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CONTENT

01 About Nipro Glass

02 Our Products

03 Technical Information

HistoryVertical IntegrationPartnershipOur Goal

TubingVialsAmpoulesCartridgesSyringesSterile Products

1.11.21.31.4

2.12.22.32.42.52.6

ABOUT NIPRO GLASS01.

Years of history in pharmaceutical market

60

In July 1954, Nippon Glass Shoji Co. was established in

Shimogyo-Ku of Kyoto city and initiated sales

of glass tubes for use in the production of

ampoules and pharmaceutical vials.

Almost 60 years after its establishment,

Nipro embarked on a journey to become a

major world class glass producer/supplier,

setting out to make a strong presence in the

glass packaging industry.

In 2011,

Nipro acquired Amcor Glass, with factories

located in France, Belgium and the United

States of America, now respectively Nipro

Glass France, Nipro Glass Belgium and Nipro

Glass Americas.

Further expansion continued with a

a re-organized Tube Drawing facility in India.

In 2012, Nipro acquired MGlass AG and MG Sterile

Products AG, now Nipro Glass Germany and

Nipro Sterile Glass Germany.

With a proud 60 year history of pharmaceutical market service, Nipro Glass provides unparalleled industry knowledge and expertise to its customers.

Furthermore, our focus on invest-ments and responsive account management allows Nipro Glass to better partner with our customers to help meet and exceed their business goals.

Nipro Glass (Americas)Millville

WestportChase City

Sales team factories

Tubing and converting

Converting

Sterile product

VERTICAL INTEGRATIONWith worldwide glass manufacturing and converting facilities located in Europe (France, Germany, Belgium), the US (Millville, Chase City, Westport), India, Indonesia, Japan, China and Russia, Nipro Glass is a vertically integrated global supplier of pharmaceutical tubular glass packaging, positioned to meet global demand and to provide continuity of supply to our customers.

Our glass product range extends from tubing, vials, ampoules, cartridges to sterile syringes and vials under the trade mark D2F® (Direct-To-Fill).

Meerut

Chengdu

Authon du PercheAumale

Nipro Glass (Russia)

Nipro Glass (China)

Nipro Glass (Europe)

Nipro Glass (India)

Nipro Glass (Indonesia)

Nipro Corporation (Japan)

Lucenay des Aix

Grace au Hollogne

MünnerstadtMünnerstadt

Agartala

Anyang

OtsuJilin

KhopoliChiplun

Panvel

Karawan

Badlapur

PARTNERSHIPIn each business area of Nipro Corporation, we are focused on building a long-term partnership with each customer. From the silica sand used to make the glass, to the

promise of serving and enhancing patient care. Every Nipro employee understands this credo and is held accountable to deliver on this promise. World-class processes and controls ensure that our customers’ expectations are met. Our commitment is to work with our customers and to contribute to the greater mission.

OUR GOAL IS ZERO-DEFECT QUALITY LEVELS

our glass products are designed and manufactured to the highest quality standards. World-class processes and controls ensure quality. We make billions of vials and ampoules on a daily basis knowing that each one can make a difference.

Continuous Improvement Program

The Nipro Quality Management System began

with establishing a quality mindset.

Our management team and our employees are

committed to quality and we provide our

employees with continuous training through

progressive education. Within the Nipro Group,

Continuous Improvement aims at maximizing

opportunities and making optimal use of existing

and competitiveness.

Nipro‘s Japanese quality standards combined

with our in-line camera inspection system and

360° visual inspection and clean rooms class 8

not only allows us to deliver a superior product

to our customers, but also provides means to

capture and quantify our internal capabilities, so

that we can continuously improve our processes.

Best practice sharing is encouraged and

utilized across our sites, all our sites are

• ISO 15378• • ISO 14001• OHSAS 18001

In-House Technology

• Fully automated machines• In-line camera inspection• Highest precision during

forming process• 100% vision inspection

More than 30 years of experience in building

forming machines allows us to better respond

to your needs and to design a forming machine

that meets your expectations. Our expert teams

listen to your needs and use their skills,

versatility and expertise to meet your production

and account management needs.

OUR PRODUCTS02.

TUBING

HIGH QUALITY GLASS TUBING FOR PHARMACEUTICAL PACKAGING

With state-of-the-art Danner and Vello drawing processes, our range of glass is particularly suited for vials, cartridges, injectable or drinking ampoules,

Properties include excellent mechanical strength and thermal properties with maximum workability in customer transformation processes.

Quality control spans all of our processes from the batch house, where raw materials are received and mixed; to the melting and forming processes; to

Manufacturing lines are equipped with in-line vision inspection systems that inspect every glass tube. Moreover, manual inspection comes as a back-up, in order to ensure that all quality parameters are met, both dimensional and cosmetic.

the current United States, European and Japanese Pharmacopeia (USP, EP and JP).

W33 Type I Clear Borosilicate Glass

- Low expansion neutral formulation- High chemical durability- Enhanced resistance to thermal shock- Manufactured in Millville (USA)

NSV51Type I Clear Borosilicate Glass

- Neutral formulation- Can also be manufactured with Cerium for gamma sterilization- Manufactured in Aumale (FR) and Millville (USA)

WG6Type III Clear Soda Lime Glass

- Can also be manufactured with Cerium for gamma sterilization- Manufactured in Millville (USA)

G38 Type III Half Neutral Borosilicate Glass

- Half-neutral yellow colored glass- UV resistant - Very stable to heat treatment and mechanical strength- Manufactured in Aumale (FR)

NA54 Type I Amber Borocilicate Glass

- Amber colored glass which offers UV resistant properties - Well suited for injectable application- Manufactured in Aumale (FR)

VIALS

GLASS VIALS FOR PHARMACEUTICAL USE

Nipro Glass offers a standard product line of vials from 2ml to 50ml in different designs. These models have passed the test of time and are produced with consistency at our vial converting sites.

According to industry standard or to your individual

are able to build the perfect vial for your needs

requirement.

• Type I Clear glass • Type I Amber glass• Better shape consistency• Stronger thermal shock resistance• Reduced contact with forming tools

give a superior cosmetic appearance

Pharmaceutical vials

• Injection/ Infusion Vials• Screw Neck Vials• Large volume vials

Special vials

• Unit dose vial• Bi-dose vial• ProDose vial• V-bottom vial• High recovery vial• Double chamber vial• Clean vial

Features

Several features can be addedto your Standard or Custom Design vial.

• • 100% vision and manual inspection• Blowback (Type I or II)• Various level of packaging (Cell Pack available)

AMPOULES

PRIMARY PACKAGING GLASS AMPOULES

Glass ampoules are the ideal packaging material

tamper-proof, transparent, durable, impermeable to gas and resistant to any interaction between container and content. Total product safety is guaranteed through these essential properties.

Our standard range of ampoules offer you a wide variety of high-quality products. The quality of these products is monitored at every stage of the production process by on-line camera inspection for dimensional and visual criteria.

• Type I Clear glass• Type I Amber glass • Filling capacities from 1ml to 25ml• Fine tip, Double tip, Straight-stem,

Open funnel and Closed-stem ampoules• Various break systems such as OPC (One Point

Cut), CBR (Colour Break Ring) and SCR (Score Ring)

• Customized printing• Drug Master File Type III

Quality

• In-process control by statistical sampling• Physical and chemical analysis according to

US, EU and JP Pharmacopoeias• Class 100 000 packaging rooms

CARTRIDGES

GLASS CARTRIDGES FOR DRUG DELIVERY SYSTEMS

Nipro Glass cartridges are produced to meet the highest quality requirement of the pharmaceutical industry.Our standard cartridges range from 1.8ml

packaging equipment, injection systems like dental anesthetics, as well as other applications.

Our high quality lines use visual inspection systems for 100% dimensional control and cosmetic defects. Final packaging is performed under controlled environmental conditions.

• Type I Clear glass • Customized ceramic printing• Drug Master File Type III• Sizes from 1.8ml to 3.0ml, larger sizes on

request

SYRINGES

WIDE RANGE OF PREFILLABLE GLASS SYRINGE SYSTEMS

systems both as bulk products and in a ready-to-use format. These syringes under our trademark D2F® (Direct-To-Fill) are washed, siliconized and sterilized (ETO).System accessories complete the range and make our syringes deliverable as complete sets according to customer requirements.

• Type I Clear glass• Compliance with USP, EP, JP•

equipment• Customized ceramic printing• Sizes from 0.5ml to 10.0ml• Drug Master File Type III

Components

• Closure solutions for Luer-Lock cone, Luer-Slip cone and Bonded Needle

• Plunger stoppers and rods in different rubber formulations

Besides Glass Syringes, Nipro also offers a wide range of plastic syringes and needles. Further information on request.

STERILE SOLUTIONS

D2F® DIRECT-TO-FILL

Nipro Sterile Glass products D2F® (Direct-To-Fill) are manufactured by washing, drying, siliconization and closure assembly on fully-automated, state-of-the-art washing and packaging lines. Validated washing and siliconization processes ensure the highest quality standards.

Our D2F® syringes and vials are delivered pre-packed in a sterile packaging which is available in all common nest, tub and breather bag or tray, lid/front wall and breather bag.

• Pre-packed sterile packaging for immediate

• Drug Master File Type III, available with FDA (USA) and HPFB (Canada)

• Type I Clear glass• Compliance with USP, EP, JP• D2F® process steps: washing,

siliconization, assembly, packaging• 360° visual inspection• Clean room according to pharmaceutical

requirements• Fully automated lines including packaging

D2FDirect To Fill

TEST TUBES

COLLECTION TUBES FOR LABORATORY EXPERIMENTS AND CHEMICAL ANALYSES

Nipro Glass test tubes are ideal for simple experiments, in particular for chemical analyses.

Our test tubes are manufactured from Type I borocilicate glass for a better resistance to heat, corrosive chemicals and a longer life.

High quality and performance in laboratorium is ensured by our state-of-the-art production lines.

• Type I Clear glass• Available in different sizes

NOTES

EUROPENIPRO GLASS EUROPEWeihoek 3H1930 ZaventemBelgiumT: +32 (0)2 725 55 33info@niproglass.comwww.niproglass.com

United States of AmericaNIPRO GLASS AMERICAS1200 North 10th StreetMillville, NJ 08332T: +1 (0)856 825 1400info@niproglassamericas.comwww.niproglass.com

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