SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation...
Transcript of SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation...
![Page 1: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/1.jpg)
SGSMP Physics Course for FMH residents
Radiation ProtectionandQuality AssuranceLecture by PD Dr. Uwe Schneider
![Page 2: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/2.jpg)
Contents
001 Radiation Protection Basics
002 Radiation Protection in in Medicine and Radiation-Oncology
003 Radiation Protection Legislation
004 Quality Assurance in Radiation-Oncology
RO
ENTG
ENTE
CH
NIK
STR
AHLE
NBI
OLO
GIE
GR
UN
DLA
GEN
RA
DIO
LOG
IE
STR
AH
LEN
PH
YSI
K
![Page 3: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/3.jpg)
Content001 Radiation Protection Basics
• Radiation effects
• Dose definition and dose measurement
• Radiation exposure
• Radiation damage
• Radiation risk and cancer induction
• Natural radiation
• Artificial radiation
![Page 4: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/4.jpg)
Radiation Protection Basics Effects of radiation exposureHow effective is radiation exposure?
-Radiation deposits energy in the body: in a confined volume dependent on radiation quality.
- This energy can be measured.
In the context of radiation it is true what PARACELSUS wrote:
"the dose makes the poison"
![Page 5: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/5.jpg)
Radiation Protection Basics Measurement of dose I• the need of protection againstionizing radiation,
• the application in medicine
requires quantitative methods to determine a "dose of radiation".
The purpose of a quantitative concept of a dose of radiation is:• to predict associated radiation effects (radiation detriments)
• to reproduce clinical outcomes.
![Page 6: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/6.jpg)
Radiation Protection Basics Measurement of dose II
Absorbed doseD = energy/mass [1 Joule/kg = 1 Gy]
can be measured, but:- not accounted for biological effects
- different organ sensitivity (with regard to the same absorbed dose)
- absorbed dose is a point dose
![Page 7: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/7.jpg)
Radiation Protection Basics Dose definition I
X-ray exposure:0.1 Gy x 1 = 0.1 Sv
Equivalent dose
Accounts for the effectiveness of the given radiation in inducing biological harm:
HT,R = DT x wR in Sievert (Sv)
DT = absorbed dose in GywR = weighting factor for radiation
quality
Neutron exposure:0.1 Gy x 20 = 2 Sv
![Page 8: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/8.jpg)
Radiation Protection Basics Dose definition II
20Alpha-particles, heavy ions
5Protons (energies larger than 2 MeV)
51020105
Neutrons: energy-range - below 10 keV- 10 keV - 100 keV- 100 keV - 2 MeV- 2 MeV - 20 MeV- larger then 20 MeV
1Electrons, all energies
1Photons, all energies
Weighting factor wRRadiation quality and energy
Weighting factors (StSV Anhang 1)
![Page 9: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/9.jpg)
Radiation Protection Basics Dose definition IIIFrom absorbed dose to equivalent dose
![Page 10: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/10.jpg)
Radiation Protection Basics Dose definition IV
Irradiation of thyroid:0.1 Sv x 0.05 = 0.005 Sv
Effective dose
Accounts for different organ sensitivities:
E = ΣΤHT x wT in Sievert (Sv)
HT = Equivalent dose in tissue TwT = weighting factor for tissue T
Irradiation of colon:0.1 Sv x 0.12 = 0.012 Sv
![Page 11: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/11.jpg)
Radiation Protection Basics Dose definition V
Weighting factors for different organs (StSV Anhang 1)
0.05
0.05
0.12
0.12
0.12
0.12
0.20
Weighting factor wT
Remainders
Bone surface
Skin
Thyroid
Esophagus
Liver
Organ or tissue
Breast
0.05Bladder
0.01Stomach
0.01Lung
0.05Colon
0.05Bone marrow (red)
0.05Gonads
Weighting factor wTOrgan or tissue
![Page 12: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/12.jpg)
Radiation Protection Basics Dose definition VI
From equivalent dose to effective dose
![Page 13: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/13.jpg)
Radiation Protection Basics Dose limits I
Dose limits:
- Dose limits are defined for specific person groups
- Dose limits are not applicable to medical exposures- resulting from diagnostic procedures applied in diagnosis- therapeutic procedures applied in treatment of disease.
- Dose limits are not applicable to natural exposures
- Dose limits are defined by the Radiation Protection legislation (based on ICRP-report 60, 1990)
![Page 14: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/14.jpg)
Dose limits IIRadiation Protection Basics
Public exposure
radiation
exposed to
Occupationally
Group
1
1
2
5
500
150
20
Dose limit in mSv/a
Effective Dose(without environmental and medical exposure)
Pregnant workers:incorporated dose
Pregnant workers at abdomen(Equivalent dose)
Persons between 16 and 18 years of age (effective dose)
Skin, hands, feet (Equivalent dose)
Eye lens (Equivalent dose)
Effective dose
Location and dose quality
Annual dose limits from StSV (22.06.1994)
![Page 15: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/15.jpg)
Radiation ExposureRadiation Protection Basics
A radiation exposure is each event during which dose can be absorbed
Radiation exposure can happen by:
1. Irradiation from outside: Source is outside of the body or skin is contaminated.
2. Irradiation from inside:Source is gaseous, fluid or aerosol and be inhaled or eaten.
Radiation exposures are divided into three categories:• Occupational exposure.• Medical exposure.• Public exposure.
![Page 16: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/16.jpg)
Radiation InjuryRadiation Protection Basics
Deterministic effects
• Radiation injury at large dose: H>0.5 Sv
• Complication is a function of Equivalent dose and Volume
• Certain to occur above threshold level for dose
Stochastic effects
• Malignancies and hereditary effects
• Probability of tumorinduction is function of effective dose
![Page 17: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/17.jpg)
Radiation Protection Basics Deterministic effectsLethal Dose LD50: 4 Sv
Ulceration/Perforation5065Stomach
Pneumonitis17.524.5Lung
30
10
50
55
65
23
Dosis TD5/5* [Gy]
Liver
Eye lens
Optic nerve
Skin
Bladder
Kidney
Organ
Liver failure
Cateract
Blindness
Necrosis/Ulceration
Bladder contracture
Nephritis
Endpoint
40
18
65
70
80
28
Dosis TD50/5* [Gy]
*probability of 50% and 5% complication within 5 years, respectivelyData from Emami et al, Int J rad Onc Biol Phys 1991 21 109
![Page 18: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/18.jpg)
Stochastic effectsRadiation Protection Basics
• The likelihood of stochastic effects is proportional to the effective dose received without a dose threshold.
• For radiation exposures far beyond the threshold dose
• Comparisons on the basis of effective dose:x-rays, Radiation-Oncology, natural exposures
![Page 19: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/19.jpg)
Radiation Protection Basics Radiation risk
Estimation of radiation risk:
Source: Epidemiological data from the Atomic-bomb survivors with extrapolation to low dose:
For radiation protection we assumeca. 50 cancer deaths per 1 Million persons per 1 mSv.
= 5% / Sv(linear dose-response relationship)
![Page 20: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/20.jpg)
Radiation Protection Basics Cancer induction
Dose-response relationships for radiation injury:a) Linear for cancer risk and
b) Steep gradient with threshold for acute radiation injuries
c) spontaneous, not radiation related cancer
![Page 21: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/21.jpg)
Natural radiation IRadiation Protection Basics
Biological effects of radiation:- During it’s development life on earth was exposed to ionizing radiation.
- At the beginning of life radiation exposure was much larger than nowadays.
- Radiation contributed significantly to the evolution of life.
![Page 22: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/22.jpg)
Natural radiation IIRadiation Protection Basics
Cosmic radiation exposure: - radiation from sun and outer space - is increasing with increasing height - mean exposure: 0.34 mSv/a
![Page 23: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/23.jpg)
Natural radiation IIIRadiation Protection Basics
Primordial radio-nuclides
- Primordial radio-nuclides are left over from when the world and the universe were created.
-They are typically long lived, with half-lives often on the order of hundreds of millions of years
-Most of these sources have been decreasing, due to radioactive decay since the formation of the Earth
-As a consequence some decay chains died out. Example: Plutonium-Neptunium-decay-chain
Some nuclides like 238U have several members of its decay chain
![Page 24: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/24.jpg)
Natural radiation IVRadiation Protection Basics
Terrestrial radiation: - from the earth crust - major sources are natural radium,
uranium and thorium- Swiss alpes < 1.5 mSv/a- Swiss Jura < 0.45 mSv/a
![Page 25: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/25.jpg)
Natural radiation VRadiation Protection Basics
Radioactivity in gemstones
- Exposed to radiation in order to change their color(Topas, Rubine, Saphire, etc.)
- Irradiation with electrons and x-rays is harmless
- Irradiation with neutrons, can produce other radio-nuclides (nuclear reactions) – up to 2000 Bq pro g
![Page 26: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/26.jpg)
Natural radiation VIRadiation Protection Basics
Radiation inside the human body: - Some of the essential elements that make up the human body, mainly potassium and carbon, have radioactive isotopes that add significantly to our background radiation dose.
- Incorporated with food and water mainly in muscle.- Water: nuclides from natural decay chains.- 0.45 mSv/a
![Page 27: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/27.jpg)
Natural radiation VIIRadiation Protection Basics
Radon and decay products: - Radon gas is a decay product of uranium, which is relatively common in the earth's crust.
- Radon has a short half-life (4 days) and can be inhaled and remain lodged in the lungs. It decays into other solid radioactive nuclides, causing continued exposure.
![Page 28: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/28.jpg)
Natural radiation VIIIRadiation Protection Basics
Radon and decay products: 1.6 mSv/a (0.3 ... 100 mSv/a)
![Page 29: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/29.jpg)
Natural radiation IXRadiation Protection Basics
Summary of natural radiation in Switzerland
![Page 30: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/30.jpg)
Natural radiation XIRadiation Protection Basics
Total radiation exposure in Switzerland due to natural radiation exposure
2.8 mSv/a (1.0 ... 150 mSv/a)
approximately 5% of 2’500 fatal cancers per year per 1 Million citizens originate from natural radiation (without Radon).
![Page 31: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/31.jpg)
Radiation Protection Basics Artificial radiation sources INuclear expolsions and fallout: - Frequent above-ground nuclear explosions between 1950-1965- 50% local fallout, rendering the immediate surroundings highly radioactive- 50% carried longer distances in the atmosphere; fallout due to rain. - external and internal radiation exposure- < 0.01 mSv/a
![Page 32: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/32.jpg)
Radiation Protection Basics Artificial radiation sources IISmall sources (Several materials contain radioactive nuclides):
- Illuminated displays, Glas, tiles, etc. < 0.02 mSv/a
- flying (cosmic radiation exposure)
- Tobacco: 5 mSv/a
![Page 33: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/33.jpg)
Radiation Protection Basics Artificial radiation sources III
Nuclear reactors: - Release of certain amounts of radioactive contamination
< 0.015 mSv/a
![Page 34: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/34.jpg)
Radiation Protection Basics Artificial radiation sources IVTschernobyl accident (Exposure of Swiss citizens):- Between 1986 and 2000 the mean effective dose was approximately 0.5 mSv(Maximum 5 mSv)
- Today mean effective dose: 0.01 mSv
![Page 35: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/35.jpg)
Radiation Protection Basics Artificial radiation sources V
Other sources: - Industry, Research, Hospitals < 0.03 mSv/a
Control unit of a liquid waste storage unit: monitoring of dose limits. Liquid waste from hospitals may be radioactive contaminated and must be stored before releasing into canalisation.
![Page 36: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/36.jpg)
Radiation Protection Basics Artificial radiation sources VI
Medicine:- Radiation exposure in Radiology ~1 mSv/a- radiation exposure in Nuclear Medicine and Radian-Oncology ~0.05 mSv/a
Nuclear Medicine
X-rays
![Page 37: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/37.jpg)
Radiation Protection Basics Artificial radiation sources VII
Total artificial radiation in Switzerland:
1.2 mSv/a (thereof 1 mSv/a from medicine)
![Page 38: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/38.jpg)
002 Radiation Protection in Medicine and Radiation-Oncology Content
• Radiation protection when using diagnostic sources
• X-ray imaging in Radiation-Oncology
• MV imaging in Radiation Oncology
• IMRT and Protons
• Radiation Protection of personal
![Page 39: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/39.jpg)
Radiation exposure of the patientRadiation Protection in Medicine
Radiation exposure in Radiation Oncology
Diagnostic radiation+ Simulation+ CT imaging, virtual simulation, 4D-CT + PET imaging, PET-CT imaging+ IGRT: kV-Imaging+ IGRT: ConeBeam-CT+ Imaging during radiation therapy (gated radiotherapy)
Therapeutic radiation+ IGRT: MV imaging+ IGRT: MV-ConeBeam-CT+ Radiation therapy+ IMRT
![Page 40: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/40.jpg)
Radiation exposure of the patient
Radiation Protection in Medicine
Radiation exposure during diagnostic x-rays
- Surface dose is largest dose in the patient- Organ dose is usually in the order of mSv
If you compare with natural radiation keep in mind:- Dose rate for diagnostic application can be 1’000’000 larger than with natural exposure.
- Effectiveness of radiation is increasing with increasing dose rate!
![Page 41: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/41.jpg)
Radiation Protection in Medicine Example: Effective dose
Radiation exposure of the spineCalculation of effective
dose:
E =
E = 0.7 mSv
0.5 mSv x 0.12 +0.9 mSv x 0.12 +2.0 mSv x 0.20 +0.1 mSv x 0.12 +1.0 mSv x 0.12
Stomach0.5 mSv
Lung0.1 mSv
Colon0.9 mSv
Bone marrow1 mSvOvaries
2 mSv
![Page 42: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/42.jpg)
Effective DoseRadiation Protection in Medicine
Fluoroscopy, intervenitonalx-rays> 200 mSv
Scull0.5 mSv
ThoraxTeeth
0.1 mSv
Mammography0.2 mSv
1 mSv
2 mSv
5 mSv
10 mSv
20 mSv
25 mSv
EffectiveDose
General public
Occupational exposed
Annual limit
CT-ScullPelvis
Thoracic spineAbdomen
CT-ThoraxCT-Abdomen
Bowel
Type of X-ray examination
Natural Radiation
![Page 43: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/43.jpg)
Radiation Protection in Medicine Dose ranges: x-rays
Dose intensive examinations > 0.5 mSv
- CT examinations- Serial exposures- Fluoroscopy
Dose
0.5 mSv
Low dose range < 0.5 mSv
- Single exposures of the Thorax- Single exposures of extremities- Single exposures of scull
![Page 44: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/44.jpg)
Frequency of the number of x-ray examinations
Radiation Protection in Medicine
Low dose range61%
Teeth16%
large dose9%
CT2%
Pelvis, Abdomen
12%
Total large dose 23%
If you look at frequency the low dose-range examinations contribute most
![Page 45: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/45.jpg)
Proportion of collective dose
Radiation Protection in Medicine
CT29%
large dose51%
Low dose range7%
Pelvis, Abdomen
12%Teeth1%
Gesamter Hochdosisbereich92%
If you look at total dose the dose-intensive examinations contribute most
![Page 46: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/46.jpg)
SimulationRadiation Protection in Medicine
Simulation is fluoroscopy
Radiation-induced Skin Injuries from Fluoroscopy
Dose intensive examination with doses up to 100 mSv or more
In case of an accident much more:
![Page 47: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/47.jpg)
4D-CT imaging IRadiation Protection in Medicine
- Motion is registered during CT acquisition
- Patient is scanned multiple times at each couch position
![Page 48: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/48.jpg)
4D-CT imaging IIRadiation Protection in Medicine
CT scans are sorted regarding the breathing cycle
3D imaging 4D imaging
Effective dose 3D
for head scan: 10 mSv
for abdomen scan: 20 mSv
Effective dose 4D (maximum)
100 mSv
200 mSv
![Page 49: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/49.jpg)
IGRT kV/MV imagingRadiation Protection in Medicine
kV imaging
Dose for 1 exposure ~ 0.1 … 1 mSv
Treatment with 30 fractions and two Setup-fields:
Dose ~ 6 … 60 mSv
MV imaging
Dose for 1 exposure ~0.5 … 5 mSv
Treatment with 30 fractions and two Setup-fields:
Dose ~ 30 … 300 mSv
![Page 50: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/50.jpg)
IGRT cone Beam CTRadiation Protection in Medicine
MV Cone beam CT
Dose for 1 exposure ~ 20 … 50 mSv
Treatment with 30 fractions and two Setup-fields:
Dose ~ 600 … 1500 mSv
kV Cone Beam CT
Dose for 1 CT~ 10 … 20 mSv
Treatment with 30 fractions and two Setup-fields:
Dose ~ 300 … 600 mSv
Attention:Local dose can be large!Example: H&N irradiation 3-5 Gy extra Parotid dose
![Page 51: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/51.jpg)
Impact of IMRT IRadiation Protection in Medicine
Conformal 3D irradiation
Small volume with high dose Large volume with low dose
Beam-On-Time static < Beam-on-time IMRT
IMRT
72 Gy
4 Gy
![Page 52: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/52.jpg)
Impact of IMRT IIRadiation Protection in Medicine
Comparison of different treatment techniques for prostate cancer with regard to cancer risk
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
3D-15MV IMRT-6MV IMRT-15MV Protonen(passiv)
Protonen(aktiv)
Can
cer r
isk
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
3D-15MV IMRT-6MV IMRT-15MV Protonen(passiv)
Protonen(aktiv)
Can
cer r
isk + 18% + 23%
- 46%
+ 56%
+ 2%
+ 28%
- 52%
+ 2%
Moderate increase of cancer risk when using IMRT
![Page 53: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/53.jpg)
Impact for the patientOberservations with Hodgkin-patientsCumulative cancer risk for a patient irradiated at 30 years of age is at the age of 60:Males: 18% (Comparison to general population: 7%)Females: 27% (Comparison to general population: 9%)
Radiation Protection in Medicine
![Page 54: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/54.jpg)
Content003 Radiation protection legislation
• Governmental regulation
• Registration and license
• Responsibilities in a Radiation-Oncology clinic
• Radiation protection for the personal
![Page 55: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/55.jpg)
Radiation protection legislation LegislationSwiss radiation protection legislation is based upon international recommendations of the ICRPOrganisation in Switzerland:
Regulatory authority for industrySUVASchweizerische Unfall-Versicherungsanstalt
Regulatory authority for nuclear installationsHSKHauptabteilung für dieSicherheit von Kernanlagen
Regulatory authority for medicine, teaching and researchBAGBundesamt für Gesundheit
Implementation rulesDepartments
Radiation protection regulation (StSV) from 1994Bundesrat
Radiation protection legislation (StSG) from 1991Parlament
![Page 56: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/56.jpg)
Principles
Justification- necessity and justification- benefit- benefit >> radiation risk
Optimization- ALARA
Dose limits- for general public and occupational exposed persons
- no dose limits for patients
A RAAs Low As Reasonably Achievable
Radiation protection legislation
In therapeutic medical exposure, optimization is achieve by keeping exposure of normal tissue ALARA consistent with delivering the required dose to the planning target volume (PTV).
![Page 57: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/57.jpg)
Radiation protection legislation How to get a licenseSetup and operation of a medical linear accelerator or a x-ray diagnostic device needs a license
Supports the lincenseeContractor
Applies at BAG for a license- Radiation protection building plans- Radiation protection calculations
Licensee(legal person)
Conditions fulfilled
BAG charters the license
BAG inspection after installation
Inspection ok
License with individual conditions (usually for 10 years valid)
![Page 58: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/58.jpg)
Radiation protection legislation Operation of a Linac
The operation of a linear accelerator requires:
- Existence of a medical expertise (“ärztliche Sachkunde”)- Assignment of a radiation protection officer (“Strahlenschutzsachverständige”)
- Liability insurance- The equipment must be up to date- License of the BAG- Implementation of a QA program- Comply with radiation protection legislation
![Page 59: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/59.jpg)
Responsibilities Radiation protection legislation
- all patients which accumulate more than 1 mSv of dose- responsible for using their personal dosimeter
Occupational exposed persons
- Qualification for Radiation-Oncology („Facharzt“)- medical responsibility for diagnostic and therapeutic application of ionising radiation to patients
Medical expert(Radiation Oncologist)
- qualification as a Medical Physicist- implement radiation protection rules in the clinic- responsibility for radiation protection
Radiation protection officer(Medical Physicist)
- responsibility that the hospital complies to radiation protection legislation
- assign radiation protection officer- must guarantee safety in the hospital
Licensee(legal persons, usually hospital administration)
![Page 60: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/60.jpg)
Personal dosimetry I Radiation protection legislation
Determination of radiation dose (Dosimetry) (Art.42ff):
The licensee must determine radiation exposure of all occupational exposed persons in his hospital, each person individually and on a monthly basis, by an accrediteddosimetry lab.- He has to inform his employees about the measurements.- he hast to pay the costs for the dosimetry.
![Page 61: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/61.jpg)
Personal dosimetry II Radiation protection legislation
Personal dose report (Art.57):
The licensee has to register the accumulated dose in the personal radiation report on a yearly basis.
When employment stops the occupational exposed person receives the dose report with the accumulated dose from the licensee.
![Page 62: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/62.jpg)
004 Quality Assurance in Radiation-Oncology Content
• Definition and organisation of quality assurance
• Quality assurance for equipment
• Quality assurance for treatment delivery
![Page 63: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/63.jpg)
QA in radiotherapy IQuality Assurance
Quality assurance in radiotherapy"Quality Assurance in Radiotherapy" is all procedures that ensure
consistency of the medical prescription, and safe fulfillment of that radiotherapy related prescription.
Examples of prescriptions:
• the dose to the tumor (to the target volume)
• minimal dose to normal tissue
• adequate patient monitoring aimed at determining the optimumend result of the treatment
• minimal exposure of personnel
![Page 64: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/64.jpg)
QA in radiotherapy IIQuality Assurance
Quality standards is the set of accepted criteria against which the quality of the activity in question can be assessed.
In other words: Without quality standards, quality cannot be assessed.
Quality standards in radiotherapyRecommendations of international organisations (WHO, ESTRO,…)
Regulation by the Swiss authorities: “Linear accelerator ordinance” (Beschleunigerverordnung, BeV, 25.01.2005):
“The licensee has to establish a ongoing QA-program based on international accepted standards, which incorporates both, the medical aspects of radiotherapy and the equipment-specific and medical physics issues.”
![Page 65: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/65.jpg)
QA in radiotherapy IIIQuality Assurance
Why does a radiotherapy center need a quality system?
1. You must establish a QA program because it is law!
2. It helps to provide “the best treatment”.
3. It provides measures to approach the following objectives:
Reduction of uncertainties and errors (in dosimetry, treatment planning, equipment performance, treatment delivery, etc.)
Reduction of the likelihood of accidents and errors
Providing reliable inter-comparison of results among different radiotherapy centers
Full exploitation of improved technology
![Page 66: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/66.jpg)
QA for equipment IQuality Assurance
General structure of a quality assurance program for equipment (under the responsibility of the Medical Physicist)
![Page 67: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/67.jpg)
QA for equipment IIQuality Assurance
Acceptance
Acceptance of equipment is the process in which the supplier demonstrates the baseline performance of the equipment to the satisfaction of the customer.
Commissioning
Commissioning is the process of preparing the equipment for clinical service.
Quality control
An ongoing program of regular performance checks to verify that treatment equipment remain consistent within accepted tolerances throughout its clinical life.
![Page 68: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/68.jpg)
QA for treatment delivery IQuality Assurance
Patient charts (Radiation-Oncologist and Medical physicist)
The radiation chart is accompanying the patient during the entire process of radiotherapy.
Basic components of a patient treatment chart:• patient name and ID,• photograph,• initial physical evaluation of the patient,• treatment planning data,• treatment execution data,• clinical assessment during treatment,• treatment summary and follow up.
Any mistakes made at the data entry of the patient chart are likely to be carried through the whole treatment.
QA of the patient chart is therefore essential!
![Page 69: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/69.jpg)
QA for treatment delivery IIQuality Assurance
Portal imaging (Radiation-Oncologist and Therapist)
Portal imaging is frequently applied in order to check geometricaccuracy of the patient set-up with respect to the position of the radiation beam.
Process control requires that local protocols must be established to specify:
• who has the responsibility for verification of portal images (generally a clinician), and
• what criteria are used as the basis to judge the acceptability of information conveyed by portal images.
![Page 70: SGSMP Physics Course for FMH residents · SGSMP Physics Course for FMH residents Radiation Protection and Quality Assurance Lecture by PD Dr. Uwe Schneider](https://reader033.fdocuments.us/reader033/viewer/2022051809/60156df25951ea6ec2719e45/html5/thumbnails/70.jpg)
QA for treatment delivery IIIQuality Assurance
Record-and-verify systems (Medical physicist and Therapist)
At the time of treatment, patient related parameters are identified at the treatment machine and, if there is no difference, the treatment can start.
If discrepancies are present this is indicated and the parameters concerned are highlighted. Treatment cannot start.
In-vivo dose measurements (Medical physicist)
There are many steps in the chain of processes which determine the dose delivery to a patient. Each of these steps may introduce an uncertainty.
It is therefore necessary for specific patient groups or for unusual treatment conditions to use in-vivo dosimetry as an ultimate check of the actual treatment dose.