MAKE IT SIMPLE®

© MIS Corporation. All Rights Reserved.

®

MC-FREGS Rev. 4

REGENERATIVE SOLUTIONS

4BONE Plug and 4BONE Tape are dental wound dressings used following oral surgical procedures to control bleeding, stabilize blood clots and aid in wound healing. Both 4BONE Plug and 4BONE Tape are fully resorbable and are engineered from highly purified cross-linked Type I bovine collagen with an optimal structure and thickness to allow the absorption of both fluid and blood at the defect site.

DENTAL WOUND

DRESSINGS

4BONE Tape

4BONE Plug

4BONE BCH Syringe

4BONE BCH Tube

4BONE BCH is a fully synthetic bioactive bone substitute composed of chemical synthesis of 60% HA and 40% ß-TCP. With its micro and macro porosity and osteoconductive properties, BCH attracts osteogenic cells and promotes the diffusion of biological fluids, providing a guaranteed homogenous distribution and diffusion of the two phases. 4BONE provides flexibility and a predictable healing process and outcome for a wide range of bone regeneration procedures.

SYNTHETIC BONE

GRAFT

MIS Implants Technologies Ltd. www.mis-implants.com

RCB RNB

BOND BONE

TAPE

PLUG

BCH

XBM

RCM

RCBRSB

Optimal volumes and quality of hard and soft tissue

are required to satisfy the goals of implant dentistry.

MIS offers a range of high quality regenerative

materials aimed at providing solutions for a wide

variety of clinical needs. MIS regenerative products

are packed in varying weights and volumes, for

simple and easy delivery directly to the surgical

site. High quality engineering and manufacturing

processes ensure safety of all MIS products. The

variety of regenerative solutions offered by MIS

allows clinicians to choose the precise products

necessary to obtain the optimal surgical outcome.

4BONE XBM is an anorganic bovine bone mineral matrix for use in bone regeneration procedures. XBM is recommended for use by clinicians for regenerating new bone in periodontal defects and dental implant therapy. The natural bone minerals are isolated from bovine bone and produce an osteoconductive material for bone regeneration. Due to its natural structure, XBM is physically and chemically comparable to the mineralized matrix of human bone. The trabecular architecture with interconnecting macro and micro pores allows for the optimal ingrowth of new vascularity and bone at the graft site and maximizes the potential for angiogenesis.

ANORGANIC BOVINE BONE

MATRIX4BONE Collagen Barrier Membranes are bioresorbable, cell occlusive barriers used in guided tissue and guided bone regeneration procedures to aid in wound healing in the areas of dental implants, bone defects and ridge augmentation. 4BONE barrier membranes are fully resorbable, eliminating the need for an additional surgical procedure. The membranes’ semi-permeability properties permit the exchange of essential nutrients for wound healing while the porosity qualities effectively prevent penetration of epithelial cells into the wound site. Unique engineering processes enable excellent handling properties for ease of placement and suturing as well as optimal resorption rate for sustained function in bone repair.

RESORBABLE COLLAGEN

MEMBRANES

4BONE RSB

4BONE XBM

BOND BONE®

BONDBONE is a novel synthetic bone grafting material, a breakthrough in the field of dental bone regeneration. BONDBONE is based on pure biphasic calcium sulfate, well-established and widely documented for its biocompatibility, osteoconductivity and bioresorbability. Biphasic calcium sulfate sets fast and its physical properties are not affected by the presence of

blood and saliva. BONDBONE is the ultimate binder for most bone graft substitutes, regardless of origin. BONDBONE allows easy handling and reduces procedure time. Its

unique porous structure allows rapid vascularization and penetration

of growth factors and cells through its micro pores. BONDBONE can also be used alone in socket preservation procedures, after immediate implant placement and for the augmentation of other small defects.

BONDING GRAFT

MATERIAL

® MAKE IT SIMPLE

TM

RCB RNB

BOND BONE

TAPE

PLUG

BCH

XBM

RCM

RCBRSB

Optimal volumes and quality of hard and soft tissue

are required to satisfy the goals of implant dentistry.

MIS offers a range of high quality regenerative

materials aimed at providing solutions for a wide

variety of clinical needs. MIS regenerative products

are packed in varying weights and volumes, for

simple and easy delivery directly to the surgical

site. High quality engineering and manufacturing

processes ensure safety of all MIS products. The

variety of regenerative solutions offered by MIS

allows clinicians to choose the precise products

necessary to obtain the optimal surgical outcome.

4BONE XBM is an anorganic bovine bone mineral matrix for use in bone regeneration procedures. XBM is recommended for use by clinicians for regenerating new bone in periodontal defects and dental implant therapy. The natural bone minerals are isolated from bovine bone and produce an osteoconductive material for bone regeneration. Due to its natural structure, XBM is physically and chemically comparable to the mineralized matrix of human bone. The trabecular architecture with interconnecting macro and micro pores allows for the optimal ingrowth of new vascularity and bone at the graft site and maximizes the potential for angiogenesis.

ANORGANIC BOVINE BONE

MATRIX4BONE Collagen Barrier Membranes are bioresorbable, cell occlusive barriers used in guided tissue and guided bone regeneration procedures to aid in wound healing in the areas of dental implants, bone defects and ridge augmentation. 4BONE barrier membranes are fully resorbable, eliminating the need for an additional surgical procedure. The membranes’ semi-permeability properties permit the exchange of essential nutrients for wound healing while the porosity qualities effectively prevent penetration of epithelial cells into the wound site. Unique engineering processes enable excellent handling properties for ease of placement and suturing as well as optimal resorption rate for sustained function in bone repair.

RESORBABLE COLLAGEN

MEMBRANES

4BONE RSB

4BONE XBM

BOND BONE®

BONDBONE is a novel synthetic bone grafting material, a breakthrough in the field of dental bone regeneration. BONDBONE is based on pure biphasic calcium sulfate, well-established and widely documented for its biocompatibility, osteoconductivity and bioresorbability. Biphasic calcium sulfate sets fast and its physical properties are not affected by the presence of

blood and saliva. BONDBONE is the ultimate binder for most bone graft substitutes, regardless of origin. BONDBONE allows easy handling and reduces procedure time. Its

unique porous structure allows rapid vascularization and penetration

of growth factors and cells through its micro pores. BONDBONE can also be used alone in socket preservation procedures, after immediate implant placement and for the augmentation of other small defects.

BONDING GRAFT

MATERIAL

® MAKE IT SIMPLE

TM

RCB RNB

BOND BONE

TAPE

PLUG

BCH

XBM

RCM

RCBRSB

Optimal volumes and quality of hard and soft tissue

are required to satisfy the goals of implant dentistry.

MIS offers a range of high quality regenerative

materials aimed at providing solutions for a wide

variety of clinical needs. MIS regenerative products

are packed in varying weights and volumes, for

simple and easy delivery directly to the surgical

site. High quality engineering and manufacturing

processes ensure safety of all MIS products. The

variety of regenerative solutions offered by MIS

allows clinicians to choose the precise products

necessary to obtain the optimal surgical outcome.

4BONE XBM is an anorganic bovine bone mineral matrix for use in bone regeneration procedures. XBM is recommended for use by clinicians for regenerating new bone in periodontal defects and dental implant therapy. The natural bone minerals are isolated from bovine bone and produce an osteoconductive material for bone regeneration. Due to its natural structure, XBM is physically and chemically comparable to the mineralized matrix of human bone. The trabecular architecture with interconnecting macro and micro pores allows for the optimal ingrowth of new vascularity and bone at the graft site and maximizes the potential for angiogenesis.

ANORGANIC BOVINE BONE

MATRIX4BONE Collagen Barrier Membranes are bioresorbable, cell occlusive barriers used in guided tissue and guided bone regeneration procedures to aid in wound healing in the areas of dental implants, bone defects and ridge augmentation. 4BONE barrier membranes are fully resorbable, eliminating the need for an additional surgical procedure. The membranes’ semi-permeability properties permit the exchange of essential nutrients for wound healing while the porosity qualities effectively prevent penetration of epithelial cells into the wound site. Unique engineering processes enable excellent handling properties for ease of placement and suturing as well as optimal resorption rate for sustained function in bone repair.

RESORBABLE COLLAGEN

MEMBRANES

4BONE RSB

4BONE XBM

BOND BONE®

BONDBONE is a novel synthetic bone grafting material, a breakthrough in the field of dental bone regeneration. BONDBONE is based on pure biphasic calcium sulfate, well-established and widely documented for its biocompatibility, osteoconductivity and bioresorbability. Biphasic calcium sulfate sets fast and its physical properties are not affected by the presence of

blood and saliva. BONDBONE is the ultimate binder for most bone graft substitutes, regardless of origin. BONDBONE allows easy handling and reduces procedure time. Its

unique porous structure allows rapid vascularization and penetration

of growth factors and cells through its micro pores. BONDBONE can also be used alone in socket preservation procedures, after immediate implant placement and for the augmentation of other small defects.

BONDING GRAFT

MATERIAL

® MAKE IT SIMPLE

TM

RCB RNB

BOND BONE

TAPE

PLUG

BCH

XBM

RCM

RCBRSB

Optimal volumes and quality of hard and soft tissue

are required to satisfy the goals of implant dentistry.

MIS offers a range of high quality regenerative

materials aimed at providing solutions for a wide

variety of clinical needs. MIS regenerative products

are packed in varying weights and volumes, for

simple and easy delivery directly to the surgical

site. High quality engineering and manufacturing

processes ensure safety of all MIS products. The

variety of regenerative solutions offered by MIS

allows clinicians to choose the precise products

necessary to obtain the optimal surgical outcome.

4BONE XBM is an anorganic bovine bone mineral matrix for use in bone regeneration procedures. XBM is recommended for use by clinicians for regenerating new bone in periodontal defects and dental implant therapy. The natural bone minerals are isolated from bovine bone and produce an osteoconductive material for bone regeneration. Due to its natural structure, XBM is physically and chemically comparable to the mineralized matrix of human bone. The trabecular architecture with interconnecting macro and micro pores allows for the optimal ingrowth of new vascularity and bone at the graft site and maximizes the potential for angiogenesis.

ANORGANIC BOVINE BONE

MATRIX4BONE Collagen Barrier Membranes are bioresorbable, cell occlusive barriers used in guided tissue and guided bone regeneration procedures to aid in wound healing in the areas of dental implants, bone defects and ridge augmentation. 4BONE barrier membranes are fully resorbable, eliminating the need for an additional surgical procedure. The membranes’ semi-permeability properties permit the exchange of essential nutrients for wound healing while the porosity qualities effectively prevent penetration of epithelial cells into the wound site. Unique engineering processes enable excellent handling properties for ease of placement and suturing as well as optimal resorption rate for sustained function in bone repair.

RESORBABLE COLLAGEN

MEMBRANES

4BONE RSB

4BONE XBM

BOND BONE®

BONDBONE is a novel synthetic bone grafting material, a breakthrough in the field of dental bone regeneration. BONDBONE is based on pure biphasic calcium sulfate, well-established and widely documented for its biocompatibility, osteoconductivity and bioresorbability. Biphasic calcium sulfate sets fast and its physical properties are not affected by the presence of

blood and saliva. BONDBONE is the ultimate binder for most bone graft substitutes, regardless of origin. BONDBONE allows easy handling and reduces procedure time. Its

unique porous structure allows rapid vascularization and penetration

of growth factors and cells through its micro pores. BONDBONE can also be used alone in socket preservation procedures, after immediate implant placement and for the augmentation of other small defects.

BONDING GRAFT

MATERIAL

® MAKE IT SIMPLE

TM

MAKE IT SIMPLE®

© MIS Corporation. All Rights Reserved.

®

MC-FREGS Rev. 4

REGENERATIVE SOLUTIONS

4BONE Plug and 4BONE Tape are dental wound dressings used following oral surgical procedures to control bleeding, stabilize blood clots and aid in wound healing. Both 4BONE Plug and 4BONE Tape are fully resorbable and are engineered from highly purified cross-linked Type I bovine collagen with an optimal structure and thickness to allow the absorption of both fluid and blood at the defect site.

DENTAL WOUND

DRESSINGS

4BONE Tape

4BONE Plug

4BONE BCH Syringe

4BONE BCH Tube

4BONE BCH is a fully synthetic bioactive bone substitute composed of chemical synthesis of 60% HA and 40% ß-TCP. With its micro and macro porosity and osteoconductive properties, BCH attracts osteogenic cells and promotes the diffusion of biological fluids, providing a guaranteed homogenous distribution and diffusion of the two phases. 4BONE provides flexibility and a predictable healing process and outcome for a wide range of bone regeneration procedures.

SYNTHETIC BONE

GRAFT

MIS Implants Technologies Ltd. www.mis-implants.com

MAKE IT SIMPLE®

© MIS Corporation. All Rights Reserved.

®

MC-FREGS Rev. 4

REGENERATIVE SOLUTIONS

4BONE Plug and 4BONE Tape are dental wound dressings used following oral surgical procedures to control bleeding, stabilize blood clots and aid in wound healing. Both 4BONE Plug and 4BONE Tape are fully resorbable and are engineered from highly purified cross-linked Type I bovine collagen with an optimal structure and thickness to allow the absorption of both fluid and blood at the defect site.

DENTAL WOUND

DRESSINGS

4BONE Tape

4BONE Plug

4BONE BCH Syringe

4BONE BCH Tube

4BONE BCH is a fully synthetic bioactive bone substitute composed of chemical synthesis of 60% HA and 40% ß-TCP. With its micro and macro porosity and osteoconductive properties, BCH attracts osteogenic cells and promotes the diffusion of biological fluids, providing a guaranteed homogenous distribution and diffusion of the two phases. 4BONE provides flexibility and a predictable healing process and outcome for a wide range of bone regeneration procedures.

SYNTHETIC BONE

GRAFT

MIS Implants Technologies Ltd. www.mis-implants.com

MAKE IT SIMPLE®

© MIS Corporation. All Rights Reserved.

®

MC-FREGS Rev. 4

REGENERATIVE SOLUTIONS

4BONE Plug and 4BONE Tape are dental wound dressings used following oral surgical procedures to control bleeding, stabilize blood clots and aid in wound healing. Both 4BONE Plug and 4BONE Tape are fully resorbable and are engineered from highly purified cross-linked Type I bovine collagen with an optimal structure and thickness to allow the absorption of both fluid and blood at the defect site.

DENTAL WOUND

DRESSINGS

4BONE Tape

4BONE Plug

4BONE BCH Syringe

4BONE BCH Tube

4BONE BCH is a fully synthetic bioactive bone substitute composed of chemical synthesis of 60% HA and 40% ß-TCP. With its micro and macro porosity and osteoconductive properties, BCH attracts osteogenic cells and promotes the diffusion of biological fluids, providing a guaranteed homogenous distribution and diffusion of the two phases. 4BONE provides flexibility and a predictable healing process and outcome for a wide range of bone regeneration procedures.

SYNTHETIC BONE

GRAFT

MIS Implants Technologies Ltd. www.mis-implants.com