15:45 – 16:30

9:30 – 9:55

9:55 – 11:309:55 – 10:00 Opening - The organizers10:00 – 10:15 PHR proteins form atypical SCF ubiquitin ligase complexes to ubiquitinate and degrade substrates Muriel Desbois, Scripps Research Institute, Florida10:15 – 10:30 Regulation of Katanin, an AAA+ Microtubule-Severing Enzyme essential for early embryogenesis in C. elegans Nicolas Joly, IJM, Paris10:30 – 10:45 A V0-ATPase-dependent apical tra�cking pathway maintains the polarity of the intestinal absorptive membrane Aurélien Bidaud-Meynard, IGDR, Rennes10:45 – 11:00 Functional characterization of a nonaspanin at the inhibitory neuromuscular junction of Caenorhabditis elegans Marine Gueydan, INMG, Lyon11:00 – 11:15 CNRS UMS3421 : a CRISPR platform for C. elegans research in France Maïté Carre-Pierrat, UMS342111:15 – 11:25 A word from our sponsors: Eppendorf, Hybrigenics, Union Biometrica

14:30 – 14:45 Inter-individual variability in neuronal stress creates phenotypic variability Chauve Laetitia, The Brabahan Institute14:45 – 15:00 A natural transdi�erentiation event involving a mitosis is empowered by integrating signalling inputs with conserved plasticity factors. Gally Christelle, IGBMC, Strasbourg15:00 – 15:15 The C. elegans SET-2/SET1 histone methyltransferase maintains germline cell fate by X-linked gene silencing and repression of TGF beta signaling components Robert Valérie, LBMC, Lyon15:15 – 15:30 Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65 Methot Stephen, FMI, Basel15:40 – 15:45 Males as somatic investment in the parthenogen nematode Mesorhabditis belari Delattre Marie, LBMC, Lyon

16:30 – 16:45 C. elegans wild populations harbor natural genetic variation in non-genetic inheritance phenomena Frezal Lise, IBENS, Paris16:45 – 17:00 Natural molecular variant enhancing C. elegans dauer induction in response to diverse environmental cues Billard Benedicte, IBV, Nice17:00 – 17:15 Why are genetically identical individuals growing in the same environment phenotypically di�erent? Francesconi Mirko, LBMC, Lyon17:15 – 17:30 Lactobacillus rhamnosus Lcr35® as an e�ective treatment for preventing Candida albicans infection in the preclinical model Caenorhabditis elegans Poupet Cyril, UMRF, Clermont17:30 – 17:45 Exploring fungal virulence using C. elegans Zhang Xing, CIML, Marseille

12:30 – 13:30

18:00 – 19:30

VerMidi XXIISorbonne University

11:30– 12:30

16:30 – 18:00

14:30 – 16:00

Arrival - Welcome co�ee and registrationEsclangon building (Amphi DURAND)

Session 1 – Chair François ROBIN

Guest speaker: Sander van den HeuvelCoordinating cell proliferation and di�erentiation during development

Lunch and Posters (Caves Esclangon)Session 2 – Chair Jorge MERLET

Co�ee break (Caves Esclangon)Session 3 – Chair Flora LLENSE

Cocktail (Caves Esclangon)