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![Page 1: Rapid Cycle Evaluation of Improvement Initiatives Gareth Parry, Senior Scientist, IHI Amy Reid, Research Associate, IHI April 11, 2014 1:00 – 2:00pm.](https://reader037.fdocuments.us/reader037/viewer/2022103007/56649cce5503460f949990d5/html5/thumbnails/1.jpg)
Rapid Cycle Evaluation of Improvement InitiativesGareth Parry, Senior Scientist, IHIAmy Reid, Research Associate, IHI
April 11, 20141:00 – 2:00pm
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Conflicts of Interest
Who has paid us to give talks– Nothing to declare
Who has paid us for advice– Nothing to declare
Who has funded our research– Nothing to declare
Who has paid for us to attend conferences– Nothing to declare
Any other interests that could be connected with our work– Nothing to declare
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Introduction1:00 – 1:10
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Agenda
Introduction (10 minutes)
Presentation (30 minutes)
Discussion (15 minutes)
Closing remarks (5 minutes)
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Objectives
Understand the importance of applying rapid-cycle formative evaluation approaches
Describe evaluation designs applicable to improvement projects at the innovation, testing or spread & scale up phases.
Identify and describe realistic aims for your QI projects
Describe the program theory of an improvement project
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Presentation1:10 – 1:40
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Hiraeth
A Welsh word that has no direct English translation.
Homesickness tinged with grief or sadness over the lost or departed, a mix of longing, yearning, nostalgia and wistfulness.– Some concepts can be expressed in a single word in one
language while others require a detailed description. – Some things are just lost in translation
What do we mean by:– Quality Improvement– Evaluation
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Sir Alexander Fleming
Ernst B. Chain Sir Howard Florey
The Nobel Prize for Medicine was awarded in 1945 to:
Penicillin
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Penicillin
1928– From a single petri dish he had discarded, Alexander
Fleming identified a mold and named it Penicillum.
1930s– Fleming tried with limited success to produce and test
the effects of Penicillin as a surface antiseptic.
1939– Ernst Chain took an interest in Fleming’s work and with
Howard Florey identified the active ingredient and produced it in larger quantities.
– Tested it by injecting Penicillin into two infected mice – who recovered.
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Penicillin
1940s– With Norman Heatley, produced sufficient quantities
to test penicillin in fifty mice.– Tested it in three people who were dying from bacterial
infections. – Subsequent successful clinical trials led to funding to
mass produce Penicillin.
1945– Sir Alexander Fleming, Ernst Chain & Sir Howard
Florey awarded Nobel Prize for Medicine
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Sir Henry Harris said at the Florey Centenary lecture in 1998:– "Without Fleming, no Chain; without Chain, no Florey; without
Florey, no Heatley; without Heatley, no penicillin.“
Or:– Without Fleming, no innovation; without Chain and Florey, no
testing, without Heatley, no wide scale use of penicillin
Penicillin
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Degree of belief
ActEvidence
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Degree of Belief in Change Ideas d
egre
e o
f be
lief
Innovation Phase(set design targets, develop
Ideas and predictions, and draftan initial conceptual model and
change package)
Pilot Phase(test and
revise/amend conceptualmodel and
change package)
Adapt and Spread (implement and disseminate
a successful change package)
High
Moderate
Low
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Bayesian Approaches?
Lilford and Braunholtz argue that a theory is needed that links evidence and decision making.
They argue that Bayesian approaches provide the basis of this theory:– “…a decision maker wants to know the probability of an outcome (for example, the
new treatment has lower mortality) given the data…” – A Bayesian approach.
– “… not the probability of the data given an outcome (usually, that there is no difference between treatments).”
– – A conventional Frequentist approach.
Bayesian approaches combine prior ‘degree of belief’ with new data, to calculate an updated ‘degree of belief’ in the form of a posterior probability distribution.
In other words, an existing probability of an outcome in a particular setting can be updated in the light of new data.
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Lilford RJ, Braunholtz D. “Who’s afraid of Thomas Bayes?” 2000; J Epidemiol Community Health
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Perla RJ, Provost LP, Parry GJ. Seven Propositions of the Science of Improvement: Exploring Foundations. Quality Management in Health Care. 2013; 22:170–186
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Aspirational Aims v. Goals• “Aspirational” aims for project motivation need to be
distinguished from realistic goals achievable in the timescale of a project
Example:
Safer Patient Initiative:(5) Benning et al. BMJ 2011: 14% reduction odds of ICU mortality (p=0.250)Study powered to detect a big difference
Keystone:(6) Lipitz-Snyderman et al. BMJ 2011: 11% reduction in odds of ICU mortality (p=0.033)Study powered to detect a smaller but still clinically meaningful difference
(7) Nanji et al. Overarching goals: a strategy for improving healthcare quality and safety? BMJ Qual Saf 2012
(8) Lilford et al. Evaluating policy and service interventions: framework to guide selection and interpretation of study end points. BMJ 2010
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Why Many Improvement Initiatives Are Found to “Fail”
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Peter H. Rossi: The “Iron Law” of Evaluation
“The expected value of any net impact assessment of any social program is zero. This means that our best a priori estimate of a net impact assessment of a program is that it will have no effect.”
Peter H. Rossi (1987) The iron law of evaluation and other metallic rules. Research in Social Problems and Public Policy, 4: 3-20.
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Conclusions: A multipayer medical home pilot, in which participating practices adopted new structural capabilities and received NCQA certification, was associated with limited improvements in quality and was not associated with reductions in utilization of hospital, emergency department, or ambulatory care services or total costs over 3 years. These findings suggest that medical home interventions may need further refinement.
Mark W. Friedberg et al.
February 25, 2014
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Conclusions: Implementation of surgical safety checklists in Ontario, Canada, was not associated with a significant reductions in operative mortality or complications.
David R. Urbach et al.
March 13, 2014
The New England Journal of MedicineIntroduction of Surgical Safety Checklists in Ontario, Canada
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Innovation to Prototyping: Small Number of Settings
Applied in a narrow range of contexts
Improvement in 100% of sites
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Initial Testing:Small Number of Settings
Applied in a wider range of contexts
Improvement in 80% of sites
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More Settings as Range of Contexts Begins to Expand
Applied in a wider range of contexts
Improvement in 70% of sites
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Wide Range of Contexts
Applied in a wide range of
contexts
Improvement in 50% of sites
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Reduction in Effectiveness from Applying the Same Fixed-Protocol Program in Different Contexts
Innovation sample
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Reduction in Effectiveness from Applying the Same Fixed-Protocol Program in Different Contexts
Innovation sample
Evaluation sample
Immediate wide-scale implementation
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Effectiveness May Be Maintained If We Can Learn in What Contexts the Protocol Can Be Amended to Work
Learn which contexts it can be amended to work in as we move from Innovation to Prototype to Test and Spread
Innovation sample
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Donald T. Campbell
“The United States and other modern nations should be ready for an experimental approach to social reform…in which we learn whether or not these programs are effective, and in which we retain, imitate, modify or discard them on the basis of their apparent effectiveness on the multiple imperfect criteria available.”
Donald T. Campbell (1969) Reforms as experiments. American Psychologist, 24(4): 409-29.
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Core Concepts & Detailed Tasks
MEWS >=5Use a reliable method to identify
deteriorating patients in real
time.
When a patient is deteriorating,
provide the most appropriate
assessment and care as soon as
possible
MEWS >=4
2 Nurses1 Physician
1 Nurse1 Physician
1 Physician
ActionTheory
Core Concepts Detailed Tasks and Local
Adaptations
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Core Concepts & Detailed Tasks
Core Concept (Theory)– Describes the underlying principles that underpin a new model
or intervention.
Detailed Tasks (Action)– Describes the detailed actions and activities, associated with a
core concept, that are applied at a local setting.
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What Type of Evaluation?d
egre
e o
f be
lief
Innovation Phase(set design targets, develop
Ideas and predictions, and draftan initial conceptual model and
change package)
Pilot Phase(test and
revise/amend conceptualmodel and
change package)
Adapt and Spread (implement and disseminate
a successful change package)
High
Moderate
Low
FormativeSummative
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1) Generating the pressure (will) for ICUs to take part2) A networked community3) Re-framing BSIs as a social problem4) Approaches that shaped a culture of commitment5) Use of data as a disciplinary force6) Hard edges
Milbank Quarterly 2011
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What are we learning?
The Kirkpatrick Evaluation of Learning Framework has four levels:
1. What was the participants’ experience?– Did the participants have an excellent experience working
on the improvement project?
2. What did the participants learn?– Did they learn improvement methods and begin testing?
3. Did they modify their behavior?– Did they work differently and see change in their process
measures?
4. Did the organization improve their performance?– Did they improve their outcomes?
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Content Theory
WHAT CHANGES WILL TEAMS MAKE THAT WILL RESULT IN IMPROVEMENT?
Explains how we predict that the change concepts and improvement drivers applied in the project will lead to improved outcomes.
Change Concepts, Improvement Drivers
LEVEL 3
Organizational, Patient-level Outcomes
LEVEL 4
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Execution Theory
WHAT WILL YOU DO THAT WILL LEAD TEAMS TO ADOPT THE PROCESS CHANGES?
Explains what IHI and other partners are doing that will lead front-line teams to adopt the changes (improvement drivers) described in the content theory.
IHI Activities
External Partner Activities
Participant Experience
Level 1
Learning
Level 2
Process/Behavior Changes
Level 3
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Across Relevant Kirkpatrick Levels
What was the aspiration goal?
What would be considered a success?
Results over time.
What enabled or became a barrier for improvement?
What worked for whom over what time period?
Conceptual Model
What’s the theory?
New Conceptual
ModelWhat’s the new
theory?
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An Approach to Evaluation
Assumptions from a Science of Improvement Perspective:– Learn what is takes to bring about improvement.
– Improvement requires social change and that people are more likely to act if they believe.
– Interventions need to be amended to local settings (contexts).
– Concepts rather than fixed protocols are a good starting point for people to test and learn whether improvement interventions can be amended to their setting.
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Discussion1:40 – 1:55pm
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With the person next to you…
What are your initial thoughts about this type of approach?
How would you implement this approach?
What major challenges would you foresee?
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Closing Remarks1:55 – 2:00 pm
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Outcomes Improved?
Test and Refine
Site Implementation
Conceptual Model
Local Experience
Broad Concepts
Prior Research
and Experience
A. Contextual Adaptation
B. Contextual Adaptation
C. Contextual Adaptation
Etc.
Generalizable Knowledge
Amendment 1Amendment 2Amendment 3Amendment 4
Yes
No
Yes
Generalizable Specific to Context
Ovretveit, Leviton, Parry, BMJ Qual Saf 2011
Amendment 1Amendment 2Amendment 3Amendment 4
Amendment 1Amendment 2Amendment 3Amendment 4
=
=
=
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Perla RJ, Provost LP, Parry GJ. Seven Propositions of the Science of Improvement: Exploring Foundations. Quality Management in Health Care. 2013; 22:170–186
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An Approach to Improvement
Assumptions from a Science of Improvement Perspective:– Learn what is takes to bring about improvement.
– Interventions need to be amended to local settings (contexts).
– Concepts rather than fixed protocols are a good starting point for people to test and learn whether improvement interventions can be amended to their setting.
– Provide a prediction, or degree of belief a model will achieve a particular impact in a specific setting.
– Improvement requires social change and that people are more likely to act if they believe.
Epistemology
Psychology
Variation
Systems
The “Science of Improvement “ is an applied science, with philosophical
underpinnings.
It is not a specific intervention.