Relevance The processing of internally generated...
6
1 June 20, 2009 The processing of internally generated interoceptive sensation Human Brain Mapping, 2009 Craig Bennett University of California, Santa Barbara June 20, 2009 2 Relevance • Interoception is understudied • The development of interoception is understudied • The dysfunction of interoception is understudied • Insular function is not well understood June 20, 2009 3 On Mind and Body Baruch Spinoza René Descartes Aristotle William James Charles Darwin Walter Cannon June 20, 2009 4 Interoception and the Insula June 20, 2009 5 Interoception: the current homeostatic condition of the entire body and the ability for this information to reach conscious awareness Sherrington, 1906; Craig, 2003 June 20, 2009 6 The Insula
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Transcript of Relevance The processing of internally generated...
1
June 20, 2009
The processing of internally generated interoceptive sensation
Human Brain Mapping, 2009
Craig BennettUniversity of California, Santa Barbara
June 20, 2009
2
Relevance
• Interoception is understudied
• The development of interoception is understudied
• The dysfunction of interoception is understudied
• Insular function is not well understood
June 20, 2009
3
On Mind and Body
Baruch SpinozaRené DescartesAristotle
William JamesCharles Darwin Walter Cannon
June 20, 2009
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Interoception and the Insula
June 20, 2009
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Interoception: the current homeostatic condition of theentire body and the ability for this information to reach consciousawareness
Sherrington, 1906; Craig, 2003
June 20, 2009
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The Insula
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June 20, 2009
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The Insula
Penfield, 1955
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The Insula
Naidich et al., 2004
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Posterior Insula
Craig, 2004 Craig, 2000
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Posterior Insula
Hua et al., 2005
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Mid Insula
Hadjikhani et al., 1998 Banati et al., 2000 Bushara et al., 2001
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Anterior Insula
Craig, 2000 Critchley et al., 2004
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Anterior Insula
Dosenbach et al., 2006 Sridharan et al., 2008
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The Insula
Here there be dragons…
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Our Experiment
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Mental Imagery
Kraemer et al., 2005 Kosslyn et al., 2001Slotnick et al., 2005
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Example Phrases
Freezing Cold
Sweltering Hot
Starving Hunger
Nauseous
Itchy Rash
Internal States
Tie Shoes
Pour Water
Wash Hands
Lock Door
Answer Phone
Everyday Actions
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Results: General Imagery
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Results: Action Imagery
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Results: Action Imagery
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Results: Interoceptive Imagery
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Results: Interoceptive Imagery
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Interim Conclusions
The interoceptive system can be driven in
a top-down manner through mental imagery
Only secondary areas of interoceptive cortex
showed significant activity
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Interoceptive Development
5
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Cortical Development
Giedd et al., 1999 Gogtay et al., 2004
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Cortical Development
Shaw et al., 2008
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Results: Amodal Developmental Differences
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Results: General Developmental Differences
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Results: Internal ROI Changes
Internal > Action, Adult ROIs
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Developmental Conclusions
Regions of higher-order cortex showdevelopmental differences in activity duringmental imagery
Regions active during internal imagery inadults were hypoactive in adolescents
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Final Conclusions
There is still much to investigate and explore
Mental imagery can be used to explore interoception
Areas supporting this processing are still developing
Interoceptive sensory processing is separable, unique
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Thank You
bennett @ psych.ucsb.edu
http://prefrontal.org
