Bone

blood flow during simulated microgravity: physiological and molecular mechanisms. National Space Biomedical Research Institute, Co-Principal Investigator. 10/97-9/00, $699,608.

Schultheis, L.W. (Johns Hopkins Univ.), Shapiro, J.R.(JHU), S.A. Bloomfield, N.S. Fedarko

(JHU), and D.J. McBride (JHU). The effects of partial mechanical loading and ibandro-nate on skeletal tissues in the adult rat hindquarter suspension model of microgravity. National Space Biomedical Research Institute, Co-Investigator. 10/97-9/00, $227,473 (total costs to Texas A&M)

O’Malley, B.W. (Baylor College of Medicine), C.L. Smith (BCOM), N.L. Weigel (BCOM), and

E.M. Brown (Harvard). [S.A. Bloomfield, PI on sub-contract] Novel receptor-based countermeasures to microgravity-induced bone loss. National Space Biomedical Research Institute, 3/00-9/00, $38,623. (Total costs to Texas A&M)

Bloomfield, S.A. Integrating molecular techniques into bone physiology research.

American Physiological Society Research Career Enhancement Award, Principal Investigator. 6/97-8/97, $4,000.

Bloomfield, S.A. Molecular mechanisms for the bone response to mechanical loading in an

in vivo model: preliminary studies. National Science Foundation, Principal Investigator 6/93-12/95, $18,000.

Bloomfield, S.A. Visiting Scholar Award (funding working visit to D.B. Kimmel laboratory at Creighton University's Osteoporosis Research Center), American College of Sports Medicine, Principal Investigator, 6/93-8/93, $3268.

State And Local Bloomfield, S.A. Effect of mechanical unloading on bone in mice lacking genes for eNOS.

TAMU College of Education Development Award, 3/02-12/02, $5860.

Bloomfield, S.A. Role of bone matrix proteins decorin and biglycan in skeletal adaptations to altered loading. TAMU College of Education Seed Grant Program, 2/00-1/01, $7398.

Bloomfield, S.A. Does aging attenuate the growth factor response of bone to mechanical

loading? TAMU Office of University Research Program to Enhance Scholarly and Creative Activities, Principal Investigator, 7/97-6/98, $7500.

Bloomfield, S.A. Localizing the growth factor response to mechanical loading in bone cells: in situ hybridization studies. TAMU Research and Graduate Studies Faculty Mini-Grant program, Principal Investigator, 11/95-12/95, $1500.

Bloomfield, S.A. A non-invasive, in vivo method for studying adaptation of bone to

mechanical loading: validation studies. TAMU Office of University Research Program to Enhance Scholarly and Creative Activities, Principal Investigator, 6/94-6/95, $7365.

Bloomfield, S.A. The efficacy of exercise induced by functional electrical stimulation in reversing neurogenic osteopenia in spinal cord injured individuals. The Ohio State

28University Graduate School Graduate Student Alumni Research Award, Principal Investigator, 5/89, $1500.

Bloomfield, S.A. The efficacy of functional electrical stimulation induced exercise and

weightbearing in minimizing bone loss subsequent to spinal cord injury. Sigma Xi Grant-in-Aid of Research, Co-Investigator, 3/89, $600.

Bloomfield, S.A. Effects of exercise training and dobutamine on bone loss incurred during

hindlimb unweighting in rats. Oberlin College Alumni Fellowship Award, Principal Investigator, 4/87, $1250.

COMMUNITY AND CIVIC ACTIVITIES U.S. Masters Swimming, regular competitor: SC National Championships (2004, 2008); LC

National Championships (1999, 2007); Pan Pacific Meet (Indianapolis, 1990); FINA Masters World Championships (Indianapolis, 1992; Palo Alto, CA, 2006).

Unitarian Universalist Fellowship of Brazos Valley: Program Committee (1994-95), Nominating Committee (1996, 1998), Full-Time Ministry Committee (1996), Sunday School teacher (1996-2002, 2004-2005), Diversity Committee Co-chair (1997-2000), Board of Trustees (2003-2004); Ministerial Search Committee (2006-2007); Committee on Ministry (2007-present); Mission/Vision Team (2008- 2009).

Volunteer coach, Buckeye Masters Swim Club (1987-1989) Instructor, AHA Basic Cardiac Life Support (CPR) (1979-1989)

Last updated: 8/13/09