RNA interference (RNAi) [aka post-transcriptional gene silencing (PTGS)]

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RNA interference (RNAi) [aka post-transcriptional gene silencing (PTGS)]. - PowerPoint PPT Presentation

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“RNA interference not only promises to explain biological mysteries, but is also turning out to be a powerful research tool and a potential new source of medical breakthroughs. Like so much of biology these days, this is a story of migraine-inducing complexity.”

U.S. News and World Report, March 3, 2003

RNA interference (RNAi) [aka post-transcriptional gene silencing (PTGS)]

Page 11: RNA interference (RNAi) [aka post-transcriptional gene silencing (PTGS)]

From Nature 418:244

Page 12: RNA interference (RNAi) [aka post-transcriptional gene silencing (PTGS)]

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Quality control: nonsense-mediated decay


HOST DEFENSE AGAINST VIRUS INFECTION OF …bhillman/comparative_virology/PlantHost... · • Post transcriptional gene silencing (PTGS) or RNA interference (RNAi) represents a sequence

HOST DEFENSE AGAINST VIRUS INFECTION OF …bhillman/comparative_virology/PlantHost... · • Post transcriptional gene silencing (PTGS) or RNA interference (RNAi) represents a sequence

RNAi-mediated down-regulation of SHATTERPROOF gene in ... · Keywords BnSHP gene Gene silencing Oilseed rape RNAi Pod shattering Introduction Oilseed rape (Brassica napus L.) is the

RNAi-mediated down-regulation of SHATTERPROOF gene in ... · Keywords BnSHP gene Gene silencing Oilseed rape RNAi Pod shattering Introduction Oilseed rape (Brassica napus L.) is the

Bbhu.ac.in/science/botany/syllabi/M. Sc. Botany final vrs... · Web viewGene silencing: RNA interference (RNAi), mechanism of post-transcriptional gene silencing, importance of hairpin

Bbhu.ac.in/science/botany/syllabi/M. Sc. Botany final vrs... · Web viewGene silencing: RNA interference (RNAi), mechanism of post-transcriptional gene silencing, importance of hairpin

RNA Interference: Biology, Mechanism, and Applications · PTGS in Plants In plants, the RNA silencing story unfolded serendipitously during a search for transgenic petunia flowers

RNA Interference: Biology, Mechanism, and Applications · PTGS in Plants In plants, the RNA silencing story unfolded serendipitously during a search for transgenic petunia flowers

HC-Pro Suppression of Transgene Silencing Eliminates the ...Site of HC-Pro Action in Suppression of PTGS 573 control plants (Figure 2, lane 7), whereas high levels accu-mulated in

HC-Pro Suppression of Transgene Silencing Eliminates the ...Site of HC-Pro Action in Suppression of PTGS 573 control plants (Figure 2, lane 7), whereas high levels accu-mulated in

1st COST iPLANTA CONFERENCE CREATING A PLANT RNAI … · RNA silencing, suppressor, endogenous, ABCE1, AtRLI2 RNA silencing is a sequence-specific mechanism regulating the gene expression

1st COST iPLANTA CONFERENCE CREATING A PLANT RNAI … · RNA silencing, suppressor, endogenous, ABCE1, AtRLI2 RNA silencing is a sequence-specific mechanism regulating the gene expression

Post-Transcriptional Gene Silencing (PTGS)

Post-Transcriptional Gene Silencing (PTGS)

RNAi. What is RNAi? RNA-based mechanisms of gene silencing. These siRNAs are bound by a protein-RNA complex called the RNA-induced silencing complex (RISC)

RNAi. What is RNAi? RNA-based mechanisms of gene silencing. These siRNAs are bound by a protein-RNA complex called the RNA-induced silencing complex (RISC)

Role of Antisense and RNAi-based Gene Silencing in Crop Improvement

Role of Antisense and RNAi-based Gene Silencing in Crop Improvement

A Paragenetic Perspective on Integration of RNA Silencing into …symposium.cshlp.org/content/71/481.full.pdf · 2008-10-27 · distinct from antisense silencing. Sense-RNAi occurs

A Paragenetic Perspective on Integration of RNA Silencing into …symposium.cshlp.org/content/71/481.full.pdf · 2008-10-27 · distinct from antisense silencing. Sense-RNAi occurs

Part I: Ribozymes Part II: SELEX (RNA in-vitro evolution) Part III: RNAi RNA inhibition and silencing Prof. F.Allain 2/2/2004.

Part I: Ribozymes Part II: SELEX (RNA in-vitro evolution) Part III: RNAi RNA inhibition and silencing Prof. F.Allain 2/2/2004.

RNA interference (RNAi) - webconferences.com · RNA interference (RNAi) Natasha Caplen Gene Silencing Section Office of Science and Technology Partnerships Office of the Director

RNA interference (RNAi) - webconferences.com · RNA interference (RNAi) Natasha Caplen Gene Silencing Section Office of Science and Technology Partnerships Office of the Director

Post-transcriptional Gene Silencing (PTGS) - · PPT file · Web view · 2012-01-03Post-Transcriptional Gene Silencing (PTGS) Also called RNA interference or RNAi Process results

Post-transcriptional Gene Silencing (PTGS) - · PPT file · Web view · 2012-01-03Post-Transcriptional Gene Silencing (PTGS) Also called RNA interference or RNAi Process results

VIGS as a post transcriptional gene silencing …€¦ · Web viewGene silencing at post transcriptional level, post transcriptional gene silencing (PTGS), is an RNA-mediated systemic

VIGS as a post transcriptional gene silencing …€¦ · Web viewGene silencing at post transcriptional level, post transcriptional gene silencing (PTGS), is an RNA-mediated systemic

RNA Interference: Biology, Mechanism, and Applicationsrna-interference.yolasite.com/resources/RNAi - Biology... · 2012-02-26 · RNA silencing is a novel gene regulatory mechanism

RNA Interference: Biology, Mechanism, and Applicationsrna-interference.yolasite.com/resources/RNAi - Biology... · 2012-02-26 · RNA silencing is a novel gene regulatory mechanism

Ac45 silencing mediated by AAV‐sh‐Ac45‐RNAi prevents both ...

Ac45 silencing mediated by AAV‐sh‐Ac45‐RNAi prevents both ...

Research Article Running Head: RDR6-RdDM Functions to ... · provide a link between post-transcriptional gene silencing (PTGS) / RNAi mediated by RDR6-dependent 21-22 nt siRNAs, and

Research Article Running Head: RDR6-RdDM Functions to ... · provide a link between post-transcriptional gene silencing (PTGS) / RNAi mediated by RDR6-dependent 21-22 nt siRNAs, and

Selection and validation of optimal siRNA target sites for RNAi-mediated gene silencing

Selection and validation of optimal siRNA target sites for RNAi-mediated gene silencing

Role of antisense RNAi in gene silencing in crop

Role of antisense RNAi in gene silencing in crop

Reversal of siRNA-mediated gene silencing in vivo.download.xuebalib.com/2tl19IEAcHBz.pdf · RNA interference (RNAi) activity in vivo with short, synthetic, high-affinity oligonucleotides

Reversal of siRNA-mediated gene silencing in vivo.download.xuebalib.com/2tl19IEAcHBz.pdf · RNA interference (RNAi) activity in vivo with short, synthetic, high-affinity oligonucleotides