Superficial Mycoses11

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    Superficial MycosesSuperficial Mycoses))Dermatophytes))Dermatophytes

    )Skin Plants()Skin Plants(

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    SUPERFICIAL MYCOSESSUPERFICIAL MYCOSES

    The superficial mycoses are usuallyThe superficial mycoses are usuallyconfined to the outermost layer of skin,confined to the outermost layer of skin,hair and do not invade living tissues.hair and do not invade living tissues.

    http://upload.wikimedia.org/wikipedia/commons/3/34/Skin.jpg
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    SUPERFICIAL MYCOSESSUPERFICIAL MYCOSES

    Pityriasis versicolorPityriasis versicolorTinea nigraTinea nigra

    Black piedraBlack piedraWhite piedraWhite piedraKeratomycosisKeratomycosis

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    PITYRIASIS VERSICOLORPITYRIASIS VERSICOLOR

    (Tinea versicolor)(Tinea versicolor)Superficial chronic infection ofSuperficial chronic infection of

    Stratum corneumStratum corneum Etio:Etio: Malassezia furfurMalassezia furfur

    (Pityrosporum orbiculare)(Pityrosporum orbiculare)

    (Lipophilic yeast)(Lipophilic yeast) Clinical findings:Clinical findings: HyperpigmentedHyperpigmented

    or depigmented maculae on chest,or depigmented maculae on chest,

    back, arms, abdomenback, arms, abdomen

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    - Characterized by a blotchy discoloration of skinCharacterized by a blotchy discoloration of skinwhich may itch.which may itch.

    - Up to 25% of the general population may have this lesion at- Up to 25% of the general population may have this lesion at

    any one time.any one time.- Diagnosis is usually possible by direct microscopic- Diagnosis is usually possible by direct microscopic

    examination of KOH-treated skin scrapings which show aexamination of KOH-treated skin scrapings which show atypical aspect of mycelia and spores described as "spaghettitypical aspect of mycelia and spores described as "spaghettiand meatballs.and meatballs.

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    PITYRIASIS VERSICOLORPITYRIASIS VERSICOLOR

    Treatm.:Treatm.: Topical seleniumTopical seleniumsulfidesulfide

    Oral ketaconazoleOral ketaconazoleOral itraconazoleOral itraconazole

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    TINEA NIGRATINEA NIGRA

    Superficial chronic infection ofSuperficial chronic infection ofStratum corneumStratum corneum

    Etio:Etio: HortaeHortae(Exophiala) werneckii(Exophiala) werneckii(pigmented)(pigmented)

    Frequent in tropical areasFrequent in tropical areas Clinical findings:Clinical findings: Brownish maculaeBrownish maculae

    on palms, fingers, faceon palms, fingers, face

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    TINEA NIGRATINEA NIGRA

    Micr.:Micr.: Septate hyphae and yeastSeptate hyphae and yeastcells (brown in color)cells (brown in color) Culture:Culture: Black coloniesBlack colonies

    Treatm.:Treatm.: Topical salicylic acid,Topical salicylic acid,tincture of iodinetincture of iodine

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    BLACK PIEDRABLACK PIEDRA

    Fungal infection of the scalp hairFungal infection of the scalp hair Etio:Etio:Piedraia hortaePiedraia hortae

    Frequent in tropical areasFrequent in tropical areas Clinical findings:Clinical findings: Discrete, hard,Discrete, hard,

    dark brown to black nodules ondark brown to black nodules on

    the hairthe hair

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    BLACK PIEDRABLACK PIEDRA

    Micr.Micr. Septate pigmented hyphae,Septate pigmented hyphae,

    and asci; unicellular and fusiformand asci; unicellular and fusiformascospores with polar filament(s)ascospores with polar filament(s) Culture:Culture: Brown to black coloniesBrown to black colonies

    Treatm.:Treatm.: Topical salicylic acid,Topical salicylic acid,azol cremesazol cremes

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    WHITE PIEDRAWHITE PIEDRA

    Fungal infection of facial, axillaryFungal infection of facial, axillaryor genital hairor genital hair

    Etio:Etio:TrichosporonTrichosporon(yeast)(yeast) Frequent in tropical andFrequent in tropical and

    temperate zonestemperate zones

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    WHITE PIEDRAWHITE PIEDRA

    Clinical findings:Clinical findings: Soft, white toSoft, white toyellowish nodules looselyyellowish nodules loosely

    attached to the hairattached to the hair

    Micr.:Micr.: Intertwined septateIntertwined septate

    hyphae, blasto- and arthroconidiahyphae, blasto- and arthroconidia

    Culture:Culture: Soft, creamy coloniesSoft, creamy colonies

    Treatm.:Treatm.: Shaving, azolesShaving, azoles

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    KERATOMYCOSISKERATOMYCOSIS

    (=Mycotic keratitis)(=Mycotic keratitis) Posttraumatic / postsurgicalPosttraumatic / postsurgical

    corneal inf.corneal inf. Etio:Etio: Saprophytic fungiSaprophytic fungi

    ((AspergillusAspergillus,, Fusarium,Fusarium,

    Alternaria, Candida), HistoplasmaAlternaria, Candida), Histoplasmacapsulatumcapsulatum Clinical findings:Clinical findings: Corneal ulcerCorneal ulcer

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    KERATOMYCOSISKERATOMYCOSIS

    Micr.:Micr.:Hyphae in cornealHyphae in cornealscrapingsscrapings

    Treatm.:Treatm.: Surgery (keratoplasty)Surgery (keratoplasty)Topical pimaricinTopical pimaricin

    NystatinNystatinAmphotericin BAmphotericin B