Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic...

7
Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G. Mulle, Valerie M. Schaibley, Ryan L. Ragland, Sandra G. Durkin, Stephen T. Warren, Thomas W. Glover The American Journal of Human Genetics Volume 84, Issue 3, Pages 339-350 (March 2009) DOI: 10.1016/j.ajhg.2009.01.024 Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Transcript of Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic...

Page 1: Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G.

Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants 

Martin F. Arlt, Jennifer G. Mulle, Valerie M. Schaibley, Ryan L. Ragland, Sandra G. Durkin, Stephen T. Warren, Thomas W. Glover  

The American Journal of Human Genetics Volume 84, Issue 3, Pages 339-350 (March 2009)

DOI: 10.1016/j.ajhg.2009.01.024

Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Page 2: Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G.

Figure 1

The American Journal of Human Genetics 2009 84, 339-350DOI: (10.1016/j.ajhg.2009.01.024) Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Page 3: Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G.

Figure 2

The American Journal of Human Genetics 2009 84, 339-350DOI: (10.1016/j.ajhg.2009.01.024) Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Page 4: Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G.

Figure 3

The American Journal of Human Genetics 2009 84, 339-350DOI: (10.1016/j.ajhg.2009.01.024) Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Page 5: Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G.

Figure 4

The American Journal of Human Genetics 2009 84, 339-350DOI: (10.1016/j.ajhg.2009.01.024) Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Page 6: Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G.

Figure 5

The American Journal of Human Genetics 2009 84, 339-350DOI: (10.1016/j.ajhg.2009.01.024) Copyright © 2009 The American Society of Human Genetics Terms and Conditions

Page 7: Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants Martin F. Arlt, Jennifer G.

Figure 6

The American Journal of Human Genetics 2009 84, 339-350DOI: (10.1016/j.ajhg.2009.01.024) Copyright © 2009 The American Society of Human Genetics Terms and Conditions