Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

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Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

Transcript of Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

Page 1: Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

Regents Biology

Mitosis & Cancer:When Making New Cells

Goes Terribly Wrong!

Page 2: Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

Regents Biology

When is mitosis a good thing? When you have to add or replace cells

growth & development repair replacement

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Regents Biology

Regulation of Cell Cycle

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Regents Biology

Cells will not divide if…

there are not enough nutrients to support cell growth

DNA is damagedDNA has not been replicated

…cell will be repaired / destroyed.

Page 5: Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

Regents Biology

When is mitosis a BAD thing When cells reproduce & they are not

needed these cells take over organs, but don’t

do the right job they just keep making copies cancer

damages organs

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Regents Biology

Growth of a tumor

Page 7: Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

Regents Biology

Healthy Cells grow in a single

layer stop dividing

when they receive messages from neighbouring cells

Cancer Cells do not respond to

messages from neighbouring cells…continue to divide

start to grow in multiple layers that form a tumor

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Regents Biology

Why would cells just make copies?

If DNA gets damaged, cells stop listening to correct instructions mutations

Causes of mutations: UV radiation chemical exposure radiation exposure heat

cigarette smoke pollution age genetics

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Tumors Benign tumor

abnormal cells remain at original site as a lump

most do not cause serious problems &can be removed by surgery

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Tumors Malignant tumor

cells leave original site carried by blood system to other tissues start more tumors

damage functions of organs throughout body

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Watch how a tumor grows...

http://www.hhmi.org/biointeractive/media/angiogenesis-lg.mov

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Regents Biology

Treatments for cancers Treatments kill rapidly dividing cells

chemotherapy poisonous drugs that kill rapidly dividing cells

radiation high energy beam kills rapidly dividing cells

side effects

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Regents Biology 2009-2010

Show what you’ve learned!

Assignment:

Page 138 Questions14 to18