Robotikk innen kirurgi Hva skjer nå og i fremtiden? · Peter F. Nichol is chief medical officer,...
Transcript of Robotikk innen kirurgi Hva skjer nå og i fremtiden? · Peter F. Nichol is chief medical officer,...
ThomasLangøPhD,ChiefScientist,MedicalTechnology,SINTEF,Trondheim
Coordinator@NorwegianNationalAdvisoryUnitforUltrasoundandImage-GuidedTherapy,St.Olavshospital,ResearchUnit
RobotikkinnenkirurgiHvaskjernåogifremtiden?
Disclaimer• Nocommercialbindings
• OneSINTEF-projectrunning:
• CollaborationMedTechandMathematics&CyberneticsatSINTEFandNTNU.Noindustrypartners.FundedbytheResearchCouncilofNorway.Focusoncombiningnonlinearstateestimationtechniqueswithmachinelearningmethodstoestimateandpredictthemotionofmovingobjectsbasedoninputfromdifferentsensors,suchas3Dcamerasandultrasoundprobes,andusingthistoenableroboticarmstointeractwiththeobjectsthroughdynamicinteractioncontrol.Themethodswillbetestedonusecasesfrombothindustryandmedicine,andinthelattercasethefocuswillbeonautomatedultrasoundexaminationswithoutanyintervention.
• PreviousstrategicSINTEFprojectsatMedTechgrouptoinetgraterobotarm(UR5)withtheCustusXplatform.
• Onemajorpublicationonroboticsinsurgery:
• SzoldA,LangøT,BergamaschiR,LutzS,BroedersIAMJ,DankelmanJ,ForgioneA,MelzerA,MintzY,MoralesS,RhodesM,TreglohanJ,SatavaR,Chung-ngaiT,VilallongaR.EAES(EuropeanAssociationofEndoscopicSurgeons)ConsensusStatementontheUseofRoboticsinGeneralSurgery.SurgEndosc,2015,Feb;29(2):253-288.
• (Morethanaverageinterestindevelopingusefultechnologyfordiagnosticsandinterventions)
Arobotisamachine—especiallyoneprogrammablebyacomputer—capableofcarryingoutacomplexseriesofactionsautomatically
Robot
Mechatronics
Roboticsforsurgery,not…foreverythingelse
Evolutionofsurgery-towardsrobotics
Briefhistory
• 1985:PUMA560,needleforabrainbiopsyusingCT
• 1988:Samerobotfortransurethralresection
• 1988:PROBOT(ImperialCollege)prostaticsurgery
• 1992:ROBODOCfromIntegratedSurgicalSystems:
• milloutfittingsinthefemurforhipreplacement
• 2000-1:
• ComputerMotionwiththeAESOP
• ZEUSRoboticSurgicalSystems
• IntuitiveSurgical,daVinciSurgicalSystem
Puma560,1985 PROBOT,1988
ROBODOC,1992
AESOP,1994
Robotsforsurgery
ArtemisEberhardKarlsUniversity
RoboticSurgicalSimulator(RoSS)SimulatedSurgicalSystemsLLC,2009
CardioArmsGrifantini,2008
Orthopilot(2001,FDA)
TheRIO™RoboticArmInteractiveOrthopedicSystem(MAKOSurgicalCorp)
ZeusRoboticSurgicalSystemComputerMotion,Inc.FDA2001
SRI’sM7TelesurgicalRobotDLRMIRO
NeuroMate SofieSurgicalRobot
TheNavioPFSRoboticSurgicalSystemBlueBeltTech
Surgical‘robot’vendors
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• Accuray• AesyntInc• AVRASurgicalRobotics• CambridgeMedicalRobotics• IMRIS• IRobot• Johnson&Johnson• KirbyLester• MAZORRobotics• Medrobotics• MedTech• Medtronic• NovaTractSurgical• Olympus• OmniGuideHoldings• Smith&Nephew• Stereotaxis• TransEnterix• VerbSurgical• VerilyLifeSciences
IntuitiveSurgical(daVinci)VerbSurgicalMedtronicTINAVIMedicalTechnologiesAKTORmedGmbHROBOTICSurgeryAurisSurgicalRoboticsStrykerTitanMedicalBrainLAB…
Technologyforabettersociety
2µm
• mindrereisingforpasientene• desentraliseringavhelsetjenester• egentligfjernstyringavenarmsomholderproben• tohjernerogfirehendersomstyrerettapparat…
•AutonomousUSimaging•TeleoperatedUSimaging•Human-robotcooperation
robot-assisted US imaging
Robot-assistedUSimaging
13
Robotsandpeopleworktogetherinthefutureworkplaces
Roboticsurgery,Robotically-assistedsurgery,Mechatronics,Mechanicaltele-manipulator,…
daVincisurgicalsystem
CompetitiontodaVinciisemerging
Senhance™SurgicalRoboticSystem
-laparoscopiccolorectalandlaparoscopicgynecologicsurgery
FDAin2017
CompetitiontodaVinciisemerging
Flex®RoboticSystemforScarfree™ColorectalProcedures
FDAin2017
CompetitiontodaVinciisemerging
SPORTSurgicalSystem
FDA:2019anticipated
-broadapplicationsofsingleandmulti-quadrantsurgeriespreviouslynotpossiblewithcurrentroboticsolutions
daVinciinuse
• 200.000surgeriesconductedin2012,mostcommonlyforhysterectomiesandprostateremovals
• 2016fiscalyear;IntuitiveSurgicalreportedrevenueof$670million
• Roboticsurgerygenerallycostsanywherefrom$3.000to$6.000morethantraditionallaparoscopicsurgery
• “Withinfiveyears,oneinthreeU.S.surgeries—morethandoublecurrentlevels—isexpectedtobeperformedwithroboticsystems,”(Fortunemagazine,2016)
• In2016:3.803unitsworldwide–2.501inUSA,644inEurope,476inAsia,and182intherestoftheworld(http://phx.corporate-ir.net/phoenix.zhtml?c=122359&p=irol-faq)
https://en.wikipedia.org/wiki/Da_Vinci_Surgical_System
• ECRIInstitute(nonprofitorganization)analyzedmorethan4.000studiesonroboticsurgery:
• evidenceisn’tstrongenoughtodetermineifarobotisbetterthantraditionalminimallyinvasivesurgery
• evidenceindicatesthatit’sbettercomparedtoopensurgery
daVinciinuse
“ThedaVincirobot-assistedsurgerydeviceisasolutioninsearchofaproblem—butonehellofamarketingmachine”
Roboticsinsurgery
• Thereisnohigh-qualityevidencetoinformthecomparativeeffectivenessofLRPorRARPcomparedtoORPforoncologicaloutcomes.Urinaryandsexualqualityoflife-relatedoutcomesappearsimilar.
• Overallandseriouspostoperativecomplicationratesappearsimilar.Thedifferenceinpostoperativepainmaybeminimal.MenundergoingLRPorRARPmayhaveashorterhospitalstayandreceivefewerbloodtransfusions.Allavailableoutcomedatawereshort-term,andthisstudywasunabletoaccountforsurgeonvolumeorexperience.
Robotic-AssistedvsLaparoscopicRadicalNephrectomy
• Theproportionofradicalnephrectomiesusingrobotic-assistedoperationsincreasedfrom1.5%in2003to27.0%in2015
• Althoughtherewasnosignificantdifferencebetweenrobotic-assistedvslaparoscopicradicalnephrectomyinmajorpostoperativecomplications,robotic-assistedprocedureswereassociatedwithlongeroperatingtimeandhigherdirecthospitalcosts.
JAMA.2017;318(16):1561-1568.doi:10.1001/jama.2017.14586
Robotic-AssistedvsConventionalLaparoscopicSurgeryonRiskofConversiontoOpenLaparotomyAmongPatientsUndergoingResectionforRectalCancer
• Amongpatientswithrectaladenocarcinomasuitableforcurativeresection,robotic-assistedlaparoscopicsurgery,ascomparedwithconventionallaparoscopicsurgery,didnotsignificantlyreducetheriskofconversiontoopenlaparotomy.
• Thesefindingssuggestthatrobotic-assistedlaparoscopicsurgery,whenperformedbysurgeonswithvaryingexperiencewithroboticsurgery,doesnotconferanadvantageinrectalcancerresection.
JAMA.2017;318(16):1569-1580.doi:10.1001/jama.2017.7219
PossibleadvantagesofRoboticsurgery• Shorterhospitalization
• Reducedpainanddiscomfort
• Fasterrecoverytimeandreturntonormalactivities
• Smallerincisions,resultinginreducedriskofinfection
• Reducedbloodlossandtransfusions
• Minimalscarring
• Advantagesforsurgeonsusingroboticsurgeryinclude:
• Greatervisualization
• Enhanceddexterity,nofulcrumeffect
• Greaterprecision
• Surgeoncansit,lessrestraining
• Handtremorsfiltered,scaledmotion
PossibledisadvantagesofRoboticsurgery• Longeroperatingtime
• Learningcurve
• Lackofstudiesonlongtermresults
• Costs-1.8millUSDanddisposables2.000USDperprocedure
• Noconsistentprotocolstoproperlydeterminewhichpatientsarethebestcandidatesforthevariousroboticprocedures
• Arcing;electricalcurrentsleakoutofthedeviceduringsurgerycausingsparks
• Disdvantagesforsurgeons/researchersusingroboticsurgeryinclude:
• Immobileandweighsmorethanhalfatonne
• Proprietarysoftware
• Madeforremotetelesurgery(awayfrompatient)
• (Almost)nohapticfeedback(forceofinstruments)
• Non-ergonomicneckandtrunkangle(armrestheighthasalimitedadjustmentrange)
• =>Increasedcognitiveload
Intuitiveisadefendantinapproximately50lawsuitsallegingproductliability
Roboticsinsurgery-othercriticalviews…• Robotintroducedin2000.Unlikethecellphone,ithasnotevolvedintoabetter,sleekertechnologyand
itisn’tcheaper.
• Therobotrepresentsanattempttoaddresstheergonomiccrisisinsurgery(forsurgeons)?
• Iftherewereanadvantageinprecisionorgettingintosmallspaces,itwouldshowupinthedata?
• Intherapidlyevolvingenvironmentofvalue-basedmedicine(outcomepercost)therobotloses…
• Hospitalspayannualsix-figuremaintenancefee.Aftertenyears,theinitialcostofthepurchasehasdoubled!
• Reprocessingarobot:approx.of4.5hoursoflabor.Usuallymore.• mostgoodreprocessingtechscanturnoverinstrumentsfor13ORsinthesametimeittakestoreprocessoneroboticcaseinoneOR
• Instrumentamortization.Breakanarmoranattachment,add$40Ktoyoursix-figurebillfortheyear.Incontrast,ahigh-qualitylaparoscopicinstrumentwillcostaround$1Ktoreplace.
PeterF.Nicholischiefmedicalofficer,MedawareSystems
VisualizationinMIS
Robotics in medicine Integrating Surgical Systems for Autonomy in the future OR
“Penelope” – robotic scrub nurseMichael Treat MD, Columbia Univ, NYC. 2003
da VinciSurgical master-slave “robot” system
FromtraditionalsurgerytosmallerproceduresoutsidetheOR
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Futureofroboticsurgery-tailoredinstruments
http://microsure.nl
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Futureofroboticsurgery-tailoredinstruments
CambridgeMedicalRoboticsVersiussystemcapabilitytooperateacrossallfoursurgicalquadrants,allowingittobeusedingynaecology,urology,upperGIandcolorectalsurgery
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Electromechanicaltool HumanExtensions,Israel
Futureofroboticsurgery-automaticcameracontrol AutoLap,Israel
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Futureof‘robotic’surgery-tailoredinstruments
http://www.laparasurgical.com
Therapyfromwithintubes-Flexibleendoscopy
•Cardiacsurgery•GIsurgery(endoluminalsurgery)•Gynaecology•Urology•ENT•Neurosurgery•Vascularsurgery(endovascular)
Flexibleplatforms-Mainchallenge…
Madefordiagnosis,notsurgery
April2nd,2007,Marescauxetal,IRCAD
Flexibleplatforms-Instrumentplatform
EndoSAMURAI,Olympus
Roboticflexibleendoscopyplatformsindevelopment
NeoGuidesystem
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Singleincisionroboticplatforms
SurgiBot
SpiderSurgery
VirtualIncision
Flexibleplatforms-Instrumentplatform
Medrobotics,FlexRoboticsSystem,FDAclearedJuly2015
Robot-AssistedEndovascularCatheterization
RAFII-TARIetal.CurrentandEmergingRobot-AssistedEndovascularCatheterizationTechnologies:AReview.AnnalsofBiomedicalEngineering,Vol.42,No.4,April2014(Ó2013)pp.697–715
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Futureofroboticsurgery Magellanroboticsystem,HansenMedical
Futureofroboticsurgery-Opensource
Opensourceplatform
TheRavensystem
TheRavenisanopen-architecturesurgicalrobotforlaparoscopicsurgeryresearchfromAppliedDexterity.Ithastwocable-driven7DOFarms(6DOF+grasp).Itisintendedtofacilitatecollaborativeresearchonadvancesinsurgicalrobot
Futureofroboticsurgery http://bionics.seas.ucla.edu
RobotassistedproceduresinMIT
Courtesy:AØstvik,SINTEF/NTNU,EHofstad,SINTEF
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Cognitiverobotics
http://www.zividlabs.com
Accuratereal-time3Dcolorcamera
KunstigintelligensDyplæring
Maskinlæring
USguidedFUS
CourtesyAMenciassi,Pisa,www.futuraproject.eu
Futureofroboticsurgery TwenteUniv.,TheNetherlands
Futureofroboticsurgery TwenteUniv.,TheNetherlands
FromtraditionalsurgerytosmallerproceduresoutsidetheOR
Nanoroboticist Metin Sitti shows the tiny robot that cantake pictures, biopsy, and deliver medicine inside of you
http://nanolab.me.cmu.edu/projects/capsules/SoftMagneticCapsule.shtml
www.vector-project.com
GII2015 GlobalInnovation
Index(GII)isanannualrankingofcountriesbytheircapacityfor,andsuccessin,innovation
GII2017 GlobalInnovation
Index(GII)isanannualrankingofcountriesbytheircapacityfor,andsuccessin,innovation
Røros
Technology for a better society
Technologyforabettersociety