Steroidal Hormones
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Transcript of Steroidal Hormones
STEROIDS
A steroid hormone (abbreviated as sterone) is a steroid that acts as ahormone. Steroid hormones can be grouped into five groups by the receptors to which they bind: glucocorticoids, mineralocorticoids, androgens, estrogens, and progestogens..
Mineralocorticoids
class of steroid hormones characterized by their influence on salt and water balances. The primary mineralocorticoid is aldosterone
doxycorticosterone fludrocortisone
Mineralocorticoids
Mode Of Action The effects of mineralocorticoids are
mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades.
Glucocorticoids
Glucocorticoids (GCs) are a class of steroid hormones that bind to the glucocorticoid receptor (GR), which is present in almost every vertebrate animal cell.
The name glucocorticoid (glucose + cortex + steroid) derives from its role in the regulation of the metabolism of glucose, its synthesis in the adrenal cortex, and its steroidal structure
Glucocorticoids
Agents of glucocorticoids: Cortisol Prednisone Cortisone Prednisolone Dexamethasone Methylprednisolone
SAR(structure activity relationship)
Brands available
PROGESTRONE: ALGEST CYGEST CONEST CRINONE E- GEST
Brands available TESTOSTERONE:
( TESTOSTERONE ENANTHATE- GENERIC) . CORTISOL: Aclovate Acticort Aeroseb-Dex CaldeCORT Hydro-Tex Lanacort