Proteins: Tertiary Structure, Motifs and Fold Classes · 2020. 2. 26. · Proteins: Tertiary...

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Proteins: Tertiary Structure, Motifs and Fold Classes CHEM 430

Transcript of Proteins: Tertiary Structure, Motifs and Fold Classes · 2020. 2. 26. · Proteins: Tertiary...

Page 1: Proteins: Tertiary Structure, Motifs and Fold Classes · 2020. 2. 26. · Proteins: Tertiary Structure, Motifs and Fold Classes CHEM 430. Created Date: 2/27/2017 12:08:13 PM

Proteins: Tertiary Structure, Motifs and Fold Classes

CHEM 430

Page 2: Proteins: Tertiary Structure, Motifs and Fold Classes · 2020. 2. 26. · Proteins: Tertiary Structure, Motifs and Fold Classes CHEM 430. Created Date: 2/27/2017 12:08:13 PM
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Universal Motifs

Universal Motifs

Japanese Design Motifs

Japanese Design Motifs

Secondary and Tertiary Structural Fold Elucidation from 3D ......EM secondary/tertiary structure elucidation algorithms [6]. Depending on the resolution of the 3D Map (in A), our goals

Secondary and Tertiary Structural Fold Elucidation from 3D ......EM secondary/tertiary structure elucidation algorithms [6]. Depending on the resolution of the 3D Map (in A), our goals

FOLD FOLD FOLD FOLD · FRODSHAM, Cheshire, WA6 0DJ FOLD FOLD FOLD FOLD FOLD FOLD FOLD FOLD July 2019 MAXIMUM CONTINUOUS EXPOSURE ... Setting accuracy ±6 ±6 ±14 Switch differential

FOLD FOLD FOLD FOLD · FRODSHAM, Cheshire, WA6 0DJ FOLD FOLD FOLD FOLD FOLD FOLD FOLD FOLD July 2019 MAXIMUM CONTINUOUS EXPOSURE ... Setting accuracy ±6 ±6 ±14 Switch differential

Mutiple Motifs

Mutiple Motifs

Common fold in helix–hairpin–helix proteinsprodata.swmed.edu/Lab/HhH_NAR00.pdf · (HhH) 2 domain. (HhH) 2 is a pseudo-2-fold unit composed of two HhH motifs linked by a connector

Common fold in helix–hairpin–helix proteinsprodata.swmed.edu/Lab/HhH_NAR00.pdf · (HhH) 2 domain. (HhH) 2 is a pseudo-2-fold unit composed of two HhH motifs linked by a connector

Tertiary Motifs in RNA Structure and Folding · 2. RNA Structure 2.1. Elements of RNA Structure RNA structure is divided into three fundamental levels of organization: primary, secondary,

Tertiary Motifs in RNA Structure and Folding · 2. RNA Structure 2.1. Elements of RNA Structure RNA structure is divided into three fundamental levels of organization: primary, secondary,

Modernist Motifs

Modernist Motifs

Vision Motifs

Vision Motifs

RNA Tertiary Structure. Additional Motifs of Tertiary Structure Coaxial helix A minor motif Pseudoknots Tetraloops Loop-loop Ribose zipper Kink turn motif.

RNA Tertiary Structure. Additional Motifs of Tertiary Structure Coaxial helix A minor motif Pseudoknots Tetraloops Loop-loop Ribose zipper Kink turn motif.

Protein Sequence Motifs

Protein Sequence Motifs

Sequence Motifs. Motifs Motifs represent a short common sequence –Regulatory motifs (TF binding sites) –Functional site in proteins (DNA binding motif)

Sequence Motifs. Motifs Motifs represent a short common sequence –Regulatory motifs (TF binding sites) –Functional site in proteins (DNA binding motif)

Tertiary Motifs in RNA Structure and Folding - doudnalab.orgdoudnalab.org/Publications/angchem-38-2327.pdf · formation of the global architecture. c) Representation of the X-ray

Tertiary Motifs in RNA Structure and Folding - doudnalab.orgdoudnalab.org/Publications/angchem-38-2327.pdf · formation of the global architecture. c) Representation of the X-ray

Mini motifs

Mini motifs

Presentation on motifs

Presentation on motifs

Bridgeport - Optimum · FOLD-----FOLD-----FOLD FOLD-----FOLD----- FOLD----- FOLD----- Key Broadcast Basic Optimum Core Optimum Value Optimum Preferred/ Optimum Select Optimum …

Bridgeport - Optimum · FOLD-----FOLD-----FOLD FOLD-----FOLD----- FOLD----- FOLD----- Key Broadcast Basic Optimum Core Optimum Value Optimum Preferred/ Optimum Select Optimum …

Computer practical room€¦ · • Protein structures ... Tertiary structure = 3D fold of one polypeptide chain OmpX (pdb 2M06) Protein(structures:(ter-ary(structure Alpha helices

Computer practical room€¦ · • Protein structures ... Tertiary structure = 3D fold of one polypeptide chain OmpX (pdb 2M06) Protein(structures:(ter-ary(structure Alpha helices

Motifs & Accessories

Motifs & Accessories

Carnegie Mellon School of Computer Science 1 Protein Tertiary and Quaternary Fold Recognition: A ML Approach Jaime Carbonell Joint work with: Yan Liu(

Carnegie Mellon School of Computer Science 1 Protein Tertiary and Quaternary Fold Recognition: A ML Approach Jaime Carbonell Joint work with: Yan Liu(

Motifs Ch1

Motifs Ch1