Steroidal Hormones

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STEROIDS A steroid hormone (abbreviated as sterone) is a steroid that acts as ahormone. Steroid hormones can be grouped into five groups by the receptors to which they bind: glucocorticoids, mineralocorticoids, androgens, estrogens, and progestogens..

description

main focus on sar

Transcript of Steroidal Hormones

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STEROIDS

A steroid hormone (abbreviated as sterone) is a steroid that acts as ahormone. Steroid hormones can be grouped into five groups by the receptors to which they bind: glucocorticoids, mineralocorticoids, androgens, estrogens, and progestogens..

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Mineralocorticoids

class of steroid hormones characterized by their influence on salt and water balances. The primary mineralocorticoid is aldosterone

doxycorticosterone fludrocortisone

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Mineralocorticoids

Mode Of Action The effects of mineralocorticoids are

mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades.

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Glucocorticoids

Glucocorticoids (GCs) are a class of steroid hormones that bind to the glucocorticoid receptor (GR), which is present in almost every vertebrate animal cell.

The name glucocorticoid (glucose + cortex + steroid) derives from its role in the regulation of the metabolism of glucose, its synthesis in the adrenal cortex, and its steroidal structure

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Glucocorticoids

Agents of glucocorticoids: Cortisol Prednisone Cortisone Prednisolone Dexamethasone Methylprednisolone

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SAR(structure activity relationship)

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Brands available

PROGESTRONE: ALGEST CYGEST CONEST CRINONE E- GEST

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Brands available TESTOSTERONE:

( TESTOSTERONE ENANTHATE- GENERIC) . CORTISOL: Aclovate Acticort Aeroseb-Dex CaldeCORT Hydro-Tex Lanacort

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