semi-invasive biopotential & activity in rodents

on each subject the following 8 signals are available:

2 eeg, each sampled at 1kHz

2 emg/ecg, each sampled at 500Hz

3 axis acceleration, sampled at 80Hz on each axis

1 global acceleration module available at 80Hz, computed from 3 axes

rodentPACK is a semi-invasive telemetry device to monitor biopotentials and activity on rats

rodentPACK consists of 3 main parts

electrodes implanted in the subject and linked to a connector permanently glued onto the skull

transmitter housing amplifiers, transmission electronics and batteries, to be coupled to the head connector prior to experiment

receiver to read transmistted data and to provide calibrated analog outputs

radio transmission range, 5m or more

transmission duration with same batteries: 70 hours(cost of batteries: 3€ ($4US) / pair)

group housing: multiple animals in same cage

20 to 40 animals in same room with no required shielding

analog outputs: connects at no extra cost to any existing software

features

noise free, high quality eeg signaleeg electrodes are rigidly welded on the head connector which is itself solidly linked to the transmitter, therefore animal movements trigger no flexible wire movement and cause no artefact

3-axis acceleration allowing activity and posture assessment

very low recurring costno transmitter refurbishment is ever necessary batteries cost 3€ per recording

advantages

low investment costto record simultaneously from 4 rats, your complete hardware investment is less than 13k€ ($18kUS)

even lower investment costby scheduling your recordings, you may further decrease cost

for example, conducting a study on 16 subjects split in 4 groups of 4, only requires a total hardware investment of 14k€ ($20kUS)

open system if you already own a preferred acquisition/analysis software, you may use it at no extra cost : rodentPACK is provided with analog outputs and immediately connects to any recording platform

more advantages

5s of data from a rat cortex, hippocampus, emg, total acceleration

data traces from rodentPACK

50 s of data from a rat cortex, hippocampus, emg, total acceleration

data traces from rodentPACK

does the device alter subject behaviour?

after an acclimation of under 24 hours, the rats ignore the device. They do not « touch » it nor do they try to rub it on the cage sides

how long can the implanted electrodes and glued connector stay in place ?

rats equipped with this types of electrodes and connectors have been routinely used for many years in tethered systems

rats used for our tests were implanted 12 months ago and are still in good health. No special precautions were taken during this period to keep the skin-to-glue junction clean or sterile

frequently asked questions

power in up to 6 adjustable frequency ranges

absolute and relative power values

versatile scheduling of analysis, epoch lengths, overlap factor, windowing

power spectrum analysis with eeg module within ecgAUTO software

3-D display of average spectrums over time

power spectrum analysis with eeg module within ecgAUTO software

sleep scoring moduledefine threshold values applicable to any parameter from any input

software applies logical rules to attribute 1 out of 4 sleep stages to each epoch

trend graph displays parameters as well as sleep stages

user may, on the fly, adjust thresholds and see the effect on sleep scoring

from top:cortexhippocampusmuscle

sleep scoreactive wakequiet wakeREM sleepSW sleep

sleep scoring module

sleep scoring module

from top:cortexhippocampusmuscle

data table(one line per 20s epoch)

visit our websites for complete product descriptions, case studies, a knowledge base, & frequently asked questions:

www.emka.fr

website

please contact us to see how we can help you meet your telemetry research goals!

contact us!