Review: Cells of the Immune System
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Transcript of Review: Cells of the Immune System
Review: Cells of the Immune SystemLeukocytes
Myelocytes Lymphocytes
From Larsson and Karlsson (2005)
Organs of the Immune System
Primary and secondary lymphoid organs:
Thymus
Organs of the Immune System
Bone Marrow
Organs of the Immune System
Lymphatic system
Organs of the Immune System
Organs of the Immune System
Lymphatic vessels
Organs of the Immune SystemLymph nodes
Organs of the Immune System
Spleen
Organs of the Immune SystemMucosa-Associated Lymphoid Tissue (MALT)•bronchus-associated lymphoid tissue (BALT)•gut-associated lymphoid tissue (GALT)
Organs of the Immune SystemM cells and production of immunolglobulin
Innate and Adaptive Immunity
Innate
1st line of defense
Non-specific mechanisms
Phagocytes and recognition molecules
Adaptive
2nd line of defense
Highly specific mechanisms
Lymphocytes, antigen specific
receptors, antibodies
Innate Immunity
Anatomical Barriers: skin and epithelia
Overview:
InnateImmune Response
Overview:
InnateImmune Response
Overview:
InnateImmune Response
Overview:
InnateImmune Response
Overview:
InnateImmune Response
Overview:
InnateImmune Response
InflammationRecruitment from the bloodstream
InflammationPhagocytosis of a bacterium
Inflammation
Soluble Molecules•Mannose-binding lectin (MBL)
•Proinflammatory cytokines
•Antimicrobial peptides
•Acute phase response (APR) and acute phase response proteins•complement proteins•C-reactive proteins (CRP)