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OLEH :

Rachma Susteriana Putri201320401011103

PEMBIMBING :

dr H! Buih "marti#i$ S%&& 

RE'ER"( S("PH)LO*O**"LS*"L+E+ S&IN S)N+ROME

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PEN+"H,L,"N

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 (IN-","N P,S("&"

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+E'INISI

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EPI+EMIOLOGI

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PATOFISIOLOGIToksin eksfoliatif (Ets) serin protease

Toksin berdifusi dari fokus infeksi

Tidak ada antibodi antitoksin spesifik 

Proliferasi dan penyebaran di bawah barier kulit

Penyebaran toksin seara

he!ato"en ke kulit

#eni!bulkan $elah pada ikatan adhesi antar sel !olekul

des!o"lein % pada ba"ian atas epider!is (antara stratu!

spinosu! dan "ranulosu!

&ula berdindin" tipis !udah peah

 'ikolsky si"n ()

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M"NI'ES("SI &LINIS

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Ga!bar 'ikolsky*s si"n positif

 pada penderita SSSS

Ga!bar I!peti"o bulosa+ &ula

diisi airan keruh dan ke!udian

 peah !en,adi erosi dan krusta

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Ga!bar (A) berak ke!erahan yan" !enyebar

 pada len"an- !uka dan badan bayi penderita

SSSS- (&) bula berdindin" tipis yan" peah dan

!enin""alkan kesan terbakar 

" B

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Ga!bar Luka yan" telah !en"erin"

dan !ulai ter,adi deskua!asi

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+I"GNOSIS

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Gam.ar : Hist/%at//i SSSS$ dimanahianna adhesi se %ada e%idermis

su%ersia

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+I"GNOSIS B"N+ING

NETNET   SSSSSSSS

.sia pasien.sia pasien / tu/ tuaa / !uda/ !uda

Lesi tar"etLesi tar"et Serin" dite!ukanSerin" dite!ukan Tidak adaTidak ada

 'yeri kulit 'yeri kulit 0in"an sp sedan"0in"an sp sedan" San"at nyeriSan"at nyeri

Lesi oralLesi oral .!u!nya ada.!u!nya ada 1aran"1aran"

TandaTanda  Nikolsky Nikolsky () hanya di daerah lesi() hanya di daerah lesi () pada lesi 2 klt (')() pada lesi 2 klt (')

3era,at eksudasi3era,at eksudasi 4 (ta!pak der!is)4 (ta!pak der!is) % (ta!pak epder!is% (ta!pak epder!is

superfisial)superfisial)

Penye!buhanPenye!buhan / la!a/ la!a %5 6 %4 hari%5 6 %4 hari

1arin"an parut1arin"an parut Sr" dite!ukan- dpt disertaiSr" dite!ukan- dpt disertai

hiper 7 hipopi"!entasihiper 7 hipopi"!entasi1aran"1aran"

#ortalitas#ortalitas Tin""i (85 6 95 :)Tin""i (85 6 95 :) 0endah- u!u!nya se!buh0endah- u!u!nya se!buh

spontanspontan

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PENATALAKSANAAN

 (u!uan (era%i  untu meneradiasi in5esi S. Aureus

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MONI(ORING

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&/m%iasi dan Pr/n/sis

&/m%iasi %ain .erat an da%at ter!adi %ada%asien SSSS adaah anuan eseim.anan cairandan eetr/it&asus SSSS %ada ana !aran mene.a.an se%sis

sehina ana ematianna e.ih rendah 61789"na ematian %ada de#asa e.ih .esar 6menca%ai807;09 arena diiuti .e.era%a 5at/r %ene.a.ematian ainna dan %eninatan e!adian se%sis

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B"B 3 &ESIMP,L"N +"NPEN,(,P

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 (ERIM" &"SIH