Regulation of Enzyme Activity - bio-net.us · Regulation of Enzyme Activity Author: Kelcey Burris...
Transcript of Regulation of Enzyme Activity - bio-net.us · Regulation of Enzyme Activity Author: Kelcey Burris...
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REGULATION OF ENZYME ACTIVITY
Interactions between molecules affect their structure and function.
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Other Molecules Can Affect Enzyme Structure and Function.
Competitive Inhibition:
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Non-Competitive Inhibition
“Allosteric Interaction”: Affects enzyme structure through binding away from the active site.
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Allosteric Interactions allow for feedback inhibition of metabolism
Ex. ATP inhibits the activity of phosphofructokinase.
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The local environment can affect the shape of the enzyme, which will affect its function.
Ex. Temperature
and pH.
Environmental Influences on Enzyme Function
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The concentration of enzyme and substrate will also affect enzyme function.
Concentration Influences on Enzyme Function
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Enzyme Activity can be measured in different ways:Appearance of a product
Disappearance of a substrate
Indirect Analogs: Ex. Color Change, Change in Temp.
Measuring Enzyme Activity