Semesterrapport 2007 - 2, 01.05.2007 – 31.08.2007

Forskningsenheden for Almen Praksis i Odense og Audit Projekt Odense (APO)

Organisation Personale

Cand.med. Malene Plejdrup er i perioden 1. juni – 30. november ansat som klinisk assistent (forskningsassistent). Jon Eik Zwisler har den 31. august indleveret sin ph.d.-afhandling ”Discontinuation of long-term antisecretory treatment in general practice” til Det Sundhedsvidenskabelige Fakultet med henblik på offentligt forsvar.

Lokaler og økonomi Forskningsenheden har fra Indenrigs- og Sundhedsministeriet modtaget en bevilling på kr. 1.500.000 til ”Styrkelse af infrastruktur for klinisk kræftforskning”. Morten Andersen har fra Indenrigs- og Sundhedsministeriet modtaget en bevilling på kr. 1.800.000 til projektet ”KOL og lægemiddelanvendelse”. Charlotte Harmsen og Mette Koefoed har fået tildelt Danmarks Forskerskole i Folkesundhedsvidenskabs GRASPH-stipendium.

Publikationer (publicerede) Originale

Callreus T, Andersen UA, Hallas J, Andersen M. Cardiovascular drugs and the risk of suicide: a nested case-control study. Eur J Clin Pharmacol 2007;63:591-6. Hald M, Hansen DG, Blands J, Agner T, Johansen JD. Viden om handlingsstrategier vedrørende håndeksem i almen praksis. Ugeskr Læger 2007;169:2772-6. Hallas J, Dall M, Andries A, Andersen BS, Aalykke C, Hansen JM, Andersen M, Lassen AT. Brug af antitrombotisk behandling i monoterapi eller kombination og risikoen for øvre gastrointestinal blødning: Et populations-baseret case-kontrol studie. Sekundærpublikation. [Use of antithrombotic treatment in monotherapy or combination and the risk of gastrointestinal bleeding]. Ugeskr Læger 2007;169:1577-9. Halvorsen PA, Selmer R, Kristiansen IS. Different ways to describe the benefits of risk-reducing treatments: a randomized trial. Ann Int Med 2007;146:848-56.

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Hansen DG, Dybdahl T, Jarbøl D, W Vach. Clinical interest: a study of the influence on general practitioners’ prescribing. Pharmacoepidemiology and Drug Safety 2007;16:458-63. Hansen DG, Gichangi A, Vach W, Felde LH, Larsen J. Early discontinuation: more frequent among general practitioners with high levels of prescribing. Eur J Clin Pharmacol 2007;63:861-5. Holm A, Nexøe J, Bistrup LA, Pedersen SS, Obel N, Nielsen LP, Pedersen C. Aetiology and prediction of pneumonia in lower respiratory tract infection in primary care. Br J Gen Pract 2007;57:547-54.

Holm A, Pedersen SS, Nexoe J, Obel N, Nielsen LP, Koldkjaer O, Pedersen C. Procalcitonin versus C-reactive protein for predicting pneumonia in adults with lower respiratory tract infection in primary care. Br J Gen Pract 2007;57:555-60

Kristiansen IS, Gyrd-Hansen D. Prioritering og helse – bør det innføres en makspris på leveår? Tidsskr Nor Lægeforen 2007;127:54-7. Ledderer L, Kragstrup J, Bro F. Praksispersonalets deltagelse i forebyggelse i almen praksis. Erfaringer fra et udviklingsprojekt iværksat af Fyns Amt. Odense: Forskningsenheden for Almen Praksis og Fyns Amt, juli 2007. Schramm J, Andersen M, Vach K, Kragstrup J, Kampmann JP, Søndergaard J. Promotional methods used by representatives of drug companies. A prospective survey in general practice. Scand J Prim Health Care 2007;25:93-7. Uhlig T, Loge JH, Kristiansen IS, Kvien TK. Quantification of reduced health-related quality of life in patients with rheumatoid arthritis compared to the general population. J Rheumatology 2007. E-pub ahead of print. Yoon LS, Nexøe J, Nielsen JB. Risikoformidling – et spørgsmål om tilfældigheder? Ugeskr Læger 2007;169:2325-8.

Formidlende

Bjerrum L. Angiotensin II-antagonister. Info-.Med 2007; Årgang 18 nr. 7, 5. juni. Kragstrup J. Patienter er tilfredse, selv når læger ikke indfrier forventningerne. (Kort Nyt, Medicinske Nyheder). Ugeskr Læger 2007;169:2177. Kristiansen IS. Evidence based medicine – time for asking critical questions? ISPOR Connections. The Official News & Technical Journal of the International Society of Pharmacoeconomics and Outcomes Research 2007;13:4-7. Jarbøl D. Behandling af dyspepsi – specielt i primærsektoren. Rationel Farmakoterapi Nr. 6, juni 2007.

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Støvring H. Flere sukkersyge vil skabe problemer. Interview til Berlingske Tidende, 24. maj. Støvring H. Antallet af sukkersyge vil fordoble sig på 10 år. Interview til Politiken, 24. maj. Støvring H. Forkerte beregninger. Ny Viden, Nr. 6. juni, 2007:4-6. Støvring H. Eksplosion i sukkersygepatienter. Interview til Nyhedsavisen, 30. maj.

Enhedens aktiviteter Arrangementer og gæster

En delegation fra Vologda, Rusland, bestående af hospitalsledere og -administratorer besøgte den 22.-23. maj APO og Forskningsenheden for at få information om den danske primære sundhedstjeneste.

Undervisning, kursusledelse

Bjerrum L. Underviser på forskertræningskursus på Specialeuddannelsen i Almen Medicin, Snaptun, 9.-10. maj. Kragstrup J. Underviser på forskertræningskursus på Specialeuddannelsen i Almen Medicin, Snaptun, 9.-10. maj. Underviser på forskertræningskursus på Specialeuddannelsen i Almen Medicin, Syddansk Universitet, Odense, 18.-20. juni, 30. august. Støvring H. Censor i ”Epidemiologi og statistik” på Den Sundhedsvidenskabelige Suppleringsuddannelse ved Aarhus Universitet, juni. Censor i ”Klinisk epidemiologi og biostatistik” på Den Sundhedsvidenskabelige Kandidatuddannelse ved Aarhus Universitet, juni. Zwisler JE. Underviser på Specialeuddannelsen i Almen Medicin, Syddansk Universitet. Underviser på medicinstudiets Blok 3 i Kommunikation, Syddansk Universitet.

Deltagelse i grupper og udvalg (Nyt siden sidste rapport)

Kragstrup J. Medlem af interviewpanel i forbindelse med optagelse på medicinstudiets kvote 2, Syddansk Universitet, 22. maj.

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Medlem af bedømmelsesudvalg vedrørende doktorand ved Nordiska Högskolan för Folkhälsovetenskab (NHV), Göteborg, 5. juni. Formand for bedømmelsesudvalg vedrørende ph.d.-afhandling (Helle Rexbye) ved Syddansk Universitet.

Deltagelse i kongresser og lign. Andersen M. 23rd International Conference on Pharmacoepidemiology (ICPE), Quebec City, Canada, 19.-22. august. Bjerrum L. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Felde LH. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Harmsen CG. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Hansen DG. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Research Management Course, Uddannelse af Forskningsledere, Copenhagen Business School, Sorø (3 x 3 dage), 18.-20. juni, 26.-28. september, 19.-21. november. Halvorsen P. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Kildemoes HW. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. 23rd International Conference on Pharmacoepidemiology (ICPE), Quebec City, Canada, 19.-22. august. Kragstrup J. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Møde for nordiske redaktører, Malmö, 31. august. Kristiansen IS. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. iHEA World Congress of Health Economics, København, 10. juli.

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Nexøe J. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Støvring H. Joint Statistical Meeting, Salt Lake City, Utah, USA, 1.-4. august. Zwisler JE. Nordic Meeting in Gastroenterology, 5.-8. juni, Reykjavik, Island.

Individuelle foredrag

Andersen M. Assessing the validity of prescribing quality indicators. ISPE Introduction to Drug Utilization/Health Services Research. 23rd International Conference on Pharmacoepidemiology (ICPE), Quebec City, Canada, 19.-22. august. Bjerrum L. Can the Nordic Audit Project Odense (APO) method be used to reduce inappropriate prescribing in Spain? 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Treatment of uncomplicated acute cystitis in general practice. Should my patient be prescribed Sulfamethizole or Pivmecillinam? 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. The HAPPY AUDIT Project. Symposium. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Anvendelse af CRP-måling i almen praksis, CRP workshop, Oslo, 19.-20. juni. Felde LH. Handling hypercholesterolemia in everyday life – patients’ treatment decisions. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Halvorsen P. Mitt prosjekt. Prosjekter som illustrerer ulike metoder for forskning i allmennmedisin. Grundkursus III i specialeuddannelsen i almen medicin, Tromsø, 10. maj. Halvorsen P, Nexøe J, Kristiansen IS. Explaining risk reductions to patients – what numbers should GPs use? Workshop arrangeret af Halvorsen P, Nexøe J og Kristiansen IS. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Hansen DG. Livet som ph.d.-studerende. Ups and Downs! Internatmøde, Danmarks Forskerskole i Folkesundhedsvidenskab, Middelfart, 7. maj.

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Guidelines for quality development in general practice. The Audit Project Odense (APO) method. Russisk delegation af hospitalsledere, Odense, 22. maj. Harmsen CG. Interventions for chronic diseases: Effect of patient values and effectiveness information on patients’ choice of therapy, adherence to therapy and satisfaction with therapy. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Kildemoes HW. Driving forces behind the increasing cardiovascular treatment intensity. A prescription epidemic? 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Driving forces behind the increasing cardiovascular treatment intensity. A dynamic epidemiologic model of trends in Danish cardiovascular drug utilization. 23rd International Conference on Pharmacoepidemiology (ICPE), Quebec City, Canada, 19.-22. august. Kragstrup J. Sammenhæng for kræftpatienter. Onkologisk Staff Meeting, Odense Universitetshospital, 2. maj. Promoting research in general practice. The Scandinavian Journal of Primary Health Care’s 25th Anniversary Symposium. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Kristiansen IS. Koster det mer enn det smaker? – om prioriteringer av helsetilbud, kost/nytte-analyser og samfunnets betalingsvillighet. Seksjon for medisinsk etikk, Universitetet i Oslo, 8. maj. Hva vil samfunnet betale for liv og helse? Årsmøde i Nordland Legeforening, Bodø, 10. maj. Biologiske legemidler – er de verdt prisen? Schering-Ploughs tværfaglige møde om psoriasis og Crohns sygdom i Oslo, 11. maj. Medikamentavgivende stenter – er de kostnadseffektive? Stabsmøde Rikshospitalet, Oslo, 11. maj. Hvor effektiv er forebyggning av hjerte- og karsykdom – misforståelse og forståelse. Diabetesforum, Oslo, 12. maj. Støvring H. Estimation of incidence of first time ever treatment, prevalence of paused treatment, and prevalence of active treatment from pharmacoepidemiologic claims data. Joint Statistical Meeting, Salt Lake City, Utah, USA, 1.-4. august.

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Abstracts

Bentzen N, Hansen DG, Damsgaard J, Eriksson U, Bjerrum L. Respiratory tract infections: Quality improvement based on literature search and activity registration in daily practice. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Bjerrum L, Gahrn-Hansen B, Grinsted P. Treatment of uncomplicated acute cystitis in general practice. Should my patient be prescribed Sulfamethizole or Pivmecillinam? 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Damsgaard J, Gahrn-Hansen B, Larsen BO, Schæfer K, Hansen DG, Munck A. Patients’ point-of-view regarding their treatment for respiratory tract infections (RTIs). (Poster) 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Drivsholm T, Jørgensen BS, Rytter L, Schultz-Larsen P, Jensen JB, Munck A. Teambuilding within general practice. Implementation of diabetes guidelines in 42 general practices in Denmark. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Felde LH, Larsen J, Kragstrup J, Larsen K, Elverdam B. Handling hypercholesterolemia in everyday life – patients’ treatment decisions. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Frederiksen HB, Kragstrup J, Dehlholm G. Continuity in general practice: It’s all about recognition! (Poster) 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Halvorsen P, Nexøe J, Kristiansen IS. Explaining risk reductions to patients – what numbers should GPs use? 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Hansen DG, Damsgaard J, Foged L, Holst PE, Schultz-Larsen M, Poulsen L, Munck A. Quality improvement of nurses’ and secretaries’ tasks in daily clinic: Activity survey based on the APO registration charts. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Hansen DG, Dybdahl T. Jarbøl D, Vach W. Clinical interest: A study of the influence on general practitioners’ prescribing. (Poster) 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Hansen DG, Veje JO, Bjerregaard P, Munck A. Adult attenders in primary care in Greenland: Information on reason for encounter and lifestyle risk factors sampled on an APO registration chart. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Harmsen CG, Kristiansen IS, Nexøe J, Gyrd-Hansen D, Edwards A. Interventions for chronic diseases: Effect of patient values and effectiveness information on patients’ choice of therapy, adherence to therapy and satisfaction with therapy.

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15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Kildemoes HW, Støvring H, Andersen M. Driving forces behind the increasing cardiovascular treatment intensity. A prescription epidemic? 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Kildemoes HW, Støvring H, Andersen M. Driving forces behind the increasing cardiovascular intensity. A dynamic epidemiologic model of trends in Danish cardiovascular drug utilization. (Poster). Abstract i Pharmacoepidemiol Drug Safety 2007;16:S85. 23rd International Conference on Pharmacoepidemiology (ICPE), Quebec City, Canada, 19.-22. august. Kragstrup J, Håkansson A, Bærheim A, Sigurdsson JA, Virjo I, Sandbæk A, Rörtveit G. Promoting research in general practice. The Scandinavian Journal of Primary Health Care’s 25th Anniversary Symposium. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Lindbæk M, Mölstad S, Gjelstad S, Arason VA, Bjerrum L. Use of antibiotics and bacterial resistance. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Llor C, Bjerrum L, Cots JM, Molist N, Munck A, Bayona C. Can the Nordic Audit Project Odense (APO) method be used to reduce inappropriate antibiotic prescribing in Spain? 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Munck A, Hansen DG. Overfølsomhedssygdomme i almen praksis 2005/2006 – en spørgeskemaundersøgelse. Årsmøde i Dansk Selskab for Allergologi, Kolding, 17.-18. august. Nexøe J, Aaen-Larsen B, Stauning JA. University practices of family medicine in Denmark. It is not just building a bridge… (Poster) 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Obel C, Schroll H, Andersen MK, Christensen B, Andersen M, Søndergaard J. Preschool children in risk of overweight. The development of a strategy for monitoring and early intervention in a general practice setting. 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Poulsen L, Hansen DG, Damsgaard J, Brixen K, Munck A. Prevention of osteoporotic fractures among 60+ year-olds in general practice: Activity survey based on the APO registration charts. (Poster) 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Rasmussen DM, Elverdam B. The rehabilitation process of cancer patients. (Poster) 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Støvring H, Gyrd-Hansen D, Kristiansen IS, Nexøe J, Nielsen JB. Communicating effectiveness of intervention for chronic diseases: What single risk format results in the ”best” decisions?

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15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Sørensen JB, Kragstrup J, Skovgaard T, Puggaard L. Exercise on prescription: Short and long term effects. (Poster) 15th Nordic Congress of General Practice, Reykjavik, Island, 13.-16. juni. Wisløff TF, Abel JO, Gyrd-Hansen D, Kristiansen IS. Preferences for life extensions vs risk reductions: Some theoretical and methodological contributions. iHEA World Congress of Health Economics, København, 10. juli. Zwisler JE. Discontinuing long-term antisecretory treatment – a randomized, blinded, placebo-controlled trial in primary care. Nordic Meeting in Gastroenterology, 5.-8. juni, Reykjavik, Island.

Audit Projekt Odense APO-NYT udsendes i løbet af efteråret. Jakob Kragstrup September 2007