SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual...
-
Upload
edgar-jenkins -
Category
Documents
-
view
217 -
download
1
Transcript of SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual...
![Page 1: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/1.jpg)
SARC Business Meeting
November 2005
![Page 2: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/2.jpg)
Trial Update
• SARC 001 Gleevec– Closed to accrual– Outstanding data– Requests
• SARC 002 STS/gem-txt– Closed to accrual– Outstanding data– Requests
![Page 3: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/3.jpg)
Trial UpdateSARC 003 bone/gem-txt
• IRB/Contracts– Mayo– MDAnderson 5– NCI 3– Ortho Hosp– Penn– Univ of MI 2– Wash Cancer 1– Yale 1
• Contracts– Partners– Emory– Univ Florida
• Neither– MSKCC– Seattle– UCLA– Univ Toronto– Moffitt
![Page 4: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/4.jpg)
Trial UpdateSARC 004
• DFSP/Gleevec– University of Michigan– Seattle– Partners– MSKCC– MDAnderson
![Page 5: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/5.jpg)
Trial Update
• SARC 005– Adjuvant uterine/
gem/txt– IRB approval
pending from MSKCC
– Contracts– Database
development– GOG
• SARC 006– MPNST– DoD– Database
development
![Page 6: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/6.jpg)
• Data capture– Web based– Ongoing training for
data quality– CACR
Center for the Advancement of Clinical Research
• Michigan
• Drug distribution– Centralized pharmacy– Reputation for quality– Biologics
• North Carolina
Trial Support
![Page 7: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/7.jpg)
Location
• Rented office space– Dominos Farms
24 Frank Lloyd Wright Dr
Ann Arbor, MI
![Page 8: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/8.jpg)
Employees
• Administrative assistant– Barb Thibert
• Accountant– Keith Locke
• Research Project Manager– Emily Hollenberg, RN, MPH
![Page 9: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/9.jpg)
Finances
• Income (from inception 11/03)– $505,156
• Expenses (from inception 11/03)– $192,202
![Page 10: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/10.jpg)
Finances• Income (by category)
– Biannual meeting $ 15,000– Donations $ 20,000– Guideline Translation $ 25,000– Primary Vascular $ 4,300– Rosenfeld Symposia $ 50,000– SARC 002 $ 92,356– SARC 003 $ 40,000 ($ 78,000)– SARC 004 $ 25,000– Scientific Symposia $133,500– Website Development $100,000
$505,156
![Page 11: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/11.jpg)
Finances
• Expenses (by category)– Biannual meeting $ 17,871– Operating expenses $ 49,650– SARC 002 $ 52,332– SARC 003 $ 40,229– Scientific symposia $ 31,942– Website development $ 180
$192,202
![Page 12: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/12.jpg)
Executive Committee
• Monthly calls
• Review all trials
• Discuss protocols in development
![Page 13: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/13.jpg)
Board of Directors
• Annual Meeting– November 18,2005
![Page 14: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/14.jpg)
Development Subcommittee
• Members– Deborah Buks– David Marsh– Tim McCormick– Charles Nearberg
• Activities– Discuss strategies – Evaluate potential opportunities
![Page 15: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/15.jpg)
Eugene and MaxineRosenfeld
David Marsh
![Page 16: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/16.jpg)
The Silver Fox Club contributes 10 percent of its sales to helping those with sarcoma cancer, which has affected the founder’s wife. Out Fox Sarcoma
Paul Corliss
Ann Foote-Primary Vascular Sarcoma Fund
![Page 17: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/17.jpg)
Development
• Meeting with Dr. Doroshow
• Utilize website
• RO1 application
• Continue to explore additional funding opportunities
![Page 18: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/18.jpg)
Website Development
• Proposal from
Altum/CommonHealth
![Page 19: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/19.jpg)
Website
• Destination for sarcoma clinical trials
• Source of information – Physicians– Patients and families
• Emphasize credibility
• Call to action– Clinical trials– Support
• Link with other sites
![Page 20: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/20.jpg)
Guideline Translation
• Nancy Leahy• Laura Zyczynski• Jenni Heaton• Joan Giblin• Kelly Scheu• Linda Sohn• Monica Davey• Lauren Long• Donna Bernstein• Terri Armen• Carolyn Hayes• Denise Parker• 7 pending
![Page 21: SARC Business Meeting November 2005. Trial Update SARC 001 Gleevec –Closed to accrual –Outstanding data –Requests SARC 002 STS/gem-txt –Closed to accrual.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649ceb5503460f949b6f37/html5/thumbnails/21.jpg)
• New Business
• Future directions– Developmental therapeutics– Launch website
• Maximize – Clinical trial awareness– Education– Outreach
– Partnering