Seminar on Jumping Genes by LK

Siri Seminar Genomik Tumbuhan Pusat Pengajian Sains Sekitaran dan Sumber Alam, Fakulti Sains & Teknologi, Universiti Kebangsaan Malaysia Date: 15 Nov. 2011 Venue: Seminar Room G143, FST 1000-1030 Refreshments 1030-1200 Jumping Genes Jumble the Genome -Dr. Lakshminarasimhan Krishnaswamy Jumping Genes Jumble the Genome Dr. Lakshminarasimhan Krishnaswamy, School of Science, Monash University Sunway campus, Malaysia Email: [email protected] Abstract Transposable elements (also known as ‘jumping genes’) are mobile genetic elements that can move from one locus in the genome to another. It was Barbara McClintock who discovered transposable elements when she was studying a particular variegation pattern of pigmentation in maize kernels. Initially the phenomenon of transposition was considered to be an anomalous feature unique to maize. In the years that followed we have learnt that transposons are found in all species, and in fact, transposable elements contribute to a large fraction of the genome in most eukaryotes. In addition to moving from one locus to another in the genome, transposable elements can also cause a wide variety of genome rearrangements. In this seminar we will discuss the different kinds of rearrangements, the mechanism of rearrangements, the implications of such rearrangements, and the utility of such rearrangements in chromosome engineering. Background biography of speaker: Lakshminarasimhan Krishnaswamy obtained his BSc in Botany from The American College, Madurai, India. He joined the National Centre for Biological Sciences (NCBS), Bangalore, India, for his MSc and studied differential expression of genes in the brain of epileptic rats. However he realized he wasn’t comfortable doing research using animals and decided to move back to plants. He pursued his Ph.D. under the guidance of Dr. Thomas Peterson at Iowa State University, Ames, Iowa, USA, where he studied transposon mediated genome rearrangements in Arabidopsis. Then he moved to University of Missouri, Columbia, Missouri, USA, for a postdoctoral stint in Dr. James Birchler’s lab. Here he was involved in a project generating minichromosomes in maize. He has recently joined the School of Science, Monash University Sunway campus, where he enjoys teaching and is aspiring to establish a research lab to develop transposon based tools for genome engineering. Convenor: Prof. Dr. Wickneswari Ratnam, PPSSSA, FST

Upload
ahmad-ismail
Category

Documents
view
43
download
3

Embed Size (px):

Transcript of Seminar on Jumping Genes by LK

Siri Seminar Genomik Tumbuhan

Pusat Pengajian Sains Sekitaran dan Sumber Alam, Fakulti Sains & Teknologi, Universiti

Kebangsaan Malaysia

Date: 15 Nov. 2011

Venue: Seminar Room G143, FST

1000-1030 Refreshments 1030-1200 Jumping Genes Jumble the Genome

-Dr. Lakshminarasimhan Krishnaswamy

Jumping Genes Jumble the Genome

Dr. Lakshminarasimhan Krishnaswamy,

School of Science,

Monash University Sunway campus, Malaysia Email: [email protected]

Abstract

Transposable elements (also known as ‘jumping genes’) are mobile genetic elements that can move from one locus in the genome to another. It was Barbara McClintock who discovered transposable elements when she was studying a particular variegation pattern of pigmentation in maize kernels. Initially the phenomenon of transposition was considered to be an anomalous feature unique to maize. In the years that followed we have learnt that transposons are found in all species, and in fact, transposable elements contribute to a large fraction of the genome in most eukaryotes.

In addition to moving from one locus to another in the genome, transposable elements can also cause a wide variety of genome rearrangements. In this seminar we will discuss the different kinds of rearrangements, the mechanism of rearrangements, the implications of such rearrangements, and the utility of such rearrangements in chromosome engineering.

Background biography of speaker:

Lakshminarasimhan Krishnaswamy obtained his BSc in Botany from The American College, Madurai, India. He joined the National Centre for Biological Sciences (NCBS), Bangalore, India, for his MSc and studied differential expression of genes in the brain of epileptic rats. However he realized he wasn’t comfortable doing research using animals and decided to move back to plants. He pursued his Ph.D. under the guidance of Dr. Thomas Peterson at Iowa State University, Ames, Iowa, USA, where he studied transposon mediated genome rearrangements in Arabidopsis. Then he moved to University of Missouri, Columbia, Missouri, USA, for a postdoctoral stint in Dr. James Birchler’s lab. Here he was involved in a project generating minichromosomes in maize. He has recently joined the School of Science, Monash University Sunway campus, where he enjoys teaching and is aspiring to establish a research lab to develop transposon based tools for genome engineering.

Convenor: Prof. Dr. Wickneswari Ratnam, PPSSSA, FST