Supplemental Figure 1

10
Supplemental Figure 1

description

Supplemental Figure 1. Supplemental Figure 2. Supplemental Figure 3. A. B. C. D. Supplemental Figure 4. A. B. 231. 231. C. D. 231-Ecad. 231-Ecad. E. F. 231-shEcad. 231-shEcad. G. H. DU-145. DU-145. Supplemental Figure 5. Supplemental Figure 6. Supplemental Figure 7. A. - PowerPoint PPT Presentation

Transcript of Supplemental Figure 1

Page 1: Supplemental Figure 1

Supplemental Figure 1

Page 2: Supplemental Figure 1

Supplemental Figure 2

Page 3: Supplemental Figure 1

0

20

40

60

80

100

120

140

0 0.01 0.1 1 10 100Dose Taxol (uM)

% Cell Survival

231231-EcadMCF7MCF7-shEcad

0

20

40

60

80

100

120

140

0 0.01 0.1 1 10 100Dose 5-FU (ug/ml)

% Cell Survival

231231-EcadMCF7MCF7-shEcad

020406080

100120140160

0 0.01 0.1 1 100 1000Dose Doxorubicin (nM)

% Cell Survival

231231-EcadMCF7MCF7-shEcad

020406080

100120140160

0 0.01 0.1 1 100 1000Dose Cyclophosphamide (uM)

% Cell Survival

231231-EcadMCF7MCF7-shEcad

Supplemental Figure 3

A B

C D

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Supplemental Figure 4

HG

A B231 231

C D231-Ecad 231-Ecad

FE 231-shEcad 231-shEcad

DU-145 DU-145

Page 5: Supplemental Figure 1

Supplemental Figure 5

Page 6: Supplemental Figure 1

Supplemental Figure 6

Page 7: Supplemental Figure 1

Supplemental Figure 7

A

B

**

*

* *

Page 8: Supplemental Figure 1

Supplemental Figure 8

ASt

auro

spor

ine

Cam

ptot

heci

n

10nM

1000

nM10

μM10

0μM

231 231-Ecad 231-shEcadun

trea

ted

B

* *

* *

* *

untreated 1000nMStaurosporine10nM 100μM

Camptothecin10 μM

Page 9: Supplemental Figure 1

Supplemental Figure 9

DU-145

d1 d6 d1 d6 d1 d6trans

DU-145 + human heps

direct

DU-145 only

d1 d6 d1 d6 d1 d6

DU-145 + fibro

Fibro only

A

B

C

D

DU-145 only

d1 d6 d1 d6 d1 d6

DU-145 + hu heps

Hu heps only

DU-145

d1 d6 d1 d6 d1 d6siEcad

DU-145 + human heps

siControl

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Supplemental Figure 10