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Saliva testSaliva testtinny rasjadtinny rasjad

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Salivary glands - AnatomySalivary glands - Anatomy

Minor salivary glandsMinor salivary glandsHundreds throughoutHundreds throughout

mouthmouth

Major salivary glands (3Major salivary glands (3

on each side of face)on each side of face)Parotid Gland (chee)Parotid Gland (chee)

Su!mandi!ular glandSu!mandi!ular gland

(under angle of the ja")(under angle of the ja")

Su!lingual gland (underSu!lingual gland (under

tongue)tongue)

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Physiology and #unctionPhysiology and #unction

Saliva functionSaliva function$ontrols oral %H$ontrols oral %H

Assists "ith food intaeAssists "ith food intae

&u!ricates food !olus&u!ricates food !olus

$ontains amylase for car!ohydrate$ontains amylase for car!ohydrate

digestiondigestion

Mouth cleansing and oral hygieneMouth cleansing and oral hygiene

Saliva limits oral %athogen gro"thSaliva limits oral %athogen gro"th 'educes oral odor (halitosis)'educes oral odor (halitosis)

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Saliva contentSaliva content

ater *+,ater *+,

rganic com%ounds mucin* amylase*rganic com%ounds mucin* amylase*

lyso.ym* immunoglo!ulin Alyso.ym* immunoglo!ulin AAnorganic com%ounds H$Anorganic com%ounds H$3-3-* /* $l* 0a** /* $l* 0a*

$a* %hos%hates and others1$a* %hos%hates and others1

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A%licationA%lication

Molecular DiagnosticMolecular Diagnostic

2etection of 20A und '0A "ith molecular !iological2etection of 20A und '0A "ith molecular !iological

methodsmethods

- Head nec cancer- Head nec cancer cancer diagnosis for health carecancer diagnosis for health care

- $linical diagnostic of infections and %eriodontitis- $linical diagnostic of infections and %eriodontitis

direct detection of viral and !acterial %athogensdirect detection of viral and !acterial %athogens

Drug Detection (Drugs of Abuse)Drug Detection (Drugs of Abuse)

4he detection of narcotics e1g1 cocaine*4he detection of narcotics e1g1 cocaine*

am%hetamines and %sychotro%icam%hetamines and %sychotro%ic

current drug consumption.current drug consumption.

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A%licationA%lication

Hormones and EnzymesHormones and Enzymes

2etermination of steroid hormones* e1g12etermination of steroid hormones* e1g1

cortisol as "ell as !iogenic amines ascortisol as "ell as !iogenic amines as

melatonin from saliva can give information onmelatonin from saliva can give information on

a %erson5s current hormone statusa %erson5s current hormone status

-amylase-amylase is a %arameter to identify stressis a %arameter to identify stress

and also used for authentification of saliva inand also used for authentification of saliva inthe drug screening area1the drug screening area1

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A%licationA%lication

Clinical cemistry parametersClinical cemistry parameters 6lectrolytes as /7* Mg87* $a87* P+*6lectrolytes as /7* Mg87* $a87* P+*

li%ids as H2&*li%ids as H2&*

salivar %roteins meta!olites as al!umin*salivar %roteins meta!olites as al!umin*total %rotein and creatinine sho" goodtotal %rotein and creatinine sho" good

correlation of saliva 9 serumcorrelation of saliva 9 serum

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4esting of saliva %roduction4esting of saliva %roduction

:nstimulated %roduction collection of saliva:nstimulated %roduction collection of saliva

into container during ;< mininto container during ;< min

Stimulated %roduction collection of salivaStimulated %roduction collection of saliva

during ;< min of che"ing %arafine gumduring ;< min of che"ing %arafine gumMeasuring of !oth amounts during 8=;< minMeasuring of !oth amounts during 8=;< min

0ormal levels9 greater than >-;? ml0ormal levels9 greater than >-;? ml

Pathologic levels9 under > mlPathologic levels9 under > ml

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@erostomia@erostomia

DefinitionDefinition

2ecreased saliva %roduction2ecreased saliva %roduction

!ysiology" #ali$a plays $ital role in!ysiology" #ali$a plays $ital role indental ealtdental ealt

'e-minerali.es enamel'e-minerali.es enamel

uffers cariogenic acidsuffers cariogenic acids

'emoves food residue'emoves food residue

Bnhi!its !acterial gro"thBnhi!its !acterial gro"th

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Causes of %erostomiaCauses of %erostomia

Medications (anticholinergic affect)Medications (anticholinergic affect)

4ricyclic Antide%ressant4ricyclic Antide%ressantss

Antis%asmodicsAntis%asmodics

0eurole%tic0eurole%ticss

MA inhi!itorMA inhi!itorss

Anti%arinsonian agentsAnti%arinsonian agents

&ithium&ithium

$entral Adrenergic Agonist$entral Adrenergic Agonists (antihy%ertensives)s (antihy%ertensives)

2iuretics2iuretics

2econgestant2econgestantss

AntihistamineAntihistaminess

ronchodilatorronchodilatorss

http://www.fpnotebook.com/PSY193.htmhttp://www.fpnotebook.com/PSY193.htmhttp://www.fpnotebook.com/PSY205.htmhttp://www.fpnotebook.com/PSY205.htmhttp://www.fpnotebook.com/PSY187.htmhttp://www.fpnotebook.com/PSY187.htmhttp://www.fpnotebook.com/PSY171.htmhttp://www.fpnotebook.com/PSY171.htmhttp://www.fpnotebook.com/CV217.htmhttp://www.fpnotebook.com/CV217.htmhttp://www.fpnotebook.com/CV232.htmhttp://www.fpnotebook.com/CV232.htmhttp://www.fpnotebook.com/ENT166.htmhttp://www.fpnotebook.com/ENT166.htmhttp://www.fpnotebook.com/ENT144.htmhttp://www.fpnotebook.com/ENT144.htmhttp://www.fpnotebook.com/LUN127.htmhttp://www.fpnotebook.com/LUN127.htmhttp://www.fpnotebook.com/LUN127.htmhttp://www.fpnotebook.com/ENT144.htmhttp://www.fpnotebook.com/ENT166.htmhttp://www.fpnotebook.com/CV232.htmhttp://www.fpnotebook.com/CV217.htmhttp://www.fpnotebook.com/PSY171.htmhttp://www.fpnotebook.com/PSY187.htmhttp://www.fpnotebook.com/PSY205.htmhttp://www.fpnotebook.com/PSY193.htm

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ther causesther causes

'adiation thera%y to head and nec'adiation thera%y to head and nec

Salivary GlandSalivary Glandsurgerysurgery

Sjogren5s SyndromeSjogren5s Syndrome

AmyloidosisAmyloidosisHuman Bmmunodeficiency CirusHuman Bmmunodeficiency Cirus((HBC BnfectionHBC Bnfection))

2ia!etes Mellitus2ia!etes Mellitus

Major 2e%ressionMajor 2e%ression

Granulomatous 2iseaseGranulomatous 2isease SarcoidosisSarcoidosis

4u!erculosis4u!erculosis

&e%rosy&e%rosy

http://www.fpnotebook.com/ENT58.htmhttp://www.fpnotebook.com/ENT58.htmhttp://www.fpnotebook.com/RHE26.htmhttp://www.fpnotebook.com/RHE26.htmhttp://www.fpnotebook.com/RHE16.htmhttp://www.fpnotebook.com/RHE16.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/END11.htmhttp://www.fpnotebook.com/END11.htmhttp://www.fpnotebook.com/PSY63.htmhttp://www.fpnotebook.com/PSY63.htmhttp://www.fpnotebook.com/LUN93.htmhttp://www.fpnotebook.com/LUN93.htmhttp://www.fpnotebook.com/LUN188.htmhttp://www.fpnotebook.com/LUN188.htmhttp://www.fpnotebook.com/ID3.htmhttp://www.fpnotebook.com/ID3.htmhttp://www.fpnotebook.com/ID3.htmhttp://www.fpnotebook.com/LUN188.htmhttp://www.fpnotebook.com/LUN93.htmhttp://www.fpnotebook.com/PSY63.htmhttp://www.fpnotebook.com/END11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/RHE16.htmhttp://www.fpnotebook.com/RHE26.htmhttp://www.fpnotebook.com/ENT58.htm

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Stomatitis and locali.ed oral lesionsStomatitis and locali.ed oral lesionsA%hthous :lcersA%hthous :lcers

ral chemical !urnsral chemical !urns

ral su%%urative lesionsral su%%urative lesions

Alveolar a!scessAlveolar a!scess

6%ulis6%ulis ral infectious &esionsral infectious &esions

2ental $aries2ental $aries

2i%htheria2i%htheria

Sy%hilisSy%hilis

4u!erculosis4u!erculosisSmall Po=Small Po=

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Acute viral sialadenitisAcute viral sialadenitis

Parotitis acutaParotitis acuta

Paramy=ovirusParamy=ovirus

0eurotro%hic effect n1CBBB0eurotro%hic effect n1CBBBAffection of gonadal tissues* %ancreas*Affection of gonadal tissues* %ancreas*

central nervous systEmcentral nervous systEm

Bncu!ation9 ;> daysBncu!ation9 ;> dayshole life immunityhole life immunity

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Acute !acterial sialadenitisAcute !acterial sialadenitis

Ascendent ductal infectionAscendent ductal infection

2ehydratation* dia!etes* renal diseases*2ehydratation* dia!etes* renal diseases*

"rong dental hygiene* inflammation in"rong dental hygiene* inflammation in

mouth and %haryn=mouth and %haryn=

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$hronic !acterial %arotitis$hronic !acterial %arotitis

Predis%osition ectasy of salivary ducts Predis%osition ectasy of salivary ducts

congenital* %ostinfectious* o!structive*congenital* %ostinfectious* o!structive*

immuno%atologicalimmuno%atological

Sialogra%hySialogra%hy

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SialolithiasisSialolithiasis

Stones com%osed of $a salts often o!structStones com%osed of $a salts often o!struct

salivary glands* causing %ain* s"elling* andsalivary glands* causing %ain* s"elling* and

sometimes infection1 2iagnosis is made clinicallysometimes infection1 2iagnosis is made clinically

or "ith $4* ultrasound* or sialogram1 4reatmentor "ith $4* ultrasound* or sialogram1 4reatmentinvolves stone e=%ression "ith saliva stimulants*involves stone e=%ression "ith saliva stimulants*

manual mani%ulation* a %ro!e* or surgery1manual mani%ulation* a %ro!e* or surgery1

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