7/27/2019 Rare Cancer Presentations_ Intraspinal Metastasis of Lung Cancer _ Center for Oncology Research _ Treatment--D

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MRI images T1 with gadolinium

Figure 2:

Cancer Presentations: Intraspinal Metastasis of Lung Cancer | Center ... http://cancernews.wordpress.com/2009/01/07/rare-cancer-present

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7/27/2019 Rare Cancer Presentations_ Intraspinal Metastasis of Lung Cancer _ Center for Oncology Research _ Treatment--D

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MRI image T2

The patient obtained pain control with narcotic therapy and radiotherapy to the spinal lesion. Hcerebellar metastasis was treated with stereotactic radiosurgery and whole brain radiation. These areawere symptomatically completely controlled (sensory function normalized, no appearance of objectivmotor weakness) and did not progress for 5 months following completion of treatment.

The patient continued with systemic therapy for his cancer, with stable disease in the supraclaviculregion and left lung for 5 months. He sequentially received single-agent docetaxel and single-agengemcitabine. His disease in the supraclavicular area and lung progressed, and he declined furththerapy.

Discussion:

This case illustrates the MRI appearance of an usual intraspinal metastasis of lung cancer involving thfilum terminale. Symptoms of pain, hypoaesthesia below the level of the lesion, lower extremiweakness, and bowel or bladder contractile disturbance may be associated with such disease. Treatmenwith surgical decompresion could be considered for relief of acute neurologic compromise, such paralysis. However, in this case the lesion was treated with radiotherapy, because of the patients pooperformance status, progressive systemic disease at other sites requiring chemotherapy, absence significant motor impairment, and poor predicted short-term prognosis. Radiotherapy was effective fprevention of progressive neural impairment and for pain relief.

Cancer Presentations: Intraspinal Metastasis of Lung Cancer | Center ... http://cancernews.wordpress.com/2009/01/07/rare-cancer-present

8/22/2013

7/27/2019 Rare Cancer Presentations_ Intraspinal Metastasis of Lung Cancer _ Center for Oncology Research _ Treatment--D

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