Superficial Mycoses11
Transcript of Superficial Mycoses11
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Superficial MycosesSuperficial Mycoses))Dermatophytes))Dermatophytes
)Skin Plants()Skin Plants(
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SUPERFICIAL MYCOSESSUPERFICIAL MYCOSES
The superficial mycoses are usuallyThe superficial mycoses are usuallyconfined to the outermost layer of skin,confined to the outermost layer of skin,hair and do not invade living tissues.hair and do not invade living tissues.
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SUPERFICIAL MYCOSESSUPERFICIAL MYCOSES
Pityriasis versicolorPityriasis versicolorTinea nigraTinea nigra
Black piedraBlack piedraWhite piedraWhite piedraKeratomycosisKeratomycosis
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PITYRIASIS VERSICOLORPITYRIASIS VERSICOLOR
(Tinea versicolor)(Tinea versicolor)Superficial chronic infection ofSuperficial chronic infection of
Stratum corneumStratum corneum Etio:Etio: Malassezia furfurMalassezia furfur
(Pityrosporum orbiculare)(Pityrosporum orbiculare)
(Lipophilic yeast)(Lipophilic yeast) Clinical findings:Clinical findings: HyperpigmentedHyperpigmented
or depigmented maculae on chest,or depigmented maculae on chest,
back, arms, abdomenback, arms, abdomen
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- Characterized by a blotchy discoloration of skinCharacterized by a blotchy discoloration of skinwhich may itch.which may itch.
- Up to 25% of the general population may have this lesion at- Up to 25% of the general population may have this lesion at
any one time.any one time.- Diagnosis is usually possible by direct microscopic- Diagnosis is usually possible by direct microscopic
examination of KOH-treated skin scrapings which show aexamination of KOH-treated skin scrapings which show atypical aspect of mycelia and spores described as "spaghettitypical aspect of mycelia and spores described as "spaghettiand meatballs.and meatballs.
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PITYRIASIS VERSICOLORPITYRIASIS VERSICOLOR
Treatm.:Treatm.: Topical seleniumTopical seleniumsulfidesulfide
Oral ketaconazoleOral ketaconazoleOral itraconazoleOral itraconazole
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TINEA NIGRATINEA NIGRA
Superficial chronic infection ofSuperficial chronic infection ofStratum corneumStratum corneum
Etio:Etio: HortaeHortae(Exophiala) werneckii(Exophiala) werneckii(pigmented)(pigmented)
Frequent in tropical areasFrequent in tropical areas Clinical findings:Clinical findings: Brownish maculaeBrownish maculae
on palms, fingers, faceon palms, fingers, face
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TINEA NIGRATINEA NIGRA
Micr.:Micr.: Septate hyphae and yeastSeptate hyphae and yeastcells (brown in color)cells (brown in color) Culture:Culture: Black coloniesBlack colonies
Treatm.:Treatm.: Topical salicylic acid,Topical salicylic acid,tincture of iodinetincture of iodine
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BLACK PIEDRABLACK PIEDRA
Fungal infection of the scalp hairFungal infection of the scalp hair Etio:Etio:Piedraia hortaePiedraia hortae
Frequent in tropical areasFrequent in tropical areas Clinical findings:Clinical findings: Discrete, hard,Discrete, hard,
dark brown to black nodules ondark brown to black nodules on
the hairthe hair
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BLACK PIEDRABLACK PIEDRA
Micr.Micr. Septate pigmented hyphae,Septate pigmented hyphae,
and asci; unicellular and fusiformand asci; unicellular and fusiformascospores with polar filament(s)ascospores with polar filament(s) Culture:Culture: Brown to black coloniesBrown to black colonies
Treatm.:Treatm.: Topical salicylic acid,Topical salicylic acid,azol cremesazol cremes
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WHITE PIEDRAWHITE PIEDRA
Fungal infection of facial, axillaryFungal infection of facial, axillaryor genital hairor genital hair
Etio:Etio:TrichosporonTrichosporon(yeast)(yeast) Frequent in tropical andFrequent in tropical and
temperate zonestemperate zones
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WHITE PIEDRAWHITE PIEDRA
Clinical findings:Clinical findings: Soft, white toSoft, white toyellowish nodules looselyyellowish nodules loosely
attached to the hairattached to the hair
Micr.:Micr.: Intertwined septateIntertwined septate
hyphae, blasto- and arthroconidiahyphae, blasto- and arthroconidia
Culture:Culture: Soft, creamy coloniesSoft, creamy colonies
Treatm.:Treatm.: Shaving, azolesShaving, azoles
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KERATOMYCOSISKERATOMYCOSIS
(=Mycotic keratitis)(=Mycotic keratitis) Posttraumatic / postsurgicalPosttraumatic / postsurgical
corneal inf.corneal inf. Etio:Etio: Saprophytic fungiSaprophytic fungi
((AspergillusAspergillus,, Fusarium,Fusarium,
Alternaria, Candida), HistoplasmaAlternaria, Candida), Histoplasmacapsulatumcapsulatum Clinical findings:Clinical findings: Corneal ulcerCorneal ulcer
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KERATOMYCOSISKERATOMYCOSIS
Micr.:Micr.:Hyphae in cornealHyphae in cornealscrapingsscrapings
Treatm.:Treatm.: Surgery (keratoplasty)Surgery (keratoplasty)Topical pimaricinTopical pimaricin
NystatinNystatinAmphotericin BAmphotericin B