8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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[}xuk}uxe Hg{em Me{aol glm Al.[acakb Nbcekucgx

Mbkdalo Glgcq{a{ bi [bne Lbyec Helpanamgpbce{

[H NaxpgIG77.XHA.::=

7{} {ne{}ex N[ Habalibxng}ak{

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Anzxe{{abl

Al }fe zxe{el} alye{}aog}abl lbyec {uh{}a}u}emhelpanamgpbce{ gxe me{aolem glm mbkdem al }b gk}aye{a}e bi Kqkcbbvqoelg{e AA, Caoglm{ gxe me{aolem hg{em

bl }fe {}xuk}uxe bi xekez}bx# KBV.AA glm wecc dlbwlL[GAM Kecekbvah,Iux}fex Al. [acakb mbkdalo glgcq{a{ bime{aolem caoglm{ gxe zexibxnem }b zxemak} halmalo nbme#bxael}g}abl{ glm giiala}q,Caoglm{ lunhex ;6# ;1# =:# =7#=8# =; glm == gxe fgyalo ce{{ halmalo elexoq al d`"nbceglm {gam }b zb{{e{{ nbxe giiala}q ibx xekez}bx }fgl b}fexnbcekuce{ glm kecekbvah,

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Helpanamgpbce

Gl}aalicgnng}bxqglgcoe{ak

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Me{aol bi helpanamgpbce hg{em {ecek}ayeKBV.AA alfaha}bx{

Kqkcbbvqoelg{e{

zxb{}gocglmal{ }fxbnhbvgle

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Kqkcbbvqoelg{e{

}wb ngal a{bibxn{KBV.70{ql}fe{a{ bi zxb{}gocglmal glm}fxbnhbvgle al og{}xb.al}e{}algc }xgk} glm

hcbbm zcg}ece}{KBV.80alicgnng}bxq kecc{ glm al }fe kel}xgclexybu{ {q{}en

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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KBV.8 alfaha}bx{

cgxoex gk}aye {a}e bi KBV.8 wfakfzbcgx fqmxbzfacak {ame zbkde} }fg} ibxn{hekgu{e bi {uh{}a}u}abl bi Ace58;# Fa{57;#

glm Ace=;= al KBV.7hq Ygc 58;# Gxo 57;# glm Ygc=;= al KBV.8

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Caoglm {}xuk}uxe zxezgxg}abl

Kfen Mxgw Uc}xg# kfenakgc {}xuk}uxe mxgwalo{}glmgxm# Kgnhxamoe [bi} Kbxzbxg}abl# U[G, Yex{abl.6,: Gzxac 8;# 8::;

zxezgxg}abl bx mxgwalo bi caoglm nbcekuce{

kbxxek}abl }b }fe {}xuk}uxe{Oelexg}e ygxag}abl{ bl {}xuk}uxebz}anape }fe {}xuk}uxe

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Zxb}eal {}xuk}uxe zxezgxg}abl

]fe ZMH kbnzcev {}xuk}uxekbxxek}em u{alo0nbcekucgx nbmecaloelyaxblnel} Nbcekucgx Me{aol [ua}

]fe zxb}eal a{ gc{b bz}anapem0 u{alo NexkdNbcekucgx Ibxke Iaecm

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Nbcekucgx mbkdalo

{kbxalo iulk}abl{#halmalo giiala}ae{bxael}g}abl bi }fe{e kbnzbulm{ g} }fe

gk}aye {a}e

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Iao, 7, Me{aol bi lbyec KBV. AA alfaha}bx hg{em bl [uczfblgname

Kbvah{

G, Me{aolem nbcekuce al }b gk}aye {a}eH, [uczfblgname kbvah# kecekbvah al gk}aye {a}e

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Iao, 8,g Nbcekuce lb, ;1 al }b }fe gk}aye {a}e bi

KBV.AA {fbwalo kfgxoe al}exgk}abl{ he}weel

mbuhce hblm bi caoglm glm GXO g} ;?9H

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Iao,8,h Nbcekuce =: al gk}aye {a}e a} fg{ mbkd {kbxe

bi .7:,=9# {fbwalo Kfgxoe al}exgk}abl{,

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Iao, 8,k Nbcekuce lb,;1 al }fe gk}aye {a}e {fbwalo

kgya}q yglmex.wgcc{ al}exgk}abl{,

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Iao, 8,m, Nbcekuce lb, ;6 al gk}aye {a}e bi }fe

A} fg{ {kbxe bi .7=,8;

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Iao, 8,e Nbcekuce lb, == al gk}aye {a}e {fbwalo kfgxoe

al}exgk}abl{ he}weel he}weel fqmxbvqc oxbuz glm GXO

;?9,

8/3/2019 Structure Based Design and In-Silico MolecularDocking Analysis of Some Novel Benzimidazoles

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Kblkcu{abl

yglmex.wgcc{# fqmxbzfbhak glm kfgxoe al}exgk}abl{ gxe

xe{zbl{ahce ibx ibxnalo }fe {}ghce kbnzbulm bi }fe

caoglm{ wa}f xekez}bx, e{}ex bi hucdq gkam{ iulk}abl g} 8 zb{a}abl bi

helpanamgpbce{ gxe fgyalo ce{{ giiala}q ibx }fe

xekez}bx,

gckbfbcak wa}f ce{{ hucdq iulk}abl ;6.== gxe {gam }b fgyenbxe giiala}q ibx KBV.AA glm kgl he u{em g{ glgcoe{ak

glm gl}a.alicgnng}bxq goel}{ gi}ex {ql}fe{a{,

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