Strabismus Dr HAN Wei The 1 st Affiliated Hospital, Medical College, Zhejiang University.
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Transcript of Strabismus Dr HAN Wei The 1 st Affiliated Hospital, Medical College, Zhejiang University.
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Strabismus
Dr HAN WeiThe 1st Affiliated Hospital, Medical College,
Zhejiang University
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Basic knowledge of ocular motility
Extraocular muscles
Not playing role in vision procedure directly, b
ut critically important for eyeball motility and b
inocular vision function.
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Anatomy of extraocular muscles
Six extra-ocular muscles for the human eye. Namely: Medial rectus m. Lateral rectus m. Superior rectus m. Inferior rectus m. Superior oblique m. Inferior oblique m.
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Insertion positions of four rectus m.
MR: Medial rectus m. LR: Lateral rectus m. SR: Superior rectus m. IR: Inferior rectus m.
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Nerve innervation for extraocular m.
III cranial n.III cranial n. Medial rectus m. Superior rectus m. Inferior rectus m. Inferior oblique m.
IV (Trochlea) cranial n.IV (Trochlea) cranial n. Superior oblique m.
VI (Abduction) cranial n.VI (Abduction) cranial n. Lateral rectus m.
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Basic motility function of the eye ball
Elevation and depression (A, B)Elevation and depression (A, B)
Adduction and abduction (C, D)Adduction and abduction (C, D)
Intorsion and extorsion (E, F) Intorsion and extorsion (E, F)
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Motility functions of right eye’s extraocular muscle
Inferior oblique m. Extorsion Elevation Adduction
Superior rectus m. Elevation Intorsion Adduction
Inferior rectus m. Depression Adduction Extorsion
Superior oblique m. Intorsion Depression Abduction
Lateral rectus m. Abduction
Medial rectus m. Adduction
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Terminology of extra-ocular muscle regarding their physiological functions
Antagonist m.:Antagonist m.: the muscle that counteracts the agonist (or the prime mover); lengthening when the agonist muscle contracts. e.g., medial rectus and lateral rectus m..
Yoke m. : Yoke m. : The contra-laterally paired extra-ocular muscles of two fellow eyes that
work synergistically to direct the gaze in a given direction. Example: in directing the gaze to the right, the right lateral rectus and
left medial rectus operate together as yoke muscles.
Synergist m.: Synergist m.: The muscles moving one single eye ball in the same direction as the
prime moving muscle. e.g., inferior oblique m. is the synergist of superior rectus m. when the
eye turns upward.
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Nervous innervation laws
Sherrington law:
A muscle will relax when its antagonist muscle
(e.g., lateral and medial m.) is activated.
Hering law:
The yoke m. are innervated equally by nervous
system in eye movement.
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Eye position for examination
Primary position:
With condition in which head being put vertically and
straightforward and two eyes looking straightforward.
Secondary position:
The two eyes being in adduction or abduction or elevation or
depression position.
Tertiary position:
Two eyes gazing in oblique directions (up or downward).
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Left superior rectus m. Right inferior oblique m.Right superior rectus m.
Right medial rectus m.Left lateral rectus m.
Left inferior rectus m.Right inferior rectus m.
Right superior oblique m.
Right Superior rectus m.Left inferior oblique m.Left superior rectus m.
Left medial rectus m.Right lateral rectus m.
Right inferior rectus m.Left superior oblique m.Left inferior rectus m.
Right Superior rectus m.Left Superior rectus m.
Right Inferior rectus m.Left Inferior rectus m.
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Definitions
Strabismus: A condition in which the eyes are not properly aligned with
each other, i.e., manifest deviation of the eyes exist.
Heterophoria: A condition in which the visual axes of two eyes fail to rem
ain parallel after elimination of visual fusional stimuli. e.g, covering one eyee.g, covering one eye
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Classification Based on concomitancy
Concomitant: Angle of squint is the same in all directions of gaze.
Exotropia Esotropia
Inconcomitant: Angle differs in different directions of gaze.
Special types: e.g., Duane syndrome Based on etiology
Functional Paralytic (secondary to traumatic or pathological lesions)
Based on constancy Constant
Single eye deviation Alternative deviation
Intermittent
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Examination and diagnosis
Disease and familial historyDisease and familial history Onset ageOnset age Visual acuityVisual acuity RefractionRefraction Strabismus typeStrabismus type Compensative head positionCompensative head position Test for strabismus*Test for strabismus*
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Epicanthal fold – should be ruled out in child patients
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Simulated esotropiaSimulated esotropia
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Cover test and uncover testCover test and uncover test Alternative cover testAlternative cover test
Unilateral gaze (A) or alternative gaze (B)
Strabismus test (1)
A
B
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Strabismus test (2)
Corneal reflex testCorneal reflex test Simple, easy methodSimple, easy method Broadly applied in clinicBroadly applied in clinic
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Strabismus test (2)
Other methodsOther methods Prism and cover tPrism and cover t
estest Perimeter arc testPerimeter arc test Maddox rod testMaddox rod test Synoptophore testSynoptophore test
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Concomitant strabismus
Accommodative Complete accommodative Partially accommodative
Non-accommodative First deviation angle = Secondary deviation angle
First deviation angle: When the normal eye gazing target, the strabismus angle of the deviated eye.
Second deviation angle: When deviated eye gazing target, the strabismus angle of the normal eye.
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Concomitant esotropia
Most commonly seen type, closely assMost commonly seen type, closely associated with accommodation function.ociated with accommodation function.
First angle = Second angleFirst angle = Second angle Usually no diplopiaUsually no diplopia Normal ocular motilityNormal ocular motility Intermittent in incipient stage and turIntermittent in incipient stage and tur
n to be constant gradually. n to be constant gradually.
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Treatment Treatment
Spectacle correction for ametroSpectacle correction for ametropiapia
Treat amblyopiaTreat amblyopia Eye position trainingEye position training SurgerySurgery
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An example of concomitant esotropia
After operation, the two eyes’ position is corrected to be normal. (Lower figure)
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An example of partially accommodative concomitant esotropia
With spectacle, squint was partially corrected, but still existed. (lower figure)
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Concomitant exotropia
Associated with:Associated with: Central nervous biocular balancing function, Central nervous biocular balancing function, Imbalance of accommodation and convergence,Imbalance of accommodation and convergence, AnisometropiaAnisometropia Visual impairment in one eyeVisual impairment in one eye
Intermittent early stage to constant stage. Intermittent early stage to constant stage. Treatment:Treatment:
Ametropia correctionAmetropia correction Prism spectaclePrism spectacle SurgerySurgery
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An example of concomitant exotropia treated by surgery
Deviation was correctly after surgery. (Figure left)
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An example of concomitant exotropia due to visual impairment in left eye
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Nonconcomitant strabismus
Usually paralytic secondary to: Embryo development anomalies Trauma Inflammation Hypertension and hemorraghe & ischemia Tumor Metabolism disorder like diabetes, thyroidism, etc
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Symptoms
Diplopia Diplopia Compensation head positionCompensation head position Deviation of affected eyeDeviation of affected eye First angle First angle < < second anglesecond angle Compromise of ocular motilityCompromise of ocular motility
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Hess screen test
Shift of the square denotes the muscle Shift of the square denotes the muscle being paralytic.being paralytic.
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Compensation head position in paralysis of the right eye’s lateral rectus muscle
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An example of paralytic esotropia
Lateral rectus m. of right eye paralysis. Note the 1st angle (figure right) is less than second angle (figure left)
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An example of paralytic vertical strabismus of right inferior rectus m.
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Treatment Primary diseases treatmentPrimary diseases treatment Drug Drug
Vit B1, B12, ATPVit B1, B12, ATP SteroidSteroid AntibioticsAntibiotics Botulinum A injection to relief the muscle spasmBotulinum A injection to relief the muscle spasm PrismPrism
SurgerySurgery Usually 6 months after onset, with deviation being stable.Usually 6 months after onset, with deviation being stable.
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Differentiation of paralytic and concomittent strabismus
Paralytic Concomittent
Onset SuddenlySuddenly GraduallyGradually
Eye motility Compromised in affected Compromised in affected m. movement directionm. movement direction
NormalNormal
Deviation angle 22ndnd angle > 1 angle > 1stst angle angle EqualEqual
Diplopia YesYes NoNo
Compensative head position
YesYes NoNo
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Amblyopia
Definition of amblyopia: otherwise known as lazy ey
e, is a disorder of the visual system that is characterize
d by poor or indistinct vision in an eye that is otherwis
e physically normal.
It has been estimated to affect 1–5% of the population.
Etiology: The nerve pathway from one eye to the brain
does not develop during childhood or the abnormal ey
e sends a blurred image to the brain.
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Category of etiology
Strabismus Strabismus (Most common type, due to crossing eye)(Most common type, due to crossing eye)
Anisometropia Anisometropia (Imbalance of visual input)(Imbalance of visual input)
Ametropia Ametropia (Double eye onset)(Double eye onset)
Form deprivation Form deprivation (Refractive media opacity)(Refractive media opacity)
Others Others (Pathological lesions)(Pathological lesions)
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Symptoms
Vision acuity lossVision acuity loss Mild:Mild: 0.6-0.80.6-0.8 Moderate:Moderate: 0.2-0.50.2-0.5 Severe: Severe: less than less than
0.10.1 Abnormal fixationAbnormal fixation Crowding phenomenonCrowding phenomenon
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Treatment (1)Treatment (1)
Early treatment. Early treatment. As early as possible. Critically As early as possible. Critically
important!important! Treatment effect is poor after 9 years Treatment effect is poor after 9 years
old.old.
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Ametropia correction: spectacle even LASIK, surgery fAmetropia correction: spectacle even LASIK, surgery for congenital cataract.or congenital cataract.
Occlusion therapyOcclusion therapy Occluding normal eye, allowing amblyopic eye tOccluding normal eye, allowing amblyopic eye t
o develop o develop Red light therapyRed light therapy
Stimulating the macular function developmentStimulating the macular function development After image therapyAfter image therapy Depression therapyDepression therapy
Using atropine or over- or under-correction lensUsing atropine or over- or under-correction lens Synoptophore therapySynoptophore therapy Drug (L-Dopa)Drug (L-Dopa)
Treatment (2)
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Nystagmus
A condition of involuntary rhythmically oscillation of the globe. According to the rhythm, it is divided into two sorts:
jerky and pendular.
Physiological and pathological Category:
Perpetual Opticokinetic Labyrinthine Environmental
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Binocular vision
Normal human’s vision is the matter of the co-Normal human’s vision is the matter of the co-ordination of the two eyes. ordination of the two eyes.
The eyes must be capable of aligning themselves in The eyes must be capable of aligning themselves in such a manner: the retinal images of a fixated target such a manner: the retinal images of a fixated target can easily be placed and maintained on the foveae of can easily be placed and maintained on the foveae of the two eyes. the two eyes.
Normal binocular vision is established in about 5-6 Normal binocular vision is established in about 5-6 years.years.
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Binocular vision
Condition of the normal binocular Condition of the normal binocular vision : vision : (1) in good focus;(1) in good focus; (2) similar image size (within 5% (2) similar image size (within 5%
disparity); disparity); (3) similar image shape;(3) similar image shape; (4) normal eyes’ motility; (4) normal eyes’ motility; (5) fusion ability and area; (5) fusion ability and area; (6) normal neural pathways.(6) normal neural pathways.
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Grade of binocular visionGrade of binocular vision Simultaneous perception
Ability to simultaneously percept the retinal image of the two eyes
Fusion Images formed on the retina o
f the two eyes are combined into a single percept.
Stereopsis Highest grade of binocular vis
ion. Perception of depth and distance.
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Normal binocular vision Sensory aspectsSensory aspects
Corresponding retinal pointsCorresponding retinal points Panum fusional areasPanum fusional areas HoropterHoropter Physiological diplopiaPhysiological diplopia
Motor aspectsMotor aspects Conjugate movementConjugate movement
Saccadic movementSaccadic movement Following movementFollowing movement
Disconjugate movement Disconjugate movement ConvergenceConvergence DivergenceDivergence Motor fusionMotor fusion
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Abnormal binocular vision
Diplopia Diplopia pathologicalpathological
ConfusionConfusion misalignment of the two eyes in paralytic strabismusmisalignment of the two eyes in paralytic strabismus
SuppressionSuppression amblyopiaamblyopia
Abnormal retinal correspondenceAbnormal retinal correspondence strabismusstrabismus
Eccentric fixationEccentric fixation amblyopiaamblyopia
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Low vision Definition of low vision (WHO 1992)
Best corrected visual acuity <0.3, Semi-visual field narrower than 10 degree
Treatment Etiological diseases if viable
Visual aid instruments Telescope Magnifier Electronic apparatus like CCTV, computer display
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Low vision aid products
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QuestionsQuestions
State refractive components of the eye’s optical system.
The category of myopia and the clinical management?
The classification of the concomittent strabismus and the clinical management?