Alana L. Reed, PhD

Alana L. Reed, PhD

Email: alanaleighreed@gmail.com Phone: 404.547.9027

SUMMARY Independent life sciences professional with proven expertise in the pathology and treatment of human diseases. Strategic and analytical in processing and integrating scientific and clinical information. Areas of scientific expertise include heart failure, hypertension, hypercholesterolemia, pulmonary vascular disease and lymphatic disease. Fast learner who thrives in challenging environments with steep learning curves. Excellent communicator with proven technical writing and presentation skills. Expert mentor and teacher who leads in a collaborative environment.

CORE COMPETENCIES Scientific Expertise: PhD in Biological and Biomedical Sciences in the Molecular and Systems Pharmacology program. Research expertise in cardiovascular, respiratory and lymphatic disease and therapeutic strategies. Ability to analyze and critically evaluate data. Proven record of scientific accomplishment through publication in peer-reviewed journals. Communication: Experience in writing, editing, and reviewing scientific manuscripts and grant proposals. Proficient in designing and delivering presentations at laboratory meetings and journal clubs, local and institutional conferences, and international scientific conventions. Ability to explain complex scientific information to both lay and expert audiences. Clinical Experience: Provided diagnostic laboratory testing for critical care and pulmonary patients. Functioned as part of patient care support team. Understanding of medical terminology and therapeutic strategies. Familiar with healthcare industry and environment, protocols, and regulations. Liaison: Identified and consulted with scientific subject material experts on academic research projects. Organized and directed multidisciplinary collaborative research studies. Experience discussing clinical information with physicians and other healthcare providers.

PROFESSIONAL EXPERIENCE Postdoctoral Research Fellow 2011-2013 Georgia Institute of Technology, Atlanta GA Research focus: Mechanisms of lymphatic lipid transport

§ Designed and carried out research studies which identified mechanisms of lipid transport in the gut, with potential applications toward understanding hypercholesterolemia and developing lipid-based drug formulations.

§ Investigated the role of cancer cell-derived exosome signaling in metastasis via the lymphatic system. § Compiled and presented a review of the role of lipids in lymphatic disease and current therapeutic strategies for

an interdisciplinary conference on lymphedema. § Organized a collaborative study on lymphatic gene expression aimed at elucidating changes in the lymphatic

system in response to hyperlipidemia. § Managed laboratory cell culture operations, including training lab personnel, writing protocols, and performing

necessary troubleshooting and maintenance tasks. § Provided cell culture support and advised laboratory members on the cellular and physiological aspects of their

dissertation projects. § Supervised an undergraduate student under the structured Petit Undergraduate Scholars Program for which the

focus is teaching the student to design an independent research project and critically analyze data and which results in three written research updates and a poster presentation of the research project.

§ Molecular biology and imaging experience includes quantitative real-time PCR, DNA and RNA analysis, immunoblotting, histology and immunohistochemistry, confocal and fluorescence microscopy, ELISA- and fluorescence-based biochemical assays, and near-infrared imaging.

Alana L. Reed, PhD

Graduate Researcher 2004-2011 Emory University, Atlanta GA/Atlanta VA Medical Center, Decatur GA Research focus: Pathophysiology and mechanisms of age-related cardiac dysfunction Awarded funding: NIH T32 Toxicology Training Grant 2004-2006

§ Characterized a mouse model of age-related diastolic heart disease, with implications toward better understanding how age-related heart failure can be detected and reversed.

§ Gained proficiency in small-animal echocardiography and surgical techniques. § Studied the role of oxidative stress in cardiac and pulmonary vascular disease. § Cultured primary mouse cardiac fibroblasts for use in studies aimed at establishing the role of fibrosis in heart

failure. § Co-chaired the Molecular and Systems Pharmacology graduate program recruitment committee, which entailed

planning and organizing interview weekend activities, guiding individual interviewees throughout the recruitment process, and serving as a liaison between interviewees and program faculty.

§ Supervised several SURE (Summer Undergraduate Research at Emory) Program students, for which the goal was an introduction to research, the ability to successfully apply several molecular biology techniques, and the presentation of research findings at a university-wide symposium.

§ Prepared review materials, led study sessions, and provided individual tutoring support as a teaching assistant for the graduate course Principles of Pharmacology.

§ Designed and presented a guest lecture on pulmonary physiology, diseases, and pharmacotherapies to pharmacology graduate students.

Pulmonary Function Laboratory Technician 2003-2004 Emory University Hospital, Atlanta GA

§ Drew and analyzed arterial blood gas samples for pulmonary and critical care patients. § Administered and analyzed pulmonary function tests in the hospital and outpatient clinic. § Developed critical, insightful, and empathic listening skills necessary to explain the details of medical procedures

to patients and families from diverse backgrounds. § Ensured proper documentation of clinical care and represented the laboratory during annual inspections. § Ability to communicate medical information to a wide variety of colleagues, including managers, nurses,

respiratory therapists, and physicians. § Experience with patient confidentiality, standard healthcare procedures, and HIPAA regulatory guidelines.

Undergraduate Researcher 2000-2002 Georgia Institute of Technology, Atlanta GA

§ Performed research as part of the Howard Hughes Medical Institute Undergraduate Research Program. § Conducted field and laboratory work in the area of microbial ecology and genetics. § Developed proficiency in basic microbiology techniques as well as molecular biology techniques such as DNA

cloning and gel electrophoresis. § Acquired and analyzed neurophysiological data using MS Excel and SigmaPlot.

EDUCATION

Ph.D. in Biological and Biomedical Sciences August 2011 Emory University Dissertation: “The Senescence-Accelerated Mouse (SAM): A Murine Model of Age-Associated Diastolic Dysfunction” Program: Molecular and Systems Pharmacology, Toxicology Track B.S. in Applied Biology May 2003 Georgia Institute of Technology Certificate: Industrial and Organizational Psychology

Alana L. Reed, PhD

ACADEMIC AND PROFESSIONAL HONORS

§ Graduate Student Highlights in Respiratory Physiology Poster Session 2006 § NIH T32 Toxicology Training Grant recipient 2004-2006 § Georgia Scholar Award recipient 1999-2003 § National Honor Society Scholarship recipient 1999 § Georgia Tech Club of Augusta Scholarship recipient 1999 § Westinghouse Family Scholarship recipient 1999

RESEARCH ARTICLES

Reed AL, Rowson SA, and Dixon JB. Demonstration of ATP-Dependent, Transcellular Transport of Lipid Across the Lymphatic Endothelium Using an In Vitro Model of the Lacteal. Pharm Res. 2013 Dec;30(12):3271-80. Reed AL, Tanaka A, Sorescu D, Liu H, Jeong EM, Sturdy M, Walp ER, Dudley SC Jr, and Sutliff RL. Diastolic Dysfunction is Associated with Cardiac Fibrosis in the Senescence-Accelerated Mouse. Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H824-31. Xu J, Gonzalez ET, Iyer SS, Mac V, Mora AL, Sutliff RL, Reed A, Brigham KL, Kelly P, and Rojas M. Use of Senescence-Accelerated Mouse Model in Bleomycin-Induced Lung Injury Suggests that Bone Marrow-Derived Cells Can Alter the Outcome of Lung Injury in Aged Mice. J Gerontol A Biol Sci Med Sci. 2009 Jul;64(7):731-9. Nisbet RE, Graves AR, Kleinhenz DJ, Rupnow HL, Reed AL, Fan TM, Mitchell PO, Sutliff RL and Hart CM. The Role of NADPH Oxidase in Chronic Intermittent Hypoxia-Induced Pulmonary Hypertension in Mice. Am J Respir Cell Mol Biol. 2009 May;40(5):601-9.

SCIENTIFIC PRESENTATIONS 16th State of Georgia Lymphedema Education and Awareness Conference, Atlanta GA 2013 Reed AL. Future Directions in Lymphatic Research: Lymphatic Transport of Lipid. Biomedical Engineering Society Annual Meeting, Atlanta GA 2012 Reed AL, Rowson SA, Dixon JB. ATP-Dependent Transport Plays a Pivotal Role in Movement of Lipid Across the Lymphatic Endothelium. American Heart Association Scientific Sessions, Orlando FL 2009 Reed AL, Walp ER, Sutliff RL, and Dudley SC Jr. Diastolic Dysfunction is Associated with Cardiac Fibrosis in the Senescence-Accelerated Mouse. Experimental Biology, San Diego CA 2008 Reed AL, Fan TM, Dudley SC Jr, and Sutliff RL. The Senescence-Accelerated Mouse: A Model for the Investigation of Age-Related Oxidative Stress and Diastolic Dysfunction. Experimental Biology, San Francisco CA 2006 Reed AL, Griendling KK, Elms SC, and Sutliff RL. The Effects of Smooth Muscle-Targeted Nox1-Overexpression in the Development of Hypoxia-Mediated Pulmonary Hypertension.

Alana L. Reed, PhD

COMMUNITY SERVICE AND ACTIVITIES

§ 501(c)(3) Nonprofit Organization Coordinator (2014), Atlanta Rollergirls, Atlanta GA: Responsible for timely documentation of monetary and goods donations. Liaison between the organization and the IRS.

§ Making Strides Against Breast Cancer (2014), American Cancer Association, Atlanta GA: Raised funds and walked as part of an Atlanta Rollergirls-sponsored team to benefit breast cancer awareness and funding.

§ Fight for Air Climb (2013), American Lung Association, Atlanta GA: Raised funds and participated in a race to benefit the American Lung Association.

§ League Statistician (2010-2013), Atlanta Rollergirls, Atlanta GA: Trained and coordinated statistical staff. Analyzed and communicated statistical data to the league as a whole.

§ Labor and Delivery Volunteer (2002), Grady Memorial Hospital, Atlanta GA: Assisted with documentation and paperwork and provided social support to patients and families.

§ Orientation Program Leader (2000-2002), Georgia Institute of Technology, Atlanta GA: Guided incoming freshman, transfer students, and parents through a comprehensive two-day program designed to prepare them for success at Georgia Tech. Advised incoming freshmen about coursework and assisted with course registration.

§ Freshman Council Member (1999-2000), Georgia Institute of Technology, Atlanta GA: Organized a holiday gift drive for underprivileged families. Designed and promoted Tech Beautification Day, a campus-wide volunteer effort to improve the Georgia Tech campus through the planting of flowers and trees. Coordinated an end-of-semester recreational event for the Georgia Tech student body.

§ Avid reader with interests in science journalism, psychology, and American literature. § Other interests include running, swimming, history, and cooking.