SHINE ON Phase 3 FAQs · PDF file · 2017-12-28SHINE ON Phase 3 FAQs 1. IS MY DOG...
4
SHINE ON Phase 3 FAQs 1. IS MY DOG ELIGIBLE FOR TESTING? To be eligible for Phase 3 testing, your dog MUST: A. Be a purebred Golden Retriever, Portuguese Water Dog, or Boxer i. You must provide your dog’s AKC number, OR ii. If your dog is unregistered you must provide a pedigree B. Be at least 6 years old at time of enrollment C. Be in general good health D. Live in the 48 contiguous states of the U.S. 2. I KNOW MY DOG IS PUREBRED, BUT I DON’T HAVE AN AKC NUMBER OR PEDIGREE. IS MY DOG ELIGIBLE? Unfortunately, no. Samples will not be accepted for submission without either an AKC number or pedigree. 3. IS MY DOG ELIGIBLE IF HE/SHE HAS A CHRONIC OR GENETIC DISEASE? Dogs with certain chronic or genetic conditions, such as elbow or hip dysplasia, uveitis, or well controlled allergies, will be eligible. If you have questions about your dog’s health status eligibility, please contact Mitzi Lewellen, study coordinator, at [email protected] 4. DOES IT MATTER IF MY DOG IS INTACT, SPAYED, OR NEUTERED? No! Either gender, intact or altered, is eligible.
Transcript of SHINE ON Phase 3 FAQs · PDF file · 2017-12-28SHINE ON Phase 3 FAQs 1. IS MY DOG...
SHINEONPhase3FAQs
1. ISMYDOGELIGIBLEFORTESTING?TobeeligibleforPhase3testing,yourdogMUST:
A. BeapurebredGoldenRetriever,PortugueseWaterDog,orBoxer
i. Youmustprovideyourdog’sAKCnumber,ORii. Ifyourdogisunregisteredyoumustprovideapedigree
B. Beatleast6yearsoldattimeofenrollment
C. Beingeneralgoodhealth
D. Liveinthe48contiguousstatesoftheU.S.
2. IKNOWMYDOGISPUREBRED,BUTIDON’THAVEANAKC NUMBERORPEDIGREE.ISMYDOGELIGIBLE?Unfortunately,no.SampleswillnotbeacceptedforsubmissionwithouteitheranAKC numberorpedigree.
3. ISMYDOGELIGIBLEIFHE/SHEHASACHRONICORGENETIC DISEASE?Dogswithcertainchronicorgeneticconditions,suchaselboworhipdysplasia,uveitis, orwellcontrolledallergies,willbeeligible.Ifyouhavequestionsaboutyourdog’s healthstatuseligibility,pleasecontactMitziLewellen,studycoordinator,at [email protected]
4. DOESITMATTERIFMYDOGISINTACT,SPAYED,ORNEUTERED?No!Eithergender,intactoraltered,iseligible.
5. I’MAVET(ORBREEDER,ORBOTH) --CANISUBMITMYOWN DOG’SBLOOD?No,bloodmustbedrawnandsubmittedbyalicensedveterinarianwhoisnotanowner orco-ownerofthedog.Allcommunicationswillbethroughthesubmittingveterinarian, whowillsharetheresultswiththeowner.
6. MYDOGISSICKANDI’MWORRIEDTHATHE/SHEMAYHAVE CANCER.CANISUBMITBLOODTOTHISSTUDYANDFINDOUT?Thisstudyrequiresparticipantstobeingoodhealth.Ifyourdogissick,andespeciallyif yoususpectyourdoghascancer,westronglyadvisehavinghim/herexaminedbyyour dog’sveterinarian.
7. WHATHAPPENSAFTERTHETEST?Withinabout10days,thesubmittingveterinarianwillbenotifiedofoneofthe following:
A. Youwillbeaskedtosubmitanotherbloodsampleataspecifictime.Thetimingfor re-testingisdeterminedbystudyprotocol(randomized)andwillhavenospecial meaning.Mostdogswillberetestedbetween2-weeksand3-monthsapart.Some dogswillberetestedathirdtime
OR
B. Someownerswillnotbeaskedtosubmitasecondsamplefromtheirdog.Ifschedulingpermitsandiftheownerwishestohavetheirdogretested,theywillbe eligible90daysaftertheinitialtest.Itispossiblethatasecondtestmaynotbe availableforalldogs.
8. THEREPORTMYVETRECEIVEDSAYSTHATMYDOGNEEDSTOCOMEBACKINFORRE-TESTING.DOESTHISMEANMYDOG TESTEDPOSITIVEANDHASCANCER?No,thetimingforre-testingisdeterminedbythestudyprotocol(randomized)andwill havenospecialmeaning.
9. WILLMYVETERINARIANRECEIVEAREPORTTHATIDENTIFIES MYDOGAS“POSITIVE”OR“NEGATIVE?”Attheendoftesting,afinalreportwillbeprovidedtoyourdog’sveterinarianstating whethercellswerepresentinthebloodthatcouldindicateriskfordevelopmentof hemangiosarcoma.
10. WHATHAPPENSIFMYDOGTESTSNEGATIVE?Thetestlooksforspecificcellsintheblood.Dogswithincreasednumbersofthesecells mayhaveanincreasedriskofhemangiosarcoma.Bloodsamplesthatdonotcontain thesecellswillbeconsidered“negative.”Iftheschedulepermits,thesedogswillbe eligibleforre-testing90-daysaftertheirsecondtest.
11. WHATHAPPENSIFMYDOGTESTSPOSITIVE?Fordogsthathaveapositivetestresult,wewillincluderecommendationsforfollow-up inthereporttotheveterinarian.Theserecommendationswillincludethorough physicalexamination,routinelaboratorytests,andpossiblydiagnosticimagingto identifyifatumorispresent.Itisespeciallyimportanttonotethattwopositivetest resultsdonotnecessarilymeanorconfirmthatyourdoghascancer.
A. If,afteradditionaltesting,thereisnoevidenceofadetectabletumor,yourdogmay beeligibleforexperimentalpreventativetreatmentwitheBAT,offeredonlyatthe UniversityofMinnesotaVeterinaryMedicalCenter.TreatmentwitheBat consistsofthreedosesovera5-dayperiod.Schedulingfortreatmentandre-testing willbedoneforeachcaseindividually,withthegoaltomaketheexperience, includingtraveltotheTwinCities,aseasyaspossible.
OR
B. Ifatumorisfound,thedogwillnotbeeligiblefortheexperimentaltreatment,butyearlydetectionmightimprovethepotentialforsuccessfultreatment.Itisyour responsibilitytodiscusstreatmentoptionswithyourdog’sveterinarian.
12. MYDOGTESTEDPOSITIVE,BUTWECANNOTPARTICIPATEINEBATPREVENTION.SHOULDISTARTCANCERTREATMENTSOROTHERPREVENTION?No.Apositivetestdoesnotnecessarilymeanorconfirmthatyourdoghascancer. Surgery,chemotherapy,radiation,immunotherapy,herbalorcomplementarytherapies, oranyothercancertreatmentsarenotindicatedbasedontheresultsofthistest.
13. MYDOGTESTEDNEGATIVEBUTHASASTRONGFAMILY HISTORYOFHEMANGIOSARCOMA.CANIBRINGMYDOGINFOR THEEXPERIMENTALPREVENATIVETREATMENT, JUSTTOBE SAFE?No.Onlydogsthathaveapositivetestresult,asdescribedabove,willhavetheoptionof receivingtheexperimentaltreatment.
14. IHAVETWOELIGIBLEDOGS;CANIENROLLBOTHOFTHEM?Yes,youmayenrollmorethanoneofyourdogs,butwewillonlybeabletoschedulea certainnumberoftestseachweek.Whenyouarecontactedtoschedulesample submission,itmaybenecessarytoarrangesendingsamplesfromeachofyourdogson differentdays(ordifferentweeks),dependingonslotsavailable.
15. IFMYDOGISELIGIBLE,WHATISTHECOSTOFTHE EXPERIMENTALPREVENTATIVETREATMENT?Ifyourdogiseligible,theexperimentalpreventativetreatmentwillbeprovidedatthe UniversityofMinnesotaVeterinaryMedicalCenteratnocosttoyou.
16. WHATARETHESIDEEFFECTSOFTHEEXPERIMENTAL PREVENTATIVETREATMENT?Theexperimentalpreventativetreatmenthasbeengivensafelyto50dogs.Possibleside effectsincludeadrop-inbloodpressureandpossiblyanincreaseinlaboratoryvalues associatedwithliverfunction.Inourexperiencesofar,changesinbloodpressurehave beenmanageablewithinjectablesalinesolution,andthechangesinlivervalueshave correctedontheirownafterafewdays.
17. WILLTHESTUDYPAYFORCOSTSASSOCIATEDWITHTRAVELTO THETWINCITIESTORECEIVETHERAPY?Unfortunately,studyfundsarenotavailabletopayfortravelcosts.
ApplyNow>>
Orlearnmoreat:z.umn.edu/ShineOn
