Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology...

37
Remote monitoring of renal replacement treatments Pierre Simon Société Française de Télémédecine (French Society of Telemedicine) ANJH Paris 20 mai 2019 1

Transcript of Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology...

Page 1: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Remote monitoring of renal

replacement treatmentsPierre Simon

Socieacuteteacute Franccedilaise de Teacuteleacutemeacutedecine (French Society of Telemedicine)

ANJH Paris 20 mai 2019

1

The transformation of the health system in the 21st century2

ANJH Paris 20 mai 2019

Life expectancy

at birth in the

world during the

20th century

ANJH Paris 20 mai 2019

3

3

The number of persons aged over 65 years in 2050

the global burden of ageingSource US Bureau of the Census (2000)

ANJH Paris 20 mai 2019

4

ANJH Paris 20 mai 2019

5

Kalid N Zaidan AA Zaidan BB Salman OH Hashim M Muzammil HBased Real Time Remote Health Monitoring Systems A Review on Patients Prioritization and

Related Big Data Using Body Sensors information and Communication Technology

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

5

Health Expenditures

Growth

due to chronic diseases

in the USA

Health expenditures growth per capita

in Western Europe

Finland

France

Germany

Italy

Netherlands

Sweden

United Kingdom

EU members

before May 2004

Denmark

OMS 2011

6

ANJH Paris 20 mai 2019

6

The tools of e-Health to the 21st century

Telemedicine

Mobile Health IoT

Medical Artificial Intelligence

Internet 2000

Smartphone 2007

IBM Watson 2014

GAFAM BATX

ANJH Paris 20 mai 2019

7

Big Data

New medical organizations DocHome

ANJH Paris 20 mai 2019

8

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 2: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

The transformation of the health system in the 21st century2

ANJH Paris 20 mai 2019

Life expectancy

at birth in the

world during the

20th century

ANJH Paris 20 mai 2019

3

3

The number of persons aged over 65 years in 2050

the global burden of ageingSource US Bureau of the Census (2000)

ANJH Paris 20 mai 2019

4

ANJH Paris 20 mai 2019

5

Kalid N Zaidan AA Zaidan BB Salman OH Hashim M Muzammil HBased Real Time Remote Health Monitoring Systems A Review on Patients Prioritization and

Related Big Data Using Body Sensors information and Communication Technology

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

5

Health Expenditures

Growth

due to chronic diseases

in the USA

Health expenditures growth per capita

in Western Europe

Finland

France

Germany

Italy

Netherlands

Sweden

United Kingdom

EU members

before May 2004

Denmark

OMS 2011

6

ANJH Paris 20 mai 2019

6

The tools of e-Health to the 21st century

Telemedicine

Mobile Health IoT

Medical Artificial Intelligence

Internet 2000

Smartphone 2007

IBM Watson 2014

GAFAM BATX

ANJH Paris 20 mai 2019

7

Big Data

New medical organizations DocHome

ANJH Paris 20 mai 2019

8

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 3: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Life expectancy

at birth in the

world during the

20th century

ANJH Paris 20 mai 2019

3

3

The number of persons aged over 65 years in 2050

the global burden of ageingSource US Bureau of the Census (2000)

ANJH Paris 20 mai 2019

4

ANJH Paris 20 mai 2019

5

Kalid N Zaidan AA Zaidan BB Salman OH Hashim M Muzammil HBased Real Time Remote Health Monitoring Systems A Review on Patients Prioritization and

Related Big Data Using Body Sensors information and Communication Technology

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

5

Health Expenditures

Growth

due to chronic diseases

in the USA

Health expenditures growth per capita

in Western Europe

Finland

France

Germany

Italy

Netherlands

Sweden

United Kingdom

EU members

before May 2004

Denmark

OMS 2011

6

ANJH Paris 20 mai 2019

6

The tools of e-Health to the 21st century

Telemedicine

Mobile Health IoT

Medical Artificial Intelligence

Internet 2000

Smartphone 2007

IBM Watson 2014

GAFAM BATX

ANJH Paris 20 mai 2019

7

Big Data

New medical organizations DocHome

ANJH Paris 20 mai 2019

8

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 4: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

The number of persons aged over 65 years in 2050

the global burden of ageingSource US Bureau of the Census (2000)

ANJH Paris 20 mai 2019

4

ANJH Paris 20 mai 2019

5

Kalid N Zaidan AA Zaidan BB Salman OH Hashim M Muzammil HBased Real Time Remote Health Monitoring Systems A Review on Patients Prioritization and

Related Big Data Using Body Sensors information and Communication Technology

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

5

Health Expenditures

Growth

due to chronic diseases

in the USA

Health expenditures growth per capita

in Western Europe

Finland

France

Germany

Italy

Netherlands

Sweden

United Kingdom

EU members

before May 2004

Denmark

OMS 2011

6

ANJH Paris 20 mai 2019

6

The tools of e-Health to the 21st century

Telemedicine

Mobile Health IoT

Medical Artificial Intelligence

Internet 2000

Smartphone 2007

IBM Watson 2014

GAFAM BATX

ANJH Paris 20 mai 2019

7

Big Data

New medical organizations DocHome

ANJH Paris 20 mai 2019

8

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 5: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

ANJH Paris 20 mai 2019

5

Kalid N Zaidan AA Zaidan BB Salman OH Hashim M Muzammil HBased Real Time Remote Health Monitoring Systems A Review on Patients Prioritization and

Related Big Data Using Body Sensors information and Communication Technology

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

5

Health Expenditures

Growth

due to chronic diseases

in the USA

Health expenditures growth per capita

in Western Europe

Finland

France

Germany

Italy

Netherlands

Sweden

United Kingdom

EU members

before May 2004

Denmark

OMS 2011

6

ANJH Paris 20 mai 2019

6

The tools of e-Health to the 21st century

Telemedicine

Mobile Health IoT

Medical Artificial Intelligence

Internet 2000

Smartphone 2007

IBM Watson 2014

GAFAM BATX

ANJH Paris 20 mai 2019

7

Big Data

New medical organizations DocHome

ANJH Paris 20 mai 2019

8

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 6: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Health expenditures growth per capita

in Western Europe

Finland

France

Germany

Italy

Netherlands

Sweden

United Kingdom

EU members

before May 2004

Denmark

OMS 2011

6

ANJH Paris 20 mai 2019

6

The tools of e-Health to the 21st century

Telemedicine

Mobile Health IoT

Medical Artificial Intelligence

Internet 2000

Smartphone 2007

IBM Watson 2014

GAFAM BATX

ANJH Paris 20 mai 2019

7

Big Data

New medical organizations DocHome

ANJH Paris 20 mai 2019

8

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 7: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

The tools of e-Health to the 21st century

Telemedicine

Mobile Health IoT

Medical Artificial Intelligence

Internet 2000

Smartphone 2007

IBM Watson 2014

GAFAM BATX

ANJH Paris 20 mai 2019

7

Big Data

New medical organizations DocHome

ANJH Paris 20 mai 2019

8

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 8: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

New medical organizations DocHome

ANJH Paris 20 mai 2019

8

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 9: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

The Health-HUB system before 2007

ANJH Paris 20 mai 2019

9

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 10: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Today smartphone for Quantified self

ANJH Paris 20 mai 2019

10

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 11: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Data transmission

Data access

General

Practitioner

Hospital amp EPR

Hospital (Hospital Cliacutenic amp Hospital Mataroacute)Patientrsquos situation (at home)

Patient

Videoconference System amp

Patient Portal

Telemonitorin

g devices

Clinical Patient

Management

System

NurseHospital

video

interface

Interface amp

Gateway

Case Manager

Nurse

Hospital

Specialist

Call Centre amp Health coach

New medical organization cooperation

City-Hospital in Catalonia10

ANJH Paris 20 mai 2019

11

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 12: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

HomeCare in patients with chronic

diseases Overall Scheme

Sensors for multi-parametric monitoring

Hospital

Health call

Centre

Data communication and feedback

Data processing amp analysisData acquisition

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

500

1000

1500

t [sec]

RR

[mse

c]

TiltSympthoms

200 400 600 800 1000 1200 1400 1600 1800 2000 220050

100

150

t [sec]

SBP

[mm

Hg]

200 400 600 800 1000 1200 1400 1600 1800 2000 22000

50

100

SCM

I [

]

t [sec]

200 400 600 800 1000 1200 1400 1600 1800 2000 2200

-05

0

05

Ris

k [-

-]

t [sec]

Positive VVS Risk

Medical

expertise

Intelligent

analysis

Support to diagnosis

decision amp treatment

11

ANJH Paris 20 mai 2019

12

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 13: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

ANJH Paris 20 mai 2019

13

J Med Syst 2017 Dec 2942(2)30 doi 101007s10916-017-0883-4 Review

14

Clinical data collection for an algorithmic medicine

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 14: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Remote monitoring (RM) of renal replacement treatments14

ANJH Paris 20 mai 2019

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 15: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

ldquo

rdquo

Despite growing evidence for the use of RM in

the management of patients with ESRD

(including peritoneal dialysis and home

haemodialysis) this disease had the lowest

recognition of RM value in this current research

Katherine Rojahn1 Suzanne Laplante1 James Sloand1 Claire Main2 AftabIbrahim2 Janet Wild2 Nicky Sturt2 Thelga Areteou3 and K Ian Johnson3

Remote Monitoring of Chronic Diseases A Landscape Assessment of Policies in Four European Countries (United Kingdom Geremany Italy Spain)

PLoS One 2016 May 1911(5)e0155738 doi 101371journalpone0155738 eCollection 2016

ANJH Paris 20 mai 2019

15

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 16: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

ldquo

rdquo

The evidence regarding the quality of care

delivered by telemedicine and telenephrology

in particular compared with in-person care is

limited in USAhellip

Videoconferencing is widely used in Australia to manage kidney disease including chronic

kidney disease dialysis pediatric nephrology

and post-kidney transplantation carehellip

Rohatgi R Ross MJ Majoni SW Telenephrology current perspectives and

future directions Kidney Int 2017 Dec92(6)1328-1333 doi

101016jkint201706032 Epub 2017 Oct 12 Review

ANJH Paris 20 mai 2019

16

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 17: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Remote monitoring of renal

replacement treatments in France and

in EuropePatients treated by Dialysis

ANJH Paris 20 mai 2019

17

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 18: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Teledialysis in Tromsouml since 2001

TMS

Tromsoslash

Vefsn

Sandnessjoslashen

Rana

Harstad

Hammerfest

Narvik

Lofoten

Bodoslash

Kirkenes

Alta

bull Control

bull Remote visit guidance and teachingANJH Paris 20 mai 2019

18

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 19: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Mapes DL Lopes AA

Satayathum S McCullough

KP Goodkin DA Locatelli F

Fukuhara S Young EW

Kurokawa K Saito A Bommer

J Wolfe RA Held PJ Port FK

Health-related quality of life

as a predictor of mortality and

hospitalization the Dialysis

Outcomes and Practice

Patterns Study (DOPPS)

Kidney Int 2003 Jul64(1)339-

49

ANJH Paris 20 mai 2019

19

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 20: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Teledialysis in BrittanySt Brieuc-Lannion (since June of 2001)

ANJH Paris 20 mai 2019

20

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 21: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Remote monitoring in teledialysis

Software that processes the parameters

of the session in real time

ANJH Paris 20 mai 2019

21

Software that processes the settings

for each session for a period of 6 mois

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 22: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Predictive diagnosis of vascular access stenosis

ANJH Paris 20 mai 2019

22

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 23: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Teleconsultation at the end of hemodialysis session

ANJH Paris 20 mai 2019

23

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 24: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Validation of teledialysis process by

French Health Authority in january 2010

Janvier 2010

ANJH Paris 20 mai 2019

24

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 25: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Introduction of teledialysis in a new decree

in February 2012

Home

dialysis

Satellite

dialysis

Satellite dialysis

with nurse

Heavy dialysis

center

Doctor time given by the end of session teleconsult

On-site nephrology

team

Cs month Cs et visitmonth Visitweek

Consent of the patient

Patient stabilized in dialysis treatment

Decree of

september 2002Telemedicine decreeof february 2012

ANJH Paris 20 mai 2019

25

Lighted dialysis

center (UDM)

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 26: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Compliance of the dialysis population to quality indicators

Pre dialytic phosphate (mmoll)

Summary graph of the dialysis population

Patients below the normal range

Patients over the

normal range

ANJH Paris 20 mai 2019

26

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 27: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Diatelic system in Peritoneal Dialysis

since 2001(1)

ANJH Paris 20 mai 2019

27

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 28: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Diatelic system in Peritoneal Dialysis

since 2001(2)

Patient nurse family physician give dialysis data from home over

the internet

By secure messaging the patient expresses his ou her remarks with

the healthcare team by continuous exchange

=gt

ANJH Paris 20 mai 2019

28

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 29: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

ldquo

rdquo

In the nephrology setting home telemonitoring has

been evaluated in home dialysis patients but data

are scarce concerning chronic kidney disease (CKD)

patients before and after renal replacement

therapy The eNephro study is designed to assess thecost effectiveness clinicalbiological impact and

patient perception of a home telemonitoring for

CKD patients

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R

Laplaud D Noeumll C Kessler M Cost-effectiveness of home telemonitoring in chronic

kidney disease patients at different stages by a pragmatic randomized controlled

trial (eNephro) rationale and study design BMC Nephrol 2017 Apr 518(1)126

doi 101186s12882-017-0529-2

ANJH Paris 20 mai 2019

29

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 30: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

The future in remote monitoring of patients treated by

hemodialysis ETAPE Program led by French Ministry

of Health and Health Insurance (2018-21)

Experimentation of telemonitoring funding in hemodialysis patients outside the heavy dialysis center

A precise perimeter (autodialysis UDM homehemodialysis ()) strict eligibilityconditions Patients should be extracted from heavy dialysis center

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient Study followed by HealthInsurance information system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the healthprofessional responsible for the therapeutic accompaniment the provider of theremote monitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

30

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 31: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

31 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 32: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Remote monitoring of renal

replacement treatmentsPatients treated by kidney graft

ANJH Paris 20 mai 2019

32

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 33: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

The future in remote monitoring of patients treated by

kidney graft ETAPE Program led by French Ministry of

Health and Health Insurance (2018-21)

Experimentation remote monitoring funding of patients grafted for more than 6months

A precise perimeter strict eligibility conditions

A minimum number of monitoring parameters for each session

Targets for reduction of expenditures per patient followed by Health Insuranceinformation system (SNIIRAM)

Remuneration of three actors the prescriber nephrologist the health professionalresponsible for the therapeutic accompaniment the provider of the remotemonitoring service

If the target is exceeded 50 of th profits are donated to the three actors

Prescription may be renewed after six months

Results in september 2021

ANJH Paris 20 mai 2019

33

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 34: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

34 ANJH Paris 20 mai 2019

Remuneration and interest of the actors

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 35: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Three prospectives studies controlled and

randomized (results end 2019-2020)

Foucher Y Meurette A Daguin P Bonnaud-Antignac A Hardouin JB Chailan S Neau K Papuchon E Gaboriau S Legendre C Moreacutelon E Tessier P Giral M

A personalized follow-up of kidney transplant recipients using video conferencing basedon a 1-year scoring system predictive of long term graft failure (TELEGRAFT study) protocolfor a randomized controlled trial

BMC Nephrol 2015 Jan 28 16 6 doi 1011861471-2369-16-6

Thilly N Chanliau J Frimat L Combe C Merville P Chauveau P Bataille P Azar R Laplaud D Noeumll C Kessler M

Cost-effectiveness of home telemonitoring in chronic kidney disease patients at differentstages by a pragmatic randomized controlled trial (eNephro) rationale and study design

BMC Nephrol 2017 Apr 518(1)126 doi 101186s12882-017-0529-2

Pape L de Zwaan M Tegtbur U Feldhaus F Wolff JK Schiffer L Lerch C Hellrung N KliemV Lonnemann G Nolting HD Schiffer M

The KTx360deg-study a multicenter multisectoral multimodal telemedicine-based follow-upcare model to improve care and reduce health-care costs after kidney transplantation inchildren and adults

BMC Health Serv Res 2017 Aug 23 17(1)587 doi 101186s12913-017-2545-0

ANJH Paris 20 mai 2019

35

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 36: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

Conclusions

In the 21st century home telemonitoring has developed

considerably over recent years in most chronic diseases in order

to improve communication between healthcare professionals

and patients and to promote early detection of deteriorating

health status

Nephrologists have been precursors to home care some forty

years ago they have to develop them again with the use of

digital tools

Medical Artificial Intelligence will help healthcare professionals

deliver quality home care to patients with chronic kidney

disease

ANJH Paris 20 mai 2019

36

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention

Page 37: Remote monitoring of renal replacement treatments · delivered by telemedicine, and telenephrology in particular, compared with in-person care is limited in USA….. Videoconferencing

37 ANJH Paris 20 mai 2019

Thankrsquos

for your

attention