SUCCESS STORY CAMAG INNOSUISSE (CTI)de7d671b-098b... · CAMAG –60 years dedicated to...
Transcript of SUCCESS STORY CAMAG INNOSUISSE (CTI)de7d671b-098b... · CAMAG –60 years dedicated to...
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© CAMAG 2018
SUCCESS STORY CAMAG – INNOSUISSE (CTI)Markus Wyss, Ph.D.
CEO, CAMAG
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CAMAG – 60 years dedicated to chromatography
CAMAG was founded 1958 in Muttenz, Switzerland
Niche business: Production of Aluminum Oxide for chromatography
World-market leader: Instruments and software for High-Performance Thin-Layer
Chromatography (HPTLC), an analytical method
Launched: Automated high-throughput elution instrument (DBS-MS 500) to analyze dried
blood spots in clinical diagnostics
Innosuisse Presentation2
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CAMAG – Global Presence
CAMAG Muttenz (Headquarters): provides
direct sales & services within Switzerland
and to countries having no appointed
distributor
Two subsidiaries:
CAMAG Berlin for Germany, The Netherlands,
Belgium & Austria
CAMAG Scientific Inc. for North America
More than 70 distributors serving more than 90
countries worldwide
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TLC in all its versions
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Instrumental TLC
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Application
Detection
Documentation
Development
The Plate
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Comparison of multiple Samples: Curcuma
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0.1 g/mL methanol, ultrasonication for 10 min; centrifugation; toluene - acetic acid (4:1)
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Limit-Test for THC-free Cannabis samples
Innosuisse Presentation7
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A breakout for CAMAG: Dried Blood Spot Analysis
Innosuisse Presentation8
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INNOSUISSE (CTI) Projects with CAMAG
2010: DBS-MS direct blood spot analysis system for Mass Spectrometer
Prof. Dr. Agathe Koller-Hodac
2012: DMS/DBS-MS: Extension of the capabilities to suit the hospital market for therapeutic
drug monitoring Prof. Dr. Agathe Koller-Hodac
& PD Dr. Manuel Haschke
2014: Automated extraction of dired blood for the newborn screening
Prof. Dr. Götz Schlotterbeck
PD Dr. Ralph Fingerhut
Innosuisse Presentation9
Institut für Labortechnologie
Hochschule für Life Sciences
Institut für Labortechnologie
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DBS-MS 500 Dried Blood Spot Analysis for Diagnostics
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Robotics
Optical card
recognition
Software
Extraction
Internal
standard
application
Blood spotting
Cleaning
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DBS-LC-MS/MS System used for Newborn-Screening, Forensic and Therapeutic Drug Monitoring
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Automated High-Performance Thin-Layer Chromatography (HPTLC) for Routine Analysis
HPTLC format and layer (20 x 10 cm, 200 µm layer thickness)
Proper instruments for all steps (including software)
Standardized methodology
Validated methods
results in
Reproducible results
plate to plate, day to day, lab to lab …
cGMP compliance
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New Instruments in Development
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INNOSUISSE (CTI) Projects with CAMAG on HPTLC
2014: Next generation High-Performance Thin-Layer Chromatography (HPTLC)
Prof. Dr. Agathe Koller- Hodac
2017: Next generation High-Performance Thin-Layer Chromatography: Integration of
additional functionality in specific modules to complete the Next Generation concept.
Prof. Dr. Agathe Koller- Hodac
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Institut für Labortechnologie
Institut für Labortechnologie
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Benefit for the Research Partners to apply for a INNOSUISSE (CTI) Project
Applied research - to be commercialized immediately
Generation of IP rights (outside the field of interest of the industrial partner)
Education of the next generation of scientists
Access to commercially relevant research topics
….but not optimal for basic research projects
Innosuisse Presentation15
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Benefit for Industry Partner to apply for a INNOSUISSE (CTI) Project
Reduce time to market
Be able to choose from cutting-edge technology - without permanent employment
Generate IP in the field of interest – competitive advantage
Focused on Switzerland, all handled within the Swiss administration
Mentor to help file the request - experts to challenge it
Optimal for SME’s
….but industrial partner has to be ready to invest into the future (> 50% own investment)
Innosuisse Presentation16
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© CAMAG 2018
Additional Information: www.camag.com
or during the follow-up in our discussion group tonight