Pub. annotated bibliography 1

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Fall Semester 2012-13 Rubric for Assessing Seminar Reflections Roll Book.# 6 Name Juan Enrique Maldonado Weng Date: October 12, 20012 Annotated Bibliography 1: Adamaszek M, Heinrich A. 2010. Anti-Borna Disease virus antibody responses in psychiatric patients: Long-term follow up. Psychiatry and Clinical Neurosciences [Internet]; [Cited 2012 October 12]. DOI:10.1111/j.1440- 1819.2010.02073.x:64:255–261 Available at: http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1819.2010.02073.x/pdf This longitudinal study explores the role of the Borna Disease Virus in psychiatric patients. The investigators used a method called Indirect Immunofluorescence assay (IFA) to prove the presence of BDV in an organism's system. Through this methodology, they measured the amount of antibodies that fought against the virus. From 1985 to 2006, antibody analysis was done on the patients participating in this study. For the experiment, 46 patients were chosen from the major group because they were found to be seropositive for traces of BDV. From this group, the patients with advanced stages of schizophrenia had more traces of antibodies than those in earlier stages. As a result, this can help the scientific community understand that the BDV may be a cause or supporting factor in the formation of schizophrenia. This idea is lead by the fact there has been a presence of the virus in the system. The investigation supports the idea that BDV has a role in the pathogenesis of conditions, and as a result, BDV may contribute to the development of schizophrenic conditions. This group of investigators did an excellent job for collecting data from a large period of time. It also seemed to lack more varied testing of BDV presence, only to have inclined on solely on type of test.

Transcript of Pub. annotated bibliography 1

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Fall Semester 2012-13

Rubric for Assessing Seminar ReflectionsRoll Book.# 6 Name Juan Enrique Maldonado Weng

Date: October 12, 20012

Annotated Bibliography 1:Adamaszek M, Heinrich A. 2010. Anti-Borna Disease virus antibody responses in psychiatric patients: Long-term follow up. Psychiatry and Clinical Neurosciences [Internet]; [Cited 2012 October 12]. DOI:10.1111/j.1440-1819.2010.02073.x:64:255–261 Available at: http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1819.2010.02073.x/pdf

This longitudinal study explores the role of the Borna Disease Virus in psychiatric patients. The investigators used a method called Indirect Immunofluorescence assay (IFA) to prove the presence of BDV in an organism's system. Through this methodology, they measured the amount of antibodies that fought against the virus. From 1985 to 2006, antibody analysis was done on the patients participating in this study. For the experiment, 46 patients were chosen from the major group because they were found to be seropositive for traces of BDV. From this group, the patients with advanced stages of schizophrenia had more traces of antibodies than those in earlier stages. As a result, this can help the scientific community understand that the BDV may be a cause or supporting factor in the formation of schizophrenia. This idea is lead by the fact there has been a presence of the virus in the system. The investigation supports the idea that BDV has a role in the pathogenesis of conditions, and as a result, BDV may contribute to the development of schizophrenic conditions. This group of investigators did an excellent job for collecting data from a large period of time. It also seemed to lack more varied testing of BDV presence, only to have inclined on solely on type of test.

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