RelyX Ultimate · Dr. Rainer Guggenberger Corporate Scientist. Product features of RelyX™...

A Collection of Scientific Results

Adhesive Resin Cement

RelyX™ Ultimate

Adhesive dentistry is all about reliability, esthetics and simplification of procedures, RelyX™ Ultimate Cement offers it all.

When performing adhesive dentistry, it is important to know and understand the level of performance of the material at hand. RelyX™ Ultimate Adhesive Resin Cement is attracting a high level of interest amongst the global research community for dental materials. This brochure provides an overview of the most relevant studies. These studies have been compiled by subject matter, first of all separating them by the in vivo or in vitro nature of the study. Secondly, sorting according to the type of study: ranging from bond strength testing on most substrates as well as wear resistance, marginal seal and tests relating to esthetic performance.

As the inventors of multiple dental cement classes, 3M ESPE has worked with renowned universities and research institutes worldwide to provide data you can trust.

Here in our research center we are proud to extend our range of products with RelyX™ Ultimate Cement, to further help you achieving outstanding clinical results and simplifying your daily practice.

With best regards,

Dr. Rainer GuggenbergerCorporate Scientist

Product features of RelyX™ Ultimate Cement 4

1. Product description 62. Indications 83. More information 9

RelyX™ UltimateAdhesive Resin Cement

In vivo evaluations and independent rating 101. Independent rating 122. Handling study 133. Longer-term clinical evaluations 14

Handling guide reference and Clicker™ Dispenser 61

References 64

In vitro testing 18

1. Bond strength to tooth 202. Bond strength to tooth and restoration materials 383. Bond strength to restoration materials 444. Wear resistance 545. Marginal seal 566. Esthetics 58

Product features of RelyX™ Ultimate Cement

Product description

RelyX™ Ultimate Cement is an innovative dual-cure, adhesive resin cement. The cement was developed with the specific needs of glass ceramic cementation in mind, ensuring uncompromising results and ultimate bond strength as well as high, long-lasting esthetics.

Apart from being well suited for glass ceramic cementation indications, RelyX™ Ultimate Cement actually covers the whole spectrum of indirect indications and contains everything a clinician needs to complete any (adhesive) cementation procedure.

The cement was designed for optimal performance when combined with Scotchbond™ Universal Adhesive. RelyX™ Ultimate Cement has an integrated dual-cure activator for Scotchbond™ Universal Adhesive which eliminates the need for a separate activator and the corresponding additional steps. Scotchbond™ Universal Adhesive is a one-component dental adhesive, designed to cover all techniques and indications. It can be used in a self-etch mode, selective enamel-etch mode or in a total-etch (“etch and rinse”) mode for both direct and indirect dental restorative procedures. In addition to serving as the adhesive on tooth substance, Scotchbond™ Universal Adhesive also functions as a metal and zirconia primer as well as a silane.

Benefits at a glance

• Ultimate bond strength

• Fewer components (eliminates the need for up to 4 separate bottles)

• Can be used in either self-etch, selective-etch or total-etch approach

• Dual-cure with integrated dual-cure activator for Scotchbond™ Universal Adhesive

• High esthetics and tooth-like fluorescence

• Moisture tolerance for challenging clinical situations

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Automix delivery*

RelyX™ Ultimate Cement is delivered in an automix syringe containing 8.5 g base paste/catalyst paste, which is sufficient for approximately 16 crown applications.

For color coordination there are four different shades: Translucent, B 0.5 (Bleach), A1 and A3 Opaque. Corresponding try-in pastes are available as well. Shelf life in the aluminum pouch is 18 months. Neither the cement nor the adhesive require refrigeration. Storage at a temperature of 15 – 25 °C/59 – 77 °F is recommended.

* In some countries, RelyX™ Ultimate Cement is available in the Clicker™ Dispenser, see page 61.

Two components are all you need

Compared to the complexity of other leading dental cements:

Multilink® Automix

Panavia™ F2.0

Variolink® II with Syntac

NX3 with OptiBond® Solo Plus™/All-In-One

2RelyX™ Ultimate Adhesive Resin Cement Scotchbond™

Universal Adhesive

4

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Adhe

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Pr

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Adhe

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Pr

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B

Adhe

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Pr

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B

Cera

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Pr

imer

Adhe

sive

Pr

imer

A

Cement Paste A

Cement Paste B

Cement Base

Cement Catalyst Bond

Rest

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Prim

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Adhe

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Sila

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Self-

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Adhe

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Indications

RelyX™ Ultimate Cement covers the whole spectrum of indirect indications:

• Final cementation of all-ceramic, composite or metal inlays, onlays, crowns and bridges; 2 – 3-unit Maryland bridges and 3-unit inlay/onlay bridges*

• Final cementation of all-ceramic or composite veneers

• Final cementation of all-ceramic, composite, or metal restorations to implant abutments

• Final cementation of posts and screws

…and is especially designed for glass ceramics

* Excluded for patients with bruxism or periodontitis.

The kits contain everything a clinician needs to complete any cementation procedure.

RelyX™ Ultimate Trial Kit – A1 (56894)

RelyX™ Ultimate Introductory Kit (56891)

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3M ESPE Cement Selection Guide (2013)3M ESPE Cement Booklet (2013)

Technical Data Sheet RelyX™ Ultimate Adhesive Resin Cement (2012)

More information

For further information on RelyX™ Ultimate Cement and the whole spectrum of 3M ESPE cements please visit 3MESPE.com or refer to the following:

Product brochure RelyX™ Ultimate Adhesive Resin Cement (2011)

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In vivo evaluations and independent rating

RelyX™ Ultimate Cement was evaluated and rated 4 stars in 2012 by REALITY. Reality Now, November-December 2012, 238

Aim of the study: To assess handling properties of a new shade-matched dual-cure adhesive resin cement suitable for self-etching, and total-etching/etch and rinse procedures (Suglue-10*, 3M ESPE, Seefeld, Germany), and its delivery system.

Protocol: 10 UK general dental practitioner members of the practice-based research group, The PREP Panel, received four different shaded syringes, the novel bonding-agent, dispensing tips and instructions for use for two-months. A questionnaire was designed to evaluate current resin-based cementation usage, and to rate the presentation, instructions, dispensing, and handling of the new material. Most responses were on a visual analogue scales (VAS).

Results: All evaluators (100 %) previously used a resin-based cementation system, 6 (60 %) also used a ‘conventional’ system. The main reasons for choice of cementation materials were ease of use and reliability. With 98 restorations placed, the test material scored similarly for ease of use to the previously used resin-based material (4.2 v 4.4 on a VAS where 1 = difficult to use and 5 = easy to use). The new material was scored ideal for vis-cosity, and also for dispensing and handling (4.9 on a VAS where 1=incon-venient & 5=convenient). 80 % (n=8) of the evaluators stated the available

Innovative colour matched multi-purpose resin based cementation system evaluated by general practitionersPublished in: Journal of Dental Research 2012, 90 (Spec. Issue A), 979 Published by: R.J. Crisp, and F.T. Burke, School of Dentistry, University of Birmingham, Birmingham, United Kingdom

RelyX™ Ultimate was awarded the top 5+ rating and selected as editor’s choice. The Dental Advisor/Editor´s choice, June 2012, Vol. 29, No. 5

Independent rating


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RelyX™ Ultimate Cement – Clinical use including post-operative sensitivityAvailable from: 3M ESPE field evaluation (internal data)

Aim of the study: More than 3,700 restorations were placed with RelyX™ Ultimate Cement in an in-office evaluation with over 130 dentists from Europe and more than 90 from the U.S. 90 % of the testers were satisfied or even very satisfied with the product. Ease of use, strong adhesion and paste viscosity were named as the dentists’ most preferred features. The post-operative sensitivity rate was very low. All together 20 cases of post-operative sensitivities out of 5,310 cases were reported by 13 dentists.

3M ESPE Summary: This global application test showed that RelyX™ Ultimate Cement and Scotchbond™ Universal Adhesive are very easy and safe to use. There is very low post-operative sensitivity.

shades were sufficient and 60 % (n=6) used the try-in pastes. 90 % (n=9) of the evaluators agreed that it was both a clinical advantage a) to use the same luting material for all indications, including cementation of zirconia restorations, and b) for the ability of the bonding agent to bond to tooth and be a silane and restoration primer. 80 % (n=8) of the evaluators would both purchase the new cementation system and recommend it to colleagues.

Conclusions: The new resin-based shade-matched adhesive cementation material and its delivery system performed well in this handling evaluation with high scores handling and ease of use. *Suglue – 10 = RelyX™ Ultimate

Reprinted with permission from the Journal of Dental Research 2012, J Dent Res 90 (Spec Iss A): 979Sponsored in part by 3M ESPE

For further reading: The PREP Panel evaluates 3M ESPE’s RelyX™ Ultimate Adhesive Resin Cement. F.J. Trevor Burke, Russell J. Crisp The Dentist, April 2013, 54 - 58

0.38 %

99.62 % No post-operative sensitivities

Handling study

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One-year evaluation of CAD/CAM nano-ceramic and leucite-reinforced onlaysPublished in: Journal of Dental Research 2014, 93 (Spec. Issue A), 100

Published by: D.J. Fasbinder, G.F. Neiva, J.B. Dennison, D. Heys, and R. Heys, University of Michigan, Ann Arbor, MI, U.S.A.

Aim of the study: This randomized, longitudinal clinical trial evaluated the clinical performance of chairside CAD/CAM onlays made from nano-ceramic (LU = Lava™ Ultimate/3M ESPE) and leucite-reinforced (EC=EmpressCAD/Ivoclar) materials using two adhesive cementation techniques.

Protocol: Two clinicians placed 120 onlays (60 LU and 60 EC) in 86 patients: 82 in molars and 38 in premolars. The preparations were consistent with guidelines for all-ceramic onlays with a minimum of 1.5 mm occlusal reduction. The CEREC AC Bluecam (Sirona) was used for image acquisition, design, and milling of the onlays in a single appointment. The internal surfaces of the LU onlays were air abraded with 30 micron silica (CoJet™, 3M ESPE), coated with Scotchbond™ Universal Adhesive (3M ESPE) and dried. The internal surface of the EC onlays were etched with 4.9 % HFl acid, rinsed, dried and coated with a silane coupler (Monobond Plus/Ivoclar). Thirty onlays of each type were cemented with either self-etching and a dual-cure resin cement (SR = Scotchbond™ Universal Adhesive + RelyX™ Ultimate, 3M ESPE) or total-etching and a dual-cure resin cement (EV = Excite + Variolink II/Ivoclar). Recall evaluations were at baseline, 6 months and 1 year.

Longer-term clinical evaluations


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Results: Seven LU onlays and five EC onlays reported mild cold sensitiv-ity that resolved without treatment by the forth week. The onlays were evaluated by two independent examiners using modified USPHS criteria. Both LU and EC groups had 100 % alpha scores for color match, margin discoloration, surface finish, anatomic form, crown fracture, caries, surface gloss and margin adaptation at baseline, 6 and 12 months. One EC onlay fractured at 10 months and was replaced. One LU onlay required endodontic treatment at 6 months.

Conclusion: Both nano-ceramic and leucite-reinforced onlays cemented with self-etching and a dual-cure resin cement or total-etching and a dual-cure resin cement have performed similarly well at one year. This

study was supported by a grant from 3M ESPE.

Reprinted with permission from the Journal of Dental Research 2014, J Dent Res 93 (Spec Iss A): 100

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RelyX™ Ultimate Adhesive Resin Cement – Two-year clinical performanceExcerpt from: The Dental Advisor, 2014

Aim and results of the study: During a 28-month period, over 1,000 restorations where cemented with RelyX™ Ultimate Cement and Scotchbond™ Universal Adhesive by 4 dentists. The restorations included mostly crowns; bridges (3, 4 and 5 units); and a few inlays, onlays and veneers (Fig. 1). The vast majority were silica-based ceramic and zirconia restorations (Fig. 2).

86%

12%2% Crowns

Bridges (3, 4 and 5 units)

Inlays/onlays, veneers

Fig. 1: Distribution of restorations evaluated at two years (n = 577)

86%

12%2% Crowns

Bridges (3, 4 and 5 units)

Inlays/onlays, veneers

Zirconia-based

Silica-based

PFM71%

28%1%

Fig. 2: Distribution of restorations materials

Zirconia-based

Silica-based

PFM71%

28%1%


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Results at two-year recall: 577 restorations (Fig. 1) were recalled. The recalled restorations were evaluated for lack of sensitivity, resistance to marginal staining and retention. Each category was rated on a scale of 1 to 5, where 1 = poor, 2 = fair, 3 = good, 4 = very good and 5 = excellent. All categories where rated excellent (Fig. 3).

Consultants’ comments:

“Loved the simplicity of the system.”

“Very retentive cement with extremely high retention rate.”

Conclusion: RelyX™ Ultimate Adhesive Resin Cement used with Scotchbond™ Universal Adhesive performed exceptionally well at the two-year recall, based on observations of low sensitivity, minimal margin-al discoloration and high retention rate. RelyX™ Ultimate Cement received a 99 % clinical performance rating.

For further reading: RelyX™ Ultimate Adhesive Resin Cement. One-year clinical performance. (The Dental Advisor, 2013)

Lack of sensitivity

RetentionResistance to marginal staining

Fig. 3: Results at two-year recall

5

4

3

2

1

Ratin

g

4.9 4.9 4.9

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In vitro testing

RelyX™ Ultimate Cement shows higher bond strength to dentin than Multilink® Automix

Bond strength of RelyX™ Ultimate Cement/ Scotchbond™ Universal Adhesive Published in: Journal of Dental Research 2013, 92 (Spec. Issue A), 1053

Published by: P. Nelson, R.A. Yapp, and J.M. Powers, Dental Consultants, Inc, Ann Arbor, MI, U.S.A.

Aim of the study: To compare the shear bond strength of RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive (3M ESPE) cement system to Multilink® Automix/Monobond Plus/Multilink® Primer A&B (Ivoclar Vivadent) on human ground enamel, superficial dentin, zirconia (Z) (Glidewell Laboratories) and lithium disilicate (LD) (Ivoclar Vivadent).

Protocol: All substrates were embedded in acrylic discs and ground using 600-grit SiC paper. The bonding agent was applied to the tooth substrates according to the manufacturer’s instructions without light curing. LD specimens were etched with hydrofluoric acid. Z specimens were sandblasted with 50 µm alumina prior to applying the primer. A 0.13 mm thick adhesive PTFE tape with a 3.0 mm diameter hole was positioned over the bonding agent/primer. A dab of the cement was applied in the hole in the tape followed by placement of a pre-molded, light-cured and silane coated TPH3 composite disc (8 mm diameter, 2 mm thick). A 60 g load was placed on the assembly for two minutes and cured for 40 seconds. Specimens were stored in 37 °C /98.6 °F water for 24 hours prior to testing. Bond strength was determined on a universal testing machine at a crosshead speed of 1 mm/minute. Data were analyzed by analysis of variance and means were compared by

Fisher’s PLSD intervals calculated at the 0.05 level of significance.

Results:Ultradont Shear Bond Strength, MPa (SD)*

Cement System Enamel Dentin LD Z

RelyX™ Ultimate Cement/ Scotchbond™ Universal Adhesive

33.3ac (4.5) 39.5d (4.9) 31.5bc (5.3) 38.9d (8.6)

Multilink® Automix/Monobond Plus/Multilink® Primer A&B

35.4ac (4.1) 33.4a (3.8) 30.3d (6.2) 20.2 (1.8)

* Means with matching superscripts are statistically equivalent.

1. Bond strength to tooth

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Conclusion: Statistically, the shear bond strengths of the RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive cement system exceeded those of the Multilink® Automix cement system when bonding to dentin and Z. The shear bond strengths of the two cement systems to enamel and LD were statistically equivalent. This abstract is based on research that was funded entirely or partially by an outside source: 3M ESPE

3M ESPE Comments: The bond strength of RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive is equal to or better than Multilink® Automix/Monobond Plus/Multilink® Primer A&B on tooth and restoration

materials.

Results found in abstracts for Scotchbond™ Universal Adhesive also apply to products registered under the following names: Single Bond Universal Adhesive.


In vitro testing

1.

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Shear bond strength of self-adhesive resin cement* above/below CEJ Published in: Journal of Dental Research 2013, 92 (Spec. Issue A), 1059

Published by: S. Saboree, A. Perera, M. Harsono, M. Finkelman, and G. Kugel, School of Dental Medicine, Tufts University, Boston, MA, U.S.A.

Aim of the study: To test the shear bond strength of three different self-adhesive cements incorporating selective etching technique above and below the CEJ (on enamel and cementum).

Protocol: Twenty-eight caries-free human extracted teeth were sectioned at the CEJ and longitudinally to provide two enamel and two cementum surfaces. The samples were randomly divided into 12 groups (n = 8, six groups above CEJ (enamel), 6 groups below CEJ (cementum)). Each sample was embedded in acrylic to facilitate mounting, flattened and polished with Sic paper up to 320-grit (Ecomet 3, Buehler). Three cements were tested with variations in selective-etch technique: SpeedCEM® (Ivoclar Vivadent), Multilink® (Ivoclar Vivadent) and RelyX™ Ultimate Cement (3M ESPE). Cements were applied according to manufacturer’s suggestion with the exception of using the total-etch technique or pre-treating with etch (37 % H2PO4). Lithium disilicate buttons, approximately 3 mm in diameter, were cemented and cured for 40 seconds with LED light (DEMI, Kerr). After storage in water for 24 hours, the shear bond strength was carried out using a universal testing machine (Instron 5566A, Norwood, MA) with a crosshead speed at 1 mm/minute. Statistical analysis was done by one-way ANOVA, with post-hoc analysis conducted via Tukey HSD with Bonferroni correction.

RelyX™ Ultimate Cement shows high bond strength above and below the cement enamel junction


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Results:

Conclusion: For applications above the CEJ, etching prior to cementation yielded significantly higher shear bond strength for SpeedCEM® and RelyX™ Ultimate Cement groups. Below the CEJ there is no conclusive benefit to etching prior to application of the cement.

3M ESPE Comments: For RelyX™ Ultimate Cement and the self-adhesive resin cement etching the enamel above the CEJ before cementing yielded significantly higher bond strength results than cementing on unetched enamel. Etching the cementum did not show a clear benefit. Overall RelyX™ Ultimate Cement showed the highest measured bond strength values.

* Multilink® Automix and RelyX™ Ultimate Cement are adhesive resin cements.Reprinted with permission from the Journal of Dental Research 2013, J Dent Res 92 (Spec Iss A): 1059

CEJ (MPa ± SD)

Above Below

SpeedCEM® Etched 17.56 ± 5.841,2 5.53 ± 3.37b

Unetched 8.09 ± 3.14A 11.72 ± 6.09x

Multilink® Etched 11.35 ± 5.772 10.24 ± 3.75b, c

Unetched 14.19 ± 8.59A 13.68 ± 9.55X

RelyX™ Ultimate Cement

Etched 26.98 ± 6.551 17.11 ± 6.32c

Unetched 18.53 ± 10.32A 17.64 ± 3.75X

Results with varying superscripts are statistically different (P-value < 0.0125).

In vitro testing

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Bond strength of adhesive resin cements to enamel and dentin Published in: Journal of Dental Research 2013, 92 (Spec. Issue A), 1058

Published by: A. Piwowarczyk, S. Ernst, W.H. Arnold, and E.A. Naumova, University of Witten/Herdecke, Witten, Germany

Aim of the study: The purpose of this in vitro study was to compare bond strength of different adhesive resin cements and their dedicated adhesives to human enamel and dentin.

Protocol: Following materials/adhesives were tested: Variolink® II/Syntac® Classic/Heliobond (Ivoclar Vivadent) (VAR); Multilink® Automix/Multilink® Primer A+B (Ivoclar Vivadent) (MLA); Panavia™ F2.0/ED Primer II (Kuraray) (PAN); RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive (3M ESPE) (RUA); RelyX™ Ultimate Clicker™ Adhesive Resin Cement/Scotchbond™ Universal Adhesive (3M ESPE) (RUC). Human teeth were embedded in epoxy resin, grounded flat to expose enamel or dentin and polished (grit 600 sandpaper). Dedicated adhesive systems were applied according to the manufacturer’s instructions. Stainless steel cylinders with 2.3 mm diameter were silicated (Rocatec™ Plus), coated with silane (Sil, 3M ESPE) and cemented under pressure (20 g/mm2) onto the teeth and light-cured. Specimens were stored for 22 hours ± 2 hours at 36 °C/97 °F and 100 % relative humidity. Bond strength was measured using a universal testing machine (feed rate: 8 mm/minute). Data obtained were analyzed by using one-way ANOVA.

RelyX™ Ultimate Cement shows high bond strength to enamel and dentin


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In vitro testing

Results:

Conclusion: RelyX™ Ultimate Clicker™ Cement (RUC) reached the highest bond strength values independent of the tested surface. This abstract is based on research that was funded entirely or partially by an outside source: Sponsored in part by 3M ESPE.

3M ESPE Comments: RelyX™ Ultimate Clicker™ Cement/Scotchbond™ Universal Adhesive reached the highest bond strength values to human enamel and dentin. There is no statistical difference between RelyX™ Ultimate Clicker™ Cement and RelyX™ Ultimate Cement.

Results found in abstracts for Scotchbond™ Universal Adhesive also apply to products registered under the following names: Single Bond Universal Adhesive.


Significant differences (p < 0.05) were obtained between the tested adhesive resin cements depending on tooth surface. Materials with the same letter are not significantly different from each other.

Enamel Dentin

Materials Mean [MPa] SD [MPa] Mean [MPa] SD [MPa]

VAR 30.6a,b 9.1 16.8b 5.5

MLA 22.9b 8.9 21.3a,b 7.0

PAN 26.7a,b 8.5 16.3b 6.4

RUA 25.7a,b 12.6 20.4a,b 6.3

RUC 32.4a 5.5 23.5a 5.7

40

30

20

10

0RUA VAR MLA PANRUC

Bond

str

engh

t (M

Pa)

Enamel Dentin

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Shear bond strength of adhesive resin cements to enamel and dentinPublished in: Journal of Dental Research 2011, 90 (Spec. Issue B), 430

Published by: C. Wiedig, R. Hecht, G. Raia, M. Ludsteck and R. Guggenberger, 3M ESPE, Seefeld, Germany

Aim of the study: The purpose of this in vitro investigation was to compare shear bond strength (SBS) of different adhesive resin cements and their dedicated adhesives to bovine enamel and dentin.

Protocol: Materials tested were Multilink® Automix/Multilink® Primer A/B (Ivoclar Vivadent), Panavia™ F2.0/ED Primer II (Kuraray), NX3/Opti-Bond™ Solo Plus (Kerr), Clearfil™ Esthetic Cement/DC Bond (Kuraray), Experimental Cement/Experimental Adhesive* (3M ESPE). Bovine teeth were ground flat to expose enamel or dentin, polished (grit 320 sandpaper), water-rinsed and gently air-dried. Dedicated adhesive systems were applied according to the manufacturers’ instructions. Stainless steel rods were cemented under pressure (20 g/mm2) onto the teeth and light-cured (lc). Specimens were stored for 24 hours at 36 °C/97 °F and 100 % relative humidity. Half of the specimens were artificially aged (5,000 thermo cycles (TC), 5 °C /41 °F – 55 °C/131 °F, 30 seconds dwell time). SBS was measured using a universal testing machine (Zwick Z010, crosshead speed: 0.75 mm/minute). Data ob-tained were analyzed using Multiple Range Test (Fisher’s LSD; p < 0.05; n = 6).

Results: Statistical analysis revealed significant differences between the tested adhesive resin cements depending on tooth surface and storage/aging conditions (see table). Values in one column with different superscript characters are statistically different.

Conclusion: The experimental resin cement and its dedicated adhesive system* show best overall adhesion performance to enamel and dentin under all testing conditions.

RelyX™ Ultimate Cement shows high bond strength to enamel and dentin


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In vitro testing

SBS Dentin Ic 24h [MPa]

SBS Dentin Ic TC [MPa]

SBS Enamel Ic 24h [MPa]

SBS Enamel Ic TC [MPa]

Multilink® Automix/ Multilink® Primer A&B

13.9 ± 2.7b 7.6 ± 4.6a 29.1 ± 5.5b 25.4 ± 9.7a

Panavia™ F2.0/ ED Primer II

26.8 ± 7.5c 26.5 ± 2.7b 40.2 ± 10.1c 39.6 ± 10.6b

NX3/OptiBond™ Solo Plus

8.2 ± 1.9a,b 9.3 ± 2.5a 15.5 ± 4.8a 17.8 ± 5.4a

Clearfil™ Esthetic Cement/ DC Bond

6.5 ± 3.8? 9.7 ± 4.4a 44.3 ± 8.0cd 50.8 ± 9.4c

Exp. Cement/ Exp. Adhesive*

27.5 ± 9.7c 54.2 ± 8.3c 51.2 ± 8.8de 54.5 ± 7.0c

Exp. Cement/ Exp. Adhesive/Etch*

52.4 ± 3.9d 65.3 ± 10.2d 54.8 ± 7.9e 67.3 ± 8.4d

3M ESPE Comments: RelyX™ Ultimate Adhesive Resin Cement and its simplified adhesive system showed best overall adhesion performance in this test, both after 24 hours and after artificial aging, whether used in self-etch or in etch and rinse mode. An additional etching step can increase bond strength to tooth structure with RelyX™ Ultimate Cement.

Reprinted with permission from the Journal of Dental Research 2011, J Dent Res 90 (Spec Iss B): 430

Exp. Cement/Exp. Adhesive/

Etch*

Exp. Cement/Exp. Adhesive*

Multilink® Automix/Multilink®

Primer A&B

Panavia™ F2.0/ED Primer II

NX3/OptiBond™

Solo Plus

Clearfil™ Esthetic Cement/

DC Bond

70

60

50

40

30

20

10

0

Bond

str

engt

h [M

Pa]





Exp. Cement/Exp. Adhesive/

Etch*

Exp. Cement/Exp. Adhesive*

Multilink® Automix/Multilink®

Primer A&B

Panavia™ F2.0/ED Primer II

NX3/OptiBond™

Solo Plus


DC Bond

70

60

50

40

30

20

10

0

Bond

str

engt

h [M

Pa]





* RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive (3M ESPE) = Experimental Cement/Experimental Adhesive

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Shear bond strength of resin cements to dentin and enamel Published in: Journal of Dental Research 2013, 92 (Spec. Issue A), 3042

Published by: J. Bair, S. Bhatt, R.D. Perry, and G. Kugel, School of Dental Medicine, Tufts University, Boston, MA, U.S.A

Aim of the study: To compare different adhesive resin cements regarding the degree of bond strength to dentin and enamel.

Protocol: All materials were tested according to manufacturer’s instructions: Multilink® Automix (MLA, Ivoclar Vivdadent), Panavia™ F2.0 (PANF, Kuraray), Calibra Handmix (CAL, Dentsply), RelyX™ Ultimate Adhesive Resin Cement (RUA, 3M ESPE) and RelyX™ Ultimate Clicker™ Adhesive Resin Cement (RUC, 3M ESPE). RUA and RUC are available in self-etch (SE) and total-etch modes (TE). 140 stainless steel cylinders with 4 mm diameter were sandblasted, silicated (Rocatec™ Plus, 3M ESPE) from 10 mm distance for 15 seconds and coated with silane (Sil, 3M ESPE). 140 bovine teeth were embedded in epoxy resin (SpeciFix) and the dentin and enamel surfaces were cut (diamond) and polished (320 grit sandpaper, wet). The metal cylinders were then cemented to each prepared surface (n = 10) under pressure (20 g/mm2) according to manufacturer’s instructions. Cements were light-cured (Elipar™ S10 LED Curing Light, 3M ESPE) according to instructions and specimens were stored 24 hours at 36 °C /97 °F and 100 % relative humidity. Shear bond strength (SBS) was tested with a universal testing machine (ZwickZ010, crosshead speed: 0.75 mm/minute) and results were analyzed. Statistical analysis was performed by Minitab (Fisher LSD Multiple Range Test, 95 % confidence level, p-value < 0.05). Values with the same characters are statistically not different.

RelyX™ Ultimate Cement shows high bond strength in the self-etch mode


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In vitro testing

Results:

Conclusion: RUA and RUC showed highest bond strength in total-etch mode for both dentin and enamel. In the self-etch mode RUA and RUC were at least equivalent to the total-etch systems tested. CAL showed relatively low bond strength to dentin. Higher bond strength may indi-cate higher clinical performance.

3M ESPE Comments: RelyX™ Ultimate Adhesive Resin Cement in the automix syringe as well as the Clicker™ Dispenser showed highest bond strength in total-etch mode for both dentin and enamel. In the self-etch mode RelyX™ Ultimate Adhesive Resin Cement achieved results which were at least equivalent to other total-etch systems tested with the advantage of less treatment steps.


SBS [MPa ± Std Dev]

Cements Dentin Enamel

MLA 24.8 ± 9.8b 42.5 ± 6.4c

PANF 22.7 ± 5.0bc 41.5 ± 7.1c

CAL 17.3 ± 9.7c 48.5 ± 6.0b

RUA-SE 28.8 ± 7.6b 45.1 ± 5.4b,c

RUA-TE 40.8 ± 4.1a 61.1 ± 4.6a

RUC-SE 25.2 ± 7.1b 43.6 ± 4.3bc

RUC-TE 38.1 ± 5.4a 65.0 ± 5.8a

1.

29


Shear bond strength of RelyX™ Ultimate Cement 5 minutes after curingAvailable from: 3M ESPE internal data

Aim of the study: To determine bond strength 5 minutes after light-cure of the cement.

Protocol: Bovine teeth were ground flat to expose dentin, polished (grit 320 sandpaper), water-rinsed. Dedicated adhesive systems were applied according to the manufacturers’ instructions. In all cases the adhesive was not light-cured before applying the cement. Stainless steel rods were cemented under pressure (20 g/mm²) onto the teeth exactly 1 minute after start of mixing the cement. Excess was removed using a probe. The remaining cement was covered with glycerin gel (AIRBLOCK™, Dentsply) and light-cured according to the manufacturers’ instructions. The prepared specimens were stored for 5 min at 36 °C /97 °F. Subsequently the loading weight and glycerin gel were removed and shear bond strength (SBS) was measured (n = 6) using a universal testing machine (Zwick Z010, crosshead speed: 0.75 mm/min). Means and standard deviations were calculated.

Results:

60

40

20

0Multilink® Automix(Ivoclar Vivadent)

RelyX™ Ultimate Cement (etched) (3M ESPE)

RelyX™ Ultimate Cement(3M ESPE)

MPa

Shear bond strength of RelyX™ Ultimate Cement 5 minutes after curing

Enamel Dentin

RelyX™ Ultimate Cement was used with Scotchbond™ Universal Adhesive (no separate light-cure) (both 3M ESPE), Multilink® Automix with Multilink® Primer A&B (Ivoclar Vivadent) according to manufacturers’ instructions. All cements are light-cured. Source: 3M ESPE internal data. Data available on request.

RelyX™ Ultimate Cement shows reliable initial bond strength


30

In vitro testing

Conclusion: Reliable initial bond strength is achieved with RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive 5 minutes after light-curing. A separate etching step increases the bond strength.

3M ESPE Comments: RelyX™ Ultimate Adhesive Resin Cement shows very high high bond strength 5 minutes after light-cure. The bond strength exceeds that of Multilink® Automix.

1.

31


RelyX™ Ultimate Cement was used with Scotchbond™ Universal Adhesive (no separate light-cure), cement was light-cured. Bond strength was determined after 24h. Source: 3M ESPE internal data. Data available on request.

RelyX™ Ultimate Cement – Adhesion to moist and dry dentinAvailable from: 3M ESPE internal data

Aim of the study: To determine bond strength of RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive to dentin with different degrees of wetting.

Protocol: Bovine teeth were ground flat to expose dentin, polished (grit 320 sandpaper), water-rinsed. Dentin samples were left in different states of wetting from dry to highly moist. Scotchbond™ Universal Adhesive was applied according to the manufacturer’s instructions. In all cases the adhesive was not light-cured before applying the cement. Stainless steel rods were cemented under pressure (20 g/mm²) onto the teeth exactly 1 min after start of mixing the cement. Excess was removed using a probe. The remaining cement was covered with glycerin gel (AIRBLOCK™, Dentsply) and light-cured according to the manufacturer’s instructions. Subsequently loading weight and glycerin gel were removed. The prepared specimens were stored for 24 h at 36 °C/97 °C. Shear bond strength was measured (n = 6) using a universal testing machine (Zwick Z010, crosshead speed: 0.75 mm/min). Means and standard deviations were calculated.

Results:

Dentin shiny but no water pooling

Dentin according to instructions: just dry, slightly glossy

Dentin dry and mat

RelyX™ Ultimate bond strength on wet and dry dentin

60

40

20

0

MPa

RelyX™ Ultimate Cement shows high moisture tolerance


32

In vitro testing

Conclusion: Due to the unique moisture tolerance of RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive, bond strength to dentin is comparable whether the dentin is dry or slightly moist.

3M ESPE comments: Scotchbond™ Universal and RelyX™ Ultimate Cement are moisture-tolerant to a certain degree, which allows the clinician to leave the prepared tooth slightly moist without an impact on bond strength. The main advantage is on the patient side: Low post-operative sensitivities are reported.

1.

33


RelyX™ Ultimate has excellent long-term bond strength to enamel and dentin

Long-term bond strength of resin cements to enamel and dentinPublished in: Journal of Dental Research 2014, 93 (Spec. Issue C), 401

Published by: A. Piwowarczyk, S. Ernst, W. H. Arnold, E. A. Naumova, Witten/Herdecke University, School of Dentistry, Faculty of Health, Witten, Germany

Aim of the study: This in vitro study determined the long-term bond strength of different adhesive resin cements and their dedicated adhesives to human enamel and dentin.

Protocol: A total of 100 extracted non-carious and not root-filled were embedded in epoxy resin, grounded flat to expose enamel or dentin (grit 600 sandpaper). Dedicated adhesive systems were applied according to the manufacturers’ instructions. Stainless steel cylinders (2.3 mm diameter) were silicated (Rocatec™ Plus, 3M ESPE), coated with silane (Sil, 3M ESPE) and cemented under pressure (20 g/mm²) onto the teeth and light cured. Following materials/adhesives were tested: Variolink II/ Syntac® Classic/Heliobond (Ivoclar Vivadent) (VAR); Multilink® Automix/Multilink Primer A+B (Ivoclar Vivadent) (MLA); Panavia™ F2.0/ED Primer II (Kuraray) (PAN); RelyX™ Ultimate Automix/Scotchbond™ Universal Adhesive (3M ESPE) (RUA); RelyX™ Ultimate Clicker™/Scotchbond™ Universal Adhesive (3M ESPE) (RUC). Specimens were stored for 150 days at 36 °C/96.8 °F in artificial saliva and subsequently thermocycled 10,000 times (5/55 °C – 41/131 °F). Bond strength was measured using a universal testing machine (feed rate: 8 mm/min). Data obtained were analyzed by using one-way ANOVA.


34

In vitro testing

Results:

Conclusion: RelyX™ Ultimate Clicker™ (RUC) reached the highest bond strength values independent of the tested surface.

3M ESPE Comments: RelyX™ Ultimate Cement in the automix or in the Clicker™ delivery have longterm bond strength values to enamel and dentin which are equivalent to or better than other leading adhesive resin cements.

Reprinted with permission from the Journal of Dental Research 2014, J Dent Res 93 (Spec Iss C): 401 Sponsored in part by 3M ESPE

Enamel Dentin

Materials Mean [MPa] SD [MPa] Mean [MPa] SD [MPa]

VAR 26.7a,b 12.3 12.9b 7.2

MLA 19.4b 11.2 16.5b 5.4

PAN 31.6a 8.4 18.0b 8.6

RUA 29.7a 5.9 19.2b 8.8

RUC 34.0a 11.6 26.9a 8.3

Significant differences (p < 0.05) were obtained between the tested adhesive resin cements depending on tooth surface. Materials with the same letter are not significantly different from each other.

1.

35


Adhesion of adhesive resin cements to dentinPublished in: Journal of Dental Research 2014, 93 (Spec. Issue A), 1129

Published by: S. Hader, R. Hecht, G. Raia, C. Thalacker, and M. Ludsteck, 3M ESPE, Seefeld, Germany

Aim of the study: This study investigated shear bond strength (SBS) of different adhesive resin cements and their dedicated adhesives to bovine dentin in auto-cure mode.

Protocol: Materials tested were Multilink® Automix/Multilink® Primer A+B (Ivoclar Vivadent) [MLA], Panavia™ F2.0/ED Primer II (Kuraray) [PanF], NX3/OptiBond™ XTR (Kerr) [NX3], Bifix QM/Futura Bond DC (Voco) [BQM], RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive (3M ESPE) [RXU].

Bovine teeth were ground flat to expose dentin, polished (grit 320 sandpaper), water-rinsed. Dedicated adhesive systems were applied according to the manufacturers’ instructions. In all cases the adhesive was not light-cured. Stainless steel rods were cemented under pressure (20 g/mm²) onto the teeth exactly 1 min after start of mixing the cement. Excess was removed using a probe. In case of RXU and MLA remaining cement was covered with glycerin gel (AIRBLOCK™, Dentsply) accord-ing to the manufacturers’ instructions. 2 min after start of mixing the cement prepared specimens were stored for 10 min at 36 °C/96.8 °F. Subsequently loading weight and glycerin gel were removed. Speci-mens were stored for 24 h at 36 °C/97 °F and 100 % relative humidity. SBS was measured after 24 h (n = 6) and after artificial aging with 5,000 thermo cycles (TC) between 5 °C/41 °F and 55 °C/131 °F using a universal testing machine (Zwick Z010, crosshead speed: 0.75 mm/min). Data obtained were analyzed using Multiple Range Test (Fisher’s LSD; p < 0.05).

Results: Values within one column marked with the same superscript characters are not statistically different. A statistical difference within a row before and after aging is marked with numbers.

RelyX™ Ultimate Cement shows reliable bond strength to dentin in self-cure mode


36

In vitro testing

Conclusion: RelyX™ Ultimate Adhesive Resin Cement in combination with Scotchbond™ Universal Adhesive in the auto-cure mode shows equivalent or better adhesion performance compared to other adhesive resin cements. An excellent performance in the auto-cure mode is a key feature for successful cementation of metal-based restorations.

3M ESPE Summary: Reliable bond strength performance to tooth is also achieved in the self-cure mode.

Reprinted with the permission of the Journal of Dental Research 2014, J. Dent. Res. 93 ( Spec. Issue A): 1129.

For further reading:

For abstracts on bond strength to tooth also refer to:

* Bond strength of multi-step cements to enamel and zirconia. C. Decoteau1, M. Oglezki1, G. Kugel2, and R.D. Perry1, 1Tufts University, Boston, MA, 2Research Administration, Tufts University, Boston, MA, U.S.A. (Journal of Dental Research 2011, 90 (Spec. Issue A), 375)

* RelyX™ Ultimate Cement – Microtensile bond strength to bur cut dentin and enamel. Y. Suyama, B. Van Meerbeek, Catholic University Leuven, Belgium. (Available from: 3M ESPE, data on file).

* RelyX™ Ultimate Cement – Technical Data Sheet, 3M ESPE 2012

SBS_24h [MPa]

SBS_TC [MPa]

MLA 18.6±9.7A/1 11.0±6.5a,b/1

PanF 18.5±10.7A/1 15.8±7.5a/1

NX3 12.3±5.6A,B/1 6.0±3.1b,c/2

BQM 5.6±2.5B/1 2.5±1.5c/2

RXU 14.4±3.4A/1 10.8±2.4a,b/1

1.

37


RelyX™ Ultimate Cement shows highest adhesion of zirconia crowns on human teeth

Retention of zirconia crowns bonded with adhesive resin cementsPublished in: Journal of Dental Research 2012, 91 (Spec. Issue A), 1010

Published by: Q. Cai, D. Cakir, P. Beck, L. Ramp and J. Burgess, University of Alabama at Birmingham, Birmingham, AL, U.S.A.

Aim of the study: To measure retention of zirconia crowns cemented with an experimental* (3M ESPE) and 2 commercially available (Multilink® Automix/Ivoclar Vivadent, Panavia™ F2.0/Kuraray) cements under different surface preparation conditions (see table).

Protocol: 50 extracted teeth (n = 10) were embedded in brass holders and placed into a lathe to produce a uniform crown preparation (20 degree taper and 3 mm height). An orientation groove was placed on the occlusal surface using a round bur and high-speed handpiece. Preparations were scanned using Lava™ Chairside Oral Scanner C.O.S. (3M ESPE) and the file sent to 3M ESPE Professional Lab where Lava™ Zirconia copings were milled. Each preparation was imaged with a digital microscope (Keyence/VHX-600) at 20× magnification to measure surface areas and calculate strength by dividing the failure load with bonded surface area. Finished crowns were fit to the preparation, margins checked for opening and fit (explorer does not catch). Crowns were randomly assigned to 5 groups (see table) and cemented following manufacturers’ instructions. A 2 kg weight was placed on the crown during cementation. Margins were light-cured (Elipar™ S10 LED Curing Light/3M ESPE/1100 mW/cm2). Specimens were stored (distilled water/37 °C (98.6 °F)/24 hour), thermocycled (5 – 55 °C (41 – 131 °F)/10,000 cycles/15 seconds dwell time) and load cycled using an acetyl stylus (20 N/100,000 cycles/1.2 Hz). A metal rod was placed through the hole on the coping and attached to the upper member of an INSTRON (Model/5565) and loaded in tension (5 mm/minute) until debonding. Data were analyzed with ANOVA and Tukey/Kramer (p = 0.05).

Bond strength to tooth and restoration materials 2.

38

In vitro testing

Results (Mean ± SD)

Conclusion: Multilink® Automix had lower retention compared to all ex-perimental material* groups (p < 0.05). Difference in retention was also found for Panavia™ F2.0 and experimental cement* when applied on sandblasted and primed surface. Supported by a grant from 3M ESPE.

3M ESPE Comments: RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive demonstrated highest pull off bond strength of crowns in an in vitro model compared to Multilink® Automix and Panavia™ F2.0.


Materials/Manufacturer Load (N) Stress (MPa)

Exp. Cement*/Sandblasted/ 50μ-A1203/3M ESPE

599.9 ± 147.8 5.4 ± 1.3

Exp. Cement*/Sandblasted/ 50μ-A1203/Primed/3M ESPE

716.6 ± 110.5 6.5 ± 1.2

Exp. Cement*/Sandblasted/ 50μ-A1203+ 30μ-CoJet/Primed/3M ESPE

635.2 ± 210 5.1 ± 1.6

Multilink® Automix/Sandblasted/50μ-A1203/Ivoclar Vivadent

393.5 ± 158.2 3.4 ± 1.4

Panavia™ F2.0/Sandblasted/50μ-A1203/Kuraray 446.8 ± 134 3.8 ± 1

RelyX™ Ultimate Cement was used with Scotchbond™ Universal Adhesive (no separate light-curing), the other materials with their respective primers. Zirconia was sandblasted (< 50 µm) before priming. All cements light-cured. Artificial aging: 100,000 load cycles (20N), 10,000 thermocycles (5 °C/41 °F – 55 °C/131 °F).

RelyX™ Ultimate Panavia™ F2.0Multilink® Automix

Zirconia crown pull-off strength of resin cements after artificial aging

MPa

8

6

4

2

0

* RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive from 3M ESPE = Experimental Cement/Experimental Adhesive

2.

39


RelyX™ Ultimate bond strength to dentin in self-etch mode is comparable to Variolink® II total-etch system

Adhesion of indirect ceramic and composite* restorations: influence of chewingPublished in: Journal of Dental Research 2012, 91 (Spec Issue. A), 1300

Published by: G. Turco, A. Frassetto, G. Marchesi, I. Spagnolo, C. Navarra, R. di Lenarda, M. Cadenaro, and L. Breschi, Department of Medical Sciences, University of Trieste, Trieste, Italy

Aim of the study: The purpose of this study was to evaluate the influence of simulated chewing forces on bond strength of ceramic and composite disks luted to dentin with a simplified cement (Scotchbond™ Universal Adhesive and RelyX™ Ultimate Cement, both 3M ESPE) or a multi-step cement (Variolink® II, Ivoclar Vivadent).

Protocol: Eighty noncarious human molars were cut with a low speed diamond saw under water cooling and equally and randomly assigned to two main groups: CS (Chewing Simulation) and Controls (Static Conditions). Specimens were then divided in 4 different luting groups (N = 20): Group 1: Ceramic disks (Feldspathic Ceramic, Vita Mark II, Vita) luted with Scotchbond™ Universal and RelyX™ Ultimate; Group 2: Ceramic disks (Feldspathic Ceramic, Vita Mark II) luted with Variolink® II; Group 3: Composite disks (Lava™ Ultimate, 3M ESPE) and Scotchbond™ Universal and RelyX™ Ultimate; Group 4: Composite disks (Lava™ Ultimate, 3M ESPE) and Variolink® II. Specimens were then either submitted to chewing simulation or stored in water and subsequently cut for microtensile bond strength analysis in accordance with the non-trimming technique. Sticks were stressed until failure with a simplified universal testing machine. Data were statistically analyzed by Student’s T Test (p = 0.05).

Results:

Table 1: Means and standard deviations (SD) of microtensile bond strength (MPa) obtained at luted material/dentin interface. Different superscript letters indicate statistical differences between the groups (p < 0.05).

Luted Material Cement Storage

CS Control

Ceramic SU & RU 12.1 (4.4)a 14.3 (4.7)a,b,c

VII 13.5 (4.7)a,b 16.1 (4.3)c,d

Composite SU & RU 12.6 (4.7)a,b 13.2 (5.3)a,b

VII 14.9 (5.3)b,c 17.8 (5.1)d

* Composite = resin nano ceramic restorations


40

In vitro testing

Conclusions: The simplified luting procedure (Scotchbond™ Universal Adhesive and RelyX™ Ultimate Cement exhibited comparable bond strength values for both ceramic and composite irrespective from the aging condi-tions (both CS and Static). Albeit the strength values were slightly higher before chewing simulation, the multi-step cement (Variolink® II) was signifi-cantly affected by chewing. Further studies are needed to clarify the role of occlusal forces on ceramic bond to dentin.

RelyX™ Ultimate Cement/

Scotchbond™ Universal Adhesive (3M ESPE)


Scotchbond™ Universal Adhesive

(3M ESPE)

Variolink® II Excite DSC total-etch

Monobond Plus (Ivoclar Vivadent)

Vita Mark II Lava™ Ultimate resin nanoceramic



Mictrotensile bond strength to dentin before and after aging

MPa

20

10

0

Control water storage

Chewing


Scotchbond™ Universal Adhesive (3M ESPE)


Scotchbond™ Universal Adhesive

(3M ESPE)



Vita Mark II Lava™ Ultimate resin nanoceramic



Mictrotensile bond strength to dentin before and after aging

MPa

20

10

0

Control water storage

Chewing

Compared to the complexity of other leading dental cements:

Variolink® II with Syntac

2RelyX™ Ultimate Adhesive Resin Cement Scotchbond™

Universal Adhesive

Cement Base

Cement Catalyst Bond

Rest

orat

ion

Prim

er

Adhe

sive

Adhe

sive

Pr

imer 6

3M ESPE Summary: RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive uses a simplified bonding protocol and shows comparable bond strength to Variolink® II.


2.

41


RelyX™ Ultimate shows consistently high bond strength of various ceramic materials to dentin

SBS of lithium disilicate and zirconia ceramic luted to dentin Published in: Journal of Dental Research 2013, 92 (Spec. Issue A), 1088

Published by: C.D. Benitez1, A.L. Fernandez1, M. Finkelman1, R. Ritter2, M. Harsono1, and G. Kugel1, 1School of Dental Medicine, Tufts University, Boston, MA, 2Private Practice, Jupiter, FL, U.S.A.

Aim of the study: The aim of this study was to compare the shear bond strengths of lithium disilicate and zirconia ceramic rods luted to dentin using three different cement systems.

Protocol: A total of sixty extracted caries-free human teeth were obtained for this study. Flat dentin surfaces were prepared using 600 grit SiC paper. 30 lithium disilicate and 30 zirconia cylindrical ceramic rods (2.5 mm × 3 mm) were fabricated and wet ground with 600 grit SiC paper. The lithium disilicate ceramic rods were preconditioned with 5 % hydrofluoric acid for five seconds, rinsed and air-dried. All the ceramic rods were silanated with Monobond Plus (Ivoclar Vivadent) for 60 sec-onds. The flat dentin samples were randomly divided into three groups each luted with ten lithium disilicate and ten zirconia rods. Three luting cements were used per manufacturers’ instructions: Group 1 – Multilink® Automix (Ivoclar Vivadent); Group 2 – Panavia™ F2.0 (Kuraray); and Group 3 – RelyX™ Ultimate Cement (3M ESPE). All samples were light-cured for 20 seconds (DEMI, Kerr). The samples were stored in 100 % humid-ity at 25 °C/77 °F for 24 hours. Shear bond strengths were tested using a Universal testing machine (Instron, Norwood, MA) with a crosshead speed of 1 mm/minute. Statistical analysis was conducted using One-way ANOVA with post hoc Tukey-Kramer test. Statistical significance was predetermined at p < 0.05.


42

In vitro testing

Results:

Conclusion: For shear bond strength of zirconia ceramic luted to dentin, Multilink® Automix and RelyX™ Ultimate Cement groups yielded statistically higher values than Panavia™ F2.0 group.

3M ESPE Comments: For the different ceramics tested, RelyX™ Ultimate Cement showed bond strength values that were comparable to or higher than Multlink® Automix and Panavia™ F2.0.


Means SBS (MPa ± SD)

Group Material Lithium Disilicate Zirconia

1 Multilink® Automix 13.38 ± 7.91a 22.82 ± 5.70c

2 Panavia™ F2.0 14.87 ± 7.33a 9.11 ± 4.56b

3 RelyX™ Ultimate Cement 24.93 ± 13.65a 22.78 ± 8.09c

Results with varying superscripts are statistically different (p < 0.05)

2.

43


RelyX™ Ultimate Cement shows excellent tensile bond strength to zirconia after aging

RelyX™ Ultimate Cement – Bonding durability to zirconia compared to other resin cementsAuthors: F. Lehmann, M. Kern, University of Kiel, Germany

Available from: 3M ESPE, excerpt from clinical report

Aim of the study: To test tensile bond strength of RelyX™ Ultimate Cement in comparison to other resin cements after aging in water at 37 °C and thermocycling (5 °/55 °C) for 75,000 thermocycles.

Protocol: 16 samples of flat zirconia (e.max ZirCAD, Ivoclar Vivadent discs (thickness 3.4 mm, diameter 6.4 mm) were sandblasted (15 sec with 50 µm Al2O3 at 2.5 bar) and cleaned in an ultrasonic bath of Iso-propylalkohol 99 % for 3 minutes. Pretreatment of the zirconia was done according to manufacturers’ instructions for 4 different treatment groups: Panavia™ F2.0 (Kuraray), NX3 Nexus® (Kerr), Multilink® Automix (Ivoclar Vivadent) and RelyX™ Ultimate Cement (3M ESPE) and plexiglas tubes filled with Clearfil™ F II composite (Kuraray) were luted to these samples as previously described [Methodology based on Kern, M., Thompson, VP: A simple experimental arrangement for universal testing of the adhesive bond in the axial tensile test. Dtsch Z Zahnärztl 48, 769-772 (1993)]. Excess was removed with foam pellets, Oxyguard gel (Kuraray) applied to prevent the formation of an inhibition layer and light-curing done from 4 sides for 15 sec each with Elipar™ 2500 Halogen Curing Light (3M ESPE).

8 samples of each cement were stored for 3 days and 8 for 150 days in water at 37 °C/98.6 °F. The samples stored for 150 days received addi-tional intermittent thermocycling with a total of 75,000 cycles between 5 °C/41 °F and 55 °C/131 °F. Bond strength was tested in a tensile bond strength test in a vertical direction at a crosshead speed of 2 mm/min. Data were analyzed for statistical significance using a Kruskal-Wallis-Test and a Wilcoxon test adjusted for Bonferroni-Holm to compare the subgroups. Fracture analysis and SEM – imaging of samples was performed. (p ≤ 0,05).

3. Bond strength to restoration materials

44

In vitro testing

Results:

Conclusion: After aging and thermocycling RelyX™ Ultimate Cement showed the highest remaining bond strength that was statistically signifi-cantly higher than NX3 Nexus® and Multilink® Automix with their respective bonding systems.

3M ESPE Summary: RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive shows reliably high tensile bond strength to zirconia, which is comparable to or better than other leading adhesive resin cements after having been aged and thermocycled for 150 days.

RelyX™ Ultimate Cement,Scotchbond™ Universal

Adhesive

Panavia™ F2.0 NX3 Nexus®Multilink® AutomixMonobond Plus

Tensile bond strength of resin cements to zirconia – 150 days

MPa

40

30

20

10

0

RelyX™ Ultimate Cement was used with Scotchbond™ Universal Adhesive as zirconia primer, the other materials with their respective primers if indicated by manufacturer. Cercon Zirconia was sandblasted (50 μm, 2.5 bar) before priming, all cements were light-cured.

3.

45


RelyX™ Ultimate bondstrength after various cleaning protocols for saliva contaminated zirconia

Adhesion to saliva contaminated zirconia cleaned with different methodsPublished in: Journal of Dental Research 2014, 93 (Spec. Issue A), 169

Published by: C. Thalacker1, G. Raia1, R. Hecht1, S. Hader1, and D. Krueger2, 13M Deutschland GmbH, Seefeld, Germany, 23M ESPE, St. Paul, MN, U.S.A.

Aim of the study: Saliva contamination of zirconia restorations before final cementation can lead to lower bond strength. Aim of this study was to assess the effect of the cleaning protocol (water or Ivoclean (ICL, Ivoclar-Vivadent) on shear bond strength (SBS) of RelyX™ Ultimate Cement (RXU, 3M ESPE) using Scotchbond™ Universal Adhesive (SBU, 3M ESPE) as zirconia primer to saliva contaminated zirconia (Lava™ Plus, 3M ESPE).

Protocol: Sandblasted zirconia discs were contaminated with human saliva and divided into the following groups (n = 5): rinsing with water and air drying (water/air), ICL with rinsing according to manufacturer’s instructions (ICL/water/air), ICL without rinsing (ICL/no rinsing), saliva without cleaning (no cleaning), uncontaminated zirconia (control). Stainless steel rods (4 mm diameter) were cemented onto the zirconia specimens under standardized pressure (20 g/mm²) using RXU and SBU according to manufacturer's instructions. Specimens were stored for 24 h at 36 °C /96.8 °F and 100 % relative humidity. Half of the specimens were artificially aged (5,000 thermal cycles (TC), 5 °C – 55 °C (41 °F – 131 °F), 30 sec dwell time). SBS was measured using a universal testing machine (Zwick Z010, crosshead speed: 0.75 mm/min).

Results: The standard deviations (SD) are given in parentheses. All data per experiment were analyzed by ANOVA and multiple comparisons using Fisher’s LSD procedure (p < 0.05). Means with the same letters are statistically the same.

3.

46

Bond strength to restoration materials

In vitro testing

Conclusion: Multiple statistically significant differences were found for 24 h SBS. No significant difference was found for artificially aged samples. For RXU and SBU, ICL treatment did not improve SBS versus water rinsing. For RXU, water rinsing followed by air drying and SBU application can be recommended in case of saliva contamination of zirconia restorations.

3M ESPE Comments: After saliva contamination of zirconia restora-tions the recommended cleaning protocol before bonding the restora-tion with Scotchbond™ Universal Adhesive and RelyX™ Ultimate Cement is water rinsing followed by air drying. No additional cleaning agents are needed.

Reprinted with the permission of the Journal of Dental Research 2014, J. Dent. Res. 93 (Spec. Issue A): 169

Group SBS[MPa]_24h SBS[MPa]_TC

Water/air 51.0(5.1)A,B 50.7(8.5)a

ICL/water/air 46.9(4.1)B,C 45.4(5.9)a

ICL/no rinsing 53.5(8.0)A,B 48.6(12.3)a

No cleaning 43.1(7.4)C 46.2(9.6)a

Control 55.1(6.1)A,B 47.6(5.2)a

3.

47


RelyX™ Ultimate Cement shows a consistently high bonding performance to all tested ceramics

RelyX™ Ultimate Adhesive Resin Cement adhesion to etchable glass ceramics Published in: Journal of Dental Research 2013, 92 (Spec. Issue A), 1090

Published by: S. Hader, R. Hecht, G. Raia, C. Thalacker, and R. Guggenberger, 3M ESPE, Seefeld, Germany

Aim of the study: This study investigated shear bond strength of RelyX™ Ultimate Cement (RXU 3M ESPE) to various types of etchable glass ceramics and Multilink® Automix (MA, Ivoclar Vivadent) to lithium disilicate ceramic (LDC).

Protocol: Materials tested were feldspathic ceramic (FC) Vitablocs® Mark II (VITA), leucite reinforced ceramic (LRC) IPS Empress CAD® (Ivoclar Vivadent), lithium disilicate ceramic (LDC) IPS e.max CAD® (Ivoclar Vivadent). For shear bond strength (SBS) testing glass ceramic blocs (15 × 15 × 3.5 mm) of FC, LRC and LDC were etched with hydrofluoric acid (HF) and a silane was applied following the manufacturer’s instructions. Silanes used were Scotchbond™ Universal Adhesive (SBU) for RXU and Monobond Plus (MP) for MA. Stainless steel rods were cemented under pressure (20 g/mm2) onto ceramic blocs. After light-curing following the manufacturer’s instructions, specimens were stored for 24 hours at 36 °C /96.8 °F and 100 % relative humidity. Half of the specimens were artificially aged (5,000 thermocycles, 5 °C – 55 °C (41 °F – 131 °F), 30 seconds dwell time). SBS was measured using a universal testing machine (Zwick Z010, crosshead speed: 0.75 mm/minute). Data obtained were analyzed using Multiple Range Test (Fisher’s LSD; p < 0.05).

Results: Values in one column marked with the same superscript characters are not statistically different. For FC and LRC only cohesive failures within the ceramic occurred. For LDC failure mode changed from adhesive (1d) to cohesive (TC).


48

In vitro testing

Conclusion: The system RXU/SBU shows constantly high adhesion performance to all types of etchable glass ceramics and is equivalent on LDC to the dedicated system MA/MP. The switch in failure mode on LDC after TC may be an indicator for a decrease of the mechanical strength of the ceramic.

3M ESPE Summary: RelyX™ Ultimate Cement showed a consistently high bonding performance to all tested ceramics. Results were compa-rable to the adhesion performance of the Multilink® cement system to lithium disilicate ceramic.


Material SBS 1d [MPA] SBS TC 5.000x [MPA]

FC/HF/SBU/RXU 44.3 ± 4.6a 45.2 ± 3.4c

LRC/HF/SBU/RXU 46.9 ± 3.0a 47.9 ± 4.0b,c

LDC/HF/SBU/RXU 46.2 ± 2.2a 49.1 ± 4.1b,c

LDC/HF/MP/MA 44.0 ± 7.8a 50.6 ± 5.2b

3.

49


RelyX™ Ultimate Cement with Scotchbond™ Universal Adhesive as a primer achieves highest bond-strength to different restoration materials

Shear bond strength of adhesive resin cements to different restoration materialsPublished in: Journal of Dental Research 2012, 91 (Spec. Issue A), 641

Published by: C.A. Wiedig, R. Hecht, G. Raia, M. Ludsteck, and C. Thalacker, 3M ESPE, Seefeld, Germany

Aim of the study: The purpose of this in vitro investigation was to compare shear bond strength (SBS) of different adhesive resin cements and their pretreatment procedures to Titanium, Ni-Cr-Alloy (Remanium®) and Resin Nano Ceramic (RNC, Lava™ Ultimate Restorative).

Protocol: Materials tested were Multilink® Automix, Variolink® II (both Ivoclar Vivadent), Panavia™ F2.0, Clearfil™ Esthetic Cement (both Kuraray), NX3 (Kerr), RelyX™ Ultimate Adhesive Resin Cement (3M ESPE).

For shear bond strength (SBS) testing, Titanium, Remanium and RNC speci-mens were pretreated as recommended by manufacturers’ instructions. Stainless steel rods (diameter 4 mm) were cemented under standardized pressure (20 g/mm2) onto the restoration material specimens and light-cured (lc for RNC) or dark-cured (sc for Titanium, Remanium) following the manufacturers’ instructions. RelyX™ Ultimate Cement was used with Scotchbond™ Universal Adhesive (3M ESPE) that serves both as tooth bonding agent and restoration primer. Specimens were stored for 24 hours at 36 °C /96.8 °F and 100 % relative humidity. Half of the specimens were artificially aged (5,000 thermal cycles (TC), 5 °C – 55 °C (41 – 131 °F), 30 seconds dwell time). SBS was measured using a universal testing machine (Zwick Z010, crosshead speed: 0.75 mm/minute). Data obtained were analyzed using Multiple Range Test (Fisher’s LSD; p < 0.05; n = 6).

60

50

40

30

20

10

0Panavia™ F2.0/

Clearfil™ CeramicPrimer

Multilink® Automix/

Monobond Plus

NX3/Silane Primer

RelyX™ UltimateCement/Scotchbond™

Universal Adhesive

Variolink® II/Monobond

Plus

RelyX™ Ultimate/RelyX™ Ceramic

Primer

Lava™ Ultimate Ic 24h Lava™ Ultimate Ic 5000TC

SBS

(MPa

)

Bond strength of RelyX™ Ultimate Cement to resin nanoceramics (Lava™ Ultimate) in light-cure mode with/without thermocycling compared to other resin cements.


50

In vitro testing

Results:

Conclusion: RelyX™ Ultimate Adhesive Resin Cement and its dedicated pretreatment protocol with Scotchbond™ Universal Adhesive shows highest adhesion values to all tested restoration materials.


3M ESPE Comments: Using its bonding agent Scotchbond™ Universal Adhesive as a universal restoration primer, RelyX™ Ultimate Cement achieves highest bond strength to all tested restoration materials, self-cured to titanium and non-precious alloy and light-cured to Lava™ Ultimate resin nanoceramics.

Titanium sc Remanium sc Lava™ Ultimate Ic

24h 5000TC 24h 5000TC 24h 5000TC

Clearfil™ Esthetic Cement/Alloy Primer

9.8 ± 1.7a 38.5 ± 8.9b 9.5 ± 4.7? 28.1 ± 5.8? n.d. n.d.

Multilink® Automix/ Monobond Plus

38.1 ± 5.2c 36.7 ± 4.4b 35.9 ± 3.7c 27.1 ± 3.3b 29.5 ± 5.3a 44.9 ± 8.4b,c

Panavia™ F2.0/-/-/Clearfil™ Ceramic Primer

32.1 ± 2.3b 42.7 ± 8.5b 34.0 ± 2.9c 42.4 ± 6.4c 34.8 ± 6.1a,b 41.3 ± 7.1a,b

NX3/-/-/Silane Primer 31.6 ± 3.4b 19.9 ± 1.1a 25.5 ± 3.6b 15.2 ± 1.9a 38.6 ± 5.3b 47.2 ± 8.7b,c

RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive

52.1 ± 5.8d 50.9 ± 3.0c 44.3 ± 3.3d 42.0 ± 6.4c 45.3 ± 4.6c 51.2 ± 6.8c

Variolink® II/Monobond Plus

n.d. n.d. n.d. n.d. 36.7 ± 4.5b 34.3 ± 8.8a

RelyX™ Ultimate/RelyX™ Ceramic Primer

n.d. n.d. n.d. n.d. 48.9 ± 6.0c 44.5 ± 8.5b,c

60

50

40

30

20

10

0


Alloy Primer

Panavia™ F2.0/-/-/Clearfil™ Ceramic

Primer

Multilink® Automix/

Monobond Plus

NX3/-/-/Silane Primer

RelyX™ UltimateCement/Scotchbond™

Universal Adhesive

Remanium sc 24h Remanium sc 5000TC

Titanium sc 24h Titanium sc 5000TC

SBS

(MPa

)

Bond strength of RelyX™ Ultimate Cement to various metals in dark-cure mode with/without thermocycling compared to other resin cements.

Values in one column marked with the same superscript characters are not statistically different.

3.

51


RelyX™ Ultimate Cement shows reliable long-term adhesion performance to titanium in the self-cure mode

Long-term adhesion of RelyX™ Ultimate Cement to titanium Published in: Journal of Dental Research 2013, 92 (Spec. Issue B), 465

Published by: S. Hader, R. Hecht, G. Raia, and R. Guggenberger, 3M ESPE, Seefeld, Germany

The aim of the study: This study investigated long-term adhesion performance of RelyX™ Ultimate Cement to titanium in the auto-cure mode.

Protocol: Materials tested were RelyX™ Ultimate Cement in combina-tion with Scotchbond™ Universal Adhesive (SBU) both from 3M ESPE.

Shear bond strength (SBS) was tested on titanium (grade 2) slides (25 × 10 × 2 mm). Stainless steel rods (4.0 mm diameter, 2 mm height) were cemented using RelyX™ Ultimate Cement in combination with Scotchbond™ Universal Adhesive. Titanium was pretreated according to manufacturer’s instructions by sandblasting (alumina particles 50 µm). Scotchbond™ Universal Adhesive was applied for 20 sec and gently air dried for 5 sec. Stainless steel rods were cemented under pressure (20 g/mm2) onto titanium slides and cured for 10 min at 36 °C/96.8 °F. Excess was removed using a probe and remaining cement was covered with glycerol gel (AIRBLOCK™, Dentsply). Then loading weight and glycerol gel were removed. Prepared specimens were stored for 24 h at 36 °C/96.8 °F and 100 % relative humidity. SBS was measured after 24h (n = 6). Additional specimens were stored in water at 36 °C/96.8 °F for artificial aging and SBS was measured after 3, 6, and 12 months (each group n = 6). SBS was measured using a universal testing machine (Zwick Z010, crosshead speed: 0.75 mm/min). Data obtained were analyzed using Multiple Range Test (Fisher’s LSD; p < 0.05).


52

In vitro testing

Results:

Aging time SBS [MPa]

24h 41.4±2.4A

3 months 43.8±3.9A

6 months 51.1±4.5B

12 months 45.6±8.1A,B

Values marked with the same superscript characters are not statisti-cally different.

Conclusion: RelyX™ Ultimate Adhesive Resin Cement in combination with Scotchbond™ Universal Adhesive shows constantly high adhesion performance to titanium even after artificial aging up to one year in the self-cure mode. The excellent performance in the self-cure mode is a key feature for successful cementation to metal-based restorations including e.g. titanium implants.

0 180 270 360 45090

Shea

r bon

d st

reng

th [M

Pa]

Time [days]

60

50

40

30

20

10

0

3M ESPE Comments: Reliable adhesion over time to titanium in the self-cure mode is demonstrated for RelyX™ Ultimate Adhesive Resin Cement in combination with Scotchbond™ Universal Adhesive in the above test. It is a prerequisite for clinical success, e.g. for cementation to abutments/implants.

Reprinted with permission from the Journal of Dental Research 2013, J Dent Res 92 (Spec Iss B): 465

Long term adhesion of RelyX™ Ultimate Cement/ Scotchbond™ Universal Adhesive (SBU) to Titanium. Aging in water at 36 °C/96.8 °F; auto-cure mode of SBU and RelyX™ Ultimate.

3.

53


RelyX™ Ultimate Cement 3-Body-Wear resistanceAuthors: C. Kleverlaan, ACTA University, Netherlands

Available from: 3M ESPE, excerpt from study report

Aim of the study: To compare wear resistance of filling composites and adhesive resin cements in a standardized ACTA 3-body-wear test design.

Protocol: The wear rate was determined by an in vitro 3-body-wear test on the ACTA wear machine21. In this test, the material (1st body) is loaded onto a slotted wheel, which contacts a knurled wheel that acts as an “antagonistic cusp” (2nd body). The two wheels counter-rotate against one another dragging an abrasive slurry (3rd body) between them. Dimensional loss during 156,000 cycles is determined by profilometry at regular intervals of 39,000 cycles. As the wear in this method typically follows a linear pattern, the data is plotted using linear regression. The wear rates, i.e. the slope of the lines, are determined. The comparison of rates reduces some of the variability in the test due to sample preparation.

Results:

Filtek™

Z250Tetric Evo

FlowCeramXMono Multilink®

AutomixPanavia™ F2.0 NX3RelyX™

Ultimate Cement

ACTA 3-Body-Wear testing. Results after 1 week

Wea

r rel

ativ

e to

Filt

ek™

Z25

0

3

2

1

0

Wear rates of various composite materials relative to Filtek™ Z250 (3M ESPE).

4. Wear resistance

54

RelyX™ Ultimate Cement shows excellent wear resistance

Conclusion: RelyX™ Ultimate Cement showed slightly higher wear than the filling composite material Filtek™ Z250 used as a gold standard which all other materials are measured against. Wear was lower than for other composite cements and flowables tested.

3M ESPE Comments: Due to optimized filler technology RelyX™ Ultimate Cement shows high wear resistance compared to other cements and allows for good marginal stability. This is especially important for inlays where margins are exposed to chewing.

21) Pallav P, Davidson CL, deGee AJ. Wear rates of composites, amalgam and enamel under stress-bearing conditions. J. Prosthetic Dent. 59:4, 1998

4.

55

In vitro testing


Marginal fit of all-ceramic inlays luted with two-step bonding/luting systems Published in: Journal of Dental Research 2013, 92 (Spec. Issue A), 3580

Published by: R. Lang, M. Rosentritt, G. Handel, and M. Behr, Department of Prosthetic Dentistry, Regensburg University Medical Center, Regensburg, Germany

Aim of the study: The aim of the study was to investigate the in vitro marginal adaptation of all-ceramic inlays luted with a new two-step bonding/luting agent system in different curing modes and an estab-lished control material.

Protocol: Class II (MOD) ceramic inlays (n = 32, IPS Empress, Ivoclar Vivadent, FL) were luted onto human molars using Scotchbond™ Universal Adhesive/RelyX™ Ultimate Cement (SU/RU) system (3M ESPE, D) as follows: SU/RU 1: No etch (NE), bonding dark-cured (DC), luting agent light-cured (LC); SU/RU 2: No etch (NE), bonding dark-cured (DC), luting agent dark-cured (DC); SU/RU 3: Total-etch (TE), bonding dark-cured (DC), luting agent light-cured (LC); MA (Multilink® Automix, Ivoclar Vivadent, FL) as control. After 14 days of storage in water (37 ° C/98.6 °F) and subsequent thermal cycling with mechanical loading (TCML, 1.2 × 106 × 50 N, 2 × 3,000 × 5 °/55 °C (41/141 °F), 1.6 Hz) the marginal adaptation was determined by dye penetration test (0.5 % Fuchsine, 16 hours 37 °C /98.6 °F). The marginal adaptation of each tooth was evaluated at dentin and enamel margins at the interface between tooth and cement using a microscope (25×) (Zeiss, D) and the image analysis system (Optimas inc., USA). Dye penetration was calculated as the relation between “length of the prepared step” to “length of the penetrated dye”. Statistics: Mann – Whitney U-Test (a = 0.05).

5. Marginal seal

56

RelyX™ Ultimate Cement shows excellent marginal seal

Results:

Conclusion: RelyX™ Ultimate Cement/Scotchbond™ Universal Adhesive groups had significantly lower dye penetration than the control Multilink® Automix. The curing mode did influence the dye penetration results and should be considered in clinical practice.

3M ESPE Comments: RelyX™ Ultimate Cement / Scotchbond™ Universal Adhesive shows lower dye penetration than the Multilink® Automix adhesive system.


Bonding/ Luting Agent System

Margin Mean % Penetration (Standard Error of Mean)

SU/RU1 (NE/DC/LC) Dentin 23.41 (5.76)

Enamel 13.52 (5.85)

SU/RU2 (NE/DC/DC) Dentin 11.52 (4.70)

Enamel 7.68 (3.91)

SU/RU3 (TE/DC/LC) Dentin 5.45 (2.37)

Enamel 14.87 (5.93)

MA Control (Primer A&B) Dentin 37.78 (7.68)

Enamel 33.99 (7.62)

Inlay margin in dentin, self-etch approach, RelyX™ Ultimate Cement and Scotchbond™ Universal Adhesive dark-cured only.

restoration

embedding material

tooth

5.

57

In vitro testing


Color stability of adhesive resin cementsPublished in: Journal of Dental Research 2014, 93 (Spec. Issue B), 566

Published by: S. Hader, R. Hecht, G. Raia, C. Thalacker, M. Ludsteck, 3M ESPE, Seefeld, Germany

Aim of the study: The long-term color stability is an important feature of esthetic resin cements. In this in vitro investigation different adhesive resin cements were compared regarding their stability against exogenic staining.

Protocol: Materials tested were RelyX™ Ultimate Cement “A1” (3M ESPE) [RXU], Variolink® II “universal” (Ivoclar Vivadent) [V2], Variolink® Veneer “low value 2” (Ivoclar Vivadent) [VV], Panavia™ F2.0 “light” (Kuraray) [PanF], NX3 “yellow” (Kerr) [NX3]. Stability against exogenic staining was investigated by incubating light-cured cement specimens (Ø15 mm, h = 1.5 mm) in coffee solution (1 part coffee:5 parts deionised water) or in a ketchup-mustard-water mixture (12.5:12.5:75 parts) at 36 °C/96.8 °F for 7d, respectively. Color was measured before and after incubation using a spectral photometer Color i7 (x-rite) and dif-ferences (CIE ΔE*) were calculated. Data obtained were analyzed using Multiple RangeTest (Fisher’s LSD; p < 0.05).

Results:

Coffee-Test Ketchup-Mustard-Test

RelyX™ Ultimate Cement [RXU] 4.7 ± 0.1D 24.8 ± 3.4B

Variolink® II [V2] 8.7 ± 0.1B 22.4 ± 1.6B

Variolink® Veneer [VV] 5.1 ± 0.5D 21.9 ± 3.7B

Panavia™ F2.0 [PanF] 17.2 ± 0.5A 40.7 ± 9.2A

NX3 [NX] 6.1 ± 0.5C 31.2 ± 6.0A,B

Values within one column marked with the same superscript characters are not statistically different.

6. Esthetics

58

RelyX™ Ultimate Cement shows high resistance to exogenic staining

Conclusion: The RelyX™ Ultimate Adhesive Resin Cement shows the lowest discoloration of tested resin cements in the coffee test and is even comparable to the veneer cement. All resin cements show a higher discoloration in the ketchup-mustard-test.

3M ESPE Comments: Due to its unique chemistry, RelyX™ Ultimate Cement has lower discoloration than many other resin cements after exposure to food staining solutions.

Reprinted with permission from the Journal of Dental Research 2014, J Dent Res 93 (Spec Iss B):566

Coffee test

RelyX™ UltimateCement

Variolink® Veneer Panavia™ F2.0 NX3Variolink® II

201816141210

86420

CIE

ΔE*

Ketchup-mustard-test

RelyX™ UltimateCement

Variolink® Veneer Panavia™ F2.0 NX3Variolink® II

60

50

40

30

20

10

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CIE

ΔE*

6.

59

In vitro testing


Fluorescence levels of different resin cements compared to human toothAvailable from: 3M ESPE internal data

Aim of the study: To visualize fluorescence levels of different resin cements compared to human tooth.

Protocol and results: Samples of 1.5 mm thickness and a diameter of 15 mm were exposed to UV-A irradiation.

Conclusion: RelyX™ Ultimate Cement has tooth-like fluorescence and esthetics.

3M ESPE Summary: RelyX™ Ultimate Cement /Scotchbond™ Universal Adhesive not only displays high bond strength but also tooth-like esthetics, making it a preferred recommendation for cementing modern esthetic ceramic restorations.

Fluorescence comparison of RelyX™ Ultimate Cement (left, shade: transparent) with human incisor (right). Picture courtesy of Dr. Paulo Monteiro, Portugal.

Tooth-like fluorescence

Human Tooth

RelyX™ Ultimate

Panavia™ F2.0

NX3

Clearfil Esthetic Cement

6. Esthetics

60

RelyX™ has natural tooth-like fluorescence

Handling guide reference and Clicker™ Dispenser

Handling guide reference

For detailed information and step-by-step instructions please go to:

www.3MESPE.com/RelyXUltimate

Download the PDF of the step-by-step brochure:

Handling guide reference and Clicker™ Dispenser

62

Clicker™ Dispenser

In some countries RelyX™ Ultimate Cement is solely or additionally avail-able in the Clicker™ Dispenser. Several studies prove that the different delivery systems – automix syringe or Clicker™ Dispenser – do not have any influence on the performance of the product.

For further reading:

Page 24 – 25: Bond strength of Adhesive Resin Cements to Enamel and Dentin. A. Piwowarczyk, S. Ernst, W.H. Arnold and E.A. Naumova: University of Witten/Herdecke, Witten, Germany. Journal of Dental Research 2013, 92 (Spec. Issue A), 1058

Page 28 – 29: Shear Bondstrength of Resin Cements to Dentin and Enamel. J. Bair, S. Bhatt, R.D. Perry and G. Kugel: School of Dental Medicine, Tufts University, Boston, MA. Journal of Dental Research 2013, 92 (Spec. Issue A), 3042

63


References

Anonymous: RelyX™ Ultimate Adhesive Resin Cement. Technical Data Sheet, 3M ESPE 2012 9

Anonymous: RelyX ™ Ultimate Adhesive Resin Cement. Reality Now, November-December 2012, 238 12

Anonymous: 3M ESPE RelyX™ Ultimate Adhesive Resin Cement. The Dental Advisor 2012, Vol. 29, No. 5 12

Anonymous: RelyX ™ Ultimate Adhesive Resin Cement – Two-year clinical performance. The Dental Advisor, March 2014 16

J. Bair, S. Bhatt, R. D. Perry, and G. Kugel: Shear bond strength of resin cements to dentin and enamel. Journal of Dental Research 2013, 92 (Spec. Issue A), 3042 28

C. D. Benitez, A.L. Fernandez, M. Finkelman, R. Ritter, M. Harsono, and G. Kugel: SBS of lithium disilicate and zirconia ceramic luted to dentin. Journal of Dental Research 2013, 92 (Spec. Issue A), 1088 42

F. J. Trevor Burke, Russell J. Crisp: The PREP Panel evaluates 3M ESPE´s RelyX™ Ultimate Adhesive Resin Cement. The Dentist 2013, 54-58 13

R.J. Crisp, and F.T. Burke: Innovative colour matched multi-purpose resin based cementation system evaluated by general practitioners. Journal of Dental Research 2012,90 (Spec. Issue A), 979 12

Q. Cai, D. Cakir, P. Beck, L. Ramp, and J. Burgess: Retention of zirconia crowns bonded with adhesive resin cements. Journal of Dental Research 2012, 91 (Spec. Issue A), 1010 38

R. J. Crisp, F. J. T. Burke: Innovative colour matched multi-purpose resin based cementation system evaluated by general practitioners. Journal of Dental Research 2011, 90 (Spec. Issue A), 979 12

C. Decoteau, M. Oglezki, G. Kugel, and R.D. Perry:Bond strength of multi-step cements to enamel and zirconia. Journal of Dental Research 2011, 90 (Spec. Issue A), 375 37

References

66

D. J. Fasbinder, G.F. Neiva, J.B. Dennison, D. Heys, and R. Heys: One-year evaluation of CAD/CAM nano-ceramic and leucite-reinforced onlays. Journal of Dental Research 2014, 93 (Spec. Issue A), 100 14

S. Hader, R. Hecht, G. Raia, and R. Guggenberger: Long-term adhesion of RelyX ™ Ultimate Cement to titanium. Journal of Dental Research 2013, 92 (Spec. Issue B), 465 52

S. Hader, R. Hecht, G. Raia, C. Thalacker, and R. Guggenberger: RelyX ™ Ultimate Adhesive Resin Cement adhesion to etchable glass ceramics. Journal of Dental Research 2013, 92 (Spec. Issue A), 1090 48

S. Hader, R. Hecht, G. Raia, C. Thalacker, and M. Ludsteck: Adhesion of adhesive resin cements to dentin. Journal of Dental Research 2014, 93 (Spec. Issue A), 1129 36

S. Hader, R. Hecht, G. Raia, C. Thalacker, M. Ludsteck: Color stability of adhesive resin cements. Journal of Dental Research 2014, 93 (Spec. Issue B), 566 58

R. Lang, M. Rosentritt, G. Handel, and M. Behr: Marginal fit of all-ceramic inlays luted with two-step bonding/luting systems. Journal of Dental Research 2013, 92 (Spec. Issue A), 3580 56

P. Nelson, R.A. Yapp, and J.M. Powers: Bond strength of RelyX ™ Ultimate Cement/Scotchbond™ Universal Adhesive. Journal of Dental Research 2013, 92 (Spec. Issue A), 1053 20

A. Piwowarczyk, S. Ernst, W. H. Arnold, and E. A. Naumova: Bond strength of adhesive resin cements to enamel and dentin. Journal of Dental Research 2013, 92 (Spec. Issue A), 1058 24

A. Piwowarczyk, S. Ernst, W. H. Arnold, E. A. Naumova: Long-term bond strength of resin cements to enamel and dentin. Journal of Dental Research J. Dent. Res. 2014, 93 (Spec. Issue C), 401 34

S. Saboree, A. Perera, M. Harsono, M. Finkelman, and G. Kugel: Shear bond strength of self-adhesive resin cement above/below CEJ. Journal of Dental Research 2013, 92 (Spec. Issue A), 1059 22

67


G. Turco, A. Frassetto, G. Marchesi, I. Spagnolo, C. Navarra, R. di Lenarda, M. Cadenaro, and L. Breschi: Adhesion of indirect ceramic and composite restorations: influence of chewing. Journal of Dental Research 2012, 91 (Spec Issue. A), 1300 40

C. Thalacker, G. Raia, R. Hecht, S. Hader, and D. Krueger: Adhesion to saliva contaminated zirconia cleaned with different methods. Journal of Dental Research 2014, 93 (Spec. Issue A), 169 46

C. Wiedig, R. Hecht, G. Raia, M. Ludsteck, and R. Guggenberger: Shear bond strength of adhesive resin cements to enamel and dentin. Journal of Dental Research 2011, 90 (Spec. Issue B), 430 26

C. A. Wiedig, R. Hecht, G. Raia, M. Ludsteck, and C. Thalacker: Shear bond strength of adhesive resin cements to different restoration materials. Journal of Dental Research 2012, 91 (Spec. Issue A), 641 50

References

68

3M ESPE, Seefeld, Germany, data on file:

Anonymous: Fluorescence levels of different resin cements compared to human tooth 60

Anonymous: RelyX ™ Ultimate Cement – Adhesion to moist and dry dentin 32

Anonymous: RelyX ™ Ultimate Cement – Clinical use including post-operative sensitivity. 3M ESPE Field evaluation 13

Anonymous: Shear bond strength of RelyX ™ Ultimate Cement 5 minutes after curing 30

C. Kleverlaan: RelyX ™ Ultimate Cement 3-Body-Wear resistance. 54

F. Lehmann, M. Kern: RelyX ™ Ultimate Cement – Bonding durability to zirconia compared to other resin cements 44

Y. Suyama, B. Van Meerbeek: RelyX ™ Ultimate Cement – Microtensile bond strength to bur cut dentin and enamel 37

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Notes

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3M Deutschland GmbHLocation Seefeld 3M ESPE · ESPE Platz82229 Seefeld · [email protected]

3M, ESPE, Clicker, CoJet, Elipar, Filtek, Lava, RelyX, Rocatec and Scotchbond are trademarks of 3M Company or 3M Deutschland GmbH. Used under license in Canada.All other trademarks are owned by other companies.© 2015, 3M. All rights reserved.01 (01.2015)

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