ASCAAAnnual Report

2016-17

“Together We Can Fight this Disease”

In Kind Donations continued

Cleveland MetroparksCleveland Urban WineryWalden SpaArt by KristiApple American GroupALDIBaskets by MauryPamela BradfordDr. Maemie Chan, DMDA Christmas Story HouseCleveland CavaliersDanny’s Auto Body Service ShopDouble Tree Hilton Tudor ArmsThe Gidden House Luxury Boutique HotelGourmetGiftBaskets.comOrban’s Fruit & FlowersRenaissance HotelTiffjknits2Waterway Gas & WashSoaps By UsWhole Foods MarketGary WilliamsTower City Car Wash

Donations in MemoryCarmin Awadzi (In Memory of Rod Young II)Shirley B. Barnes (In Memory of Mr. Jarett Charles Brigham)Richard J. Beck (In Memory of Mr. Jarett Charles Brigham)Joseph H. Berman (In Memory of Dr. Harold & Mrs. Muriel

Ford)Connie Reagan-Blake (In Memory of Jarett Charles Brigham)Carolyn Brigham (In Memory of Jarett Charles Brigham)Mickey Brown (In Memory of Jarett Charles Brigham)David V. Bryant (In Memory of Cecilla Noell Evans)CC (In Memory of Laura Oliver Armstrong)Kareann Carty (In Memory of James Anthony Bronston)Geneva Chambers (In Memory of LaShawn Krystal)Diana J. Coleman (In Memory of Wesley H. Coleman)Michael Cousin (In Memory of Lauren King)Stacy L. & Peyton Evans (In Memory of Cecilla Noell Evans)Darnelle Gillisslee (In Memory of Mr. Jarett Charles Brigham)Martin K. & Maureen L. Hartwell (In Memory of Jarett Charles Brigham)Walter Higgins (In Memory of LaShawn Krystal Chambers)Constance Hines (In Memory of Jarett Charles Brigham)Alan Hoal (In Memory of Jarett Charles Brigham)Lawanda Hoes (In Memory of Tamia Simms)Linda House (In Memory of Janice Davis-Ford & Marcos

Davis)Robert James (In Memory of Mr. Jarett Charles Brigham)

Selina M. Jarrett (In Memory of Caroline Davis)Beryl Kelley (In Memory of Jarett Charles Brigham)Jim Lehner (In Memory of Jarett Charles Brigham)Elizabeth London (In Memory of Janice Davis- Ford &

Marcos Davis)Joan Leotta (In Memory of Jarett Charles Brigham)Myra M. Lewis (In Memory of Ms. Stella M. Rochon)Lester Lynch (In Memory of My sister, Lucinda Lynch) Rianna Mallard (In Memory of Jarett Charles Brigham)William Marable (In Memory of Jarett Charles Brigham)Chris Mullaney (In Memory of Jarett Charles Brigham)Mary O’Brien (In Memory of James Anthony Bronston)Oliver Armstrong Family (In Memory of Laura Oliver Armstrong) Ugonna Okpalaoka (In Memory of Lauren King)Tijuana G. Pitt (In Memory of Brain Keith Duncan &

Milford Keith Duncan Jr.) Frances Plantikow (In Memory of Jarett Charles Brigham)Sheila Rylander (In Memory of Mrs. Paulette Ford)Norris Spencer (In Memory of Jarett Charles Brigham)Daniel & Jodi Taylor (In Memory of Mr. Wesley H. Coleman)Donna Washington (In Memory of Jarett Charles Brigham)Charles Wetzelberger (In Memory of Jarett Charles Brigham)Jeff & D. Welter (In Memory of Audi Roberts)Rod Young (In Memory of Rod Young II)Jeff Welter (In Memory of Audi Roberts)

Donations in HonorKari A. Cunningham (In Honor of Gerald V. Cunningham) Diane Dickinson-Watkins (In Honor of Gerald V. Cunningham) Ms. Gabriela Satele (Arabian Stars #174) (In Honor of Worthy Matron, Dalia

Corredor)

Thank you for your continued supportBoard of Trustees

Staff & Consumers

OverviewCells in tissues need a steady supply of oxygen to work well. Normally, hemoglobin in red blood cells takes up oxygen in the lungs and carries it to all the tissues of the body. Red blood cells that contain normal hemoglobin are disc shaped (like a doughnut without a hole). This shape allows the cells to be flexible so that they can move through large and small blood vessels to deliver oxygen. Sickle hemoglobin is not like normal hemoglobin. It can form stiff rods within the red cell, changing it into a crescent, or sickle shape.Sickle-shaped cells are not flexible and can stick to vessel walls, causing a blockage that slows or stops the flow of blood. When this happens, oxygen can’t reach nearby tissues. The lack of tissue oxygen can cause attacks of sudden, severe pain, called pain crises. These pain attacks can occur without warning, and a person often needs to go to the hospital for effective treatment. Most children with SCD are pain free between painful crises, but adolescents and adults may also suffer with chronic ongoing pain. The red cell sickling and poor oxygen delivery can also cause organ damage. Over a lifetime, SCD can harm a person’s spleen, brain, eyes, lungs, liver, heart, kidneys, penis, joints, bones, or skin. Sickle cells can’t change shape easily, so they tend to burst apart or hemolyze. Normal red blood cells live about 90 to 120 days, but sickle cells last only 10 to 20 days. Sickle cell disease is a life-long illness. The severity of the disease varies widely from person to person. At the present time, hematopoietic stem cell transplantation (HSCT) is the only cure for SCD. Unfortunately, most people with SCD are either too old for a transplant or don’t have a relative who is a good enough genetic match for them to act as a donor. A well-matched donor is needed to have the best chance for a successful transplant. Source: NIH-08/20/2017

hemolyze. Normal red blood cells live about 90 to 120 days, but sickle cells last only 10 to 20 days. Sickle cell disease is a life-long illness. The severity of the disease varies widely from person to person. At the present time, hematopoietic stem cell transplantation (HSCT) is the only cure for SCD. Unfortunately, most people with SCD are either too old for a transplant or don’t have a relative who is a good enough genetic match for them to act as a donor. A well-matched donor is needed to have the best chance for a successful transplant. Source: NIH-08/20/2017

Majors FundersMt. Zion Congregational Church (Board of Mission and Outreach)Cleveland Clinic Foundation In Faith Community Foundation (George & Ola Sewell Fund)City of Cleveland /Community Development Block GrantOhio Department of HealthUnited Way Services

Major ContributorsAubrey G. NelsonUnited Way of the Greater Daytona AreaUnited Way of Tucson & Southern ArizonaMr. Kwabena AfriyieBenevityMr. & Mrs. Larry & Claudia BowmanCombined Federal CampaignWells Fargo Community Support CampaignEnterprise Rent-A-CarYour Cause (Corporate Employee Giving Program)Epsilon Lambda Omega Chapter (Ms. Allene Houston Jones)Zeta Omega ChapterUnited Way Metropolitan ChicagoCalvary Baptist ChurchPhilomethean ClubMs. Angela ColemanMs. Janice FosterLutheran Community FoundationUnited Way of Hopewell Prince GeorgeNetwork for Good Mr. Rufus Heard Enterprise Holdings, Inc.Rev. Paul H. Sadler, Jr.Cairo Elementary SchoolTruistPrayer UnlimitedDr. Mark A. WorfordAttorney Leah Williams

General DonationsAllstate Giving CampaignGreater Cleveland Community SharesUnited Way Greater Williamsburg CampaignSarah M.T. AlexanderJewyana AndersonAshley BarnesCynthia Bauknight Emma BlakeJason S. Bradley (Community Candle Co.)Mary. L BradleyMike Brooks Carolyn ButlerBrenda BurstonStacie CarterWJCC Berkeley Middle SchoolRanjani Chakraborty (Tina Brawley)Viola ColesJorge CruzGerald CunninghamEl Hasa Court No.47Tim DavisLouise DavisMark DickinsonJoseph & Marie Dula, Jr.

Tiffany EdwardsMarvis EvansSara FieldsJanice FosterKimberly FosterBernetta D. FoyTazel FranklinJasmine Xavia GreenHalburt HudsonLamont HollandGary O. JenningsAmber JohnsonDarryl C. JohnsonMervyn JonesJewell A. Jordan (ADTRA Family Reunion) Jeffery KarsonInejia Michelle LongGwendolyn LynnAlvin Manigault Jerome MarionCarolyn MasseyCandice Minter (Bill & Jackie Minter )Valarie Michele MorrisLori Mues ( Julene Drayton Monroe)LeJoyce NaylorOghogho Osayamwen Jifunza Page David M. Paris (Nurenberg-Paris)Parrish Hill Baptist ChurchMelba PritchettGeorge PurefoyRefresh Ministries International LLCNakita Reed Jim ReardonDr. Earl & Lisa SchneiderJean H. SmithGus SparksWillie SullinsAlton TinkerPatricia A. TriggsJerwon L. Turner Channelle WardBrenda WellsReginald WellsCarole Bethea-WhiteJan WhiteThomas White Laverne Whitworth Belinda WickesCharisma Williams Perdexter H. Williams Martin T. WymerMarvis Evans In Kind DonationsCrop BistroAllen Reuter (The Woodhouse Spa)Chris Mann (The Woodhouse Spa)TargetWayne GrantJoe Vigiotti (Gallucci’s Italian FoodsKevin Flynn (Massage Envy)Brian & Beth Quinn (Massage Envy)Cleveland Botanical GardensPier WCleveland Public TheatreThe Cleveland ImprovThe Ritz CarltonJohn Robert’s Spa

What is a hemoglobin electrophoresis test?A hemoglobin electrophoresis test is a blood test used to measure and identify the different types of hemoglobin in your bloodstream. Hemoglobin is the protein inside red blood cells responsible for transporting oxygen to your tissues and organs.

Genetic mutations can cause your body to produce hemoglobin that is formed incorrectly. This abnormal hemoglobin can cause too little oxygen to reach your tissues and organs.

A hemoglobin electrophoresis will indicate if there are any abnormal types of hemoglobin caused by genetic disorders such as sickle anemia.

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NatureofActivitiesandFinance

TheAmericanSickleCellAnemiaAssociation,Inc.(ASCAA)providesSickleCelltestingtoatriskpopulationsandprovideseducationalinformationtothepublicaboutSickleCelldisease. Approximately, 64%, 5%, 6%, and 25% of the ASCAA’s support for the yearendedDecember31,2016comefromallocationsfromtheOhioDepartmentofHealth,the United Way Services, and the City of Cleveland Community Development BlockGrant Program, Cleveland Clinic (in-Kind), corporate and general public donors. Asresult, ASCAA concluded the Year 2016 with a surplus of $1,389 which is better than$41,151deficitinYear2015.

6% CDBG

25% Corporate Donors &

Others

5% UW

64% ODH

Financial

Nature of Activities and FinanceThe American Sickle Cell Anemia Association, Inc. (ASCAA) provides Sickle Cell testing to at risk populations and provides educational information to the public about Sickle Cell disease. Approximately, 64%, 5%, 6%, and 25% of the ASCAA’s support for the year ended December 31, 2016 come from allocations from the Ohio Department of Health, the United Way Services, and the City of Cleveland Community Development Block Grant Program, Cleveland Clinic (in-Kind), corporate and general public donors. As result, ASCAA concluded the Year 2016 with a surplus of $1,389 which is better than $41,151 deficit in Year 2015.

What is Sickle Cell Disease?The term sickle cell disease (SCD) describes a group of inherited red blood cell disorders. People with SCD have abnormal hemoglobin, called hemoglobin S or sickle hemoglobin, in their red blood cells.Hemoglobin is a protein in red blood cells that carries oxygen throughout the body.“Inherited” means that the disease is passed by genes from parents to their children. SCD is not contagious. A person cannot catch it, like a cold or infection, from someone else.People who have SCD inherit two abnormal hemoglobin genes, one from each parent. In all forms of SCD, at least one of the two abnormal genes causes a person’s body to make hemoglobin S. When a person has two hemoglobin S genes, Hemoglobin SS, the disease is called sickle cell anemia. This is the most common and often most severe kind of SCD. Hemoglobin SC disease and hemoglobin Sβ thalassemia (thal-uh-SEE-me-uh) are two other common forms of SCD.Some Forms of Sickle Cell Disease• Hemoglobin SS• Hemoglobin SC• Hemoglobin Sβ0 thalassemia• Hemoglobin Sβ+ thalassemia• Hemoglobin SD• Hemoglobin SE

continued

Dear Friends:The American Sickle Cell Anemia Association was incorporated in 1971 as a nonprofit organization. The mission of the organization is to provide comprehensive education, testing, counseling and supportive services to the population at risk for sickle cell anemia and its variants. Further, its intent is to ensure quality and quantitative care in the provision of comprehensive service to affected individuals and families.In 2016 ASCAA’s five regional counties (Cuyahoga, Lake, Geauga, Lorain and Medina) continued to place a high emphasis on the delivery of services culturally proficient, family centered and community based. During this period more than 30,000 individual received services from ASCAA. By sustaining its community-based partnership with the Ohio Department of Health, Cleveland Clinic, United Way Services, Cleveland Community Block Grant, individual and private donors all regional programs have again received the education, testing, counseling and supportive crisis intervention services that make up our ASCAA continuum. ASCAA also continues to provide educational information requests throughout the world.On behalf of the Board and staff of the American Sickle Cell Anemia Association, we encourage you to continue supporting this organization in its efforts to eventually eliminate this chronic illness. Please visit our website and Facebook. You may also contact us with your questions and comments.Sincerely,Pamela Bradford, L.I.S.W., B.C.D., C.S.W.MBoard Chair