State of the State in outcomes: Prescription drug overdoses Karin A. Mack, PhD Senior Behavioral...
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Transcript of State of the State in outcomes: Prescription drug overdoses Karin A. Mack, PhD Senior Behavioral...
State of the State in outcomes: Prescription drug overdoses
Karin A. Mack, PhDSenior Behavioral Scientist
Prescription Drug Overdose Team
National Center for Injury Prevention and Control
Division of Unintentional Injury Prevention
2000 2002 2004 2006 2008 20100
2
4
6
8
10
12
14
16
MV Traffic
Firearm
Poisoning
Fall
SOURCE: National Vital Statistics System-Mortality (NVSS-M), CDC/NCHS.
Injury Deaths by Cause, 1999-2010 - USAge adjusted rate per 100,000
Drug Poisoning
<11.0 11.0 - 13.9 >14.0
Age-adjusted rate per 100,000 population
10.0
9.6
7.8
8.6
10.6
6.3
3.4
6.7
7.3
14.0
11.8
11.4
9.6
14.4
13.2
15.0
23.8
11.8
10.9
11.4
19.4
10.7
6.812.7
23.6
10.9
12.9
16.9
14.6
16.1
13.0
16.9
15.3
28.9
13.1
17.5
10.4
16.4
17.0
20.7
11.6
VT 9.7NJ 9.8CT 10.1MA 11.0MD 11.0NH 11.8DC 12.9RI 15.5DE 16.6
12.5
Death Rates for Drug Overdose by State, 2010
Data: WONDER multiple causes mortality files, age-adjusted death rates for 2010. Deaths whose underlying cause was coded to unintentional (X40-44), intentional (X60-64, X85), or undetermined intent (Y10-14) drug poisoning.
Number of deaths by selected drugs involved,
US, 1999-2010
CDC/NCHS National Vital Statistics System, CDC Wonder.
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 20100
2,000
4,000
6,000
8,000
10,000
12,000
14,000
16,000
18,000
Opioids HeroinCocaine Benzodiazepines
Year
Num
ber
of
Death
s
Specific Drug Involvement in Pharmaceutical Overdose Deaths, United States, 2010
Jones et al Pharmaceutical overdose deaths, United States, 2010. JAMA 2013 and CDC/NCHS NVSS MCOD 2010.
Rx Opioids
Benzo
diazep
ines
Cocaine
Antidepressa
nts
Heroin
Other
unspec
ified narc
otics
Illicit
stimulan
ts
Antiepileptic a
nd antipark
insonism
drugs
Syste
mic and hem
atologic
al dru
gs
Antipsych
otic and neu
rolep
tic dru
gs
Acetaminophen
Respira
tory
drugs
Cardiova
scular d
rugs
Barbitu
rates
Autonomic n
ervous s
ystem
drugs
NSAID
s
Anesth
etics
and therap
eutic g
ases
Cannibas
Hormones
, insu
lins,
gluco
corti
coids
Anti-infec
tives
Diuretics an
d other
drugs
Topica
l dru
gs
Other
psych
otropic d
rugs
Muscl
e rela
xants
Other
analgesic
s
Gastro
intestinal
drugs
LSD and oth
er psy
chodys
leptics0
2,000
4,000
6,000
8,000
10,000
12,000
14,000
16,000
18,000
Drug or Drug Class
Num
ber
of D
eath
s
Deaths are the tip of the iceberg.For every opioid overdose death in 2010,
there were
SAMHSA NSDUH, DAWN, TEDS data setsCoalition Against Insurance Fraud. Prescription for Peril. http://www.insurancefraud.org/downloads/drugDiversion.pdf 2007.
Substance abuse treatment admissions 15
Emergency department visits 26
People who meet abuse or dependence criteria 115
Past year nonmedical users 733
Percent change 2000-2010Treatment admissions for Opioids*
>500
300-500<300
TEDS – Treatment episode data set ICPRS/SAMDHA*This category includes admissions for non-prescription use of methadone, codeine, morphine, oxycodone, hydromorphone, meperidine, opium, and other drugs with morphine-like effects.
National Estimates of Misuse/Abuse Drug-related Emergency Department Visits, US 2004
- 2011
Drug Abuse Warning Network http://www.samhsa.gov/data/dawn.aspx#DAWN National Tables
2004 2005 2006 2007 2008 2009 2010 20110
100,000
200,000
300,000
400,000
500,000
600,000
CocaineHeroinAntidepressantsOpiates/opioids
Rates of opioid overdose deaths, sales and treatment admissions, US, 1999-2010
1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 20100
1
2
3
4
5
6
7
8
Opioid Sales KG/10,000 Opioid Deaths/100,000Opioid Treatment Admissions/10,000
Year
Rate
Paulozzi, et al. 2011. Vital Signs: Overdoses of Prescription Opioid Pain Relievers --- United States, 1999--2008
Preliminary data
Preliminary data
<1700 1700-2400 >2400
Number of oxycodone scripts per 10,000 persons, US, 2011
Preliminary Data: IMS. Retail.
Preliminary data
Preliminary data
Oxycodone web searches
1. Tampa2. Seattle3. Orlando4. Portland5. Boston6. Phoenix7. Philadelphia8. Miami9. New York10. Atlanta
Thank You
The findings and conclusions in this report are those of the author and do not necessarily represent the views of the Centers for Disease Control and Prevention.