PROTEOMICS & PEPTIDE SYNTHESIS...• finding the best analysis/synthesis options for your project...
Transcript of PROTEOMICS & PEPTIDE SYNTHESIS...• finding the best analysis/synthesis options for your project...
PROTEOMICS & PEPTIDE SYNTHESIS CORE
• experimental design and data interpretation• finding the best analysis/synthesis options for your project scope and budget• access to a wide variety of high-quality services from routine to customized
projects in qualitative or quantitative proteomics• N-terminal sequencing and Amino Acid Analysis• quality custom peptide synthesis at discounted prices
Our service commitment is based on quality, reliability and customer satisfaction.
List of ServicesProteomics• Protein Identification • Protein profiling (with and without fractionation) • Localization of posttranslational modifications • Protein mapping/maximum sequence coverage • Protein expression profiling
(Label free quantitation, options ranging from 1hr to 24hr of LC-MS/MS time per sample)• SILAC• TMT/iTRAQ • Quantitation by targeted analysis (parallel reaction monitoring, PRM) • Elucidation of cleavage sites • Sample preparation for a wide variety of samples (including clinical) • Identification of N-terminus by mass spectrometry • Molecular weight measurement of intact proteins
Protein Analysis • N-terminal sequencing (Edman chemistry) • Amino Acid Analysis • old, heavy isotope labeled peptides
Custom Peptide Synthesis • Linear and cyclic peptides • Phosphopeptides and peptides with other posttranslational modifications • Labeled peptides (e.g. fluorophores, biotin, FRET peptides)• Cold, heavy isotope labeled peptides
All projects include consultation, data analysis, interpretation and discussion
Proteomics & Peptide Synthesis Core University of Michigan Medical School
2560A MSRBII 1150 West Medical Center Drive Ann Arbor, MI 48109
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The Proteomics and Peptide Synthesis Core at the University of Michiganprovides access to research services in peptide synthesis, proteomics and proteinanalysis by mass spectrometry and other techniques:
At the Proteomics and Peptide Synthesis Core, we work with each investigator to form an individual plan for project goals and emphasize customization of the experimental design that matches any budget. We provide personalized consultation every step of the way.
–Henriette Remmer, Ph.D., Director, Proteomics & Peptide Synthesis Core
About the BRCFThe BRCF, part of the University of Michigan Medical School Office of Research, is a collection of centralized labs and services offering state-of-the-art instruments, resources and expertise to biomedical researchers, investigators and educators.
For more information on the BRCF, visit research.med.umich.edu/brcf
CONTACT USBIOMEDICAL RESEARCH CORE FACILITIES
University of Michigan Medical School
2570 MSRB II • 1150 W. Medical Center DriveAnn Arbor, MI 48109-0674
Training OpportunitiesThe Proteomics and Peptide Synthesis Core offers sample presentation guides,free project consultation, training seminars and department presentations. For moreinformation, please contact Core Director Henriette Remmer.
Service FeesRequest forms, sample preparation guidelines and a list of service fees are availableonline at: research.med.umich.edu/proteomicscore
Proteomics and Peptide Synthesis Core Henriette Remmer, Ph.D., Core Director
734-763-6285 734-936-2638 [email protected]
research.med.umich.edu/proteomicscore
Open Monday-Friday from 10 a.m. to 4 p.m.