Pulmonary Lab. HPI 24 yo male pt w/ CF presents to ER with 4 day hx of fevers, chills, hemoptysis,...
-
Upload
ashlynn-miller -
Category
Documents
-
view
215 -
download
0
Transcript of Pulmonary Lab. HPI 24 yo male pt w/ CF presents to ER with 4 day hx of fevers, chills, hemoptysis,...
Pulmonary Lab
HPI
• 24 yo male pt w/ CF presents to ER with 4 day hx of fevers, chills, hemoptysis, and thick purulent sputum production
• He has failed outpatient abx therapy
• Pt has been hospitalized 4x in the last year for recurrent PNAs
PMH/PSH
• Recurrent PNAs• Pancreatic insufficiency (malabsorption)• GERD
• G-tube• Rt sided port
Social Hx
• Pt is non-compliant with home meds
Results of Testing
• Sputum cultures– Multidrug resistant pseudomonas aeruginosa– MSSA– Acinetobacter
Chest Xray• This diagram is a Chest
Radiograph of Cystic Fibrosis (CF) Diffuse Interstitial Disease. This frontal chest X ray in CF shows diffuse interstitial disease with bronchiectasis and nodular densities of mucoid impaction.
Chest CT
• Multicystic space within the base of the left lower lobe which is continuous with the small airways and is representative of cystic bronchiectasis.
Hospital Course
• Pt progresses to respiratory failure• Placed on ventilator• Becomes septic• Unable to wean from vent• Pt expires from sepsis and respiratory failure
Gross Specimen CF Lungs
Bronchiectasis
H&E Low Power Lung, CF
• 1.5x
H&E High Power CF, Lung
• Section of a dilated bronchi with florid acute on chronic inflammation of the bronchial wall and surrounding interstitial fibrosis.
5xBronchiectasis
Treatments for CF, Lung
• Broad spectrum abx• Duonebs• PFTs• Chest physiotherapy – helps pt expectorate sputum• Bronchodilators• Dornase alpha – cleaves DNA, decreases viscosity• Inhaled hypertonic saline – hydrates lung secretions• Anti-inflammatories • Lung Tansplant