Publication List - 1939-1966 (Arranged Chronologically by Year)

From “The Clayton Foundation Biochemical Institute – A Short History” – by Roger J. Williams Edited by Donald R. Davis and Marvin L. Hackert,. 2001

1. Snell, E. E., and R. J. Williams, Biotin as a Growth Factor for the Butyl Alcohol Producing

Anaerobes, J. Am. Chem. Soc., 61, 3594 (1939). 2. Snell, E. E., R. E. Eakin, and R. J. Williams, A Quantitative Test for Biotin and Observations

Regarding Its Occurrence and Properties, J. Am. Chem. Soc., 62, 175–8 (1940). 3. Williams, R. J., and R. T. Major, The Structure of Pantothenic Acid, Science, 91, 246 (1940). 4. Eakin, R. E., W. A. McKinley, and R. J. Williams, Egg-White Injury in Chicks and Its

Relationship to a Deficiency of Vitamin H (Biotin), Science, 92, 224–5 (1940). 5. Mitchell, H. K., H. H. Weinstock, E. E. Snell, S. R. Stanbery, and R. J. Williams, Pantothenic

Acid. V. Evidence for Structure of Non-beta-Alanine Portion, J. Am. Chem. Soc., 62, 1776–9 (1940).

6. Zschiesche, E., and H. K. Mitchell, Pantothenic and Hydroxypantothenic Acids in Animal Nutrition, Proc. Soc. Expt. Biol. Med., 45, 565 (1940).

7. Stanberry, S. R., E. E. Snell, and T. D. Spies. A Note on an Assay Method for Pantothenic Acid in Human Blood, J. Biol. Chem., 135, 353 (1940).

8. Williams, R. J., H. K. Mitchell, H. H. Weinstock, and E. E. Snell, Pantothenic Acid. VII. Partial and Total Synthesis Studies, J. Am. Chem. Soc., 62, 1784–5 (1940).

9. Mitchell, H. K., E. E. Snell, and R. J. Williams, Pantothenic Acid. IX. The Biological Activity of Hydroxypantothenic Acid, J. Am. Chem. Soc., 62, 1791–2 (1940).

10. Williams, R. J., Vitamin Study at The University of Texas, Science, 92, 579 (1940). 11. Pennington, D., E. E. Snell, and R. J. Williams, An Assay Method for Pantothenic Acid, J.

Biol. Chem., 135, 213–22 (1940). 12. Snell, E. E., D. E. Pennington, and R. J. Williams, The Effect of Diet on the Pantothenic

Acid Content of Chick Tissue, J. Biol. Chem., 133, 559–65 (1940). 13. Spies, T. D., S. R. Stanberry, R. J. Williams, T. H. Jukes, and S. H. Babcock, Pantothenic

Acid in Human Nutrition, J. Am. Med. Assoc., 115, 523–4 (1940). 14. Williams, R. J., R. E. Eakin, E. E. Snell, The Relationship of Inositol, Thiamin, Biotin,

Pantothenic Acid and Vitamin B6 to the Growth of Yeasts, J. Am. Chem. Soc., 62, 1204–7 (1940).

15. Eakin, R. E., E. E. Snell, and R. J. Williams, A Constituent of Raw Egg White Capable of Inactivating Biotin in Vitro, J. Biol. Chem., 136, 801–2 (1940).

16. Mitchell, H. K., and R. J. Williams, The Importance of Amino-Acids as Yeast Nutrients, Biochem. J., 34, 1532–5 (1940).

17. Williams, R. J., Growth-Promoting Nutrilites for Yeasts, Biol. Rev., 16, 49–80 (1941). 18. Williams, R. J., The Importance of Microorganisms in Vitamin Research, Science, 93, 412–4

(1941). 19. Eakin, R. E., E. E. Snell, and R. J. Williams, The Concentration and Assay of Avidin, The

Injury-Producing Protein in Raw Egg White, J. Biol. Chem., 140, 535–43 (1941). 20. Gyorgy, P., C. S. Rose, R. E. Eakin, E. E. Snell, and R. J. Williams, Egg-White Injury as the

Result of Nonabsorption or Inactivation of Biotin, Science, 93, 477–8 (1941). 21. Mitchell, H. K., E. E. Snell, and R. J. Williams, The Concentration of “Folic Acid”, J. Am.

Chem. Soc., 63, 2284 (1941). 22. Williams, R. J., Pantothenic Acid, Enzymologia, IX, 387–94 (1941).

23. Williams, R. J., Pantothen, Science, 94, 462–3 (1941). 24. Snell, E. E., and L. D. Wright, A Microbiological Method for the Determination of Nicotinic

Acid, J. Biol. Chem., 139, 675 (1941). 25. Snell, E. E., Growth Inhibition by N-(α,γ-Dihydroxy-β,β-dimethylbutyryl)taurine and Its

Reversal by Pantothenic Acid, J. Biol. Chem., 141, 121 (1941). 26. Snell, E. E., and E. Quarles, The Effect of Incubation on the Vitamin Content of Hen Eggs, J.

Nutr., 22, 483 (1941). 27. Taylor, A., J. Thacker, and D. E. Pennington, The Effect of Increased Pantothenic Acid in the

Egg on the Development of the Chick Embryo, Science, 94, 542 (1941). Biochemical Institute Studies I—Studies on the Vitamin Content of Tissues I, Univ. Texas Publ.,

4137, (1941).

28. Williams, R. J., Introduction, 7–9. 29. Snell, E. E., and F. M. Strong, Assay Method for Riboflavin, 11–13. 30. Pennington, D. E., E. E. Snell, H. K. Mitchell, J. R. McMahan, and R. J. Williams, Assay

Method for Pantothenic Acid, 14–17. 31. Snell, E. E., R. E. Eakin, and R. J. Williams, Assay Method for Biotin, 18–21. 32. Snell, E. E., and L. D. Wright, Assay Method for Nicotinic Acid, 22–23. 33. Williams, R. J., R. E. Eakin, and J. R. McMahan, Assay Method for Pyridoxin, 24–6. 34. William, R. J., A. K. Stout, H. K. Mitchell, and J. R. Mitchell, and J. R. McMahan, Assay

Method for Inositol, 27–30. 35. Williams, R. J., J. R. McMahan, and R. E. Eakin, Assay Method for Thiamin, 31–5. 36. Mitchell, H. K., and E. E. Snell, Assay Method for “Folic Acid”, 36–37. 37. Wright, L. D., J. R. McMahan, V. H. Cheldelin, A. Taylor, E. E. Snell, and R. J. Williams,

The “B Vitamins” in Normal Tissues (Autolysates), 38–60. 38. Williams, R. J., A. Taylor, and V. H. Cheldelin, Changes in “B Vitamin” Content of Tissues

During Development, 61–66. 39. Taylor, A., H. K. Mitchell, and M. A. Pollack, Modification of “B Vitamin” Content During

Embryological Development, 67–80. 40. Thompson, R. C., R. E. Eakin, and R. J. Williams, The Extraction of Biotin from Tissues,

Science, 94, 589–90 (1941). 41. Snell, E. E., and H. K. Mitchell, Purines and Pyrimidine Bases as Growth Substances for

Lactic Acid Bacteria, Proc. Natl. Acad. Sci., 27, 1 (1941). 42. Snell, E. E., E. Aline, J. R. Couch, and P. B. Pearson, The Effect of Diet on the Pantothenic

Acid Content of Eggs, J. Nutr., 21, 201 (1941). 43. Snell, E. E., A Specific Growth Inhibition Reversed by Pantothenic Acid, J. Biol. Chem.,

139, 975 (1941). 44. Williams, R. J., An Introduction to Organic Chemistry, (Book) 1927, 2nd ed. 1931, 3rd ed.

1935, 4th ed. 1941, 5th ed. (with L. F. Hatch) 1948, D. Van Nostrand Co., Inc., New York. 45. Pennington, D. E., E. E. Snell, and R. E. Eakin, Crystalline Avidin, J. Am. Chem. Soc., 64,

469 (1942). 46. Taylor, A., and M. A. Pollack, Hemoglobin Level and Tumor Growth, Cancer Res., 2, 223

(1942). 47. Pollack, M. A., and M. Lindner, Glutamine and Glutamic Acid as Growth Factors for Lactic

Acid Bacteria, J. Biol. Chem., 143, 272 (1942).

49. Eakin, R. E., and E. A. Eakin, A Biosynthesis of Biotin, Science, 96, 187 (1942). 50. Snell, E. E., and H. K. Mitchell, Some Sulfanilamide Antagonists as Growth Factors for

Lactic Acid Bacteria, Arch. Biochem., 1, 93 (1942). 51. Taylor, A., J. Thacker, and D. E. Pennington, Growth of Cancer Tissue in the Yolk Sac of the

Chick Embryo, Science, 96, 342 (1942). 52. Pollack, M. A., A. Taylor, and C. L. Sortomme, The Effect of Variations in Oxygen Pressure

Upon Tumor Transplants, Cancer Res., 2, 828 (1942). 53. Snell, E. E., Effect of Heat Sterilization on Growth-Promoting Activity of Pyridoxine for

Streptococcus lactis R., Proc. Soc. Exptl. Biol. Med., 51, 356 (1942). 54. Williams, R. J., Vitamins in the Future, Science, 95, 340–44 (1942). 55. Snell, E. E., B. M. Guirard, and R. J. Williams, Occurrence in National Products of a

Physiologically Active Metabolite of Pyridoxine, J. Biol. Chem., 143, 519–30 (1942). 56. Williams, R. J., The Approximate Vitamin Requirements of Human Beings, J. Am. Med.

Assoc., 119, 1–7 (1942). 57. Teague, P. C., and R. J. Williams, Pantothenic Acid and the Utilization of Glucose by Living

and Cell-Free Systems, J. Gen. Physiol., 25, 777–83 (1942). 58. Cheldelin, V. H., and R. J. Williams, Adsorption of Organic Compounds. I. Adsorption of

Ampholytes on an Activated Charcoal, J. Am. Chem. Soc., 64, 1513–6 (1942). 59. Williams, R. J., Pantothenic Acid and the Microbiological Approach to the Study of

Vitamins, The Biological Action of the Vitamins (E. A. Evans, ed.), Univ. Chicago Press, 120–35 (1942).

Biochemical Institute Studies II—Studies on the Vitamin Content of Tissues II, Univ. Texas.

Publ. 4237, (1942).

60. Williams, R. J., Introduction—Microbiological Assay Methods, 7–14. 61. Cheldelin, V. H., M. A. Eppright, E. E. Snell, and B. M. Guirard, Enzymatic Liberation of B

Vitamins from Plant and Animal Tissues, 15–36. 62. Mitchell, H. K., and E. R. Isbell, B Vitamin Content of Normal Rat Tissues, 37–40. 63. Taylor, A., M. A. Pollack, and R. J. Williams, B Vitamins in Normal Human Tissues, 41–55. 64. Pollack, M. A., A. Taylor, and R. J. Williams, B Vitamins in Human, Rat and Mouse

Neoplasms, 56–71. 65. Taylor, A., M. A. Pollack, and C. L. Sortomme, Effect of B Vitamins in the Diet on Tumor

Transplants, 72–80. 66. Isbell, E. R., H. K. Mitchell, A. Taylor, and R. J. Williams, A Preliminary Study of B

Vitamins in Cell Nuclei, 81–3. 67. Woods, A. M., J. Taylor, M. J. Hofer, G. A. Johnson, R. L. Lane, and J. R. McMahan, The B

Vitamin Content of Organisms of Different Biological Phyla, 84–86. 68. Thompson, R. C., Synthesis of B Vitamins by Bacteria in Pure Culture, 87–96. 69. Williams, R. J., V. H. Cheldelin, and H. K. Mitchell, The B Vitamin Content of Milk from

Animals of Different Species, 97–104. 70. Cheldelin, V. H., and R. J. Williams, The B Vitamin Content of Foods, 105–24. 71. Mitchell, H. K., and E. R. Isbell, Intestinal Bacterial Synthesis as a Source of B Vitamins for

the Rat, 125–34. 72. Taylor, A., D. E. Pennington, and J. Thacker, The Vitamin Requirements of Cecectomized

Rats, 135–44. 73. Mitchell, H. K., A Simple Microgrinder for Tissues, 145.

74. Pollack, M. A., A. Taylor, J. Taylor, and R. J. Williams, B Vitamins in Cancerous Tissues. I.

Riboflavin, Cancer Res., 2, 739–43 (1942). 75. Taylor, A., M. A. Pollack, M. J. Hofer, and R. J. Williams, B Vitamins in Cancerous Tissues.

II, Nicotinic Acid, Cancer Res., 2, 744–7 (1942). 76. Pollack, M. A., A. Taylor, A. Woods, R. C. Thompson, and R. J. Williams, B Vitamins in

Cancerous Tissues. III. Biotin, Cancer Res., 2, 748–51 (1942). 77. Taylor, A., M. A. Pollack, M. J. Hofer, and R. J. Williams, B Vitamins in Cancerous Tissues.

IV. Pantothenic Acid, Cancer Res., 2, 752 (1942). 78. Taylor, M. A. Pollack, and R. J. Williams, Uniformities in the Content of B Vitamins in

Malignant Neoplasms, Science, 96, 322–3 (1942). 79. Williams, R. J., A Textbook of Biochemistry (Book) 1938, 2nd ed. 1942, D. Van Nostrand

Co., Inc., New York. 80. Taylor, A., The Successful Production of a Mammalian Tumor with a Virus-Like Principle,

Science, 97, 123 (1943). 81. Snell, E. E., L. Chan, S. Spiridanoff, E. L. Way, and C. D. Leake, Production of Pantothenic

Acid Deficiency in Mice with Pantoyltaurine, Science, 97, 168 (1943). 82. Mitchell, H. K., E. R. Isbell, and R. C. Thompson, Microbiological Assays for p-

Aminobenzoic Acid, J. Biol. Chem., 147, 485 (1943). 83. Snell, E. E., and B. M. Guirard, Some Interrelationships of Pyridoxine, Alanine and Glycine

in Their Effect on Certain Lactic Acid Bacteria, Proc. Natl. Acad. Sci., 92, 66 (1943). 84. Williams, R. J., The Significance of the Vitamin Content of Tissues, Vitamins and

Hormones, (R. S. Harris and K. Thimann, ed.), Academic Press, N. Y., 229–47 (1943). 85. Williams, R. J., Water-Soluble Vitamins, Annual Review of Biochemistry (J. M. Luck, ed.),

Stanford Univ. Press, XII, 305–52 (1943). 86. Williams, R. J., The Chemistry and Biochemistry of Pantothenic Acid, Advances in

Enzymology (F. F. Nord and C. H. Werkman, ed.), Interscience Publishers, N. Y., 253–87 (1943).

87. Williams, R. J., Isotel, Isotelic, Science, 98, 386 (1943). 88. Cheldelin, V. H., A. M. Woods, and R. J. Williams, Losses of B Vitamins Due to Cooking of

Foods, J. Nutr., 26, 477–85 (1943). 89. Taylor, A., D. E. Pennington, and J. Thacker, The Effect of High Levels of Pantothenic Acid

on Reproduction in the Rat and the Mouse, J. Nutr., 25, 389 (1943). 90. Pollack, M. A., The Absence of beta-Alanine in Proteins, J. Am. Chem. Soc., 65, 484 (1943). 91. Mitchell, H. K., Biological Specificity of Folic Acid, Science, 97, 442 (1943). 92. Thompson, R. C., E. R. Isbell, and H. K. Mitchell, A Microbiological Assay Method for p-

Aminobenzoic Acid, J. Biol. Chem., 148, 281–7 (1943). 93. Pollack, M. A., Growth Effects of alpha-Methyl Homologs of Pantothenic Acid and beta-

Alanine, J. Am. Chem. Soc., 65, 1335 (1943). 94. Thompson, R. C., The B Vitamin Requirements of the Propionibacteria, J. Bact., 46, (1943). 95. Taylor, A., The Problem of the Etiology of the Cancer Process, Southern Med. and Surgery,

104, 291 (1943). 96. Taylor, A., R. E. Hungate, and D. R. Taylor, Yolk Sac Cultivation of Tumors, Cancer Res.,

3, 537 (1943). 97. Taylor, D. R., M. McAfee, and A. Taylor, The Effect of Yolk Sac-Cultivated Tumors on the

Hemoglobin Level in the Embryonic Chick, Cancer Res., 3, 542 (1943).

98. Snell, E. E., Growth Promotion on Tryptophan-Deficient Media by o-Aminobenzoic Acid and Its Attempted Reversal with Orthanilamide, Arch. Biochem., 2, 389 (1943).

99. Cheldelin, V. H., and R. L. Lane, B Vitamins in Germinating Seeds, Proc. Soc. Exptl. Biol. Med., 54, 53 (1943).

100. Pollack, M. A., and M. Linder, A Growth Stimulant for Lactobacillus casei, J. Biol. Chem., 147, 183 (1943).

101. Lankford, C. E., and E. E. Snell, Glutamine as a Growth Factor for Certain Strains of Neisseria gonorrhoeae, J. Bact., 45, 410 (1943).

102. Mitchell, H. K., and R. J. Williams, Folic Acid. III. Chemical and Physiological Properties, J. Am. Chem. Soc., 66, 271–4 (1944).

104. Williams, R. J., F. Schlenk, and M. A. Eppright, The Assay of Purified Proteins, Enzymes, Etc., for “B Vitamins,” J. Am. Chem. Soc., 66, 896–8 (1944).

105. Chu, E. J. H., and R. J. Williams, A Reported Growth Stimulant for Lactobacillus casei, J. Biol. Chem., 155, 9–11 (1944).

106. Eppright, M. A., and R. J. Williams, Thiamine Determination—Comparative Study of Yeast Growth, Yeast Fermentation and Thiochrome Methods, Ind. Eng. Chem., Anal. Ed., 16, 576–9 (1944).

107. Chu, E. J. H., and R. J. Williams, The Question of the Existence and Significance of Avidin-Uncombinable Biotin Isotels, J. Am. Chem. Soc., 66, 1678–80 (1944).

108. Williams, R. J., M. A. Eppright, E. Cunningham, and C. A. Mills, B Vitamins in the Tissues of Rats Maintained at High and Low Temperatures, Arch. Biochem., 5, 299–306 (1944).

109. Williams, R. J., B Vitamins and Cancer, Proc. Am. Assoc. Adv. Sci. Research Conf., 253–66 (1944).

110. McMahan, J. R., and E. E. Snell, The Microbiological Determination of Amino Acids, I. Valine and Arginine, J. Biol. Chem., 152, 83 (1944).

111. Snell, E. E., Effect of Alanine on Response of Lactobacillus casei to Pyridoxine and Folic Acid, Proc. Exptl. Biol. Med., 55, 36 (1944).

112. Snell, E. E., The Effect of Polyamines on Bacteriostasis by 4,4´-Diamidinodiphenoxypropane, J. Biol. Chem., 152, 475 (1944).

113. Mitchell, H. K., Folic Acid, IV. Absorption Spectra, J. Am. Chem. Soc., 66, 274 (1944). 114. Hungate, R. E., A. Taylor, and R. C. Thompson, The Relations to Chick Tissues of Tumors

Produced by the Yolk Injection Technic, Cancer Res., 4, 289 (1944). 115. Snell, E. E., The Vitamin Activities of “Pyridoxal” and “Pyridoxamine,” J. Biol. Chem.,

154, 313 (1944). 116. Thompson, M. L., E. Cunningham, and E. E. Snell, The Nutritive Value of Canned Foods.

IV. Riboflavin and Pantothenic Acid, J. Nutrition, 28, 123 (1944). 117. Snell, E. E., The Vitamin B6 Group. I. Formation of Additional Members from Pyridoxine

and Evidence Concerning their Structure, J. Am. Chem. Soc., 66, 2032 (1944). 118. Taylor, A., and A. Kynette, The Virus Production of Mammalian Tumors, Am. Assoc. Adv.

Sci. Research Conf. on Cancer (1944). 119. Mitchell, H. K., E. E. Snell, and R. J. Williams, Folic Acid. I. Concentration from Spinach,

J. Am. Chem. Soc., 66, 269–71 (1944). 120. Frieden, E. H., H. K. Mitchell, and R. J. Williams, Folic Acid. II. Studies on Adsorption, J.

Am. Chem. Soc., 66, 269–71 (1944). 121. Snell, E. E., and A. N. Rannefeld, The Vitamin Be Group. III. The Vitamin Activity of

Pyridoxal and Pyridoxamine for various Organisms, J. Biol. Chem., 157, 475–89 (1945).

122. Snell, E. E., The Vitamin B6 Group. IV. Evidence for the Occurrence of Pyridoxamine and Pyridoxal in Natural Products, J. Biol. Chem., 157, 491 (1945).

123. Schlenk, F., and E. E. Snell, Vitamin B6 and Transamination, J. Biol. Chem., 157, 425 (1945).

124. Snell, E. E., The Vitamin B6 Group. V. The Reversible Interconversion of Pyridoxal and Pyridoxamine by Transamination Reactions, J. Am. Chem. Soc., 67, 194 (1945).

125. Snell, E. E. and W. Shive, Growth Inhibition by Analogues of Pantothenic Acid. Pantothenyl Alcohol and Related Compounds, J. Biol. Chem., 158, 551 (1945).

126. Chu, E. J., Synthesis of Compounds of Related to Vitamin K. III. 4-(3´-Methyl-4´-hydroxynaphthylazo-benzenesulfonamide and Related Compounds, J. Am. Chem. Soc., 67, 811 (1945).

127. Hac, L. R., E. E. Snell, The Microbiological Determination of Amino Acids. III. Assay of Aspartic Acid with Leuconostoc mesenteroides, J. Biol. Chem., 159, 291 (1945).

128. Cunningham, E., and E. E. Snell, The Vitamin B6 Group. VI. The Comparative Stability of Pyridoxine, Pyridoxamine, and Pyridoxal, J. Biol. Chem., 158, 491 (1945).

129. Snell, E. E., The Vitamin B6 Group. VII. Replacement of Vitamin B6 for some Micro-organisms by d(–)-Alanine and an Unidentified Factor from Casein, J. Biol. Chem., 158, 497 (1945).

130. Shive, W., and E. E. Snell, Growth Inhibition by Analogues of Pantothenic Acid. II. α- and β-Substituted Pantothenic Acids and Related Compounds. Science, 102, 401 (1945).

131. Williams, R. J., “Starring” in American Men of Science in Relation to the Status of Chemistry, Science, 101, 222–3 (1945).

132. Williams, R. J., The Clinical Possibilities of Pantothenic Acid, Dietotherapy—Clinical Application of Modern Nutrition (M. G. Wohl, ed.), W. B. Saunders Co., Philadelphia, 263–90 (1945).

133. Chu, E. J. H., Nutritional Requirements of Drosophila Hydei., Texas Rpts. Biol. Med., 3, 4, 513–527 (1945).

134. Snell, E. E., The Nutritional Requirements of the Lactic Acid Bacteria and Their Application to Biochemical Research, J. Bact., 50, 373 (1945).

135. Williams, R. J., What to Do About Vitamins, (Book) 1945, University of Oklahoma Press, Norman.

Biochemical Institute Studies III—Cancer Studies, Univ. Texas Publ. 4507 (1945).

136. Williams, R. J., A Broad Approach to the Cancer Problem, 7–12. 137. Taylor, A., A. Kynette, and R. E. Hungate, Demonstration of a Virus-like Tumor Agent by

Filtration and Desiccation of Materials from Eggs Bearing Mouse Mammary Carcinoma, 13–32.

138. Taylor, A., and A. Kynette, Evidence for a Cancer Virus Using Intraocular Implants of Mouse Tumor in Rats, 33–42.

139. Taylor, A., The Virus Concept in Cancer Res., 43–46. 140. Thompson, R. C., and B. B. Morgan, Factors Affecting the Propagation of Cancers in

Incubating Eggs, 47–52. 141. Hungate, R. E., and H. Snider, The Nutritional Adequacy of the Embryonated Egg for

Growth of a Mammalian Tumor, 53–64. 142. Kynette, A., A. Taylor, and R. C. Thompson, Effects of Egg Grown Heterologous Tumor

Tissue on the Chick Embryo, 65–74.

143. Hungate, R. E., H. Snider, A. Taylor, and R. C. Thompson, Results of Injecting Mice with Fresh Materials from Tumor-bearing Eggs, 75–90.

144. Hungate, R. E., The Effectiveness of Moderate Centrifugation for Separating Tumor Cells from Yolk, 91–94.

145. Taylor A., Changes in Hemoglobin Concentration, Total Hemoglobin, and Blood Volume Associated with Tumor Growth, 95–102.

146. Hungate, R. E., Observations on Effects of Tumor Cells on Hemoglobin in Vitro, 103–104. 147. Hungate, R. E., and H. Snider, Experiments on the Transplantation of C3H and dba

Mammary Carcinomas into the Donor and Non-donor Strains, 105–108. 148. Hungate, R. E., and H. Snider, Experiments on Factors Inhibiting the Growth of

Mammalian Tumors in Eggs, 109–118. 149. Taylor, A., and R. J. Williams, Diet and Spontaneous Lung Tumors in Strain A Mice, 119–

22. 150. Loo, Y. H., and R. J. Williams, A Study of Folic Acid Distribution with Respect to Its

Possible Relationship to Cancer, 123–34. 151. Williams, R. J., Achieving Full Employment After the War, Science, 101, 537–8 (1945). 152. Hac, L. R., E. E. Snell, and R. J. Williams, The Microbiological Determination of Amino

Acids. II. Assay and Utilization of Glutamic Acid and Glutamine by Lactobacillus arabinosus, J. Biol. Chem., 159, 273–89 (1945).

153. Shive, W., and E. E. Snell, Growth Inhibition by Analogues of Pantothenic Acid. III. N-Pantoylalkylamines and Related Compounds. J. Biol. Chem., 160, 287 (1945).

154. Roberts, E. C., and E. E. Snell, An Improved Medium for Microbiological Assays with Lactobacillus casei, J. Biol. Chem., 163, 2, 499–509 (1946).

155. Shive, W., and J. Macow, Biochemical Transformations as Determined by Competitive Analogue-Metabolite Growth Inhibitions. I. Some Transformations Involving Aspartic Acid, J. Biol. Chem., 162, 451–62 (1946).

156. Shive, W., and E. C. Roberts, Biochemical Transformations as Determined by Competitive Analogue-Metabolite Growth Inhibitions. II. Some Transformations Involving p-Aminobenzoic Acid, J. Biol. Chem., 162, 463–71 (1946).

157. Beerstecher, E., Jr., and W. Shive, Biochemical Transformations as Determined by Competitive Analogue-Metabolite Growth Inhibitions. III. A Transformation Involving Phenylalanine, J. Biol. Chem., 164, 53–61 (1946).

158. Ravel, J. M., and W. Shive, Biochemical Transformations as Determined by Competitive Analogue-Metabolite Growth Inhibitions. IV. Prevention of Pantothenic Acid Synthesis by Cysteic Acid, J. Biol. Chem., 166, 407–15 (1946).

159. Guirard, B. M., E. E. Snell, and R. J. Williams, The Microbiological Determination of Amino Acids. IV. Lysine, Histidine, Arginine and Valine, Proc. Soc. Expt. Biol. Med., 61, 158–61 (1946).

160. Guirard, B. M., E. E. Snell, and R. J. Williams, The Nutritional Role of Acetate for Lactic Acid Bacteria. I. The Response to Substances Related to Acetate, Arch. Biochem., 9, 361–79 (1946).

161. Guirard, B. M., E. E. Snell, and R. J. Williams, The Nutritional Role of Acetate for Lactic Acid Bacteria. II. Fractionation of Extracts of Natural Materials, Arch. Biochem., 9, 381–6 (1946).

162. Eppright, M. A., and R. J. Williams, Effects of Certain Limiting Conditions on the Synthesis of B Vitamins by Yeast, J. Gen. Physiol., 30, 61–72 (1946).

164. Williams, R. J., Fuel Foods That Lack Vitamins, Your Health, 8, 70 (1946). 165. Williams, R. J., The Human Frontier, (Book) 1946, Harcourt Brace, New York. 166. Beerstecher, E., Jr., and W. Shive, Biochemical Transformations as Determined by

Competitive Analogue-Metabolite Growth Inhibitions. V. Prevention of Tyrosine Synthesis by β-2-Thienylalanine, J. Biol. Chem., 167, 49–52 (1947).

167. Taylor, A., and N. Carmichael, Stromal Malignancy in Mouse-Grown Transplants of Egg-Cultivated Mouse Mammary Carcinoma, Cancer Res., 7, 77–81 (1947).

168. Beerstecher, E., Jr., and W. Shive, Prevention of Phenylalanine Synthesis by Tyrosine, J. Biol. Chem., 167, 527–34 (1947).

169. Shive, W., W. W. Ackermann, J. M. Ravel, and J. E. Sutherland, Biosyntheses Involving Pantothenic Acid, J. Am. Chem. Soc., 69, 2567 (1947).

170. Taylor, A., A Further Report on Stromal Malignancy in Mouse-Grown Transplants of Egg-cultivated House Mammary Carcinoma. Fourth International Cancer Research Congress, September, 1947, St. Louis, Missouri. (Published in Acto Unio. Intern. contra. Cancrum).

171. Williams, R. J., Humanics: A Crucial Need, Scientific Monthly, 64, 174–80 (1947). 172. Williams, R. J., The Etiology of Alcoholism: A Working Hypothesis Involving the Interplay

of Heredity and Environmental Factors, Quarterly J. Studies on Alcohol, 7, 567–87 (1947). 173. Williams, R. J., Will Science Meet a New Challenge?, Am. Scientist, 35, 282–6 (1947). 174. Williams, R. J., Biochemical Individuality and Its Implications, Chem. Eng. News, 25,

1112–3 (1947). 175. Eppright, M. A., and R. J. Williams, Factors Not Synthesized by Yeast in the Presence of

Cyanide, Proc. Soc. Biol. Med., 64, 123–5 (1947). 176. Lipmann, F., N. O. Kaplan, G. D. Novelli, L. C. Tuttle, and B. M. Guirard, Coenzyme for

Acetylation, a Pantothenic Acid Derivative, J. Biol. Chem., 167, 869–70 (1947). 177. Beerstecher, E., Jr., and W. Shive, Tryptophan as a Competitive Growth Inhibiting Analog

of Phenylalanine, J. Am. Chem. Soc., 69, 461 (1947). 178. Shive, W., W. W. Ackermann, M. Gordon, M. E. Getzendaner, and R. E. Eakin, 5 (4)-

Amino-4(5)-Imidazolecarboxamide, A Precursor of Purines. J. Am. Chem. Soc., 69, 725 (1947).

179. Rogers, L. L., and W. Shive, Biochemical Transformations as Determined by Competitive Analogue-Metabolite Growth Inhibitions. VI. Prevention of Biotin Synthesis by 2-Oxo-4-Imidazolidinecaproic Acid., J. Biol. Chem., 169, 57 (1947).

180. Shive, W., and L. L. Rogers, Involvement of Biotin in the Biosynthesis of Oxalacetic and α-Ketoglutaric Acids. J. Biol. Chem., 169, 453–4 (1947).

181. Taylor, A., N. Carmichael, and T. Norris. Temperature Level and the Growth of Embryo and Tumor of Tumor-Bearing Eggs, Proc. Soc. Exptl. Bio. Med., 66, 165 (1947).

182. Williams, R. J., and H. Kirby, Paper Chromatography Using Capillary Ascent, Science, 107, 481–3 (1948).

183. Williams, R. J., and R. C. Thompson, A Device for Obtaining a Continuous Record of Body Temperature from the External Auditory Canal, Science, 108, 90–1 (1948).

184. Lane, R. L., and R. J. Williams, Inositol, An Active Constituent of Pancreatic (alpha) Amylase, Arch. Biochem., 19, 329–35 (1948).

185. Ravel, J. M., R. E. Eakin, and W. Shive. Glycine, A Precursor of 5(4)-Amino-4(5)Imidazolecarboxamide. J. Biol. Chem., 172, 67 (1948).

186. Rogers, L. L., and W. Shive. Biochemical Transformations as Determined by Competitive Analogue-Metabolite Growth Inhibitions. VII. Relationship of Purines and Thymine to Folic Acid., J. Biol. Chem., 172, 751 (1948).

187. Taylor, A., and N. Carmichael, Yolk Sac Cultivated Tumor Tissue and Experiments in Tumor Chemotherapy. I. Riboflavin. Texas Rpts. Biol. Med., 6, 504–12 (1948).

188. Williams, R. J., Alcoholics and Metabolism, Scientific Am., 179, 50–53 (1948). 189. Gordon, M., J. M. Ravel, R. E. Eakin, and W. Shive. Formylfolic Acid, A Functional

Derivative of Folic Acid, J. Am. Chem. Soc., 70, 878 (1948). 190. Ackermann, W. W., and A. Taylor, Application of a Metabolic Inhibitor to the Developing

Chick Embryo. Proc. Soc. Exptl. Biol. Med., 67, 449–452 (1948). 191. Harding, W. M., and W. Shive, Biochemical Transformations as Determined by

Competitive Analogue-Metabolite Growth Inhibitions. VIII. An Interrelationship of Methionine and Leucine, J. Biol. Chem., 174, 743–56 (1948).

192. Brewster, R. Q., and R. J. Williams, A Laboratory Manual of Organic Chemistry (Book) 1928, 2nd ed. 1934, 3rd ed. 1939, 4th ed. 1948, D. Van Nostrand Co., Inc., New York.

193. Thompson, R. C., and H. M. Kirby. The Microbiological Assay of Extracts Containing Toxic Materials. Arch. Biochem., 18, 127–30 (1948).

194. Ackerman, W. W., and H. M. Kirby. Evidence for the Natural Occurrence of α-Amino-β,β-Dimethyl-γ-Hydroxybutyric Acid (Pantonine). J. Biol. Chem., 175, 483–4 (1948).

195. Shive, W., R. E. Eakin, W. M. Harding, J. M. Ravel, and J. E. Sutherland, A Crystalline Factor Functionally Related to Folic Acid. J. Am. Chem. Soc., 70, 2299 (1948).

196. Ackermann, W. W., and W. Shive, α-Amino-β, β-Dimethyl-γ-Hydroxybutyric Acid; A Precursor of Pantoic Acid., J. Biol. Chem., 175, 867–70 (1948).

197. Shive, W., J. M. Ravel, and R. E. Eakin, An Interrelationship of Thymidine and Vitamin B12. J. Am. Chem. Soc., 70, 2614 (1948).

198. Wagner, R. P., and B. M. Guirard. A Gene-Controlled Reaction in Neurospora Involving the Synthesis of Pantothenic Acid. Proc. Natl. Acad. Sci., 34, 398 (1948).

199. Shive, W., J. M. Ravel, and W. M. Harding. An Interrelationship of Purines and Vitamin B12. J. Biol. Chem., 176, 991 (1948).

200. Taylor, A., N. Carmichael, and T. Norris. A Further Report on Yolk Sac Cultivation of Tumor Tissue. Cancer Res., 8, 264–9 (1948).

201. Blumel, J., and H. M. Kirby. Amino Acid Constituents of Tissues and Isolated Chromosomes of Drosophila. Proc. Natl. Acad. Sci., 34, 561–6 (1948).

202. Williams, R. J., and E. Beerstecher, Jr., An Introduction to Biochemistry, (Book) 2nd edit., 1948, D. Van Nostrand Co., Inc., New York.

203. Williams, R. J., L. J. Berry, and E. Beerstecher, Jr., Individual Metabolic Patterns, Alcoholism, Genetotrophic Diseases, Proc. Natl. Acad. Sci., 35, 265–71 (1949).

204. Williams, R. J., Shall We Pioneer Too? Proc. Philosophical Soc. of Texas, 5–26 (1949). 205. Berry, H. B., and L. Cain. Biochemical Individuality. IV. A Paper Chromatographic

Technique for Determining Excretion of Amino Acids in the Presence of Interfering Substances. Arch. Biochem., 24, 179–89 (1949).

206. Thompson, R. C., and H. M. Kirby. Biochemical Individuality. II. Variation in the Urinary Excretion of Lysine, Threonine, Leucine, and Arginine. Arch. Biochem., 21, 210–6 (1949).

207. Taylor, A., and N. Carmichael. The Effect on the Embryo of Continued Serial Tumor Transplantation in the Yolk Sac. Cancer Res., 9, 498–503 (1949).

208. Taylor, A., and N. Carmichael. Male Mice Tolerate Dosages of Pteroylglutamic Acid Lethal to Females. Proc. Soc. Exptl. Biol. Med., 71, 544 (1949).

209. Beerstecher, E., Jr., Contributions of Natural Science to the Program of Home Life Education in the Junior College. Report of the 8th Annual Junior College Conference-Laboratory, Univ. Texas, June, (1949).

210. Bardos, T. J., T. J. Bond, J. Humphreys, and W. Shive. Relationship of the Folinic Acid Group and the Leuconostoc citrovorum Factors. J. Am. Chem. Soc., 71, 3852 (1949).

211. Bond, T. J., T. J. Bardos, M. Sibley, and W. Shive. The Folinic Acid Group, a Series of New Vitamins Related to Folic Acid. J. Am. Chem. Soc., 71, 3852 (1949).

212. Ternberg, J. L., and R. E. Eakin. Erythein and Apoerythein and their Relation to the Antipernicious Anemia Principle. J. Am. Chem. Soc., 71, 3858 (1949).

213. Williams, R. J., L. J. Berry, and E. Beerstecher, Jr., Biochemical Individuality. III. Genetotrophic Factors in the Etiology of Alcoholism. Arch. Biochem., 23, 275–90 (1949).

214. Taylor, A., and I. Galinsky, Yolk Sac Cultivated Tumor Tissue and Experiments in Tumor Chemotherapy. II. Neutral, Red. Ethyl Violet and Janus Green. Cancer Res., 9, 622 (1949).

215. Beerstecher, E., Jr., Bacterial Inhibition by a Penicillin Moiety. Proc. Soc. Exptl. Biol. Med., 73, 200–201 (1950).

216. Beerstecher, E. Jr., The Comparative Biochemistry of Vitamin Function. Science, 111, 300–302 (1950).

217. Reed, L. J., The Occurrence of γ-Aminobutyric Acid in Yeast Extract: Its Isolation and Identification. J. Biol. Chem., 183, 451–58 (1950).

218. Beerstecher, E. Jr., The Effects of Tropical Acclimatization Upon the Female Menstrual Cycle. Am. J. Trop. Med., 30, 469–71 (1950).

219. Beerstecher, E. Jr., A Simple Procedure for the Determination of Microgram Amounts of Cyanide. The Analyst, 75, 280–281 (1950).

220. Shive, W., The Utilization of Antimetabolites in the Study of Biochemical Processes in Living Organisms, Annals New York Acad. Sci., 52, 1212–34 (1950).

221. Taylor, A., The Use of Yolk Sac Cultivated Tumors in Cancer Chemotherapy Studies. Texas Rpts. Biol. Med., 8, 227–237 (1950).

222. Williams, R. J., E. Beerstecher, Jr., L. J. Berry, The Concept of Genetotrophic Disease, The Lancet, 287–9 (Feb. 18, 1950).

223. Williams, R. J. L. J. Berry, and E. Beerstecher, Jr., Genetotrophic Diseases: Alcoholism, Texas Rpts. Biol. Med., 8, 238 (1950).

224. Williams, R. J., R. E. Eakin, E. Beerstecher, Jr., and W. Shive, The Biochemistry of B Vitamins, Am. Chem. Soc. Monograph No. 110, Reinhold Publishing Corp., N.Y. (1950).

225. Williams, R. J., Concept of Genetotrophic Disease, Nutrition Rev., 8, 9, 257–260 (Sept. 1950).

226. Williams, R. J., Men and Marbles (address), Am. Chem. Soc. Regional Award Address, Southwest Report, 16–18 (January, 1951).

227. Shive, W., T. J. Bardos, T. J. Bond, and L. L. Rogers. Synthetic Members of the Folinic Acid Group. J. Am. Chem. Soc., 72, 2817 (1950).

228. Thompson, R. C., and M. Abdulnabi. A Study of the Urinary Excretion of α-Amino Nitrogen and Lysine by Humans. J. Biol. Chem., 185, No. 2, 625–8 (1950).

229. Beerstecher, E. Jr., Micromethod for Estimation of Potassium by Paper Chromatography. Anal. Chem., 22, 1200 (1950).

230. Beerstecher, E., Jr., H. E. Sutton, H. K. Berry, W. D. Brown, J. Reed, G. B. Rich, L. J. Berry, and R. J. Williams. Biochemical Individuality V. Explorations with Respect to the Metabolic Patterns of Compulsive Drinkers. Arch. Biochem., 29, 27–40 (1950).

231. Beerstecher, E. Jr., and H. E. Sutton. Urography: A New Technique in the Study of Individual Metabolic Spectra. Texas Rpts. Biol. Med., 9, 8–12 (1951).

232. Shive, W., M. E. Sibley, and L. L. Rogers. Replacement of Vitamin B12 by Desoxynucleotides in Promoting Growth of Certain Lactobacilli. J. Am. Chem. Soc., 73, 867 (1951).

233. Flynn, E. H., T. J. Bond, T. J. Bardos, and W. Shive. A Synthetic Compound with Folinic Acid Activity. J. Am. Chem. Soc., 73, 1979 (1951).

234. Reed, L. J., B. G. DeBusk, I. C. Gunsalus, and C. S. Hornberger, Jr., Crystalline α-Lipoic Acid: A Catalytic Agent Associated with Pyruvate Dehydrogenase, Science, 114, 93–94 (1951).

235. May, M., T. J. Bardos, F. L. Barger, M. Lamford, J. M. Ravel, G. L. Sutherland, and William Shive. Synthetic and Degrative Investigations of the Structure of Folinic Acid-SF. J. Am. Chem. Soc., 73, 3067 (1951).

236. Taylor, A., and N. Carmichael. Folic Acid Analogs and the Growth of Embryo and Tumor Tissue. Cancer Res., 11, 519–522 (1951).

237. Cheldelin, V. H., A. P. Nygaard, H. A. Kornberg, and R. J. Williams. Vitamin B6 Phosphates, Growth Factors for Leuconostoc mesenteroides. J. Bact., 62, 134–135 (1951).

238. Pohland, A., E. H. Flynn, R. G. Jones, and W. Shive. A Proposed Structure for Folinic Acid-SF, A Growth Factor Derived from Pteroylglutamic Acid. J. Am. Chem. Soc., 73, 3247 (1951).

239. Williams, R. J., Nutrition and Alcoholism, (Book) The Univ. of Oklahoma Press, Norman (1951).

241. Williams, R. J., The Unexplored Field of Genetotrophic Disease, MD, 6, 123–4, 136 (1951). 242. Reed, L. J., B. G. DeBusk, P. M. Johnston, and M. E. Getzendaner. Acetate-Replacing

Factors for Lactic Acid Bacteria. I. Nature, Extraction and Distribution. J. Biol. Chem., 192, 851–58 (1951).

243. Reed, L. J., M. E. Getzendaner, B. G. DeBusk, and P. M. Johnston. Acetate-Replacing Factors for Lactic Acid Bacteria. II. Purification and Properties. J. Biol. Chem., 192, 859–65 (1951).

244. Reed, L. J., B. G. DeBusk, I. C. Gunsalus and G. H. F. Sehnakenberg. Chemical Nature of alpha-Lipoic Acid. J. Am. Chem. Soc., 73, 5920 (1951).

245. Reed, L. J., and M. J. Cormier. Acetate-Replacing Factors for Lactic Acid Bacteria: Intracellular Distribution in Rat Liver. Soc. Exptl. Biol. Med., 77, 724–5 (1951).

Biochemical Institute Studies IV—Individual Metabolic Patterns and Human Disease: An

Exploratory Study Utilizing Predominantly Paper Chromatographic Methods, Univ. Texas Publ. 5109 (1951).

246. R. J. Williams, Introduction, General Discussion and Tentative Conclusions, 7–22. 247. Berry, H. K., H. E. Sutton, L. Cain, and J. S. Berry. Development of Paper Chromatography

for Use in the Study of Metabolic Patterns, 22–55. 248. Jirgensons, B. The Influence of Solvent Composition, Temperature and Some Other Factors

on the Rf Values of Amino Acids in Paper Chromatography, 56–70.

249. Berry, H. K., and L. Cain. Quantitative Study of Urinary and Salivary Amino Acids Using Paper Chromatography, 71–76.

250. Cain, L., and H. K. Berry. The Quantitative Determination of Histidine Using Paper Chromatography, 77–79.

251. Berry, H. K., and L. Cain. The Quantitative Determination of Creatinine in Urine Using Paper Chromatography, 80–81.

252. Cain, L. The Quantitative Determination of Creatine in Urine by Paper Chromatography, 82–83.

253. Berry, H. K. The Quantitative Estimation of Uric Acid by Paper Chromatographic Methods, with Applications to Human Urine and Saliva, 84–87.

254. Berry, H. K. The Quantitative Estimation of Urea by Paper Chromatographic Methods with Applications to Human Urine, 88–92.

255. Sutton, H. E. A Micro Determination of Sodium Using Paper Chromatography, 93–96. 256. Bloch, E., E. Beerstecher, Jr., and R. C. Thompson. Quantitative Study of Ketosteroids by

Paper Chromatographic Methods with Applications to Human Urine, 97–108. 257. Sutton, H. E., and E. Beerstecher, Jr. The Determination of Ferric Chloride Chromogens in

Human Urine by Paper Chromatographic Methods, 109–114. 258. Beerstecher, E., Jr., J. G. Reed, W. D. Brown, and L. J. Berry. The Effects of Single

Vitamin Deficiencies on the Consumption of Alcohol by White Rats, 115–138. 259. Reed, J. G. Individual Excretion Patterns in Laboratory Rats, 139–143. 260. Reed, J. G. A Study of the Alcoholic Consumption and Amino Acid Excretion Patterns of

Rats of Different Inbred Strains, 144–149. 261. Berry, H. K., L. Cain, and L. L. Rogers. A Study of the Urinary Excretion Patterns of Six

Human Individuals, 150–156. 262. Berry, H. K. Further Studies on Individual Urinary and Salivary Amino Acid Patterns, 157–

164. 263. Berry, H. K., and L. Cain. Individual Urinary Excretion Patterns of Young Children, 165–

172. 264. Sutton, H. E. A Further Study of Urinary Excretion Patterns in Relation to Diet, 173–180. 265. Brown, J. D. and E. Beerstecher, Jr. Metabolic Patterns of Underweight and Over-weight

Individuals, 181–188. 266. Young, M. K., Jr., H. K. Berry, E. Beerstecher, Jr., and J. S. Berry. Metabolic Patterns of

Schizophrenic and Control Groups, 189–197. 267. Cain, L. Exploration of Metabolic Patterns in Mentally Deficient Children, 198–205. 268. Taylor, A., N. Carmichael, G. F. McKenna, and N. M. Burlage. Inhibition of the Growth of

Egg Cultivated Tissue by Extracts of Cooperia pedunculata Herb. Proc. Soc. Exptl. Biol. Med., 77, 841–843 (1951).

269. Klatt, O. A., and A. Taylor. The Effect of Tumor Growth on Liver Catalase Concentration. Cancer Res., 11, 764–767 (1951).

270. Shive, W. B-Vitamins and the Biosyntheses of Purines and Pyrimidines. J. Cell. and Comp. Physiol., 38, supplement 1, 203 (1951).

271. Shive, W. The Functions of B-Vitamins in the Biosynthesis of Purines and Pyrimidines. Vitamins and Hormones, IX, 75–130 (1951).

272. Radin, N. S. α-Lipoic Acid in Oxidative Reactions of a Corynebacterium. Proc. Soc. Exptl. Biol. Med., 79, 723–726 (1952).

273. Walker, J. B. Arginosuccinic Acid from Chlorella. Proc. Natl. Acad. Sci., 38, 561–566 (1952).

274. Radin, N. S. Apparatus for Distillation and Stirring. Anal. Chem., 24, no. 10, 1686 (Oct. 1952).

275. Williams, R. J. Nutritional Vulnerability and Alcoholism, Research Reviews, 4–8 (1952). 276. Williams, R. J. Alcoholism as a Nutritional Problem, J. Clin. Nutr., 32 (Sept.–Oct. 1952). 277. Hornberger, C. S., Jr., R. F. Heitmiller, I. C. Gunsalus, O. H. F. Schnakenberg, and L. J.

Reed. Synthetic Preparation of Lipoic Acid. J. Am. Chem. Soc., 74, 2382 (1952). 278. Reed, L. J., Q. F. Soper, G. H. F. Schnakenberg, S. F. Kern, H. Boaz, I. C. Gunsalus.

Identification of the Carbon Skeleton of α-Lipoic Acid. J. Am. Chem. Soc., 74, 2383 (1952). 279. Reed, L. J., and B. G. DeBusk, Lipothiamide and its Relation to a Thiamin Coenzyme

Required for Oxidative Decarboxylation of α-Keto Acids. J. Am. Chem. Soc., 74, 3457 (1952).

280. Reed, L. J., and B. G. DeBusk. Lipothiamide Pyrophosphate: Coenzyme for Oxidative Decarboxylation of α-Keto Acids. J. Am. Chem. Soc., 74, 3964 (1952).

281. Reed, L. J., and B. G. DeBusk. Lipoic Acid Conjugase. J. Am. Chem. Soc., 74, 4727 (1952).

282. Reed, L. J., and B. G. DeBusk. A Conjugate of α-Lipoic Acid Required for Oxidation of Pyruvate and α-Ketoglutarate by an Escherichia coli Mutant. J. Biol. Chem., 199, 873 (1952).

283. Reed, L. J., and B. G. DeBusk. Chemical Nature of an α-Lipoic Acid Conjugate Required for Oxidation of Pyruvate and α-Ketoglutarate by an Escherichia coli mutant. J. Biol. Chem., 199, 881 (1952).

284. Snell, E. E. Correlation of Chemical Enzymatic and Growth-Promoting Properties of Vitamin B6. Symposium sur le Metabolism Microbien, II. Congres International de Biochimie. Paris, July 21–27, pp. 47–63 (1952).

285. Kihara, H., W. G. McCullough, and E. E. Snell. Peptides and Bacterial Growth. I. Purification of a Peptide Factor required for Growth of Lactobacillus casei. J. Biol. Chem., 197, 783–789 (1952).

286. Kihara, H., and E. E. Snell. Peptides and Bacterial Growth, II. L-Alanine Peptides and Growth of Lactobacillus casei J. Biol. Chem., 197, 791–800 (1952).

287. Kihara, H., O. A. Klatt, and E. E. Snell. Peptides and Bacterial Growth. III. Utilization of Tyrosine and Tyrosine Peptides by Streptococcus faecalis J. Biol. Chem., 197, 801–807 (1952).

288. Lansford, E. M., Jr., and W. Shive. The Microbiological Activity of N-(DL-Pantonyl) β-Alanine. J. Biol. Chem., 194, 329–336 (1952).

289. Metzler, D. E., and E. E. Snell. Deamination of serine I. Catalytic deamination of serine and cysteine by pyridoxal and metal salts. J. Biol. Chem., 198, 353–361 (1952).

290. Metzler, D. E., and E. E. Snell. Deamination of serine II. D-Serine Dehydrase, a Vitamin B6 Enzyme from Escherichia coli. J. Biol. Chem., 198, 363–373 (1952).

291. Brown, G. M., and E. E. Snell. The relationship of Pantethine to naturally Occurring Forms of the Lactobacillus bulgaricus factor. J. Biol. Chem., 198, 375–383 (1952).

292. Naher, E. C., E. E. Snell, and W. W. Cravens. Effects of nucleic Acid Derivatives in the Reversal of Aminopterin Inhibition in the Chick Embryo, Proc. Soc. Exptl. Biol. Med., 81, 20–23 (1952).

293. Olivard, J. D. E. Metzler, and E. E. Snell. Catalytic Racemization of Amino Acids by Pyridoxal and Metal Salts. J. Biol. Chem., 199, 669–674 (1952).

294. Tittsler, R. P., C. S. Pederson, E. E. Snell, D. Hendlin, and C. F. Niven, Jr. Symposium on the Lactic Acid Bacteria. Bacteriol. Reviews, 16, 227–260 (1952).

295. Lamford, E. M., Jr., and W. Shive. Growth Inhibition by some β-Arylalanines, Arch. Biochem. and Biophys., 38, 347–351 (1952).

296. Lansford, E. M., Jr., and W. Shive. Microbiological Activity of α-Keto-β,β-dimethyl-7-butyrolactone. Arch. Biochem. and Biophys., 38, 353–355 (1952).

297. Shive, W. Inhibition Analysis as a Method of Vitamin Research. International Review of Vitamin Research, 23, 3, 392–404 (1952).

298. Shive, W. Biological Activities of Metabolite Analogues. Annual Review of Microbiology, 6, 437–466 (1952).

299. Williams, R. J., and W. Wenner. Pantothenic Acid, Encyclopedia of Chemical Technology, 9, The Interscience Encyclopedia, Inc., 805–811 (1952).

300. Taylor, A., G. D. McKenna, and H. M. Burlage. Cancer Chemotherapy Experiments with Plant Extracts. Texas Rpts. Biol. Med., 10, No. 4, 1062–74 (1952).

301. Knox, J. C., Jr., H. F. Rosene, and A. Taylor. The Effect of Various Tumor Growths on the Water Content of the Liver in Mice and Chick Embryos. Texas Rpts. Biol. Med., 10, No. 4, 830–844 (1952).

302. Burlage, H. M., M. E. Jones, G. F. McKenna, and A. Taylor. Studies on Toxic Plants for Antibacterial Effects. Texas Rpts. Biol. Med., 10, No. 4, 803–815 (1952) Winter.

303. Li, Si-Oh. Synthesis of N-Phosphoryl Amino Esters, J. Am. Chem. Soc., 74, 5959 (1952). 304. Snell, E. E., and J. C. Rabinowitz. Vitamin Bo Antagonists and Growth of Microorganisms.

I. 4-Desoxypyridoxine. Arch. of Biochem. and Biophys., 43, No. 2, 399–407 (1952). 305. Snell, E. E., and J. C. Rabinowitz. Vitamin B6 Antagonists and Growth of Microorganisms.

II. 5-Desoxypyridoxal and Related Compounds, Arch. Biochem. and Biophysics., 43, No. 2, (1952).

306. Williams, R. J. Muscular Dystrophy and Individual Metabolic Patterns: The Possibilities of a Nutritional Therapeutic Approach, Proc. of the First and Second Medical Conferences of the Muscular Dystrophy Assoc. of America, Inc., 118–122, (1953).

307. Williams, R. J. Free and Unequal, (Book) Univ. of Texas Press, Austin (1953). 308. Williams, R. J., and L. L. Rogers. The Formulation of a Genetotrophic Supplement for the

Experimental Treatment of Diseases of Obscure Etiology, Texas Rpts. Biol. Med. 11, 573–581 (1953).

309. Williams, R. J. Biochemistry Moves Toward Human Understanding (An Abstract) Symposium of B Vitamins, Biochem. Institute, Univ. of Texas (1953).

310. Taylor, A., and G. F. McKenna. The Use of Yolk Sac Cultivated Bacteria in Bacterial Studies, Texas Rpts. Biol. Med., 11, No. 2, 283–286 (1953).

311. Shive, W. B-Vitamins Involved in Single Carbon Unit Metabolism, Fed. Proc., 12, No. 2, 639–646 (1953).

312. Snell, E. E., and G. M. Brown. Pantethine and Related Forms of the Lactobacillus Bulgaricus Factor (LBF). Advances in Enzymology, Interscience Publishers, Inc., XIV. 49–71 (1953).

313. Snell, E. E., and J. C. Rabinowitz. The Microbiological Activity of Pyridoxylamines, J. Am. Chem. Soc., 75, 998 (1953).

314. Snell, E. E., E. L. Whittle, J. A. Moore, R. W. Stipek, F. E. Peterson, V. M. McGlohon, O. D. Bird, G. M. Brown. The Synthesis of Pantetheine-Pantethine, J. Am. Chem. Soc., 75, 1694–1700 (1953).

315. Snell, E. E., and G. M. Brown. The Chemical Nature of the Lactobacillus Bulgaricus Factor, J. Am. Chem. Soc., 75, 1691–1693 (1953).

316. Snell, E. E., V. J. Peters, G. M. Brown, and W. L. Williams. Isolation of the Lactobacillus Bulgaricus Factor from Natural Sources, J. Am. Chem. Soc., 75, 1688–1691 (1953).

317. Reed, L. J., I. C. Gunsalus, G. H. F. Schnakenberg, Q. F. Soper, H. E. Boaz, S. F. Kern, and T. V. Parke. Isolation, Characterization and Structure of alpha-Lipoic Acid. J. Am. Chem. Soc., 75, 1267–1270 (1953).

318. Reed, L. J., B. G. DeBusk, C. S. Hornberger, Jr., and I. C. Gunsalus. Interrelationships of Lipoic Acids. J. Am. Chem. Soc., 75, 1271–1273 (1953).

319. Hornberger, C. S. Jr., R. F. Heitmiller, I. C. Gunsalus, G. H. F. Schakenberg, and L. J. Reed. Synthesis of DL-alpha-Lipoic Acid, J. Am. Chem. Soc., 75, 1273–1277 (1953).

320. Reed, L. J., and B. G. DeBusk. Mechanism of Enzymatic Oxidative Decarboxylation of Pyruvate, J. Am. Chem. Soc., 75, 1261 (1953).

321. Snell, E. E., O. A. Klatt, H. W. Bruins, and W. W. Cravens. Growth-Promotion by Lyxoflavin. II. Relationship to Riboflavin in Bacteria and Chicks. Soc. Exptl. Biol. Med., 82, 583–590 (1953).

322. Peters, V. J., J. M. Prescott, and E. E. Snell. Peptides and Bacterial Growth. IV. Histidine Peptides as Growth Factors for Lactobacillus delbrneckii 9649. J. Biol. Chem., 202, No. 2, 521–532 (1953).

323. Prescott, J. M., V. J. Peters, and E. E. Snell. Peptides and Bacterial Growth. V., Serine Peptides and Growth of Lactobacillus delbrueckii 9649. J. Biol. Chem., 202, No. 2, 533–540 (1953).

324. Brown, G. M., and E. E. Snell. N-Pantothenylcysteine as a Precursor for Pantetheine and Coenzyme A., J. Am. Chem. Soc., 75, 2872 (1953).

325. Metzler, D. E., J. B. Longenecker, and E. E. Snell. Reversible Catalytic Cleavage of Hydroxyamino Acids by Pyridoxal and Metal Salts, J. Am. Chem. Soc., 75, 2786 (1953).

326. Walker, J. B., and J. Myers. The Formation of Argniosuccinic Acid from Arginine and Fumarate, J. Biol. Chem., 203, 1,143–153 (1953).

Biochemical Institute Studies V—Cancer Studies II, Univ. of Texas Publ. 5314 (1953).

327. Taylor, A. Cancer Etiology, 1–12. 328. Taylor, A. The Yolk Sac Method of Cultivating Tumor Tissue in Eggs, 13–26. 329. Taylor, A. The Use of Embryonated Eggs in Cancer Therapy Experiments, 27–35. 330. Taylor, A., and N. Carmichael. The Effect of Metallic Chlorides on the Growth of Tumor

and Non-Tumor Tissue, 36–79. 331. Young, M. K., and A. Taylor. Factors Influencing the Utilization of Glucose by

Suspensions of Living Tumor and Embryonic Cells, 80–88. 332. Reed, L. J., and B. G. DeBusk. Enzymes and Cofactors Functioning in Oxidative

Decarboxylation of α-Keto Acids, (An Abstract), Symposium on B Vitamins, Biochemical Institute, University of Texas (1953).

333. Walker, J. B., Inorganic Micronutrient Requirements of Chlorella. I. Requirements for Calcium (or Strontium), Copper and Molybdenum. Arch. Biochem. Biophysics, 46, 1, 1–11 (1953).

334. Walker, James B., An Enzymatic Reaction Between Canavine and Fumarate, J. Biol. Chem., 204, 1, 103–146 (1953).

335. Broquist, H. P., and E. E. Snell. Biotin and Bacterial Growth. II. Avidin and the Response of Lactobacillus arabinosus to Oleic Acid, Archives of Biochemistry and Biophysics, 46, 2, 432–442 (1953).

336. Reed, L. J. Metabolic Functions of Thiamine and Lipoic Acid, Physiological Reviews, 33, 544–559 (1953).

337. Berry, H. K. Variations in Urinary Excretion Patterns in a Texas Population. Am. J. Phys. Anthrop., n.s. 11, 4, 559–575 (1953).

338. Snell, E. E. Summary of Known Metabolic Functions of Nicotinic Acid, Riboflavin and Vitamin B6, Physiological Reviews, 33, 4, 509–524 (1953).

339. Weaver, J. M., and W. Shive. Involvement of Thymidine in the Utilization of 5-Amino-4-imidazolecarboxamide, J. Am. Chem. Soc., 75, 4628 (1953).

340. Taylor, A., and N. Carmichael, Egg Cultivated Tumor Protects Embryo Against Vaccinia Virus, Proc. Soc. Exptl. Biol. Med., 83, 676–678 (1953).

341. Metzler, D. E., M. Ikawa, and E. E. Snell. Reactions of Pyridoxal With Amino Acids, An Abstract, Symposium on B Vitamins, Biochemical Institute, University of Texas, (1953).

342. Eakin, R. E. In Vitro Studies of B12-Binding Proteins, An Abstract, Symposium on B Vitamins, Biochemical Institute, University of Texas, (1953).

343. Lansford, E. M., J. M. Weaver, R. M. Trubey, and W. Shive. Studies on Thymidine Function and Distribution in Tissues, An Abstract, Symposium on B Vitamins, Biochemical Institute, University of Texas, (1953).

344. Brown, G. M., and E. E. Snell. Microbiological Activity and Biosynthesis of Pantethine and Related Compounds, An Abstract, Symposium on B Vitamins, Biochemical Institute, University of Texas, (1953).

345. Walker, J. B. Metabolism of Arginosuccinic and Canavanosuccinic Acids, An Abstract, Symposium on B Vitamins, Biochemical Institute, University of Texas, (1953).

346. Dien, L. T. H., J. M. Ravel, and W. Shive. Some Inhibitory Interrelationships among Leucine, Isoleucine and Valine, Archives of Biochem. Biophysics, 49, 2, 283–292 (1954).

347. Brown, G. M., and E. E. Snell. Pantothenic Acid Conjugates and Growth of Acetobacter Suboxydans, J. Bacteriology, 67, 4, 465–471 (1954).

348. Metzler, D. E., M. Ikawa, and E. E. Snell. A General Mechanism for Vitamin B6-catalyzed Reactions. J. Am. Chem. Soc., 76, 648–652 (1952).

349. Metzler, D. E., J. B. Longenecker, and E. E. Snell. The Reversible Catalytic Cleavage of Hydroxyamino Acids by Pyridoxal and Metal Salts, J. Am. Chem. Soc., 76, 639–644 (1954).

350. Ikawa, M., and E. E. Snell. Benzene Analogs of Pyridoxal. The Reactions of 4-Nitro- salicylaldehyde with Amino Acids, J. Am. Chem. Soc., 76, 653 (1954).

351. Ikawa, M., and E. E. Snell Synthesis and Biological Activity of Homologs of Pyridoxal and Pyridoxamine, J. Am. Chem. Soc., 76, 637 (1954).

352. Metzler, D. E., J. Olivard, and E. E. Snell. Transamination of Pyridoxamine and Amino Acids with Glyoxylic Acid, J. Am. Chem. Soc., 76, 644–648 (1954).

353. Walker, J. B. Inorganic Micronutrient Requirements of Chlorella. II. Quantitative Requirements for Iron, Manganese, and Zinc, Arch. Biochem. and Biophysics, 53, 1, 1–8 (1954).

354. Williams, R. J. The Genetotrophic Concept, Nutritional Deficiencies and Alcoholism, Annals of N. Y. Acad. Sciences, 57, 794–809 (1954).

355. Williams, R. J. Early Experiences with Pantothenic Acid, A retrospect, Nutrition Reviews, 12, 3, 65–68 (1954).

356. Peters, V. J., and E. E. Snell. Peptides and Bacterial Growth. VI. The Nutritional Requirements of Lactobacillus delbrueckii, J. Bact., 67, 1, 69–76 (1954).

357. McRorie, R. A., G. L. Sutherland, M. S. Lewis, A. D. Barton, M. R. Glazeher, and W. Shive. Isolation and Identification of a Naturally Occurring Analog of Methionine, J. Am. Chem. Soc., 76, 115–118 (1954).

358. Harding, W. M., and W. Shive. Cyclopentaneglycine, An Inhibitory Analogue of Isoleucine, J. Biol. Chem., 206, 401–410 (1954).

359. Ravel, J. M., L. Woods, B. Felsing, and W. Shive. Some Interrelationships of Aspartic Acid, Threonine and Lysine, J. Biol. Chem., 206, 391–400 (1954).

360. Ravel, J. M., B. Felsing, and W. Shive. Glutamic Acid Inhibition of Aspartic Acid Utilization in Threonine Biosynthesis, J. Biol. Chem., 206, 2, 791–796 (1954).

361. McKenna, G. F., A. Taylor, and H. M. Burlage. Chemotherapy Experiments with Plant Extracts and Transplantable Tumors, Texas Rpts. Biol. Med., 12, 3, 500–508 (1954).

362. Burlage, H. M., S. M. Gibson, G. IV. McKenna, and A. Taylor. Studies on Toxic Plants for Antibacterial Effects II. Texas Rpts. Biol. Med., 12, 2, 229–235 (1954).

363. Taylor, A., G. IV. McKenna, H. M. Burlage, and Stokes, D. M. Plant Extracts Tested Against Egg Cultivated Viruses, Texas Rpts. Biol. Med., 12, 3, 551–557 (1954).

364. McRorie, R. A., M. R. Glazener, C. G. Skinner, and W. Shive. Microbiological Activity of the Methylsulfonium Derivative of Methionine, J. Biol. Chem., 211, 489–497 (1954).

365. Wahba, A. J., and W. Shive. A Role of Aspartic Acid in Purine Biosynthesis, J. Biol. Chem., 211, 155–161 (1954).

366. Woods, L., J. M. Ravel, and W. Shive. Relationship of Aspartic Acid to Pyrimidine Biosynthesis, J. Biol. Chem., 209, 559–567 (1954).

367. Wahba, A. J., J. M. Ravel, and W. Shive. Involvement of Aspartic Acid in Purine Biosynthesis, Biochem. et Biophy. Acta, 14, 569 (1954).

368. Reed, L. J., and B. G. DeBusk. Enzymatic Synthesis of a Lipoic Acid Coenzyme, Federation Proceedings, 13, 723–731 (1954).

369. Reed, L. J. Availability of Crystalline DL-a-Lipoic Acid, Science, 120, 854 (1954). 370. Ikawa, M., and E. E. Snell. Oxidative Deamination of Amino Acids by Pyridoxal and Metal

Salts, J. Am. Chem. Soc., 76, 4900 (1954). 371. Guirard, B. M., and E. E. Snell. Pyridoxal Phosphate and Metal Ions as Cofactors of

Histidine Decarboxylase, J. Am. Chem. Soc., 76, 4745 (1954). 372. Walker, J. B. Canavanine and Homoarginine as Antimetabolites of Arginine and Lysine in

Yeast and Algae, J. Biol. Chem., 212, 207–215, (1955). 373. Brown, Gene M., M. Ikawa, and E. E. Snell. Synthesis and Microbiological Activity of

Some Pantothenic Acid Conjugates, J. Biol. Chem., 213, 855–867 (1955). 374. Ward, G. B., G. M. Brown, and E. E. Snell. Phosphorylation of Pantothenic Acid and

Pantethine by an Enzyme from Proteus morganii, J. Biol. Chem., 213, 869–876 (1955).

375. Walker, J. B. Homoarginine Inhibition of Escherichia coli B, J. Biol. Chem., 212, 617–621 (1955).

376. Olivard, J., and E. E. Snell. Growth and Enzymatic Activities of Vitamin B6 Analogues. I. D-Alanine Synthesis, J. Biol. Chem., 213, 203–213 (1955).

377. Kihara, H., and E. E. Snell. Peptides and Bacterial Growth. VII. Relation to Inhibitions by Thienylalanine, Ethionine and Canavanine, J. Biol. Chem., 212, 83–94 (1955).

378. Olivard, J., and E. E. Snell. Growth and Enzymatic Activities of Vitamin B6 Analogues. II. Synthesis of Miscellaneous Amino Acids, J. Biol. Chem., 213, 215–228 (1955).

379. Longenecker, J. B., and E. E. Snell. A Possible Mechanism for Kynureninase Action, J. Biol. Chem., 213, 229–235 (1955).

380. Ravel, J. M., B. Felsing, and W. Shive. Comparative Inhibitory Effects of Glutamic and Cysteic Acids on Aspartic Acid Utilization, Arch. Biochem. and Biophysics, 54, 541–548 (1955).

381. Ravel, J. M., and W. Shive. A Study of Biotin Sulfone Inhibition of Lactobacillus arabinosus, Arch. Biochem. and Biophys., 54, 341–348 (1955).

382. Ravel, J. M., B. Felsing, E. M. Lansford, Jr., R. H. Trubey, and W. Shive. Reversal of Alcohol Toxicity by Glutamine, J. Biol. Chem., 214, 497–501 (1955).

383. Lansford, E. M., Jr., and W. Shive. Antimetabolites in Study of Biochemistry of Purines and Pyrimidines. Reprinted from Antimetabolites and Cancer, Am. Assoc. for the Advancement of Science (1955).

384. Reed, L. J., and C. Niu. Syntheses of DL-alpha-Lipoic Acid, J. Am. Chem. Soc., 77, 416 (1955).

385. Li, Si-Oh, and R. E. Eakin. Synthesis of N-Phosphorylated Derivatives of Amino Acids, J. Am. Chem. Soc., 77, 1866 (1955).

386. Dennis, R. L., W. J. Plant, C. G. Skinner, G. L. Sutherland, and W. Shive. Synthesis of 2-Cyclopentene-l-glycine, an Inhibitory Amino Acid Analog, J. Am. Chem. Soc., 77, 2362 (1955).

387. Li, Si-Oh, and R. E. Eakin. Infrared Spectra of N-Phosphorylated Derivatives of Amino Acids, J. Am. Chem. Soc., 77, 3519 (1955).

388. Leach, F. R., K. Yasunobu, and L. J. Reed. Lipoic acid activation of the α-ketobutyrate oxidation system in cell-free extracts of Streptococcus faecalis. Biochim. et Bioph. Acta, 18, 297–298 (1955).

389. Thomas, R. C., and L. J. Reed. Synthesis and Properties of High Specific Activity DL-alpha-Lipoic Acid-S2

35. J. Am. Chem. Soc., 77, 5446–47 (1955). 390. Walker, J. B. Biosynthesis of Canavaninosuccinic Acid from Canavanine and Fumarate in

Kidney. Arch. Biochem. Biophys., 59, 233–245 (1955). 391. Skinner, C. G., and W. Shive. Synthesis of Some 6-(Substituted)-Aminopurines. J. Am.

Chem. Soc., 77, 6692–6693 (1955). 392. Singer, H., and W. Shive. Synthesis of 7-Indolecarboxylic Acid. J. Am. Chem. Soc., 77,

5700–5702 (1955). 393. Singer, H., and W. Shive. Synthesis of Indole Derivatives. 5-Indolecarboxylic Acid. J. Org.

Chem., 20, 1458–1460 (1955). 394. Ravel, J. M., J. L. Reger, and W. Shive. Aspartic Acid Inhibition of Glutamic Acid

Utilization for Proline, Citrulline and Glutamine Biosynthesis. Arch. Biochem. Biophys., 57, 312–322 (1955).

395. Ravel, J. M., and W. Shive. Arginine Inhibition of Glutamate Utilization. Biochimica et Biophysica Acta, 18, 535–539 (1955).

396. Sandman, R., and E. E. Snell. Some Effects of ω-Methyl Analogues of Vitamin B6 in Rats. Proc. Soc. Exptl. Biol. Med., 90, 63–67 (1955).

397. Mitoma, C., and E. E. Snell. The Role of Purine Bases as Histidine Precursors in Lactobacillus casei Proc. Natl. Acad. Sci., 41, 891–894 (1955).

398. Snell, E. E., N. S. Radin, and M. Ikawa. The Nature of D-Alanine in Lactic Acid Bacteria. J. Biol. Chem., 217, 803–818 (1955).

399. Kihara, H., J. M. Prescott, and E. E. Snell. The Bacterial Cleavage of Canavanine to Homoserine and Guanidine. J. Biol. Chem., 217, 497–503 (1955).

400. Hurley, K. E., and R. J. Williams. Urinary Amino Acids, Creatinine, and Phosphate in Muscular Dystrophy, Arch. Biochem. Biophy., 54, 384–391 (1955).

401. DeBusk, B. G., and R. J. Williams. Effect of Lipoic Acid on the Growth Rate of Young Chicks and Rats, Arch. Biochem. Biophy., 55, 587–588 (1955).

402. Williams, R. J., Implications of Humanics for Law and Science, J. Public Law, Emory Univ. Law School, 3, 328–344 (1955).

403. Rogers, L. L., R. B. Pelton, and R. J. Williams. Voluntary Alcohol Consumption by Rats Following Administration of Glutamine, J. Biol. Chem., 214, 503–506 (1955). 404. Williams, R. J., R. B. Pelton, and L. L. Rogers. Dietary Deficiencies in Animals in Relation to Voluntary Alcohol and Sugar Consumption, Quar. J. Studies on Alcohol, 16, 234–244 (June, 1955).

405. Williams, R. J., W. D. Brown, and R. W. Shideler. Metabolic Peculiarities in Normal Young Men as Revealed by Repeated Blood Analyses, Proc. Natl. Acad. Sci.,, 41, 615–620 (1955).

406. Williams, R. J. The Genetotrophic Approach to Alcoholism, Origins of Resistance to Toxic Agents, Proc. of Symposium held in Wash., D. C., March 25–27, 1954. Academic Press, N. Y. (1955).

407. Williams, R. J., and G. B. DeBusk. Overnight Nutritional Responses of Chicks, Proc. Natl. Acad. Sci., 41, 894–899 (1955).

408. Williams, R. J., Biochemical Approach to the Study of Personality. Psychiatric Research Rpts., 2, 31–37 (1955).

409. Taylor, A., and R. J. Williams. The Control of A Cancer Growth In Embryonated Eggs. Proc. Natl. Acad. Sci., 42, 54–60 (1956).

410. Williams, R. J. Human Nutrition and Individual Variability. Borden’s Review of Nutrition Research, 17, 11–26 (1956).

411. Rogers, L. L., R. B. Pelton, and R. J. Williams. Amino Acid Supplementation and Voluntary Alcohol Consumption by Rats, J. Biol. Chem., 220, 321–323 (1956).

412. Williams, R. J. What Is Behavioral Science? Science, 124, 276–277 (1956). 413. Williams, R. J. Biochemical Individuality—An Inescapable Basic Factor in the Alcoholism

Problem (Paper presented at Istanbul, September, 1956, published by International Bureau Against Alcoholism, Lausanne, Switzerland.).

414. Williams, R. J. Biochemical Individuality (Book) John Wiley & Sons, New York, (1956). (Translated into Russian, Italian and Polish.)

415. Steber, M., O. F. McKenna, H. M. Burlage, A. Taylor, and D. M. Smith. Studies on Toxic Plants for Antibacterial Effects III. Texas J. Sci., 8, 227–234 (1956).

416. Dunn, F. W., J. M. Ravel, and W. Shive. Inhibition Studies with Peptides of Thienylalanine and Phenylalanine. J. Biological Chem., 219, 809–822 (1956).

417. Snell, E. E., and D. E. Metzler. Water-Soluble Vitamins, Part II. Annual Rev. Biochem., 25, 435–462 (1956).

418. Ikawa, M., and E. E. Snell. D-Glutamic Acid and Amino Sugars as Cell Wall Constituents in Lactic Acid Bacteria Biochem. Biophys. Acta, 19, 576–578 (1956).

419. Longenecker, J. B., and E. E. Snell. On the Mechanism and Optical Specificity of Transamination Reactions. Proc. Natl. Acad. Sci., 42, 221–227 (1956).

420. Ham, R. G., and R. E. Eakin. Inhibition of Glyceraldehyde Phosphate Dehydrogenase by Salts other than Lithium Chloride. J. Embryol. Exptl. Morph., 4, 93–95 (1956).

421. Skinner, C. G., T. J. McCord, J. M. Ravel, and W. Shive. O-Carbamyl-L-serine, an Inhibitory Analog of L-Glutamine. J. Am. Chem. Soc., 78, 2412 (1956).

422. Ham, R. G., R. E. Eakin, C. G. Skinner, and W. Shive. Inhibition of Regeneration in Hydra by Certain New 6-(Phenylalkyl)-Aminopurines. J. Am. Chem. Soc., 78, 264 (1956).

423. Skinner, C. O. Inexpensive Micro Vacuum Desiccator. Analytical Chem., 28, 924 (1956). 424. Thomas, R. C., and L. J. Reed. Synthesis of DL-1, 2-Dithiolane-3-caproic Acid and DL-1,

2-Dithiolane-3-butyric Acid, Homologs of alpha-Lipoic Acid. J. Am. Chem. Soc., 78, 6151–6153 (1956).

425. Thomas, R. C., and L. J. Reed. Synthesis of DL-1, 2-Dithiolane-3-butanesulfonamide, an Analog of alpha-Lipoic Acid. J. Am. Chem. Soc., 78, 6150–6151 (1956).

426. Thomas, R. C., and L. J. Reed. Disulfide Polymers of DL-alpha-Lipoic Acid. J. Am. Chem. Soc., 78, 6148–6149 (1956).

427. Williams, R. J. Biochemical Individuality, 1963 (paperback edition), John Wiley & Sons, New York. (Translated into Russian, Italian and Polish.)

428. Estes, J. M., J. M. Ravel, and W. Shive. A Role of Biotin in the Interaction of Ornithine and Carbamyl Phosphate. J. Am. Chem. Soc., 78, 6410 (1956).

429. Pal, P. R., C. G. Skinner, R. L. Dennis, and W. Shive. Cyclopentanealanine and 1-Cyclopentene-l-alanine, Inhibitory Analogs of Leucine and Phenylalanine. J. Am. Chem. Soc., 78, 5116–5118 (1956).

430. Skinner, C. G., W. Shive, R. G. Ham, D. C. Fitzgerald, Jr., and R. E. Eakin. Effects of Some 6-(Substituted)-purines on Regeneration of Hydra. J. Am. Chem. Soc., 78, 5097–5100 (1956).

431. Taylor, A., G. F. McKenna, and H. M. Burlage. Anticancer Activity of Plant Extracts. Texas Rpts. Biol. Med., 14, 538–556 (Winter, 1956).

432. Skinner, C. G., R. G. Ham, D. C. Fitzgerald, Jr., R. E. Eakin, and W. Shive. Synthesis and Biological Activity of Some 6-(Substituted)thiopurines. J. Org. Chem., 21, 1330–1331 (1956).

433. Ifland, P. W., and W. Shive. The Inhibition of Aspartic Acid Utilization in the Synthesis of the Adaptive “Malic Enzyme” in Lactobacillus arabinosus. J. Biol. Chem., 223, 949957 (1957).

434. Skinner, Charles G., J. R. Claybrook, F. D. Talbert, and W. Shive. Stimulation of Seed Germination by 6-(Substituted)thiopurines. Arch. Biochem. Biophys., 65, 567569 (1956).

435. Dunn, F. W., J. M. Ravel, B. F. Mollenhauer, and W. Shive. A Study of Growth Inhibitions by Thienylpyruvic Acid and Related Compounds. J. Biol. Chem., 223, 959–967 (1956).

436. Ham, R. G., D. C. Fitzgerald, Jr., and R. E. Eakin. Effects of lithium ion on regeneration of hydra in a chemically defined environment. J. Exptl. Zool., 133, 559–572 (1956).

437. Huennekens, E. M., S. P. Felton, and E. E. Snell. Lyxoflavin Nucleotides. J. Am. Chem. Soc., 79, 2258–2261 (1957).

438. Longenecker, J. B., and E. E. Snell. Pyridoxal and Metal Ion Catalysis of α β Elimination Reactions of Serine-3-Phosphate and Related Compounds. J. Biol. Chem., 225, 409–417 (1957).

439. Longenecker, J. B., and E. E. Snell. The Comparative Activities of Metal Ions in Promoting Pyridoxal-catalyzed Reactions of Amino Acids. J. Am. Chem. Soc., 79, 142–145 (1957).

440. Skinner, C. G., J. R. Claybrook, F. Talbert, and W. Shive. Effect of 6-(Substituted) Thio- and Amino-Purines on Germination of Lettuce Seed. Plant Physiology, 32, 117–120 (1957).

441. Shaw, W. H. R., and B. Grushkin. The Toxicity of Metal Ions to Aquatic Organisms. Arch. Biochem. Biophys., 67, 447–452 (1957).

442. Ikawa, M., and J. S. O’Barr. Synthesis of Pantoic Acid and Its Congenera by Neurospora. Soc. Exptl. Biol. Med., 94, 334–337 (1957).

443. Kihara, K., and E. E. Snell. The Enzymatic Cleavage of Canavanine to O-Ureidohomo-serine and Ammonia. J. Biol. Chem., 226, 485–495 (1957).

444. Longenecker, J. B., and E. E. Snell. The Comparative Activities of Metal Ions in Promoting Pyridoxal-catalyzed Reactions of Amino Acids, J. Am. Chem. Soc., 79, 142-145 (1957).

445. Rogers, L. L., and R. B. Pelton. Effect of Glutamine on IQ Scores of Mentally Deficient Children. Texas Rpts. Biol. Med., 15, 84–90 (1957).

446. Reed, L. J. The Chemistry and Function of Lipoic Acid. Advances in Enzymology, 18, 319–347 (1957).

447. Skinner, C. G., P. D. Gardner, and W. Shive. Synthesis and Biological Activity of Some 6-(Substituted)-aminopurines. J. Am. Chem. Soc., 79, 2843–2846 (1957).

448. Singer, H., and W. Shive. Synthesis of 7-Nitroindole. J. Org. Chem., 22, 84–85 (1957). 449. Gorton, B. S., and W. Shive. Synthesis of 1-Deazaguanine. J. Am. Chem. Soc., 79, 670–672

(1957). 450. Williams, R. J. Biochemical Genetics and Its Human Implications, Acta genet., 7, 163–175

(1957). 451. Williams, R. J. Normal Young Men, Persp. Biol. Med., l, 97–104 (1957). 452. Williams, R. J. Standard Human Beings versus Standard Values. Science, 126, 453–4

(1957). 453. Williams, R. J. Individuality and Education. Educational Leadership (December, 1957). 454. Williams, R. J. Weight Control as a Biological Process. Nutrition News, 20, (December,

1957). 455. Williams, R. J. Improved Teaching of Chemistry Held Responsibility of All. New York J.

Commerce (September 10, 1957). 456. Williams, R. J. Fiddlers’ Dreams, Chem. & Engr. News, 49, 116–120 (1957). 457. Williams, R. J. Forty Ways to be Dumb. J. Chem. Ed., 34, 261 1957). 458. Williams, R. J. The Importance of Foundation Supported Research in Texas. Conference of

Southwest Foundation Newsletter, 1, 1 (1957). 459. Skinner, C. G., and W. Shive. Effect of Some Isomeric Purine Analogues on Germination of

Lettuce Seed. Plant Physiology, 32, 500–501 (1957). 460. Rogers, L. L., and R. B. Pelton. Effect of Some Glutamine Antagonists on Alcohol

Consumption by Rats. (Presented to Fed. of Am. Societies for Exptl. Biology, April,1957, Chicago, Ill.) Fed. Proc., 16, 238–239 (1957). (ABSTRACT)

461. Ham, R. G., and R. E. Eakin. Use of Hydra for Biochemical Studies on Regeneration. (Presented to Fed. of Am. Societies for Exptl. Biology, April, 1957, Chicago, Ill.) Fed. Proc., 16, 191 (1957). (ABSTRACT)

462. Gorton, B. S., C. G. Skinner, and R. E. Eakin. Activity of Some 6-(Substituted) Purines on the Development of the Moss Tortella caespitosa. Arch. Biochem. Biophys., 66, 493–496 (1957).

463. Reed, L. J. Metabolism and Function of Lipoic Acid. Proc. Int. Symposium on Enzyme Chem.—Tokyo and Kyoto, 71–77 (1957).

464. Rogers, L. L., and R. B. Pelton. Glutamine in the Treatment of Alcoholism. A Preliminary Report. Quarterly J. Studies on Alcohol, 18, 581–587 (1957).

465. Dunri, F. W., J. Humphreys, and W. Shive. Utilization of Tripeptides Arch. Biochem. Biophys., 71, 475–476 (1957).

466. Ravel, J. M., J. M. Estes, B. F. Mollenhauer, and W. Shive. Some Inhibitory Properties of Carbamyl Phosphate J. Biol. Chem., 229, 93–99 (1957).

467. Longenecker, J. B., M. Ikawa, and E. E. Snell. The Cleavage of α-Methylserine and α-Methylolserine by Pyridoxal and Metal Ions. J. Biol. Chem., 226, 663–666 (1957).

468. Fisher, J. R., and R. E. Eakin. Nitrogen Excretion in Developing Chick Embryos. J. Embryol. Exptl. Morph., 5, 215–224 (1957).

469. Gorton, B. S., and R. E. Eakin. Development of the Gametophyte in the Moss Tortella caespitosa. Botanical Gazette, 119, 31–38 (1957).

470. Shive, W., R. N. Snider, B. DuBilier, J. C. Rude, G. E. Clark, Jr., and J. O. Ravel. Glutamine in Treatment of Peptic Ulcer, Texas State J. Med., 53, 840–843 (1957).

471. McCord, T. J., J. M. Ravel, G. G. Skinner, and W. Shive. DL-4-Oxalysine, an Inhibitory Analog of Lysine. J. Am. Chem. Soc., 79, 5693–5696 (1957).

472. Edelson, J., P. R. Pal, G. G. Skinner, and W. Shive. Synthesis of 2-Cyclohexene-1-glycine and 1-Gyclohexene-l-alanine, Inhibitory Amino Acid Analogs. J. Am. Chem. Soc., 79, 5209–5212 (1957).

473. Gawienowski, A. M. The Detection of Iodine-Containing Compounds on Paper Chromatograms. The Analyst, 82, 452–453 (1957).

474. Behal, F. J., and R. E. Eakin. Biochemical Studies of Differentiation in Aspergillus niger. Fed. Proc., 17, 188 (1958).

475. Ham, R. G. Chemically-Induced Loss of Regenerative Capacity in Hydra. Fed. Proc., 17, 236 (1958). (ABSTRACT)

476. Lamford, E. M., Jr., W. M. Harding, and W. Shive. Thymidine Determination by Some Microbiological Assay Methods, Arch. Biochem. Biophys., 73, 180–190 (1958).

477. Lamford, E. M. Jr., G. G. Skinner, and W. Shive. Augmented Inhibition by Kinetin and Related Compounds of Growth of Pteridine-Inhibited Lactobacillus arabinosus, Archives Biochem. Biophys., 73, 191–197 (1958).

478. Skinner, C. G., F. D. Talbert., and W. Shive. Effect of 6-(Substituted) Purines and Gibberellin on the Rate of Seed Germination. Plant Physiology, 33, 190–194 (1958).

479. Ravel, J. M., T. J. McCord, C. O. Skinner, and W. Shive. S-Carbamyl-L-Cysteine, An Inhibitory Amino Acid Analogue. J. Biol. Chem., 232, 159–168 (1958).

480. Edelson, J., J. D. Fissekis, C. G. Skinner, and W. Shive. 3-Cyclohexene-l-glycine, an Isoleucine Antagonist, J. Am. Chem. Soc., 80, 2698–2700 (1958).

481. Ravel, J. M., M. L. Grona, J. S. Humphreys, and W. Shive. Role of Biotin in Carbamylation Reactions. J. Am. Chem. Soc., 80, 2344 (1958).

482. Mefferd, R. B., Jr., W. W. Webster, and M. A. Nyman. Lipid Metabolism in X-Irradiated Mice and Rats. Radiation Res., 8, 461–465 (1958).

483. Mefferd, R. B., Jr., and H. B. Hale. Effects of Thermal Conditioning on Metabolic Responses of Rats to Altitude. Am. J. Physiology, 195, 735–738 (1958).

484. Mefferd, R. B., Jr., M. A. Nyman, and W. W. Webster. Whole Body Lipid Metabolism of Rats After Chronic Exposure to Adverse Environments. Am. J. Physiology, 195, 744–746 (1958).

485. Mefferd, R. B., Jr., and H. B. Hale. Effects of Abrupt Temperature Changes on Excretion Characteristics of Rats Acclimated to Cold, Neutral or Hot Environments. Am. J. Physiology, 195, 726–734 (1958).

486. Hale, H. B., and R. B. Mefferd, Jr. Metabolic Responses to Thermal Stressors of Altitude-Acclimated Rats. Am. J. Physiology, 195, 739–743 (1958).

487. Dalal, U. C., A. Taylor, and G. F. McKenna. The Effect of Plant Extracts on Egg Cultivated Tumor Tissue. Texas Rpts. Biol. Med., 16, 439–442 (1958).

488. Shive, W., and C. G. Skinner. Metabolic Antagonists. Annual Rev. Biochem., 27, 643–678 (1958).

489. Skinner, C. G., J. R. Claybrook, D. L. Ross, and W. Shive. Synthesis of Some alpha- and beta-(6-Purinylthio) carboxylic Acids. 1. Org. Chem., 23, 1223–1224 (1958).

490. Skinner, C. G., G. F. McKenna, T. J. McCord, and W. Shive. Antitumor Activity of Some Amino Acid Analogues. Texas Rpts. Biol. Med., 16, 493–499 (1958).

491. McCord, T. J., J. M. Ravel, C. G. Skinner, and W. Shive. O-Carbazyl-DL-serine, an Inhibitory Analog of Glutamine. J. Am. Chem. Soc., 80, 3762–3764 (1958).

492. Davis, A. L., J. M. Ravel, C. G. Skinner, and W. Shive. The Synthesis and Biological Activity of Some Diamino Acid Analogs. Arch. Biochem. Biophys., 76, 139–147 (1958).

493. Hale, H. B., and R. B. Mefferd, Jr. Factorial Study of Environmentally-Induced Metabolic Changes in Rats. Am. J. Physiology, 194, 469–475 (1958).

494. Mefferd, R. B., Jr., H. B. Hale, and H. H. Martens. Nitrogen and Electrolyte Excretion of Rats Chronically Exposed to Adverse Environments. Am. J. Physiology, 192, 209–218 (1958).

495. Criscuolo, D., H. B. Hale, and R. B. Mefferd, Jr. Oxygen Transport, Utilization and Storage in Rats Acclimated to Altitude at Different Temperatures, 13, 353–356 (1958).

496. Ham, R. G., and R. E. Eakin. Time Sequence of Certain Physiological Events During Regeneration in Hydra. J. Exptl. Zool., 139, 33–54 (1958).

497. Ham, R. G., and R. E. Eakin. Loss of Regenerative Capacity in Hydra Treated with Lipoic Acid. J. Exptl. Zool., 139, 55–68 (1958).

498. McCord, T. J., C. G. Skinner, and W. Shive. Some O-(Substituted Carbamyl) Serines. J. Org. Chem., 23, 1963–1965 (1958).

499. Sund, R. F., J. M. Ravel, and W. Shive. Ornithine-Citrulline Enzyme Synthesis in Biotin-Deficient Cells of Streptococcus Lactis. J. Biol. Chem., 231, 807–811 (1958).

500. Gorton, B. S., J. M. Ravel, and W. Shive. Deazapteridines and Deazapurines Inhibitory Analogues of Folic Acid and Guanine. J. Biol. Chem., 231, 331–338 (1958).

501. Ball, E., J. Humphreys, and W. Shive. Some Antagonisms between Naturally Occurring Amino Acids, Peptides and Keto Acids in Adaptive Enzyme Synthesis and Growth. Arch. Biochem. Biophys., 73, 410–419 (1958).

502. Ifland, P. W., E. Ball, F. W. Dunn, and W. Shive. Peptide and Keto Acid Utilization in Replacing Phenylalanine in Adaptive Enzyme Synthesis. J. Biol. Chem., 230, 897–904 (1958).

503. Skinner, C. G., and W. Shive. Synergistic Effect of Gibberellin and 6-(Substituted)purines on Germination of Lettuce Seed. Arch. Biochem. Biophysics, 74, 283–285 (1958).

504. Williams, R. J. Clinical Implications of Biochemical Differences Between Individuals. Modern Medicine, 26, 134–159 (1958).

505. Williams, R. J. The Improper Study of Mankind. The Texas Quarterly, 1, 16–32 (1958). 506. Williams, R. J. Individuality and Its Significance in Human Life (CHAPTER) In Essays on

Individuality, Felix Morley (ed.) Univ. Penn. Press, Philadelphia, 125–145 (1958). 507. Williams, R. J. Chemical Anthropology—An Open Door. Am. Scientist, 46, 1–23 (1958). 508. Williams, R. J., R. B. Pelton, H-M. Hakkinen, and L. L. Rogers. Identification of Blood

Characteristics Common to Alcoholic Males. Proc. Natl. Acad. Sci., 44, 216–222 (1958). 509. Mefferd, R. B., Jr., E. H. LaBrosse, A. M. Gawienowski, and R. J. Williams. Influence of

Chlorpromazine on Certain Biochemical Variables of Chronic Male Schizophrenics. J. Nervous & Mental Disease, 127, 167–179 (1958).

510. Williams, R. J. Identifying and Treating Potential Alcoholics. J. Criminal Law, Criminology and Police Science, 49, 218–221 (1958).

511. Pelton, R. B., and R. J. Williams. Effect of Panthothenic Acid on Longevity of Mice. Soc. Exptl. Biol. Med., 99, 632–633 (1958).

512. Reed, L. J., M. Koike, M. E. Levitch, and F. R. Leach. Studies on the Nature and Reactions of Protein-Bound Lipoic Acid. J. Biol. Chem., 232, 143–158 (1958).

513. Reed, L. J., F. R. Leach, and M. Koike. Studies on a Lipoic Acid-Activating System. J. Biol. Chem., 232, 123–142 (1958).

514. McKenna, G. F., A. Taylor, and N. Carmichael. Cancer Chemotherapy with Plant Extracts. Texas Rpts. Biol. Med., 16, 203–214 (1958).

515. Rogers, L., and R. B. Pelton. Effect of Behavior-Altering Drugs on Alcohol Consumption by Rats. Texas Rpts. Biol. Med., 16, 133–136 (1958).

516. Shaw, W. H. R. Kinetics of Enzyme Catalyzed Reactions in the Presence of Inhibitors. Chemical Warfare Laboratories Special Publication 3—Report of Symposium LX, (June, 1958).

517. Williams, R. J. Nutritional Insurance With Vitamins: Available But Not Simple. Chem. & Engineering News, 37, 86–89 (1959).

518. Pelton, R. B., R. J. Williams, and L. L. Rogers. Metabolic Characteristics of Alcoholics. I. Response to Glucose Stress Quarterly J. Studies on Alcohol, 20, 28–32 (1959).

519. Skinner, C. G., and W. Shive. Stimulation of Lettuce Seed Germination by 6-(Substituted) Purines. Plant Physiology, 34, 1–3 (1959).

520. Rogers, L. L., and A. M. Gawienowski. Metabolic Characteristics of Alcoholics. II. Serum Copper Concentrations in Alcoholics. Quarterly J. Studies on Alcohol, 20, 33–37 (1959).

521. Koike, M., and L. J. Reed. On the Mechanism of Oxidative Decarboxylation of Pyruvate. J. Am. Chem. Soc., 81, 505 (1959).

522. Reed, L. J., A. C. Schram, and L. E. Loveless. Inhibition of Saccharomyces cerevisiae by p-Aminobenzoic Acid and Its Reversal by the Aromatic Amino Acids. J. Biol. Chem., 234, 904–908 (1959).

523. Nawa, H., W. T. Brady, M. Koike, and L. J. Reed. On the Nature of Protein-Bound Lipoic Acid. J. Am. Chem. Soc., 81, 2908 (1959).

524. Fissekis, J. D., C. G. Skinner, and W. Shive. Synthesis and Biological Activity of Some Cycloalkaneglyoxylic Acids. J. Am. Chem. Soc., 81, 2715–2718 (1959).

525. Ravel, J. M., M. L. Grona, J. S. Humphreys, and W. Shive. Properties and Biotin Content of Purified Preparations of the Ornithine-Citrulline Enzyme of Streptococcus lactis. J. Biol. Chem., 234, 1452–1455 (1959).

526. Leonard, E. O., C. G. Skinner, E. M. Lansford, Jr., and W. Shive. Synthesis and Biological Activity of Some 2-Amino-6-(substituted)-purines. J. Am. Chem. Soc., 81, 907–909 (1959).

527. Edelson, J., C. G. Skinner, and W. Shive. Synthesis and Biological Activity of Some N (Substituted) Glutamines. J. Medicinal and Pharmaceutical Chem., 1, 165–170 (1959).

528. Edelson, J., C. G., Skinner, J. M. Ravel, and W. Shive. 3-Cyclohexene-l-DL-alanine, an Analog of Leucine. Arch. Biochem. Biophys., 80, 416–420 (1959).

529. McKenna, G. F., A. Taylor, and B. S. Gibson. Further Studies of Plant Extracts in Cancer Chemotherapy. Texas Rpts. Biol. Med., 17, 123–133 (1959).

530. Ravel, J., F. Hunter, and W. Shive. The Effect of Proline on Pyrimidine Inhibition of Aspartate Carbamyl Transferase Synthesis. Fed. Proc., 18, 1217 (1959). ABSTRACT.

531. Behal, F. J., and R. E. Eakin. Inhibition of Mold Development by Purine and Pyrimidine Analogs. Arch. Biochem. and Biophys., 82, 439–447 (1959).

532. Behal, F. J., and R. E. Eakin. Metabolic Changes Accompanying the Inhibition of Spore Formation in Aspergillus niger. Arch. Biochem. Biophys., 82, 448–454 (1959).

533. Williams, R. J. Alcoholism: The Nutritional Approach (Book) The University of Texas Press, Austin (1959).

534. Williams, R. J. Individuality of Amino Acid Needs (CHAPTER) in Protein and Amino Acid Nutrition, Anthony A. Albanese (ed.) Academic Press, New York and London, 45–56 (1959).

535. Williams, R. J. Biochemical Individuality and Cellular Nutrition: Prime Factors in Alcoholism. Quarterly J. Studies on Alcohol, 20, 452–463 (1959).

536. Williams, R. J. A Nutritional Approach to Alcoholism. First International Conference on the Alcoholic Beverages Research, June 2–4, 1958, C. Radouco-Thomas (ed.), Pool Finsec S.A., Lausanne, 29–34 (1959).

537. Williams, R. J. The Functioning of Vitamins and Hormones. J. Chem. Ed., 36, 538–539 (1959).

538. Siegel, F. L., and R. J. Williams. The Use of Baby Chicks in Studying Inherent Individuality and its Relationship to Alcoholism. First International Conference on the Alcoholic Beverages Research, June 2–4, 1958, C. Radouco-Thomas (ed.), Pool Finsec S.A., Lausanne, 35–37 (1959).

539. Henderson, R. F., and R. E. Eakin. Alteration of Regeneration in Planaria Treated with Lipoic Acid. J. Exptl. Zool., 141, 175–190 (1959).

540. Ross, D. L., C. G. Skinner, and W. Shive. O-(Substituted)-alpha-amino-beta-hydroxybutyric Acids. J. Org. Chem., 24, 1440–1442 (1959).

541. Fissekis, J. D., C. G. Skinner, and W. Shive. Synthesis of Some Heterocyclic Derivatives of alpha-Keto Acids. J. Org. Chem., 24, 1722–1725 (1959).

542. Ross, D. L., C. G. Skinner, and W. Shive. 2-Amino-2-carboxyethanesulfonamide. J. Org. Chem., 24, 1372–1373 (1959).

543. Ravel, J. M., R. F. Sund, and W. Shive. Protection and Reactivation of Carbamyl Phosphate Synthetase with Sulfate. Biochem. Biophys. Res. Comm., 1, 186–190 (1959).

544. Lansford, E. M., Jr., W. Shive. A Study of the Interactions of Folio Acid Analogues and 6-(Substituted) purines as Growth Inhibitors. J. Medicinal and Pharmaceutical Chem., 1, 245–262 (1959).

545. Edelson, J., C. G. Skinner, J. M. Ravel, and W. Shive. Structural Specificity of Some Amino Acid Antagonists. J. Am. Chem. Soc., 81, 5150–5153 (1959).

546. Ravel, J. M., F. Hunter, and W. Shive. The Effect of Glycine on the Uracil Inhibition of Aspartate Transcarbamylase Synthesis in Escherichia coli W. Biochem. Biophys. Res. Comm., 1, 115–117 (1959).

547. Gilbert, J. B., and Y. Ku. Urinary Excretion of a Ninhydrin-Positive Compound, Probably a Peptide, after Administration of β-Aminoisobutyric Acid to the Mouse. Nature, 186, 160–161 (1960).

548. Fissekis, J. D., C. G. Skinner, and W. Shive. Cycloalkyl Analogs of Pantothenic Acid. J. Am. Chem. Soc., 82, 1654 (1960).

549. Fissekis, J. D., C. G. Skinner, and W. Shive. N-Pantoyl-(Substituted)Amines, Pantothenic Acid Analogues. J. Medicinal and Pharmaceutical Chem., 2, 47–56 (1960).

550. Davis, A. L., C. G. Skinner, and W. Shive. 3-Aminomethylcyclohexaneglycine, a Lysine Analog. Arch. Biochem. Biophys., 87, 88–92 (1960).

551. Nawa, H., W. T. Brady, M. Koike, and L. J. Reed, Studies on the Nature of Protein-bound Lipoic Acid. J. Am. Chem. Soc., 82, 896–903 (1960).

552. Henderson, T. R. Inhibition of Xanthine Oxidase by Kinetin and Kinetin Analogues. Fed. Proc., 19, 314 (March, 1960). ABSTRACT

553. Claybrook, D. L., and R. E. Eakin. A Heat-Inactivated Factor Required for Asexual Growth of Hydra. Fed. Proc., 19, 325 (March, 1960). ABSTRACT

554. Siegel, F. L., and R. J. Williams. Response Patterns to Alcohol in Baby Chicks (ABSTRACT). Fed. Proc., 19, 40 (1960).

555. Reed, L. J. Lipoic Acid (CHAPTER) in The Enzymes, (P. D. Boyer, H. Lardy, and K. Myrback, eds.) 3, Academic Press, New York, 195–223 (1960).

556. Edelson, J., J. Humphreys, and W. Shive. Utilization of Amino Acid Esters by Intact Cells. Texas Rpts. Biol. Med., 18, 596–601 (1960).

557. Fissekis, J. D., C. G. Skinner, and W. Shive. Cycloalkyl Analogs of Pantothenic Acid. J. Am. Chem. Soc., 82, 1654–1656 (1960).

558. Skinner, C. G., and W. Shive. N-Substituted N´-Phenylureas. J. Org. Chem., 25, 2046–2047 (1960).

559. Lansford, E. M., Jr., I. D. Hill, and W. Shive. Reversal by Ribonucleosides of Bacterial Growth Inhibition Caused by Alcohol. J. Biological Chem., 235, 3551–3555 (1960).

560. McDuffie, N. G., Jr., B. S. Gibson, and A. Taylor. Study of Toxic Factors Associated with Mouse Mammary Carcinomas in Egg Cultures. Cancer Res., 20, 1631–1635 (1960).

561. Taylor, A., and N. Carmichael. Toxic Factor Associated with Egg-Cultivated Tumors. Cancer Res., 20, 1636–1639 (1960).

562. Williams, R. J. Why Human Genetics? J. Heredity, 51, 91–98 (1960). 563. Williams, R. J. The Biological Approach to the Study of Personality (Presented to Berkeley

Conf. on Personality Development in Childhood, Univ. of Calif., May 5, 1960.) 564. McKenna, G. F., A. Taylor, and B. S. Gibson. Extracts of Plants and Cancer Chemotherapy.

Texas Rpts. Biol. Med., 18, 233–246 (1960). 565. Rogers, L. L., and A. W. Newton. Serum Electrolytes in Mentally Retarded Children Fed L-

Glutamine. Fed. Proc., 19, 20 (March, 1960) ABSTRACT.

566. Crane, F. L. Quinones in Electron Transport. I. Coenzymatic Activity of Plastoquinone, Coenzyme Q, and Related Natural Quinones. Arch. Biochem. Biophys., 87, 198–202 (1960).

567. Jacobs, E. E., and F. L. Crane. Phosphorylation Coupled to Electron Transport Mediated by Short Chain Derivatives of Coenzyme Q. Biochem. Biophys. Res. Comm., 2, 218–221 (1960).

568. Crane, F. L., and B. Ehrlich. Quinones in Electron Transport. II. Influence of Accessory Lipid Factors on the Activity of Coenzyme Q Analogs. Arch. Biochem. Biophys., 89, 134–138 (1960).

569. Crane, F. L., B. Ehrlich, and L. P. Kegel. Plastoquinone Reduction in Illuminated Chloroplasts. Biochem. Biophys. Res. Comm., 3, 37–40 (1960).

570. Koike, M., L. J. Reed, and W. R. Carroll. α-Keto Acid Dehydrogenation Complexes I. Purification and Properties of Pyruvate and α-Ketoglutarate Dehydrogenation Complexes of Escherichia coli. J. Biol. Chem., 235, 1924–1930 (1960).

571. Koike, M., and L. J. Reed, α-Keto Acid Dehydrogenation Complexes II. The Role of Protein-Bound Lipoic Acid and Flavin Adenine Dinucleotide. J. Biol. Chem., 235, 1931–1938 (1960).

572. Koike, M., P. C. Shah, and L. J. Reed. α-Keto Acid Dehydrogenation Complexes III. Purification and Properties of Dihydrolipoic Dehydrogenase of Escherichia coil, J. Biol. Chem., 235, 1939–1943 (1960).

573. Jacobs, E. E., and F. L. Crane. Uncoupling and Inhibition of Succinate Oxidation by Short Chain Derivatives of Coenzyme Q. Biochem. Biophys. Res. Comm., 3, 333–336 (1960).

574. Shaw, W. H. R. Studies in Biogeochemistry I and II. Geochimica et Cosmochimica Acta, 19, 196–207 (1960).

575. Spangenberg, D. B., and R. G. Ham. The Epidermal Nerve Net of Hydra. J. Exptl. Zool., 143, 195–202 (1960).

576. Henderson, R. F., and R. E. Eakin. Inhibition of Malic Dehydrogenase by Cyclic Disulfides. Biochem. Biophys. Res. Comm., 3, 169–172 (1960).

577. Williams, R. J. Vitamins as Medicinal Agents. J. Chem. Ed., 37, 177 (1960). 578. Gilbert, J. B., Y. Ku, L. L. Rogers, and R. J. Williams. The Increase in Urinary Taurine

after Intraperitoneal Administration of Amino Acids to the Mouse. J. Biological Chem., 235, 1055–1060 (1960).

579. Williams, R. J. Etiological Research in the Light of the Facts of Individuality. Texas Rpts. Biol. Med., 18, 168–185 (1960).

580. Claybrook, D. L., and R. E. Eakin. A Nutritional Requirement for Asexual Reproduction of Hydra. J. Exptl. Zool., 145, 179–190 (1960).

581. Das, M. L., M. Koike, and L. J. Reed. On the Role of Thiamine Pyrophosphate in Oxidative Decarboxylation of α-Keto Acids. Proc. Natl. Acad. Sci., 47, 753–759 (1961).

582. Koike, M., and L. J. Reed. Resolution and Reconstitution of the Escherichia coli Pyruvate Dehydrogenation Complex. J. Biol. Chem., 236, PC33–PC34 (1961).

583. McKenna, G. F., A. Taylor, and C. C. Albers. Essential Oils, Plant Extracts and Chemicals from Plants in Cancer Chemotherapy. Texas Rpts. Biol. Med., 19, 321–326 (1961).

584. Claybrook, J. R., and R. E. Eakin. Effects of Thyroxine on Amphibian Pancreas: Digestive Enzyme Levels and Subcellular Structure in Metamorphosis. Fed. Proc., 20, 206 (1961). ABSTRACT

585. Spangenberg, D. B., and D. L. Claybrook. Infection of Hydra by Microsporidia, J. Protozoology, 8, 151–152 (1961).

586. Hayashi, K., C. G. Skinner, W. Shive. Thioester Analogs as Non-Competitive Metabolic Antagonists. Texas Rpts. Biol. Med., 19, 277–282 (1961).

587. Shive. W. Some Effects of Spermine Related to Deoxyribonucleic Acid. Proceedings of the Robert A. Welch Foundation Conferences on Chemical Research V. Molecular Structure and Biochemical Reactions, Houston, Texas, 221–226, December 4–6 (1961).

588. Williams, R. J. Biochemical Individuality (ARTICLE) in Encyclopedia of Biological Sciences, Peter Gray (ed.) Reinhold Publishing Corp., New York, (1961).

589. Williams, R. J. On Individuality. The Graduate Journal, IV (1), 134–141 (1961). 590. Williams, R. J., and F. L. Siegel. The Physiological Effects of Alcohol in Relation to the

Problem of Alcoholism. Advances in Alcohol and Alcoholic Beverages Research, Gl. Nosal (ed.), Pool Finsec, Geneva, Switzerland, 2, 10–17 (May, 1961).

591. Williams, R. J., and F. L. Siegel. “Propetology,” A New Branch of Medical Science? Am. J. Med., XXXI (3), 325–327 (1961).

592. Williams, R. J. Investigation of Disease Resistance and the Mathematical Problem of Patterns. Proc. Natl. Acad. Sci., 47, 221–224 (1961).

593. Williams, R. J. The Expanding Horizon in Nutrition. Texas Rpts. Biol. Med., 19, 245–258 (1961).

594. Leonard, E. O., C. G. Skinner, and W. Shive. Synthesis of 2-Fluoro-6-benzylaminopurine and Other Purine Derivatives. Arch. Biochem. Biophys., 92, 33–37 (1961).

595. Reed, L. J. Biochemistry of α-Keto Acid Dehydrogenation Complexes. Proceedings of the Robert A. Welch Foundation Conferences on Chemical Research. V. Molecular Structure and Biochemical Reactions, Houston, Texas, 117–127. December 4–6 (1961).

596. Ravel, J. M., J. S. Humphreys, and W. Shive. A Study of Carbamyl Phosphate Synthesis in Streptococcus lactis. Arch. Biochem. Biophys., 92, 525–531 (1961).

597. Skinner, C. G., J. Edelson, and W. Shive. A Conformation of Methionine Essential for its Biological Utilization. J. Am. Chem. Soc., 83, 2281–2285 (1961).

598. Davis, A. L., C. G. Skinner, and W. Shive. The Conformation of Lysine on its Site of Biological Utilization. J. Am. Chem. Soc., 83, 2279–2281 (1961).

599. Ross, D. L., C. G. Skinner, and W. Shive. S-(Alkyl- and Arylcarbamoyl)-L-Cysteines. J. Medicinal & Pharmaceutical Chem., 3, 519–524 (1961).

600. Hayashi, K., C. G. Skinner, and W. Shive. Synthesis and Biological Properties of 4Amino-5-isopropyl-3-isoxazolidone, a Substituted Cycloserine. J. Org. Chem., 26, 1167–1170 (1961).

601. Norton, S. 3, C. G. Skinner, and W. Shive. DL-5-Hydroxy-2-pyridinealanine, a Tyrosine Analog. J. Org. Chem., 26, 1495–1498 (1961).

602. Fradejas, R. G., J. M. Ravel, and W. Shive. The Control of Shikimic Acid Synthesis by Tyrosine and Phenylalanine. Biochem. Biophys. Res. Comm., 5, 320–323 (1961).

603. Shaw, W. H. R., and D. N. Raval. The Inhibition of Urease by Metal Ions at pH 8.9. J. Am. Chem. Soc., 83, 3184–3187 (1961).

604. Siegel, F. L., and M. K. Roach. β-2-Thienyl-DL-alanine, Internal Standard for Automatic Determination of Amino Acids. Analytical Chem., 33, 1628 (1961).

605. Reed, L. J. Lipoic Acid (CHAPTER 36) in Organic Sulfur Compounds, Pergamon Press, London and New York, 443–452, (1961).

606. Taylor, A., and G. F. McKenna. A New Mouse Strain Susceptible to Mammary Cancer. Texas Rpts. Biol. Med., 19, 706–708 (1961).

607. Skinner, C. G., C. Hedgcoth, and D. Wagner. Synergistic Effects on Germination of Mixtures of 6-Benzyl-aminopurine and various Gibberellins. Phyton, 17(2), 141–145, XII-(1961).

608. Skinner, C. G., G. F. McKenna, D. L. Ross, and W. Shive. Antitumor Activity of Amino Acid Analogs. II. S-Methylcarbamoyl-L-Cysteine. Texas Rpts. Biol. Med., 19, 860–865 (1961).

609. Ravel, J. M., B. F. Mollenhauer, and W. Shive. The Indirect Role of Biotin in the Synthesis of Ornithine Transcarbamylase. J. Biol. Chem., 236, 2268–2270 (1961).

610. Maung, M. C., C. G. Skinner, and W. Shive. Biological Activities of Some Homologs of Isoleucine and Valine. Texas Rpts. Biol. Med., 19, 801–810 (1961).

611. Smith, L. C., C. G. Skinner, and W. Shive. Structural Requirements for Phenylalanine Antagonism. Arch. Biochem. Biophys.,, 94, 443–448 (1961).

612. Ross, D. L., C. G. Skinner, and W. Shive. 9-Ribityl Derivatives of Guanine and 8-Aza-guanine. J. Org. Chem., 26, 3582–3583 (1961).

613. Ables, P. G., J. M. Ravel, and W. Shive. The Indirect Role of Biotin in the Synthesis of the Malic Enzyme. J. Biol. Chem., 236, 3263–3266 (1961).

614. Parker, E. D., C. G. Skinner, and W. Shive. Biological Specificities of 4,5-Dehydro Analogues of Isoleucine and Alloisoleucine. J. Biol. Chem., 236, 3267–3271 (1961).

615. Spangenberg, D. B. A Study of Normal and Abnormal Regeneration of Hydra. The Biology of Hydra (Symposium), University of Miami Press, Coral Gables, Fla., 413–423 (1961).

616. Eakin, R. E. Studies on Chemical Inhibition of Regeneration in Hydra. The Biology of Hydra (Symposium), University of Miami Press, Coral Gables, Fla., 399–412 (1961).

617. Henderson, T. R., and R. E. Eakin. Irreversible Alteration of Differentiated Tissues in Planaria by Purine Analogues. J. Exptl. Zool., 146, 253–264 (1961).

618. Spangenberg, D. B., and R. E. Eakin. The Effect of Lipoic Acid on Regeneration of Chlorohydra viridissima. J. Exptl. Zool., 147, 211–218 (1961).

619. Spangenberg, D. B., and R. E. Eakin. A Study of Variation in the Regeneration Capacity of Hydra. J. Exptl. Zool., 147, 259–270 (1961).

620. Henderson, T. R., C. G. Skinner, and R. E. Eakin. Kinetin & Kinetin Analogues as Substrates and Inhibitors of Xanthine Oxidase. Plant Physiology, 37, 552–555 (1962).

621. Koike, M., L. J. Reed, and W. R. Carroll. Molecular Weight and FAD Content of Dihydrolipoic Dehydrogenase from Escherichia coli., 7, 16–17 (1962).

622. Daigo, K., and L. J. Reed. Synthesis and Properties of 2.Acetyl-3,4-dimethylthiazolium Iodide. J. Am. Chem. Soc., 84, 659–662 (1962).

623. Daigo, K., W. T. Brady, and L. J. Reed. Synthesis of Some N-Lipoyl Amino Acids and Peptides. J. Am. Chem. Soc., 84, 662–665 (1962).

624. Reed, L. J. Biochemistry of Lipoic Acid. (Chapter) in Vitamins and Hormones, Vol. 20, Academic Press Inc., New York and London, 1–38 (1962).

625. Gonzalez, E. E., G. F. McKenna, and J. N. Delgado. Anticancer Evaluation of Amphipterygium adstringens. J. Pharmaceutical Sciences, 51, 901–903 (1962).

626. Williams, R. J., Nutrition In A Nutshell, (book) 1962 (paperback); 1963 (hardbound), Doubleday, New York.

627. Williams, R. J., R. B. Pelton, and F. L. Siegel. Individuality as Exhibited by Inbred Animals; Its Implications for Human Behavior. Proc. Natl. Acad. Sci., 48, 1461–1466 (1962).

628. Daigo, K., and L. J. Reed. The Amino Acid Sequence Around the ε-N-Lipoyllysine Residue in α-Keto Acid Dehydrogenation Complexes. J. Am. Chem. Soc., 84, 666–671 (1962).

629. Norton, S. J., J. M. Ravel, and W. Shive. Effect of Deoxyribonucleosides on Deoxyribonucleic acid synthesis in Vitamin B-deficient Lactobacillus leichmanni. Biochim. Biophys. Acta, 55, 222–224 (1962).

630. Norton, S. J., M. C. Maung, C. G. Skinner, and W. Shive. Structural Requirements for Phenylalanine Antagonism III. Some Unsaturated Straight-Chain Amino Acids. Arch. Biochem. Biophys., 96, 287–292 (1962).

631. Segal, H., and C. O. Skinner. Nitrogen Mustard Analog of Thiocytosine J. Org. Chem., 27, 199–201 (1962).

632. McKenna, G. F., and A. Taylor. The Effect of Feeding Chelidonium majus L. on the Incidence of Mammary Tumors in Mice. Texas Rpts. Biol. Med., 20, 64–69 (1962).

633. McKenna, O. F., and A. Taylor. Screening Plant Extracts for Anticancer Activity. Texas Rpts. Biol. Med., 20, 214–220 (1962).

634. Spangenberg, D. B., and R. E. Eakin. Histological Studies of Mechanisms Involved in Hydra Regeneration. J. Exptl. Zool., 151, 85–94 (1962).

635. Conway, T. W., E. M. Lamford, Jr., and W. Shive. A Modified Technique Utilizing Membrane Filtration for the Isolation of Nutritionally-Deficient Bacterial Mutants. Texas Rpts. Biol. Med., 20, 362–365 (1962).

636. Smith, L. G., J. M., Ravel, S. R. Lax, and W. Shive. The Control of 3-Deoxy-D-arabinoheptulosonic Acid 7-Phosphate Synthesis by Phenylalanine and Tyrosine. J. Biol. Chem., 237, 3566–3570 (1962).

637. Ravel, J. M., S. J. Norton, J. S. Humphreys, and W. Shive. Asparagine Biosynthesis in Lactobacillus arabinosus and Its Control by Asparagine through Enzyme Inhibition and Repression. J. Biol. Chem., 237, 2845–2849 (1962).

638. Conway, T. W., E. M. Lamford, Jr., and W. Shive. Purification and Substrate Specificity of a Phenylalanine-activating Enzyme from Escherichia coli 9723. J. Biol. Chem., 237, 2850–2854 (1962).

639. Lamford, E. M., Jr., I. D. Hill, and W. Shive. Effects of Asparagine and Other Related Nutritional Supplements upon Alcohol-Induced Rat Liver Triglyceride Elevation. J. Nutrition, 78, 219–222 (1962).

640. Smith, L. C., J. M. Ravel, C. G. Skinner, and W. Shive. 3,4 Dehydroproline, A Proline Antagonist. Arch. Biochem. Biophys., 99, 60–64 (1962).

641. Leonard, E. O., W. H. Orme-Johnson, T. R. McMurtray, C. G. Skinner, and W. Shive. 2-Hydroxy Derivatives of Some Biologically Active 6-(Substituted) purines. Arch. Biochem. Biophys., 99, 16–24 (1962).

642. Segal, H., C. Hedgcoth, and C. G. Skinner. Synthesis and Biological Activity of Some 4-(Substituted amino) pyrimidines. J. Med. and Pharmaceutical Chem., 5, 871–876 (1962).

643. McDuffie, N. G., Jr. Comparison of Mouse Mammary Tumors Fixed with KMnO4 and with Os04. Virology, 18, 501–503 (1962).

644. Parker, E. D., T. J. Cogdell, J. S. Humphreys, C. G. Skinner, and W. Shive. N-Pantoyl(substituted-phenyl) alkylamines, Inhibitory Analogs of Pantothenic Acid. J. Med. Chem., 6, 73–76 (1963).

645. Shive, W., and C. G. Skinner. Amino Acid Analogues (CHAPTER) in Metabolic Inhibitors, 1 (J. H. Quastel and R. M. Houchster, eds.), Academic Press, Inc., New York, N.Y., 1–73. (1963).

646. Smith, L. C., J. S. Humphreys, C. G. Skinner, and W. Shive, Biological Activities of Some Amino Acid Analogs. III. S-(Substituted-Thiocarbamoyl)-L-Cysteines. Texas Rpts. Biol. Med., 21, 296–301 (1963).

647. Ball, Sister M. I., C. G. Skinner, and W. Shive. Synthesis of Some Carbomoylated Amino Acid Analogs. Texas Rpts. Biol. Med., 21, 168–175 (1963).

648. Norton, S. J., J. M. Ravel, C. Lee, and W. Shive. Purification and Properties of the Aspartyl Ribonucleic Acid Synthetase of Lactobacillus arabinosus. J. Biol. Chem., 238, 269–274 (1963).

649. Gipson, R. M., F. H. Pettit, C. G. Skinner, and W. Shive. Catalytic Hydrogenolysis of Hydroxamic Acids to Amides. J. Org. Chem., 28, 1425– (1963).

650. Ross, D. L., C. G. Skinner, and W. Shive. N-(γ-L-Glutamyl) aminobenzoic Acids. J. Medicinal Chem., 6, 208–209 (1963).

651. Turner, R. B., E. M. Lansford, Jr., J. M. Ravel, and W. Shive. A Metabolic Relationship of Spermine to Folinic Acid and Thymidine. Biochemistry, 2, 163–167 (1963).

652. Smith, L. C., K. Hayashi, J. M. Ravel, C. G. Skinner, and W. Shive. Spermine Reversal of Microbial Growth Inhibition by Thioesters of p-Aminosalicylic Acid. Biochemistry, 2, 159–163 (1963).

653. Conway, T. W., E. M. Lamford, Jr., and W. Shive. Influence of Phenylalanine Analogues Upon Bacterial Accumulation and Incorporation of Phenylalanine. J. Bacteriology, 85, 141–149 (1963).

654. Williams, R. J. Are We Prone to Certain Diseases? Alcalde (February, 1963). 655. Williams, R. J. Key to Health: Your Heredity. Science Digest, 31–39 (April, 1963). 656. Williams, R. J. Pantothenic Acid (CHAPTER) in Comprehensive Biochemistry, M. Florkin

and E. H. Stotz (eds.) Elsevier Publishing Co., Amsterdam, 59–65, (1963). 657. Taylor, A., and N. C. Taylor. Protective Effect of Symphytum officiale on Mice Bearing

Spontaneous and Transplant Tumors. Soc. Exptl. Biol. Med., 114, 772–774 (1963). 658. McDuffie, N. G., Jr. Small Particles Associated with Pox Viruses. J. Bacteriology, 85,

713–715 (1963). 659. Eakin, R. E. An Approach to the Evolution of Metabolism. Proc. Natl. Acad. Sci., 49, 360–

366 (1963). 660. Suzuki, K., and L. J. Reed. Lipoamidase. J. Biol. Chem., 238, 40214025 (1963). 661. Orme-Johnson, W. H., and C. G. Skinner. Paper Chromatography Using Liquid Ion

Exchangers. J. Chromatography, 11, 549–551 (1963). 662. Hedgcoth, C., J. Ravel, and W. Shive. The Separation of the Aspartyl- and Asparaginyl-

RNA Synthetases of Lactobacillus arabinosus. Biochem. Biophys. Res. Comm., 13, 495–499 (1963).

663. Govardham, L. K., and C. G. Skinner. Cyclopentaneglycine (SECTION) in Biochemical Preparations, 10, John Wiley and Sons, Inc., New York, 40–42 (1963).

664. Hedgcoth, C., and C. G. Skinner. β-Hydroxy-DL-Aspartic Acid (SECTION) in Biochemical Preparations, 10, John Wiley and Sons, Inc., New York, 67–72 (1963).

665. McCord, T. J., and C. G. Skinner. O-Carbamoyl-DL-Serine and S-Carbamoyl-L-Cysteine (SECTION) in Biochemical Preparations, 10, John Wiley and Sons, Inc., New York, 18–23 (1963).

666. Koike, M., L. J. Reed, and W. R. Carroll. α-Keto Acid Dehydrogenation Complexes IV. Resolution and Reconstitution of the Escherichia coli Pyruvate Dehydrogenation Complex. J. Biol. Chem., 238, 30–39 (1963).

667. Matthews, J., and L. J. Reed. Purification and Properties of a Dihydrolipoic Dehydrogenase from Spinacia oleracea. J. Biol. Chem., 238, 1869–1876 (1963).

668. Siegel, F. L., and G. Gjerstad. Intermediary Metabolism of Ergot IV. Comparative Amino Acid Metabolism. Planta Medica, 1, 113–118 (1963).

669. Siegel, F. L., M. K. Roach, and W. B. DeVille. Plasma Amino Acid Patterns In Alcoholics: Ethanol Induced Modification. Fed. Proc., 22, 680 (March–April 1963). ABSTRACT.

670. Pettit, F. H., and D. M. Ziegler. The Catalytic Demethylation of N,N-Dimethylaniline-N-Oxide by Liver Microsomes. Biochem. Biophys. Res. Comm., 13, 193–197 (1963).

671. Rogers, L. L., and N. G. Maloney. Uric Acid Excretion in Glutamine-fed Mentally Retarded Children. Proceedings 6th International Congress of Nutrition, Edinburgh, Scotland, (August 9–15, 1963). (ABSTRACT)

672. Siegel, F. L., M. K. Roach, and L. R. Pomeroy. Plasma Amino Acid Patterns in Alcoholism: The Effects of Ethanol Loading. Proc. Natl. Acad. Sci., 51, 606–611 (1964).

673. Siegel, F. L., L. R. Pomeroy, and M. K. Roach. Multiple Discriminant Analysis of Plasma Amino Acid Patterns. Proc. Natl. Acad. Sci., 51, 866–871 (1964).

674. Shive, W. Metabolic Antagonists (CHAPTER) in Symposium on Foods: Proteins and Their Reactions, W. H. Schultz (ed.) The Avi Publishing Company, Inc., Westport, Conn., 389–408 (1964).

675. Orme-Johnson, W. H., J. D. Glass, C. G. Skinner, and W. Shive. Microbial Utilization of Phenylalanyl Peptides. Texas Rpts. Biol. Med., 22, 697–706 (1964).

676. Conway, T. W., E. M. Lansford, Jr., and W. Shive. Inhibition of Bacterial Phenylalanine Utilization and Activation. Arch. Biochem. Biophys., 107, 120–125 (1964).

677. Taylor, A., and N. C. Taylor. The Effect of Sodium Bromide on Tumor Growth. Cancer Res., 24, 751–753 (1964).

678. Ziegler, D. M. and F. H. Pettit. Formation of an Intermediate N-Oxide in the Oxidative Demethylation of N,N-Dimethylaniline Catalyzed by Liver Microsomes. Biochem. Biophys. Res. Comm., 15, 188–193 (1964).

679. Pettit, F. It., W. Orme-Johnson, and D. M. Ziegler. The Requirement for Flavin Adenine Dinucleotide by a Liver Microsomal Oxygenase Catalyzing the Oxidation of Alkylaryl Amines. Biochem. Biophys. Res. Comm., 16, 444–448 (1964).

680. Smith, L. C., J. M. Ravel, S. R. Lax, and W. Shive. The Effects of Phenylalanine and Tyrosine Analogs on the Synthesis and Activity of 3-Deoxy-D-arabino-Heptulosonic Acid 7-Phosphate Synthetases. Arch. Biochem. Biophys., 105, 424–430 (1964).

681. Ravel, J., S-F. Wang, and W. Shive. Separation and Properties of the Glutamyl- and Glutaminyl-tRNA Synthetases of E. coli W. Fed. Proc., 23, 381 (March–April 1964). ABSTRACT

682. Lansford, E. M., Jr., R. B. Turner, C. J. Weathersbee, and W. Shive. Stimulation by Spermine of Tetrahydrofolate Formylase Activity. J. Biol. Chem., 239, 497–501 (7964).

683. Shive, W. Types of Product Regulation of Biological Processes. Sixth International Congress of Biochemistry, New York City, N.Y., (July 26–August 1, 1964). ABSTRACT

684. Fernandez-Moran, H., L. J. Reed, M. Koike, and C. R. Williams. Electron Microscopic and Biochemical Studies of Pyruvate Dehydrogenase Complex of Escherichia coli. Science, 145, 930–932 (1964).

Symposium: Biochemical and Nutritional Aspects of Alcoholism Held in New York, Oct. 2, 1964, under the joint auspices of the Christopher D. Smithers Foundation and the Clayton Foundation Biochemical Institute. Published 93 pages (1965).

685. Williams, R. J. Fundamental Consideration Relating Alcoholism to Biochemistry and Nutrition, 6–16.

686. Shive, W. Glutamine as a General Metabolic Agent Protecting Against Alcohol Poisoning, 17–25. Fincle, L. P., M.D., Staff Physician, Continued Treatment Service, Veterans Administration Hospital, Bedford, Mass., Experiments in Treating Alcoholics with Glutamic Acid and Glutamine, 26–37.

687. Siegel, F. L., Joseph P. Kennedy, Jr., Laboratory, Department of Pediatrics, University of Wisconsin Medical School, Madison, Wis., Plasma Amino Acid Patterns in Alcoholism. (Based on work done at the Clayton Foundation Biochemical Institute. Publ. 672, 673.), 38–58. Parry, A. A., M.D., Chief of Alcoholic Service, Morristown Memorial Hospital, Morristown, New Jersey, Nutrition in the Practical Management of Alcoholics, 59–67. Quastel, J. H., Department of Biochemistry, McGill University, and Director, McGill-Montreal General Hospital Research Institute, Montreal, P.Q., Canada, Effects of Alcohols on Brain Metabolism, 68–81. Vallee, B. L., M.D., Department of Medicine, Harvard Medical School, Boston, Mass., Enzymatic Aspects of Alcoholism, 82–93. Mendelson, J. H., M.D., Department of Psychiatry, Massachusetts General Hospital, Boston, Mass., Discussant. Kety, S., M.D., Chief, Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, Md., Discussant.

688. Mukherjee, B. B., J. Matthews, D. L. Homey, and L. J. Reed. Resolution and Reconstruction of the Escherichia coli α-Ketoglutarate Dehydrogenase Complex. J. Biol. Chem., 240, PC2268–69 (1965).

689. Ravel, J. M., M. N. White, and W. Shive. Activation of Tyrosine Analogs in Relation to Enzyme Repression. Biochem. Biophys. Res. Comm., 20, 352–359 (1965).

690. Ravel, J. M., S-F. Wang, C. Heinemeyer, and W. Shive. Glutamyl and Glutaminyl Ribonucleic Acid Synthetases of Escherichia coli W., J. Biol. Chem., 240, 432–438 (1965).

691. Lloyd, R. F., C. O. Skinner, W. Shive, and R. J. Stedman. α- and γ-Glutamyl Derivatives of Aminobenzoic Acids. J. Medicinal Chem., 8, 398–400 (1965).

692. Taylor, A., and N. C. Taylor. Effects of Sodium Fluoride on Tumor Growth. Soc. Exptl. Biol. Med., 119, 252–255 (1965).

693. Shive, W. Some Effects of Spermine Related to Deoxyribonucleic Acid. Proceedings of The Robert A. Welch Foundation Conferences on Chemical Research, V. Molecular Structure and Biochemical Reactions, December 4–6, 1961, Houston, Texas. (printed in 1965).

694. Gipson, R. M., C. G. Skinner, and W. Shive. Relationship of Structure to Biological Activity of Some Unsaturated Derivatives of Cyclopentaneglycine. Arch. Biochem. Biophys., 111, 2 (1965).

695. Ravel, J. M., J. S. Humphreys, and W. Shive. Control of Glutamine Synthesis in Lactobacillus arabinosus. Arch. Biochem. Biophys., 111, 720–726 (1965).

696. Cox, D. J. Computer Simulation of Sedimentation in the Ultracentrifuge I. Diffusion. Arch. Biochem. Biophysics., 112, 249–258 (1965).

697. Cox, D. J. Computer Simulation of Sedimentation in the Ultracentrifuge II. Concentration-Independent Sedimentation. Arch. Biochem. Biophys., 112, 259–266 (1965).

698. Cox, D. J. and J. Hill. Studies of the Sedimentation Velocity of Ovalbumin in Concentrated Salt Solutions. J. Physical Chem., 69, 3032–3043 (1965).

699. Williams, R. J., and R. B. Pelton. Individuality in Nutrition: Effects of Vitamin A-Deficient and Other Deficient Diets on Experimental Animals. Proc. Natl. Acad. Sci., 55, 126–134 (1966).

700. Reed, L. J., and D. J. Cox. Macromolecular Organization of Enzyme Systems. Ann. Rev. Biochem. (in press) (1966).