Research Leaders: Meeting the challenge Mark Walport 19 November 2008.
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Transcript of Research Leaders: Meeting the challenge Mark Walport 19 November 2008.
Research Leaders:Meeting the challenge
Mark Walport
19 November 2008
Wealth matters
All cardiovascular disease deaths
• people & ideas
• teams
• major programmes
• networks
Research for health
A focus on people
• establishment of one of the largest prospective cohorts of SCD patients in East Africa (1200 patients)
• infrastructure development for diagnostics and training
• determination of the causes of morbidity and mortality amongst SCD patients
• development of locally relevant policies for management of malaria, bacterial infections and stroke in the context of SCD
Julie Makani, Research Training Fellowship
University of Tanzania
Training and capacity building
Sickle cell disease
+ Highly subsidised clinics social marketing
Noor et al., 2007. PLoS Medicine, 4(8): e255
New solutions neededResearch into practice: Insecticide treated bed nets for Malaria
With thanks to Robert Snow
• researchers in 21 countries
• whole genome association study of severe malaria
• multicentre study of immune gene polymorphisms that determine antibody production to malaria antigens
• malaria candidate gene diversity project
• identify novel malaria resistance loci by genetic linkage analysis
Networks
• Malaria Atlas Project (MAP)
• funded for five years by the Wellcome Trust and is a joint project between the Centre for Geographic Medicine, Kenya and the University of Oxford with collaborating nodes in America and Asia Pacific region
• a detailed model of the spatial limits of Plasmodium falciparum and P. vivax malaria at a global scale
Robert Snow
University of Oxford
New tools
Mapping disease
• Partnership between UK Department for International Development and Wellcome Trust
• Plus International Development Research Centre, Canada: track record strengthening health systems in Africa and a financial contribution to the project
• Kenya and Malawi (£10 million each country)
• National Task Forces developed programmes of work over a 6-month period
• Mechanism: foster and nurture National research grant-giving bodies, the Consortium for National Health Research, Kenya and the National Research Council of Malawi
• Implementation from February 2008
Capacity building: National Networks
Health Research Capacity Strengthening Initiative
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Institutional capacity building
Distribution of applicants invited for full application involving:
• institutions in 20 African countries
• collaborations with 27 non-African institutions
Awards to be made in December 2008
Global collaboration
Pandemic influenza• consortium of organisations, including:
• Bill & Melinda Gates Foundation• Institut Pasteur• National Institutes of Health• WHO• Chinese Center for Disease Control & Prevention • Wellcome Trust
• facilitate and coordinate the development of a research agenda related to human influenza:
• What is being done?• What needs to be done? • Three areas to be mapped – vaccines, drug
therapies, epidemiology/surveillance
• developing, maintaining and disseminating a central inventory of funded research activities on influenza
Health and wealth
UK France