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Robert I. Grossman, M.D. Curriculum Vitae Page 23 159. Boorstein JM, Wong KT, Grossman RI, Bolinger L, McGowan JC. Metastatic lesions of the brain: imaging with magnetization transfer. Radiology 1994;191(3):799-803. 160. Grossman RI, Gomori JM, Ramer KN, Lexa FJ, Schnall MD. Magnetization transfer: theory and clinical applications in neuroradiology. Radiographies 1994; 14(2):279-290. 161. Lexa FJ, Grossman RI. MR of sarcoidosis in the head and spine: spectrum of manifestations and radiographic response to steroid therapy. AJNR Am J Neuroradiol 1994;15(5):973-982. 162. Cortey A, Jarvik JG, Lenldnski RE, Grossman RI, Frank I, Delivoria-Papadopoulos M. Proton MR spectroscopy of brain abnormalities in neonates born to HIV-positive mothers. AJNR Am J NeuroradioI 1994;15(10):1853-1859. 163. Mittl R_L, Grossman RI, Hiehle JF, Hurst RW, Kauder DR, Gennarelli TA, Alburger GW. Prevalence of MR evidence of diffuse axonal injul3, in patients with mild head injm'y and normal head CT findings. AJNR Am J Neuroradiol 1994;15(8):1583-1589. 164. Hiehle JF, Jr., Lenkinski RE, Grossman RI, Dousset V, Ramer KN, Schnall MD, Cohen JA, Gonzalez-Searano F. Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis. Magn Reson Med 1994;32(3):285-293. 165. Campellone JV, Kolson DL, Wells GB, Grossman RI. Cerebral infarction during hypertensive encephalopathy: Case report with pathologic and atypical radiographic fmdings. J Stroke Cerebrovasc Dis 1995;5:66-71. 166. Jarvik JG, Philips GR, 3rd, Schwab CW, Schwartz JS, Grossman RI. Penetrating neck trauma: sensitivity of clinical examination and cost-effectiveness of angiography. AJNR Am J Neuroradiol 1995; 16(4):647-654. 167. Loevner LA, Grossman RI, McGowan JC, Ramer KN, Cohen JA. Characterization of multiple sclerosis plaques with Tl-weighted MR and quantitative magnetization transfer. AJNR Am J Neuroradiol 1995;16(7):1473-1479. 168. Loevner LA, Grossman R_I, Cohen JA, Lexa FJ, Kessler D, Kolson DL. Microscopic disease in normal-appearing white matter on conventional MR images in patients with multiple sclerosis: assessment with magnetization-transfer measurements. Radiology 1995;196(2):511- 515. 169. Turetsky B, Cowell PE, Gur RC, Grossman ILl, Shtasel DL, Gur RE. Frontal and temporal lobe brain volumes in schizophrenia. Relationship to symptoms and clinical subtype. ka'ch Gen Psychiatry 1995;52(12): 1061-1070. 170. Wong KT, Grossman RI, Boorstein JM, Lexa FJ, McGowan JC. Magnetization transfer imaging ofperiventricular hypelSntense white matter in the elderly. AJNR Am J Neuroradiol 1995;16(2):253-258. 171. Hiehle JF, Jr., Grossman RI, Ramer KN, Gonzalez-Scarano F, Cohen JA. Magnetization transfer effects in MR-detected multiple sclerosis lesions: comparison with gadolinium-enhanced spin-echo images and nonenhanced Tl-weighted images. AJNR Am J Neuroradiol 1995;16(1):69-77.

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159. Boorstein JM, Wong KT, Grossman RI, Bolinger L, McGowan JC. Metastatic lesions ofthe brain: imaging with magnetization transfer. Radiology 1994;191(3):799-803.

160. Grossman RI, Gomori JM, Ramer KN, Lexa FJ, Schnall MD. Magnetization transfer:theory and clinical applications in neuroradiology. Radiographies 1994; 14(2):279-290.

161. Lexa FJ, Grossman RI. MR of sarcoidosis in the head and spine: spectrum ofmanifestations and radiographic response to steroid therapy. AJNR Am J Neuroradiol1994;15(5):973-982.

162. Cortey A, Jarvik JG, Lenldnski RE, Grossman RI, Frank I, Delivoria-Papadopoulos M.Proton MR spectroscopy of brain abnormalities in neonates born to HIV-positive mothers. AJNRAm J NeuroradioI 1994;15(10):1853-1859.

163. Mittl R_L, Grossman RI, Hiehle JF, Hurst RW, Kauder DR, Gennarelli TA, Alburger GW.Prevalence of MR evidence of diffuse axonal injul3, in patients with mild head injm'y and normalhead CT findings. AJNR Am J Neuroradiol 1994;15(8):1583-1589.

164. Hiehle JF, Jr., Lenkinski RE, Grossman RI, Dousset V, Ramer KN, Schnall MD, CohenJA, Gonzalez-Searano F. Correlation of spectroscopy and magnetization transfer imaging in theevaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis.Magn Reson Med 1994;32(3):285-293.

165. Campellone JV, Kolson DL, Wells GB, Grossman RI. Cerebral infarction duringhypertensive encephalopathy: Case report with pathologic and atypical radiographic fmdings. JStroke Cerebrovasc Dis 1995;5:66-71.

166. Jarvik JG, Philips GR, 3rd, Schwab CW, Schwartz JS, Grossman RI. Penetrating necktrauma: sensitivity of clinical examination and cost-effectiveness of angiography. AJNR Am JNeuroradiol 1995; 16(4):647-654.

167. Loevner LA, Grossman RI, McGowan JC, Ramer KN, Cohen JA. Characterization ofmultiple sclerosis plaques with Tl-weighted MR and quantitative magnetization transfer. AJNRAm J Neuroradiol 1995;16(7):1473-1479.

168. Loevner LA, Grossman R_I, Cohen JA, Lexa FJ, Kessler D, Kolson DL. Microscopicdisease in normal-appearing white matter on conventional MR images in patients with multiplesclerosis: assessment with magnetization-transfer measurements. Radiology 1995;196(2):511-515.

169. Turetsky B, Cowell PE, Gur RC, Grossman ILl, Shtasel DL, Gur RE. Frontal andtemporal lobe brain volumes in schizophrenia. Relationship to symptoms and clinical subtype.ka'ch Gen Psychiatry 1995;52(12): 1061-1070.

170. Wong KT, Grossman RI, Boorstein JM, Lexa FJ, McGowan JC. Magnetization transferimaging ofperiventricular hypelSntense white matter in the elderly. AJNR Am J Neuroradiol1995;16(2):253-258.

171. Hiehle JF, Jr., Grossman RI, Ramer KN, Gonzalez-Scarano F, Cohen JA. Magnetizationtransfer effects in MR-detected multiple sclerosis lesions: comparison with gadolinium-enhancedspin-echo images and nonenhanced Tl-weighted images. AJNR Am J Neuroradiol1995;16(1):69-77.

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172. Boorstein JM, Titelbaum DS, Patel Y, Wong KT, Grossman RI. CT diagnosis ofunsuspected traumatic cataracts in patients with complicated eye injuries: significance ofattenuation value of the lens. AJR Am J Roentgenol 1995;164(1): 181-184.

173. Sinson G, Zager EL, Grossman R!, Germarelli TA, Flamm ES. Cavernous malformationsof the third ventricle. Neurosurgely 1995;37(1):37-42.

174. Keiper MD, Ng SE, Atlas SW, Grossman RI. Subcortical hemorrhage: marker forradiographically occult cerebral vein thrombosis on CT. J Comput Assist Tomogr1995;19(4):527-531.

175. Constantinescu CS, Grossman RI, Finelli PF, Kamoun M, Zmijewski C, Cohen JA.Clinical and subclinical neurological involvement in children of conjugal multiple sclerosispatients. Mult Scler 1995; 1 (3): 170-172.

176. Udupa J-K, Samarasekera S, Miki Y, Grossman RI. Detection mad quantification of MSlesions using fuzzy topological principles. Proc SPIE Medical Imaging 1996;2710:81-9 I.

177. Kundel H, Redfem R, Langlotz CP, Grossman RI, Brikman I, Horii SC, Feingold E,Nodine CF. Workflow in a nem'oradiology reading room using multiviewers. Proe SPIE MedicalImaging 1996;2711:232-235.

178. Hirsch JA, Langlotz CP, Lee J, Tanio CP, Grossman RI, Schulman KA. Clinicalassessment of MR of the brain in nonsm'gical inpatients. AJNR Am J Neuroradiol1996; 17(7): 1245-1253.

179. Listerud J, Mitchell J, Bagley L, Orossman R. OIL FLAIR: optimized interleaved fluid-attenuated inversion recovery in 2D fast spin echo. Magn Reson Med 1996;36(2):320-325.

180. Kimura H, Meaney DF, McGowan JC, Grossman RI, Lenkinsld RE, Ross DT, McIntoshTK, Gennarelli TA, Smith DH. Magnetization transfer imaging of diffuse axonal injuryfollowing experimental brain injury in the pig: characterization by magnetization transfer ratiowith histopathologic correlation. J Comput Assist Tomogr 1996;20(4):540-546.

181. Petrella JR, Grossman RI, McGowan JC, Campbell G, Cohen JA. Multiple sclerosislesions: relationship between MR enhancement pattern and magnetization transfer effect. AJNRAm J Neuroradiol 1996; 17(6): 1041-1049.

182. Hirsch JA, Lenkinski RE, G-rossman RI. MR spectroscopy in the evaluation of enhancinglesions in the brain in multiple sclerosis. AJNR Am J Neuroradiol 1996;17(10): 1829-1836.

183. Loevner LA, Shapiro RM, Grossman R!, Overhauser J, Kamholz J. White matter changesassociated with deIetions of the long arm of chromosome 18 (18q- syndrome): a dysmyelinatingdisorder? AJNR Am J Neuroradiol 1996;17(10):1843-1848.

184. Cooney BS, (3rossman RI, Farber RE, Goin JE, Galetta SL. Frequency of magneticresonance imaging abnormalities in patients with migraine. Headache 1996;36(10):616-621.

185. van Buchem MA, McGowan JC, Kolson DL, Polansky M, Grossman RI. Quantitativevolumetric magnetization transfer analysis in multiple sclerosis: estimation of macroscopic andmicroscopic disease but'den. Magn Reson Med 1996;36(4):632-636.

186. Grossman R_t, Modic MT. A randomized comparison of iodixanol and iohexol in adultintraeranial computed tomography scanning. Acad Radiol 1996;3 Suppl 3:$488-494.

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187. Kimura H, Grossman RI, Lenkinski RE, Gonzalez-Scarano F. Proton MR spectroscopyand magnetization transfer ratio in multiple sclerosis: correlative findings of active versusirreversible plaque disease. AJNR Am J Neuroradiol 1996; 17(8): 1539-1547.

188. Udupa JK, Wei L, Miki Y, Grossman RI. System for the comprehensive analysis ofmultiple sclerosis lesion load based on MR imagery. Proc SPIE Medical Imaging1997;3031:610-618.

189. Miki Y, Grossman R!, Udupa JK, Samarasekera S, van Buchem MA, Cooney BS,Pollack SN, Kolson DL, Constantinescu C, Polansky M, Marmon LJ. Computer-assistedquantitation of enhancing lesions in multiple sclerosis: correlation with clinical c!assification.AJNR Am J Neuroradiol 1997;18(4)'705-710.

190. van Buchem MA, Udupa JK, McGowan JC, Mild Y, Heyning FH, Boncoeur-Malÿel MP,Kolson DL, Polansky M, Grossman RI. Global volumetric estimation of disease burden inmultiple sclerosis based on magnetization transfer imaging. AJNR Am J Neuroradiol1997; 18(7): 1287-1290.

191. Constantinescu CS, Goodman DB, Grossman RI, Marmon LJ, Cohen JA. Serumangiotensin-converting enzyme in multiple sclerosis. Arch Neurol 1997;54 (8): 1012-1015.

192. Kasner SE, Galetta SL, McGowan JC, Grossman RI. Magnetization transfer imaging inprogressive multifoeal leukoencephalopathy. Neurology 1997;48(2):534-536.

193. Bagley LJ, Grossman RI, Judy KD, Curtis M, Loevner LA, Polansky M, Detre J.Gliomas: correlation of magnetic susceptibility artifact with histologic grade. Radiology1997;202(2):511-516.

194. Samm'asekera S, Udupa JK, Miki Y, Wei L, Grossman RI. A new computer-assistedmethod for the quantification of enhancing lesions in multiple sclerosis. J Comput Assist Tomogr1997;21(1): 145-151.

195. Keiper MD, Grossman RI, Brtmson JC, Schnall MD. The low sensitivity of fluid-attenuated inversion-recovery MR in the detection of multiple sclerosis of the spinal cord. AJNRAm J Neuroradiol 1997;18(6):1035-1039.

196. Udupa JK, Wei L, Samarasekera S, Miki Y, van Buchem MA, Crrossman RI. Multiplesclerosis lesion quantification using fuzzy-connectedness principles. IEEE Trans Med Imaging1997; 16(5):598-609.

197. Stecker MM, Hirsch JA, Crrossman RI, Hurst RW. Timing and laterality of strokesassociated with cardiac operations. J Neurovascular Disease 1998;3:203-218.

198. Filippi M, Horsfield MA, Ader HJ, Barkhof F, Bruzzi P, Evans A, Frank JA, GrossmanRI, McFarland HF, Molyneux P, Paty DW, Simon J, Toffs PS, Wolinsky JS, Miller DH.Guidelines for using quantitative measures of brain magnetic resonance imaging abnormalities inmonitoring the treatment of multiple sclerosis. Ann Neurol 1998;43(4):499-506.

199. Grossman RI, McGowan JC. Perspectives on multiple sclerosis. AJNR Am J NeuroradioI1998;19(7):1251-1265.

200. Lieberman AP, Grossman RI, Lavi E. Case of the month: April 1997--a 32 year old manwith mental status changes and a severe occipital headache. Brain Pathol 1998;8(1):229-230.

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20I. Miller DH, Grossman RI, Reingold SC, McFarland H_F. The role ofmagnetic resonancetechniques in understanding and managing multiple sclerosis. Brain 1998;121 (Pt 1):3-24.

202. van Buehem MA, Grossman RI, Armstrong C, Polansky M, Mild Y, Heyning FH,Boncoeur-Martel MP, Wei L, Udupa JK, Grossman M, Kolson DL, McGowan JC. Correlation ofvolumetric magnetization transfer imaging with clinical data in MS. Neurology1998;50(6): 1609-1617.

203. Phillips MD, G-rossman RI, Mild Y, Wei L, Kolson DL, van Buchem MA, Polansky M,McGowan JC, Udupa JK. Comparison of T2 lesion volume and magnetization transfer ratiohistogram analysis and of atrophy and measures of lesion burden in patients with multiplesclerosis. AJNR Am J Neuroradiol 1998; 19(6): 1055-1060.

204. Mild Y, Grossman RI, Udupa JK, Wei L, Kolson DL, Mannon LJ, Grossman M. IsolatedU-fiber involvement in MS: preliminary observations. Neurology 1998;50(5):1301-1306.

205. Barkhof F, McGowan JC, van Waesberghe JH, Grossman RI. Hypointense multiplesclerosis lesions on Tl-weighted spin echo magnetic resonance images: their contribution inunderstanding multiple sclerosis evolution. J Neurol Neurosurg Psychiatry 1998;64 Suppl 1 :$77-79.

206. McGowan JC, Filippi M, Campi A, Grossman RI. Magnetisation transfer imaging: theoryand application to multiple sclerosis. J Neurol Neurosurg Psychiatry 1998;64 SuppI 1 :$66-69.

207. Cecil KM, Hills EC, Sandel ME, Smith DH, MeIntosh TK, Mannon LJ, Sinson GP,Bagley L J, Grossman RI, Lenkinski RE. Proton magnetic resonance spectroscopy for detectionof axonal injury in the splenium of the corpus callosum of brain-injured patients. J Neurosurg1998; 88(5):795-801.

208. Gonen O, Viswanathan AK, Catalaa I, Babb J, Udupa J, Crrossman RI. Total brain N-acetylaspatÿate concentration in normal, age-grouped females: quantitation with non-echo protonNMR spectroscopy. Magn Reson IVied 1998;40(5):684-689.

209. Roychowdhury S, Maldjian JA, Oaletta SL, Grossman R/. Postanoxic encephalopathy:diffusion MR fmdings. J Comput Assist Tomogr 1998;22(6):992-994.

210. Keiper MD, Grossman RI, Hirsch JA, Bolinger L, Ott IL, Mannon LJ, Langlotz CP,Kolson DL. MR identification of white matter abnormalities in multiple sclerosis: a comparisonbetween 1.5 T and 4 T. AJNR Am J Neuroradiol 1998;19(8):1489-1493.

211. I-Ih'sch JA, Loevner LA, Yousem DM, Siegelman ES, Keiper MD, Marquis RP,Grossman RI. Gadolinium-erthanced fat-suppressed Tl-weighted imaging of the head and neck:comparison of gradient and conventional SE sequences. J Comput Assist Tomogr1998 ;22(5): 771-776.

212. Bagley LJ, Grossman RI, McGowan J C. Magnetization transfer contrast: its utility as atechnique and its application to central nervous system pathology. Neurology 1999;53(5 Suppl3):$49-51.

2 i3. Ga'ossman RI. Application of magnetization transfer imaging to multiple sclerosis.Neurology 1999.;53(5 Suppl 3):$8-11.

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214. van Buchem MA, McGowan JC, Ga'ossman RI. Magnetization transfer histogrammethodology: its clinical and neuropsychological correlates. Neurology 1999;53(5 Suppl 3):$23-28.

215. Fulton JC, Grossman RI, Mannon LJ, Udupa J, Kolson DL. Familial multiple sclerosis:volumetric assessment in clinically symptomatic and asymptomatic individuals. Mult Scler1999;5(2):74-77.

216. McGowan JC, McColrnack TM, C-a'ossman RI, Mendonca R, Chen XH, Berlin JA,Meaney DF, Xu BN, Cecil KM, McIntosh TK, Smith DH. Diffuse axonal pathology detectedwith magnetization transfer imaging following brain injury in the pig. Magn Reson Med1999;41(4):727-733.

217. Fazekas F, BarkhofF, Filippi M, Grossman RI, Li DK, McDonald WI, McFarland HF,Paty DW, Simon JH, Wolinsky JS, MilIer DH. The contribution of magnetic resonance imagingto the diagnosis of multiple sclerosis. Neurology 1999;53(3):448-456.

218. Rostami AM, Sater RA, Bird SJ, Galetta S, Farber RE, Kamoun M, Silberberg DH,Grossman RI, Pfohl D. A double-blind, placebo-c0ntrolied trial of extracorporeal photopheresisin chronic progTessive multiple sclerosis. Mult Scler 1999;5(3):198-203.

219. Bagley LJ, Grossman RI, Galetta SL, Sinson GP, Kotapka M, McGowan JC.Characterization of white matter lesions in multiple sclerosis and traumatic brain injury asrevealed by magnetization transfer contour plots. AJNR Am J Neuroradiol 1999;20(6):977-981.

220. Miki Y, Grossman RI, Udupa JK, van Buchem MA, Wei L, Phillips MD, Patel U,McGowan JC, Kolson DL. Differences between relapsing-remitting and chronic progressivemultiple sclerosis as detelÿnined with quantitative MR imaging. Radiology 1999;210(3):769-774.

221. Miki Y, Grossman RI, Udupa JK, Wei L, Polansky M, Mannon LJ, Kolson DL.Relapsing-remitting multiple sclerosis: longitudinal analysis of MR images--lack of correlationbetween changes in T2 lesion volume and clinical findings. Radiology 1999;213(2):395-399.

222. Fulton JC, Grossman RI, Udupa J, Mannon LJ, Grossman M, Wei L, Polansky M,Kolson DL. MR lesion load and cognitive function in patients with relapsing-remitting multiplesclerosis. AJNR Am J Neuroradiol 1999;20(10):1951-1955.

223. Patel UJ, Grossman RI, Phillips MD, Udupa JK, McGowan JC, Miki Y, Wei L, PolanskyM, van Buehem MA, Kolson D. Serial analysis of magnetization-transfer histograms andExpanded Disability Status Scale scores in patients with relapsing-remitting multiple sclerosis.AJNR Am J Neuroradiol 1999;20(10):1946-1950.

224. Catalaa I, Fulton JC, Zhang X, Udupa JK, Kolson D, Grossman M, Wei L, McGowan JC,Polansky M, Grossman RI. MR imaging quantitation of gray matter involvement in multiplesclerosis and its correlation with disability measures and neurocognitive testing. AJNR Am JNeuroradiol 1999;20(9):1613-1618.

225. Liu AY, Maldjian JA, Bagley LJ, Sinson GP, Grossman RI. Traumatic brain injury:diffusion-weighted MR imaging findings. AJNR Am J Neuroradiol 1999;20(9): 1636-1641.

226. Pelak VS, Galetta SL, Grossman RI, Townsend JJ, Volpe NJ. Evidence for preganglionicpupillary involvement in superficial siderosis. Neurology 1999;53(5):1130-1132.

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227. Hurst RW, Grossman RI. Peripheral spinal cord hypointensity on T2-weighted MRimages: a reliable imaging sign of venous hypertensive myelopathy. AJNR Am J Neuroradiol2000;21 (4): 781-786.

228. Gur RE, Cowell PE, Latshaw A, Turetsky BI, Grossman RI, Arnold SE, Bilker WB, GurRC. Reduced dorsal and orbital prefrontal gray matter volumes in schizophrenia. Arch GenPsychiatry 2000;57(8):761-768.

229. Gur RE, Turetsky BI, CowelI PE, Finkelman C, Maany V, Grossman RI, Arnold SE,Bilker WB, Gur RC. Temporolimbic volume reductions in schizophrenia. Arch Gen Psychiatry2000;57(8): 769-775.

230. Catalaa I, Grossman RI, Kolson DL, Udupa JK, Nyul LG, Wei L, Zhang X, Polansky M,Mannon LJ, McGowan JC. Multiple sclerosis: magnetization transfer histogram analysis ofsegmented normal-appearing white matter. Radiology 2000;216(2):351-355.

231. Gonen O, Grossman RI. The accuracy of whole brain N-acetylaspartate quantification.Magn Reson Imaging 2000;18(10):1255-1258.

232. Ge Y, Grossman RI, Udupa JK, Fulton J, Constantinescu CS, Gonzales-Scarano F, BabbJS, Mannon LJ, Kolson DL, Cohen JA. Glatiramer acetate (Copaxone) treatment in relapsing-remitting MS: quantitative MR assessment. Neurology 2000;54(4):813-817.

233. Bagley LJ, McGowan JC, Grossman RI, Sinson G, Kotapka M, Lexa FJ, Berlin JA,McIntosh TK. Magnetization transfer imaging of traumatic brain injury. J Magn Reson Imaging2000;11(1):1-8.

234. GrossmanRI. Brain imaging. AJNRAm JNeuroradio12000;21(1):9-18.

235. Gonen O, Catalaa I, Babb JS, Ge Y, Mannon LJ, KolsonDL, Grossman RI. Total brainN-acetylaspartate: a new measure of disease load in MS. Neurology 2000;54(1): 15-19.

236. Gass A, Filippi M, Grossman RI. The contribution of MRI in the differential diagnosis ofposterior fossa damage. J Neurol Sci 2000;172 Suppl 1:S43-49.

237. Grossman R_I, Barkhof F, Filippi M. Assessment of spinal cord damage in MS usingMR!. J Neurol Sci 2000;172 Suppl I:$36-39.

238. Grossman RI, Kappos L, Wolinsky JS. The contribution of magnetic resonance imagingin the differential diagnosis of the damage of the cerebral hemispheres. J Neurol 8ci 2000;172Suppl 1:$57-62.

239. Yousry TA, Grossman RI, Filippi M. Assessment of posterior fossa damage in MS usingMRI. J Neurol 8ci 2000;172 Suppl 1:850-53.

240. Grossman RI, Rubin DL, Hunter G, Haughton VM, Lee D, Sze G, Kuhn MJ, MaravillaK, Tu R, Heindel W, Wippold FJ, 2nd, Leeds N, Zelch J, Jinkins JR, Grodd W, Truwit C, KanalE, Provenzale JM, Ramsey R, Simon J, Brunberg JA, Stevens GR, Kristy RM. Magneticresonance imaging in patients with central nelwous system pathology: a comparison ofOptiMARK (Gd-DTPA-BMEA) and Magnevist (Gd-DTPA). Invest Radio12000;35(7):412-419.

241. Saindane AM, Ge Y, Udupa JK, Babb JS, Mannon LJ, Grossman RI. The effect ofgadolinium-enhancing lesions on whole brain atrophy in relapsing-remitting MS. Neurology2000;55(1):61-65.

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242. Galetta SL, Grossman RI. The representation of the horizontal meridian in the primaryvisual cortex. J Neuroophthalmol 2000;20(2):89-91.

243. Kaiser JS, Grossman RI, Polansky M, Udupa JK, Mild Y, Galetta SL. Magnetizationtransfer histogram analysis of monosymptomatic episodes of neurologic dysfunction:preliminary findings. AJNR Am J Neuroradio12000;21 (6): 1043-1047.

244. Maki DD, Crrossman RI. Patterns of disease spread in metastatic breast carcinoma:influence of estrogen and progesterone receptor status, AJNR Am J Neuroradiol2000;21 (6):1064-1066.

245. Ge Y, Grossman RI, Udupa J-K, Wei L, Mannon LJ, Polansky M, Kolson DL. Brainatrophy in relapsing-remitting mttltiple sclerosis and secondary progressive multiple sclerosis:longitudinal quantitative analysis. Radiology 2000;214(3):665-670.

246. McGowan JC, Yang JI-I, Plotkin RC, Grossman RI, Umile EM, Cecil KM, Bagley LJ.Magnetization transfer imaging in the detection of injury associated with mild head trauma.AJNR Am J Neuroradio12000;21(5):875-880.

247. Roychowdhury S, Maldjian JA, Grossman RI. Multiple sclerosis: comparison of traceapparent diffusion coefficients with MR enhancement pattern of lesions. AJNR Am JNeuroradio12000;21 (5):869-874.

248. Ge Y, Udupa JK, Nyul LG, Wei L, Grossman RI. Numerical tissue characterization inMS via standardization of the MR image intensity scale. J Magn Reson Imaging 2000;12(5):715-721.

249. Nisenbaum HL, Bimbaum BA, Myers MM, Grossman R_I, Gefter WB, Langlotz CP. Thecosts of CT procedures in an academic radiology department determined by an activity-basedcosting (ABC) method. J Comput Assist Tomogn" 2000;24(5):813-823.

250. Moriarty DM, Li BS, He J, Markowitz CE, Grossman RI, Gonen O. Whole-brain N-acetylaspartate magnetic resonance spectroscopy: a potential marker for treatment decisions inrelapsing-remitting MS. Cuardernos de Esclerosis Multiple 2001 ;10:15-25.

251. He J, Grossman RI, Ge Y, Mannon LJ. Enhancing patterns in multiple sclerosis:evolution and persistence. AJNR Am J Neuroradio12001 ;22(4):664-669.

252. Sinson G, Bagley LJ, Cecil KM, Torchia M, McGowan JC, Lenkinski RE, McIntosh TK,Grossman RI. Magnetization transfer imaging and proton MR spectroscopy in the evaluation ofaxonal injury: correlation witla clinical outcome atter traumatic brain injm% AJNR Am JNeuroradio12001 ;22(I): 143-151.

253. Ge Y, Crrossman RI, Udupa JK, Babb JS, Kolson DL, McGowan JC. Magnetizationtransfer ratio histogram analysis of gray matter in relapsing-remitting multiple sclerosis. AJNRAm J Neuroradio12001;22(3):470-475.

254. Maldjian JA, Grossman RI. Future applications of DWI in MS. J Neurol Sci 2001;186Suppl 1:855-57.

255. Harttmg HP, Grossman RI. ADEM: distinct disease or part ofthe MS spectrum?Neurology 2001 ;56(10): 1257-1260.

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256. Udupa JK, Nyul LG, Ge Y, Grossman RI. Multiprotocol MR image segmentation inmultiple sclerosis: experience with over 1,000 studies. Acad Radio12001;8(11):I 116-1126.

257. Ge Y, Grossman RI, Udupa JK, Babb JS, Nyul LG, Kolson DL. Brain atrophy inrelapsing-remitting multiple sclerosis: fractional volumetric analysis of gray matter and whitematter. Radiology 2001 ;220(3):606-610.

258. Patel SH, Kolson DL, Glosser G, Matozzo I, Ge Y, Babb JS, Mannon LJ, Grossman RI.Correlation between percentage of brain parenchymal volume and neurocognitive performancein HIV-infeeted patients. AJNR Am J Neuroradio12002;23(4):543-549.

259. Filippi M, Grossman RI. MRI techniques to monitor MS evolution: the present and thefuture. Neurology 2002;58(8):1147-1153.

260. Ge Y, Grossman RI, Udupa JK, Babb JS, Mannon LJ, McGowan JC. Magnetizationtransfer ratio histogram analysis of normal-appearing gray matter and normal-appearing whitematter in multiple sclerosis. J Comput Assist Tomogr 2002;26(1):62-68.

261. Bonneville F, Moriarty DM, Li BS, Babb JS, Grossman R_I, Gonen O. Whole-brain N-acetylaspartate concentration: correlation with T2-weighted lesion volume and expandeddisability status scale score in cases of relapsing-remitting multiple sclerosis. AJNR Am JNeuroradiol 2002;23(3):371-375.

262. Filippi M, Dousset V, McFarland I-W, Miller DH, Grossman RI. Role of magneticresonance imaging in the diagnosis and monitoring of multiple sclerosis: consensus report of theWhite Matter Study Group. J Magn Reson Imaging 2002;15(5):499-504.

263. Wolf RL, Imbesi SG, Galetta SL, Hurst RW, Sinson GP, Grossman RI. Development of aposterior cerebral artery anemrysm subsequent to occlusion of the contralateral internal carotidartery for giant cavernous anetuysm. Neuroradiology 2002;44(5):443-446.

264. MacKenzie JD, Siddiqi F, Babb JS, Bagley LJ, Mannon LJ, Sinson GP, Grossman RI.Brain atrophy in mild or moderate traumatic brain injury: a longitudinal quantitative analysis.AJNR Am J Neuroradio12002;23(9):1509-1515.

265. Paulson HL, Garbem JY, Hoban TF, Krajewski KM, Lewis RA, Fischbeck KH,Grossman RI, Lenkinski R, Kamholz JA, Shy ME. Transient central nervous system whitematter abnormality in X-linked Charcot-Marie-Tooth disease. Ann Neurol 2002;52(4):429-434.

266. Gonen O, Moriarty DM, Li BS, Babb JS, He J, Listerud J, Jacobs D, Markowitz CE,Grossman RI. Relapsing-remitting multiple sclerosis and whole-brain N-acetylaspartatemeasurement: evidence for different clinical cohorts initial observations. Radiology2002;225 (1):261-268.

267. Ge Y, Grossman RI, Babb JS, Rabin ML, Marmon LJ, Kolson DL. Age-related total graymatter and white matter changes in normal adult brain. Part I: volumetric MR imaging analysis.AJNR Am J Neuroradio12002;23(8):1327-1333.

268. Ge Y, Grossman RI, Babb JS, Rabin ML, Mannon LJ, Kolson DL. Age-related total graymatter and white matter changes in normal adult brain. Part II: quantitative magnetizationtransfer ratio histogram analysis. AJNR Am J Neuroradio12002;23(8): I334-1341.

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269. Bonneville F, Grossman RI. [Quid? Ossification of the posterior common vertebralligament]. J Radio12003;84(12 Pt 1):1991-1993.

270. Filippi M, Bozzali M, Rovaris M, Gonen O, Kesavadas C, Ghezzi A, Mmÿtinelli V,Grossman RI, Scotti G, Comi G, Falini A. Evidence for widespread axonal damage at the earliestclinical stage of multiple sclerosis. Brain 2003;126(Pt 2):433-437.

271. Ge Y, KolsonDL, Babb JS, MarmonLJ, GrossmanRI. Whole brain imaging of HIV-infected patients: quantitative analysis of magnetization transfer ratio histogram and fractionalbrain volume. AJNR Am J Nem'oradio12003 ;24(1):82-87.

272. Li BS, Regal J, Soher BJ, Mannon LJ, Grossman RI, Gonen O. Brain metabolite profilesof Tl-hypointense lesions in relapsing-remitting multiple sclerosis. AJNR Am J Neuroradiol2003;24(1):68-74.

273. Inglese M, Li BS, Rusinek H, Babb JS, Grossman RI, Gonen O. Diffusely elevatedcerebral choline and creatine in relapsing-remitting multiple sclerosis. Magn Reson Med2003 ;50(1): 190-195.

274. Ge Y, Grossman RI, Babb JS, He J, Mannon LJ. Dirty-appearing white matter in multiplesclerosis: volumetric MR imaging and magnetization transfer ratio histogram analysis. AJNRAm J Neuroradio12003;24(10):1935-1940.

275. Patel SH, Inglese M, Glosser G, Kolson DL, Grossman RI, Gonen O. Whole-brain N-acetylaspartate level and cognitive performance in HIV infection. AJNR Am J Neuroradiol2003 ;24(8): 1587-1591.

276. Frohman EM, Goodin DS, Calabresi PA, Corboy JR, Coyle PK, Filippi M, Frank JA,Galetta SL, Grossman R_t, Hawker K, Kachuck NJ, Levin MC, Phillips JT, Raeke MK, RiveraVM, Smart WH. The utility of MRI in suspected MS: report of the Therapeutics and TechnologyAssessment Subcommittee of the American Academy of Neurology. Neurology 2003;61 (5):602-611.

277. Inglese M, Ge Y, Filippi M, Falini A, Grossman RI, Gonen O. Indirect evidence for earlywidespread gray matter involvement in relapsing-remitting multiple sclerosis. Neuroimage2004;21(4): 1825-1829.

278. Ge Y, Gonen O, Inglese M, Babb JS, Markowitz CE, Grossman RI. Nem'onal cell injuryprecedes brain atrophy in multiple sclerosis. Neurology 2004;62(4):624-627.

279. Ge Y, Law M, Johnson G, Herbert J, Babb JS, Marmon LJ, Grossman RI. Preferentialoccult injury of corpus callosum in multiple sclerosis measured by diffusion tensor imaging. JMagn Reson Imaging 2004;20(1): 1-7.

280. Lu S, Aim D, Johnson G, Law M, Zagzag D, Grossman RI. Diffusion-tensor MR imagingof intracranial neoplasia and associated peritumoral edema: introduction of the tumor infiltrationindex. Radiology 2004;232(1 ):221-228.

281. Inglese M, Liu S, Babb JS, Mannon LJ, G-rossman RI, Gonen O. Three-dimensionalproton spectroscopy of deep gray matter nuclei in relapsing-remitting MS. Neurology2004 ;63(1 ): 170-172.

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282. Law M, Saindane AM, Ge Y, Babb JS, Johnson G, Mannon LJ, Herbert J, Grossman RI.Mierovascular abnormality in relapsing-remitting multiple sclerosis: perfusion MR imagingfindings in normal-appearing white matter. Radiology 2004;231(3):645-652.

283. Ge Y, Law M, Grossman RI. Applications of diffusion tensor MR imaging in multiplesclerosis. Annals ofthe New York Academy of Sciences 2005;1064:202-219.

284. Inglese M, Bomsztyk E, Gonen O, Mannon LJ, Grossman RI, Rusinek H. Dilatedperivascular spaces: hallmarks of mild traumatic brain injury. AJNR Am J Neuroradiol2005 ;26(4): 719-724.

285. Inglese M, Makani S, Johnson G, Cohen BA, Silver JA, Gonen O, Grossman RI. Diffuseaxonal injury in mild traumatic brain injury: a diffusion tensor imaging study. J Neurosurg2005; 103(2):298-303.

286. He J, Inglese M, Li BS, Babb JS, Grossman RI, Gonen O. Relapsing-remitting multiplesclerosis: metabolic abnormality in nonenhancing lesions and normal-appearing white matter atMR imaging: initial experience. Radiology 2005;234(1 ):211-217.

287. Ge Y, Law M, Johnson G, Herbert J, Babb JS, Mannon LJ, Grossman RI. Dynamicsusceptibility contrast perfusion MR imaging of multiple sclerosis lesions: characterizinghemodynamic impairment and inflammatory activity. AJNR Am J NeuroradioI 2005 ;26(6): 1539-1547.

288. Ge Y, Law M, Herbert J, G-rossman RI. Prominent perivenular spaces in multiplesclerosis as a sign ofperivascular inflammation in pfirnary demyelination. AJNR Am JNeuroradiol 2005;26(9):2316-2319.

289. Inglese M, Grossman RI, Filippi M. Magnetic Resonance Imaging Monitoring ofMultiple Sclerosis Lesion Evolution. J Neuroimaging 2005;15(4 suppl):22S-29.

290. Inglese M, Grossman RI, Diller L, Babb JS, Gonen O, Silver JM, Rusinek H. Clinicalsignificance of dilated Virchow-Robin spaces in mild traumatic brain injury. Brain Inj2006;20(1):I5-21.

291. Orbach DB, Pramanik BK, Lee J, Maldonado TS, Riles T, Grossman RI. Carotid arterystent implantation: evaluation with multi-detector row CT angiography and virtual angioscopy--initial experience. Radiology 2006;238(1 ):309-320.

292. Hesseltine SM, Law M, Babb J, Rad M, Lopez S, Ge Y, Johnson G, Grossman RI.Diffusion tensor imaging in multiple sclerosis: assessment of regional differences in the axialplane within normal-appearing cervical spinal cord. AJNR Am J Neuroradiol 2006;27(6):1189-1193.

293. Lee R.F, Johnson G, Grossman RI, Stoeckel B, TrampeI R, McGuinness G. Advantagesof parallel imaging in conjunction with hypelÿpolarized helium--a new approach to MRI of thelung. Magn Reson Med 2006;55(5):1132-1141.

294. Adhya S, Johnson G, Herbert J, Jaggi H, Babb JS, Grossman RI, Inglese M. Pattem ofhemodynamic impailrnent in multiple sclerosis: Dynamic susceptibility contrast perfusion MRimaging at 3.0 T. Neuroimage 2006.