ACADEMIC SENATE: SAN DIEGO DIVISION, 0002 UCSD, LA JOLLA, CA 92093-0002

(858) 534-3640 FAX (858) 534-4528

January 19, 2017 PROFESSOR ANDREW McCULLOCH, Director Interdisciplinary PhD Specialization in Multi-Scale Biology PROFESSOR JOSEPH WANG, Chair Department of NanoEngineering SUBJECT: Proposal to establish PhD degrees in Chemical Engineering and NanoEngineering with a

Specialization in Multi-Scale Biology At its January 9, 2017 meeting, the Graduate Council approved the proposal to establish the PhD specialization in Multi-Scale Biology in the NanoEngineering and Chemical Engineering PhD programs. The Graduate Council will request that the proposal be placed on the January 31, 2017 Representative Assembly agenda for final approval. If the proposal is approved by the Representative Assembly, the 2017-18 General Catalog will include the proposed catalog copy for the PhD Specialization in Multi-Scale Biology in the graduate section for the Department of NanoEngineering.

Sincerely, Richard Arneson, Chair Graduate Council

cc: F. Ackerman M. Allen S. Cassedy

R. Rodriguez K. Roy J. Talbot

TELEPHONE (858) 534-2547 FAX (858) 332-1706

EMAIL: amcculloch@ucsd.edu

ANDREW D. McCULLOCH, Ph.D. PROFESSOR OF BIOENGINEERING AND MEDICINIE JACOBS SCHOOL DISTINGUISHED SCHOLAR DEPARTMENT OF BIOENGINEERING POWELL-FOCHT BIOENGINEERING HALL (PFBH) ROOM 233 9500 GILMAN DRIVE, LA JOLLA, CA 92093-0412

December 5, 2016

Memo to: Richard Arneson, Chair Graduate Council

From: Andrew McCulloch, Director Interdisciplinary Ph.D. Specialization in Multi-Scale Biology Professor of Bioengineering and Medicine

Subject: Addition of NanoEngineering and Chemical Engineering Ph.D. Programs to the Interdisciplinary Ph.D. Specialization in Multi-Scale Biology

I am writing to request that the NanoEngineering Ph.D. Program, and the Chemical Engineering Ph.D. Program (within the NanoEngineering Graduate Programs), be added as participating programs in the Multi-Scale Biology Specialization. Approval of this proposal allows this UCSD Specialization to grow from the current eight participating departments and graduate programs to ten. NanoEngineering Ph.D. students currently participate informally in the specialization events and interdisciplinary lab courses. At the Annual Steering Committee Review meeting in June, the committee reviewed the application of a Chemical Engineering predoctoral student to participate in the Specialization. Discussion then followed on the proposal to add NanoEngineering Department Ph.D. program(s), including Chemical Engineering, to the specialization, with unanimous agreement to submit to Graduate Council.

Attached please find the support letter from Professor Joseph Wang, SAIC Endowed Chair with NanoEngineering, declaring support to add this optional specialization to their Ph.D. programs and agreeing to accommodate the requirements of the specialization for participating students in the Chemical Engineering. The NanoEngineering PhD programs fit very well with the aims of the specialization and already have faculty participating in the training program. Professors Guarav Arya, Adah Almutairi, Karen Christman, Mike Heller, and Michael Sailor are all participating faculty in the Specialization.

The approval of NanoEngineering and Chemical Engineering Ph.D. programs to offer this degree specialization will enhance the goal of the interdisciplinary specialization. This interdisciplinary specialization brings together graduate students and faculty from a wide range of different disciplines with a common interest in quantitative approaches to problems in biology that span physical scales of biological organization. Students participating in the specialization have unique opportunities in developing a variety of specialized technologies for measuring, manipulating and analyzing biological structures at a range of scales from the single molecule to the whole organism.

We recently renewed our NIH T32 Training Grant for an additional five years, and we have an excellent record of student graduation, recruitment and retention of under-represented minorities and women, and of promoting new interdisciplinary interactions between students and faculty within and beyond the current eight different departments and four divisions. Currently students come from eight other graduate programs from Engineering, Physical Sciences, Biological Sciences and Health Sciences.

If you have any further questions on the proposed specialization please contact me directly. Sincerely,

Andrew McCulloch, Ph.D. Distinguished Professor of Bioengineering and Medicine Director, Interfaces Graduate Training Program cc: Mark Ellisman, Co-Director Professor, Neurosciences Terrance Sejnowski, Co-Director Professor, Neurobiology Susan Taylor, Co-Director Professor, Chemistry and Biochemistry

Proposal to Include NanoEngineering and Chemical Engineering as Participating Ph.D. Programs in the UCSD Ph.D.

Specialization in Multi-Scale Biology

Executive Summary The approval of this change in the existing Ph.D. Specialization in “Multi-scale Biology” allows NanoEngineering Department and the Chemical Engineering Ph.D. program (housed within the NanoEngineering Department) to offer this degree specialization. This will enhance the goal of the interdisciplinary specialization to bring together graduate students and faculty from a wide range of different disciplines with a common interest in quantitative approaches to challenges in biology that span physical scales of biological organization and require a variety of specialized technologies for measuring, manipulating and analyzing biological structures at a range of scales from the single molecule to the whole organism.

The Ph.D. Specialization in Multiscale Biology, approved in 2009, provides a unique interdisciplinary education at the interfaces between the biological, medical, physical and engineering sciences. The eight currently participating programs are: Bioengineering, Biological Sciences, Biomedical Sciences, Chemistry and Biochemistry, and Materials Science and Engineering, Mechanical and Aerospace Engineering, Neurosciences, and Physics. The specific objectives of this program are:

1. To train a new generation of cross-disciplinary scientist who has been actively engaged in life science research and training activities at the interfaces between more than two established scientific disciplines via a formal collaboration.

2. To provide state-of-the-art training in specialized research technologies through a hands-on graduate laboratory course curriculum co-taught by faculty and to students from more than one participating department or graduate program.

3. To provide a unique educational focus aimed at integrative and quantitative analysis across multiple scales of biological organization from molecule to organism in health and disease.

The motivation for proposing this change, adding a ninth and tenth participating program, is to provide NanoEngineering Ph.D. and Chemical Engineering Ph.D. students with these specialized interdisciplinary research opportunities and formal recognition on their degrees for the specialization course and other requirements met.

Graduate Student Support Students in the specialization are supported through the home departments and subject to support policies within. Additionally, students may be eligible for T32 training grant funding during the 2nd year of their Ph.D. program, and for a two-year tenure. We recently renewed our NIH T32 Training Grant for another five years, and we have an excellent record of student graduation, recruitment and retention of under-represented minorities and women, and of promoting new interdisciplinary interactions between students and faculty within and beyond the current eight different departments and four divisions.

Students in the participating programs of the specializations also may apply for the match commitment offered through the Dean of Graduate Division, The San Diego Fellowship Match Commitment. The specialization receives two Fellowship Match Commitment awards, each provide $28,000 in stipend, tuition and fees to a student in a participating program.

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Teaching Requirement Residency Requirement This proposed change does not change the existing requirement.

The Ph.D. specialization includes one quarter of half-time (10 hours per week) service as a TA (in the third or fourth year) for academic teaching credit in one of the six lab courses that the student has already taken in a previous year. Faculty instructors complete formal evaluations and assign non-letter grades for the two TAs assigned to each lab course

Program of Study This proposed change does not change the existing requirement.

The Ph.D. Specialization in Multi-Scale Biology Program at UCSD consists of a 4-5 year home program-based Ph.D. specialization. The structure of the Ph.D. component is described below. The Ph.D. component is designed to allow a student to obtain standard basic training in their chosen field within the Biological Sciences, Physical Sciences, Engineering and Health Sciences with training in integrative and quantitative analysis across multiple scales of biological organization from molecule to organism in health and disease into their graduate studies. Requirements consist of the home program requirements and graduate lab course requirements that form the specialization. Their first year of study includes preparatory lecture courses to satisfy the core curriculum requirements of the home degree program. Students admitted to the Specialization program are required to take at least three of the new graduate laboratory courses, typically taken during the first and/or second year.

Course Requirements Graduate Laboratory Courses

This proposed change does not change the existing requirement (complete 3 courses from selection of "electives" with lab components).

1. BENG283/CHEM283/BIOM283Supramolecular Complex Characterization2. BENG276/CHEM276/MATH276Numerical Analysis for Multi-Scale Biology3. NEU260/CHEM260Light and Electron Microscopy of Cells and Tissues4. BENG278Magnetic Resonance Imaging5. PHY 245/BGGN 265Optical Imaging of Structure and Function in Excitable Systems6. BENG 277/BIOM 287Tissue Engineering7. BENG 260/BGGN 260Multi-Scale Neurodynamics8. BENG 235Molecular Imaging and Quantitation in Living Cells

Co-Advisors This proposed change does not change the existing requirement.

During the Spring Quarter, prospective specialization students submit a proposal that describes their research interests, planned course of lab study in the second year, proposed research co-mentors and the relationship between their research interests and the curriculum of the

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specialization. Students formally join the specialization at the end of the first year. In reviewing applications for admission, the Steering Committee takes into account demand for laboratory course slots, the relevance of the program theme to the student’s research interests, the participation of their proposed co-advisors in the program, and the ideal of balancing the distribution of specialization students from across the participating graduate programs.

Application to the Program This proposed change does not change the existing requirement.

The Steering Committee reviews written applications for admission to the proposed degree specialization from students already admitted to one of the participating home degree programs. In order to assist with recruitment of students, we advertise it to prospective graduate students and invite interested students who were admitted to each of the participating programs to attend an Information Session. Additionally, we have home departments advertise the availability of this new specialization through home website announcements and through the Graduate Interfaces Training Program website (interfaces.ucsd.edu).

Program Administration This proposed change does not change the existing requirement.

The specialization is managed from the Department of Bioengineering. The department currently administers the Graduate Interfaces Training Program and it has been very successful in implementing the goals, including course development administration and student-faculty events. Academic leadership of the program has involved faculty with appointments in all four participating divisions. The Program Directors work with a Steering Committee consisting of Co-Program Directors and the instructors of the seven laboratory courses.

The Steering Committee meets quarterly to review progress and educational effectiveness, budgets, enrollments and applications to join the specialization and to plan events and coordinate with participating graduate programs. As necessary, the committee prioritizes requests for enrollment in specific lab courses if they are over-subscribed in a given year.

Faculty membership is approved and reviewed by each of the participating programs who are also supporting the program.

Basis for the Change There are several compelling reasons why a specialization is a necessity for NanoEngineering and Chemical Engineering:

1. NanoEngineering/Chemical Engineering students have been attending the Specializationevents and lab courses, indicating support for the unique interdisciplinary researchtraining afforded through the specialization curriculum and cross-disciplinary events.

2. Dual mentorship is a required component of the specialization and has been a successfuland proven model for interdisciplinary training at UCSD since the 2009 approval of thisspecialization. Adding NanoEngineering/Chemical Engineering to the specializationprovides a means to promote new collaborations between diverse interdisciplinary groupsof faculty.

3. Graduate students of the NanoEngineering/Chemical Engineering program currentlyparticipate informally in the specialization events and interdisciplinary lab courses. We

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have discussed the possibility of NanoEngineering Department, including Chemical Engineering, joining the specialization before and the responses from faculty have been supportive. The matter is starting to take on greater urgency, as participation in interdisciplinary doctoral degree specializations becomes official for students when they advance to candidacy. Therefore, students face the prospect of not receiving recognition on their degree for the specialization course and other requirements met to date.

History of the Existing Programs and Proposal for the Future 2005-06

• UCSD awarded one of ten Interfaces Graduate Training Program Grants entitled“Multiscale Analysis of Biology Structure and Function” from the Howard HughesMedical Institute (HHMI) totaling $1,000,000. The award start date was January 1st,2006. There has only been one competition.

• Six hands-on graduate laboratory course curricula developed by interdisciplinary teamsof faculty members

• 20 Graduate student affiliates who have signed up and participated in program via courseenrollment, TA appointments, student-student and student-faculty events.

2006-07 • Five graduate laboratory courses offered through-out academic year.• Faculty-Student Lecture Dinner, Topics of Interest, February 22, 2007• 1st Annual Interfaces Graduate Student Symposium, June 15th, 2007• 38 Graduate student affiliates

2007-08 • Five laboratory courses offered and sixth course developed• 1st Annual Interfaces Student-Faculty Retreat, April 25th, 2008• Spring 2008 - Submit Ph.D. specialization proposal for Campus review and approval• 2nd Annual Interfaces Graduate Student Symposium scheduled for June 13th, 2008• Submit T32 Training Grant proposal to NIH by June 17th, 2008.• 49 Graduate student affiliates

2009-13 • Upon formal approval, invite continuing student affiliates from participating degree

programs to enter the specialization.• Spring/Summer 2009 - present – New students accepted into the Specialization.

2013-present • Renewal of NIH NIBIB training grant for additional five years with six fellowship

appointments available to students of participating programs.• Summer 2015, Material Sciences Specialization approved by Graduate Council

Representative Assembly.• Summer 2016, Program Director and Trainees accepted presentation participation at NIH

Grantees Meeting, Bethesda, Maryland• The Program, in it’s 10th year, held the Annual Graduate Student Research Symposium.

This event is planned by the trainees, and includes keynote speaker(s), student research“quick talks”, poster presentations, as well as a popular career panel discussion withinvited speakers in various career stages and paths in life sciences.

Institutional Support Commitment The financial plan involves cost-sharing between the planned NIH training grant, the participating Deans, the VC Research and the SVCAA for the annual laboratory operating costs of $80,000. Academic Affairs all renewed their financial commitment to this program (which supports the laboratory-based curriculum) and have actually increased it from $250,000 to $350,000 because of the key role we play in promote new interdisciplinary education and collaborations in Quantitative Biosciences, a major new campus initiative. Note that in addition, all faculty instructors contribute to this curriculum as part of their regular teaching loads and no funds for teaching salaries are need. Graduate Studies Dean Barrett has committed to the aims of URM recruitment by providing two matching Diversity Fellowships per year for the duration of the proposed renewed training grant. This commitment is currently valued at $56,000 per year (two fellowships opportunities for participating program students). The Dean of Physical Sciences, the Dean of Biological Sciences, the Dean of Engineering and the Executive Vice Chancellor of Academic Affairs have pledged $250,000 over the five years of this award to support and sustain it. In addition, the Vice Chancellor for Health Sciences has committed an additional $100,000 for a total of $350,000. The Chair of Radiology has committed instrument-matching time for the MRI lab currently worth $10,000 per year. Augmenting this annual total with a portion of trainee-related expenses (not exceeding $4,200 per trainee) from the proposed T32 will ensure that the additional expenses of the unique lab-based curriculum will be fully covered while allowing for expansion and innovation of the curriculum. The Department of Bioengineering provides full-time administrative support to the Multi-Scale Biology specialization. All divisions have committed space and laboratory facilities for the execution of the curriculum.

Program Overview The Ph.D. specialization in Multi-Scale Biology at UCSD leverages on the strength of the participating departments/programs within the Biological Sciences, Physical Sciences, Engineering and Health Sciences by being home-department based rather than a stand-alone program.

Catalog Copy Proposed Catalog is attached as pdf document “Catalog Copy”.

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Prof. Andrew McCulloch Department of Bioengineering University of California, San Diego 9500 Gilman Drive La Jolla, CA 92093-0412 (e-mail) amcculloch@ucsd.edu (Tel) 858-534-2547

Dear Prof. McCulloch,

November 30, 2016

I am writing to express the support of adopting the degree specialization in “Multi-Scale Biology” for students in the NanoEngineering and Chemical Engineering Ph.D. Programs.

The NanoEngineering Department, including the Chemical Engineering Program, approves of the aims and objectives of this degree specialization which will train a cadre of Ph.D. scientists at the interface between Biological Sciences, Physical Sciences, Engineering and Health Sciences. UC San Diego educational divisions including the Jacobs School of Engineering, and the NanoEngineering Department, realize the importance of interdisciplinary education and support such broader-scoped educational efforts. The NanoEngineering and Chemical Engineering Ph.D. Programs currently have more than 106 graduate students with their thesis topics covering a quite broad, interdisciplinary spectrum of science and engineering, including physics, chemistry, biology, medicine, and various disciplines of engineering such as bioengineering, mechanical engineering, nanoengineering, chemical, electrical and structural engineering.

The faculty members advising our Ph.D. engineering students (38 participating faculty members at UCSD) and many graduate students will benefit from the proposed Multiscale Biology specialization, as this degree specialization will enhance the multi-disciplinary aspects of education, in particular to those students in the fields of biological science and engineering.

The NanoEngineering Department has already committed to educational efforts in the biomaterials aspects and bio-inspired materials design/fabrication aspects, with a designated graduate course in our curriculum to be taught every year.

On Specific Elements of the specialization, the NanoEngineering Ph.D. and Chemical Engineering Ph.D. Programs:

• Approves on specific elements of the specialization of academic requirements outlined in the proposed specialization.

• Confirms elective course credit towards degree requirements. • Confirms that students in our program will have full access to the proposed degree

specialization. • Confirms our commitment of first year financial support of excellent newly-admitted

NanoEngineering and Chemical Engineering students with interests in the biomaterials and biological engineering/science area in their first year via the support policy of offering one-year, Engineering fellowship.

• While the NanoEngineering and Chemical Engineering Program does/does not have its own TA assignments from UCSD, top ranked students often are able to secure TA opportunities through standard TA application procedures.

• Agrees that advising, thesis committee, thesis proposal and faculty membership policies are consistent with program policy.

• Will advertise this Ph.D. Specialization in Multiscale Biology to prospective and new students.

• Will encourage faculty participation in program events and teaching. • Will continue to contribute to Interfaces teaching and events.

We are confident that the support and commitments from our NanoEngineering and Chemical Engineering Programs will enable the campus approval and provide specialized training to our students.

Sincerely yours,

Dr. Joseph Wang Chair and Distinguished Professor Department of NanoEngineering

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

NanoEngineering (NANO) [ undergraduate program | courses | faculty ]

BUSINESS AFFAIRS: 240A Structural Materials Engineering Building, Warren College STUDENT AFFAIRS: Undergraduate Affairs: 241A Structural Materials Engineering Building, Warren College Graduate Affairs: 240A Structural Materials Engineering Building, Warren College http://nanoengineering.ucsd.edu

All courses, faculty listings, and curricular and degree requirements described herein are subject to change or deletion without notice. Updates may be found on the Academic Senate website: http://senate.ucsd.edu/catalog-copy/approved-updates/.

Graduate Program

Degree and Program Options

The NanoEngineering Program offers graduate instruction leading to the MS and PhD in NanoEngineering; and PhD in NanoEngineering with a Specialization in Multi-scale Biology.

The Chemical Engineering Program offers graduate instruction leading to the MS and PhD in Chemical Engineering; and PhD in Chemical Engineering with a Specialization in Multi-scale Biology.

NanoEngineering Program (NANO)

Program Objectives

The Department of NanoEngineering (NE) now offers the MS and PhD in NanoEngineering with a new, unique curriculum centered on our strong research position in nano-biomedical engineering and nanomaterials synthesis and characterization activities. The NanoEngineering Graduate Program provides a course of study for both the MS and PhD, with a focus on underlying scientific, technical, and engineering challenges for advancing nanotechnology in the controlled synthesis of nanostructured materials, especially for biomedical, energy, and environmentally related technologies. Our graduate degree program is uniquely designed to educate students with a highly interdisciplinary curriculum, focusing on core scientific fundamentals, but extending the application of that fundamental understanding to complex problems requiring the ability to integrate across traditional science and engineering boundaries. Specific courses in our core cluster address both the fundamental science and the integration of this science into engineering problem solving. Three main educational paths within the single degree title ‘NanoEngineering’ are proposed:

• Biomedical Nanotechnology • Molecular and Nanomaterials • Nanotechnologies for Energy and the Environment

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

The new NanoEngineering curriculum has the following objectives:

• Prepare students for nanotechnology by providing them with a sound grounding in multidisciplinary areas of nanoscience and nanoengineering

• Increase students' understanding of materials and their properties at the atomic and nanometer level, including an understanding of the intimate relationship between material scale (nanostructure) and the properties/functionality of materials

• Prepare graduates who, while skilled in areas of nanoscience and nanoengineering, will be qualified for jobs in traditional science-based industries and government laboratories and, as the nanotechnologies emerge and mature, will be positioned for jobs in these applied areas. This program will be anticipating trends and providing students with integrated, cross-disciplinary scientific knowledge and professional skills

• Educate a new generation of engineers who can participate in, and indeed seed, new high-technology companies that will be the key to maintaining jobs, wealth and educational infrastructures as nanotechnology results in a new industrial revolution

• Enable the students to develop a range of professional, scientific, and computational skills that will enhance employment opportunities in a wide range of industrial and governmental institutions

• Prepare students for the workplace through developing their ability to contribute constructively to multidisciplinary teams, learn team engineering principles and methods, to communicate both orally and in written form, and to be familiar with modern, computer-based communication technology. This will be achieved using nontraditional education techniques including group-based problem-based learning, flexible delivery and web-based interactive tutorials.

In NanoEngineering, we design and manufacture devices and systems that exploit the unique properties of nanoscale materials to create entirely new functionality and capabilities. Due to the scale of engineering involved, the field of NanoEngineering is inherently interdisciplinary that often utilizes biochemical processes to create nanoscale materials designed to interact with synthetic inorganic materials. The curriculum is built to address the educational needs of this new engineering field.

NanoEngineering BS/MS Contiguous Program

A contiguous terminal program leading to a bachelor of science and master of science degree in NanoEngineering is offered to a student with junior standing who has an overall UC San Diego GPA of 3.0 and a 3.5 GPA in upper-division courses in the major. Students must apply for admission to the program during the last quarter of their junior year (more specifically, the fourth quarter prior to the receipt of the BS). Details of the program are available from the Department of NanoEngineering Graduate Student Affairs Office.

The MS program is intended to extend and broaden an undergraduate background and/or equip practicing engineers with fundamental knowledge in their particular fields. The degree is offered under both the Plan I, Thesis Plan, or Plan II, Comprehensive Examination Plan.

Graduate Program

The NanoEngineering Program offers graduate instruction leading to the MS and PhD in NanoEngineering.

Admission is in accordance with the general requirements of the Graduate Division, which requires at least a BS in some branch of engineering, sciences, or mathematics; an overall GPA of 3.0, and three letters of recommendation from individuals who can attest to the academic or professional competence and to the depth of their interest in pursuing graduate study. Students who have already received a prior MS in a similar field will not be admitted to the program.

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

In addition, all applicants are required to submit GRE General Test Scores. A minimum score of 550 on the Test of English as a Foreign Language (TOEFL) is required of all international applicants whose native language is not English. Students who score below 600 on the TOEFL are strongly encouraged to enroll in an English as a second language program before beginning graduate work. UC San Diego Extension offers an excellent English language program during the summers as well as the academic year.

Applicants are judged competitively. Based on the candidate’s background, qualifications, and goals, admission to the program is in one of three categories: MS only, MS, or PhD. Admission to the MS only category is reserved for students for whom the MS is likely to be the terminal graduate degree. The MS designation is reserved for students currently interested in obtaining an MS but who at a later time may wish to continue in the doctoral degree program. Admission to the PhD program is reserved for qualified students whose final aim is a doctoral degree.

Nonmatriculated students are welcome to seek enrollment in graduate-level courses via UC Extension’s concurrent registration program, but an Extension student’s enrollment in a graduate course must be approved by the instructor.

Master’s Degree Program

The program offers the MS in NanoEngineering under both the Thesis (Plan I) and the Comprehensive Examination (Plan II); see “Graduate Admission: Master’s Degrees.” The requirements for the MS degree are as follows:

1. All students must complete a total of thirty-six units. 2. All students must complete five mandatory core courses (NANO 201, 202, 203, 204, 205) and one course

from any focus area selected from an approved list of graduate courses with the consent of a faculty adviser. Enrollment in NANO 200, as required. See “Courses” for descriptions.

3. Students either complete a thesis (Plan I) or pass a comprehensive examination (Plan II) as described in the “Graduate Admission: Programs of Study” section of this catalog.

4. Students must meet all other requirements established by the university.

The three focus areas and related courses are Focus 1 – Biomedical Nanotechnology: NANO 210, 241, 242, 243, 244, 247A, 247B, 247C, 262 Focus 2 – Molecular and Nanomaterials: NANO 227, 230, 234, 239, 241, 242, 250, 251A, 251B, 252, 253, 263, 264, 265 Focus 3 – Nanotechnologies for Energy and the Environment: NANO 212, 241, 245, 255, 257, 258, 259, 260, 261, 266

Students who transfer with some graduate credit or an MS from another institution will have their records reviewed by a faculty adviser, and an appropriate individual course of study may be approved. The MS program is intended to extend and broaden an undergraduate education with fundamental knowledge in different fields. The degree may be terminal, or obtained on the way to the PhD. The degree is offered under both the Thesis Plan I and the Comprehensive Examination Plan II.

MS Time Limit Policy: Full-time MS students are permitted seven quarters in which to complete all requirements. While there is no written time limit for part-time students, the department has the right to intervene and set individual deadlines if it becomes necessary.

Course requirements: All MS students must complete a total of thirty-six units, which include a core of five courses (twenty units).

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

No more than a total of eight units of NANO 296 and 298 may be applied toward the course work requirement. Units in seminars (NANO 200 and 279) may not be applied toward the degree requirement.

Thesis Plan I: Completion of the research thesis (NANO 299) fulfills twelve units toward the total graduation requirement. The balance is made up of the five core courses (twenty units) and one additional elective course (four units) subject to the restrictions described above.

Comprehensive Examination Plan II: This plan involves course work only and culminates in an oral comprehensive examination based on topics selected from the core courses. In addition to the five core courses (twenty units), one must choose an additional four electives (sixteen units) subject to the restrictions of NANO 279, 296, and 298 described above. A student should consult their academic adviser to choose an appropriate course schedule.

A sample program is shown:

Fall Winter Spring NANO 201 NANO 203 NE Elective NANO 202 NANO 204 NE Elective NE Elective NANO 205 NE Elective

Change of Degree: Upon completion of the requirements for the MS, students admitted as MS only or MS candidates are not automatically eligible for admission to the PhD program. MS-only and MS candidates who subsequently wish to pursue a doctorate must submit an application for a change in status to their examining committee. The application, if approved by the committee, must be signed by a faculty member who expects to serve as the student’s PhD adviser. The student must also submit a General Petition for graduate students to effect the change of status. If the student elects the comprehensive examination plan for the MS, the examining committee may recommend that the comprehensive examination replace the preliminary qualifying examination expected of PhD students, but must be passed at the 70 percent grade.

Doctoral Degree Program

The PhD program is intended to prepare students for a variety of careers in research and teaching. The emphasis is on research. All students, in consultation with their advisers, develop appropriate course programs that will prepare them for the Preliminary Qualifying Examination and for their dissertation research. These programs must be planned to meet the time limits established to advance to candidacy and to complete the requirements of the degree. A PhD in NanoEngineering requires the selection of a specific focus (Biomedical Nanotechnology, Molecular and Nanomaterials, or Nanotechnologies for Energy and the Environment), and consists of the successful completion of ten courses: the five required core courses, three electives from the student’s selected focus, and two electives from any of the two remaining focuses, the ENG-10X courses (for team engineering, leadership, and entrepreneur skills) or from an approved list of electives from other departments across campus, with adviser’s consent. While only one degree title is offered—NanoEngineering—the choice of a specific focus area is to ensure that the graduate student curriculum is both tailored to their interest and sufficiently in-depth to ensure a complete understanding of their field of interest.

After completing the MS degree (or meeting equivalent requirements) and meeting the minimum standard on the comprehensive examination to be admitted to or continue in the PhD program, a student must:

1. Meet all the university’s residency and other requirements.

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

2. Successfully complete three advanced graduate courses (beyond those required for the MS), which have been approved by the student’s dissertation adviser.

3. Enroll in NANO 200, as required. See “Courses” for descriptions. 4. Pass the Literature Review Examination. This requirement must be successfully completed within one year

after passing the Comprehensive Examination. 5. Pass the PhD Qualifying Examination (Senate Exam) to be advanced to PhD candidacy. 6. Successfully complete and defend a dissertation, which in the opinion of the dissertation committee

contains original work that should lead to publication of at least one significant article in an appropriate refereed journal.

In principle, it should be possible to finish the MS degree in three quarters, and a PhD in an additional three years. PhD time limits are as follows: precandidacy—three years; support limit—six years; total time limit—seven years. (See “Graduate Division–PhD Time Limits” for further explanation.)

Departmental Examinations All PhD students are required to pass four examinations. The first is a written Comprehensive Examination, which should be taken within three to four quarters of full-time graduate study. The second is a Literature Review Examination (detailed below). The third is the PhD Senate Exam (often referred to as "Advancement to Candidacy Exam"). The last is the dissertation defense.

The Comprehensive Examination The examination will consist of questions from each of the five core courses. A passing grade is 60 percent for successful completion of the master’s degree, and 70 percent for qualification to the PhD program. The examination will not exceed six hours in duration. The examination is usually administered the week after spring quarter finals’ week in June. Typically, students take the exam after one year of full-time enrollment. This exam may only be retaken once before the end of the second year of study.

The Literature Review Examination The Literature Review Examination tests the student’s ability to prepare and present a comprehensive overview of a topic based on existing journal literature. It should be a comprehensive discussion of the literature, scientific theory, problems or theoretical deficiencies, and possible areas of research in some area related to nanoscience or nanoengineering. The topic may be in the general area in which the student plans to pursue his or her thesis research, or it may be in an unrelated field of nanoengineering. The topic must be approved by the three faculty member committee in advance of the seminar. The Literature Review Examination will conclude with a short preliminary overview of the students' research project or their research proposal. This exam must occur within one year of the student having passed the Comprehensive Examination.

The PhD Senate Exam: Upon completion of formal course requirements, each student will be required to take a written and oral qualifying examination that will advance the student to candidacy in the PhD program. It is often known as the “Senate Exam” or “Advancement to Candidacy” exam. Prior to this examination, each student, in consultation with his or her faculty adviser, will establish a dissertation committee of five faculty members. The committee will include the student’s PhD adviser as the chair of the committee. The committee will consist of three faculty members who are affiliated with the Department of NanoEngineering. At least two of the five committee members must be from a department other than the committee chair’s department and at least one of these two must be tenured. The thesis adviser will have the major responsibility for the student’s research and dissertation.

At UC San Diego, the university “Candidacy/Senate” Examination is a requirement for a graduate student to complete satisfactorily, once a thesis project has been decided upon. It is strongly recommended, except in special circumstances, that the student complete this examination prior to the end of the first three years in the program. The format for this examination is consistent with the highest standards held by UC San Diego. The student should write a detailed candidacy report in the format of an NIH, NSF, or similar grant proposal. The project and the report

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

should be interdisciplinary and should have input from the thesis adviser. Any publications or supplementary material may be attached. It is expected that the student will meet at least annually with the committee to update the members on his or her progress.

Dissertation Defense: This is the final PhD examination. Upon completion of the dissertation research project, the candidate writes a dissertation that must be successfully defended in an oral examination and public presentation conducted by the doctoral committee. A complete copy of the student’s dissertation must be submitted to each member of the doctoral committee two weeks before the defense. It is understood that this copy of the dissertation given to committee members will not be the final copy, and that the committee members may request changes in the text at the time of the defense. This examination may not be conducted earlier than three quarters after the date of advancement to doctoral candidacy. Acceptance of the dissertation by the Graduate Division and the university librarian represents the final step in completion of all requirements for the PhD.

Teaching Experience: Prior to the dissertation defense, the candidate must serve at least once as a teaching assistant, with the responsibility to hold a problem-solving section one hour a week.

Annual Evaluation: In the spring of each year, the faculty adviser evaluates each doctoral student’s overall performance in course work, research, and prospects for financial support for future years. A written assessment is given to the student after the evaluation. If a student’s work is found to be inadequate, the faculty may determine that the student cannot continue in the graduate program.

PhD in NanoEngineering with Specialization in Multiscale Biology

A PhD specialization in Multiscale Biology-spanning four divisions-Jacobs School of Engineering, Health Sciences, Biological Sciences, and Physical Sciences-is available to doctoral candidates in nanoengineering. The PhD specialization is designed to allow students to obtain standard basic training in their chosen field, along with training in integrative and quantitative analysis across multiple scales of biological organization from molecule to organism to health and disease. It educates a new cadre of PhD scientists to undertake interdisciplinary work at the interfaces between the biological, medical, physical, and engineering sciences.

Chemical Engineering Program (CENG)

Program Objectives

The Chemical Engineering Program has affiliated faculty from the Department of NanoEngineering, Department of Mechanical and Aerospace Engineering, Department of Chemistry and Biochemistry, and the Department of Bioengineering. The curricula at both the undergraduate and graduate levels are designed to support and foster chemical engineering as a profession that interfaces engineering and all aspects of basic sciences (physics, chemistry, and biology).

The primary educational objectives of the Chemical Engineering Program are

• To provide chemical engineering students with a strong technical education and communication skills that will enable them to have successful careers in a wide range of industrial and professional environments.

• To prepare chemical engineering students for rapidly changing technological environments with the core knowledge central to multidisciplinary development and personal improvement throughout their professional careers.

• To instill in chemical engineering students a strong sense of humanistic values and professionalism such that they can conduct ethically and knowledgeably regarding technological impact in societal issues.

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

The curriculum is designed to prepare chemical engineering graduates for further education and personal development through their entire professional career. We strive to accomplish these goals by providing a rigorous and demanding curriculum that incorporates lectures, discussions, laboratory and project development experiences in basic sciences, mathematics, engineering sciences, and design as well as the humanities and social sciences.

Chemical Engineering BS/MS Contiguous Program

A contiguous, terminal program leading to a bachelor of science and a master of science degree in chemical engineering is offered to a student with junior standing who has an overall UC San Diego GPA of 3.0 and a GPA of 3.5 in upper-division courses in the major. Students must apply for admission to the program during the last quarter of their junior year (more specifically, the fourth quarter prior to the receipt of the BS). Details of the program are available from the Department of NanoEngineering Graduate Affairs Office.

The MS program is intended to extend and broaden an undergraduate background and/or equip practicing engineers with fundamental knowledge in their particular fields. The degree is offered under both the Thesis Plan I and the Comprehensive Examination Plan II.

Program Accreditation

The BS program in chemical engineering is accredited by the Accreditation Board of Engineering and Technology (ABET/EAC).

Graduate Program

The Chemical Engineering Program offers graduate instruction leading to the MS and PhD in chemical engineering. The nanotechnology concentration signifies that four elective courses are chosen from the approved courses in this area.

Admission is in accordance with the general requirements of the graduate division, which requires at least a BS in some branch of engineering, sciences, or mathematics; an overall GPA of 3.0, and three letters of recommendation from individuals who can attest to the academic or professional competence and to the depth of their interest in pursuing graduate study. Students who have already received a prior MS in a similar field will not be admitted to the program.

In addition, all applicants are required to submit GRE General Test Scores. A minimum score of 550 on the Test of English as a Foreign Language (TOEFL) is required of all international applicants whose native language is not English. Students who score below 600 on the TOEFL are strongly encouraged to enroll in an English as a second language program before beginning graduate work. UC San Diego Extension offers an excellent English language program during the summers as well as the academic year.

Applicants are judged competitively. Based on the candidate’s background, qualifications, and goals, admission to the program is in one of three categories: MS-only, MS, or PhD. Admission to the MS-only category is reserved for students for whom the MS is likely to be the terminal graduate degree. The MS designation is reserved for students currently interested in obtaining an MS but who at a later time may wish to continue in the doctoral degree program. Admission to the PhD program is reserved for qualified students whose final aim is a doctoral degree.

Both NanoEngineering and chemical engineering nonmatriculated students are welcome to seek enrollment in graduate-level courses via UC Extension’s concurrent registration program, but an Extension student’s enrollment in a graduate course must be approved by the instructor.

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

Master’s Degree Program

The MS program is intended to extend and broaden an undergraduate education with fundamental knowledge in different fields. The degree may be terminal, or obtained on the way to the PhD. The degree is offered under both the Thesis Plan I and the Comprehensive Examination Plan II.

MS Time Limit Policy: Full-time MS students are permitted seven quarters in which to complete all requirements. While there is no written time limit for part-time students, the department has the right to intervene and set individual deadlines if it becomes necessary.

Course requirements: All MS students must complete a total of thirty-six units, which include a core of five courses (twenty units) chosen among fluid dynamics (CENG 210A, MAE 210B), heat and mass transfer (CENG 221AB), kinetics (CENG 252), and mathematics. To maintain a certain balance in the core, no more than two mathematics courses should be chosen among the choices of applied mathematics (MAE 294AB or Math 210AB) and numerical mathematics (MAE 290AB or Math 270AB).

No more than three courses (twelve units) of upper-division courses may be applied toward the total course work requirement. No more than a total of eight units of CENG 296 and 298 may be applied toward the course work requirement. Units in seminars (CENG 259) may not be applied toward the degree requirement.

Thesis Plan I: Completion of the research thesis (CENG 299) fulfills twelve units toward the total graduation requirement. The balance is made up of the five core courses (twenty units) and additional four elective courses (sixteen units) subject to the restrictions described above. The nanotechnology concentration signifies that four elective courses are chosen from the approved courses in this area.

Comprehensive Examination Plan II: This plan involves course work only and culminates in an oral comprehensive examination based on topics selected from the core courses. In addition to the five core courses (twenty units), one must choose an additional four electives (sixteen units) subject to the restrictions of CENG 259, 296, and 298 described above. Sample electives are listed in the table below. A student should consult his or her academic adviser to choose an appropriate course schedule, including alternatives in bioengineering, electrical and computer engineering, materials science, basic sciences, and mathematics. The nanotechnology concentration signifies that four elective courses are chosen from the approved courses in this area.

Fall Winter Spring Core selections CENG 210A CENG 221B CENG 252 CENG 221A MAE 210B MAE 290A or 294A MAE 290B or 294B Suggested electives MS 201A MS 201B MS 201C MAE 211 MAE 212 MAE 213 Math 270A Math 270B Math 270C Chem 211 Chem 212 Chem 213 Nanotechnology concentration CENG 211 CENG 213 CENG 212 CENG 214 CENG 215

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

Change of Degree: Upon completion of the requirements for the MS degree, students admitted as MS-only or MS candidates are not automatically eligible for admission to the PhD program.

MS only and MS candidates who subsequently wish to pursue a doctorate must submit an application for a change in status to their examining committee. The application, if approved by the committee, must be signed by a faculty member who expects to serve as the student’s PhD adviser. The student must also submit a general petition for graduate students to effect the change of status. If the student elects the comprehensive examination plan for the MS, the examining committee may recommend that the comprehensive examination may replace the preliminary qualifying examination expected of PhD students.

Doctoral Degree Program

The PhD program is intended to prepare students for a variety of careers in research and teaching. The emphasis is on research. In general, there are no formal course requirements. All students, in consultation with their advisers, develop appropriate course programs that will prepare them for the Preliminary Qualifying Examination and for their dissertation research. These programs must be planned to meet the time limits established to advance to candidacy and to complete the requirements of the degree.

All PhD students are required to pass three examinations. The first is a Preliminary Qualifying Examination, which should be taken within three to four quarters of full-time graduate study. The second is the PhD Qualifying Examination. The last is the Dissertation Defense.

Preliminary Qualifying Examination: The examination is intended to determine a candidate’s basic understanding of engineering fundamentals and the candidate’s ability to pursue successfully a research project at a level appropriate for the doctorate. The scope of the examination is based on topics selected from the core curriculum as listed under the MS program. A candidate is expected to demonstrate knowledge equivalent to these courses and formal enrollment record is not a prerequisite. The format is an oral examination administered by a committee of three faculty members in the Chemical Engineering Program. The candidate should present to the committee, prior to the examination, the five core courses that will constitute the basis of the examination.

Depth Requirement: A candidate must have the ability to perform in-depth analysis in the dissertation topic. A candidate should consult with the thesis adviser to develop a proper course program if it is deemed necessary. Depending on an individual’s background and the nature of the research problem, a candidate should either complete a set of a minimum of four courses or demonstrate to the thesis adviser the equivalent knowledge and ability.

PhD Qualifying Examination: Prior to taking this examination, the candidate must have completed the departmental qualifying examination, obtained a faculty research adviser, and must have made initial progress on a chosen dissertation project. At the time of application for advancement to candidacy, a doctoral committee responsible for the remainder of the student’s graduate program is appointed by the Graduate Council under the policy listed in the “Graduate Admission ” section of the UC San Diego General Catalog. The committee conducts the PhD Qualifying Examination, during which the student must demonstrate the ability to engage in thesis research. The process involves the presentation of a plan for the thesis research project. The committee may ask questions directly or indirectly related to the project and general questions that it determines to be relevant. Upon successful completion of the examination, subject to the UC San Diego time limit policy, the student is advanced to candidacy and is awarded the candidate in philosophy degree (see “Graduate Admission ” section in this catalog).

Teaching Experience: Prior to the dissertation defense, the candidate must serve at least once as a teaching assistant with the responsibility to hold a problem-solving section one hour a week.

COPY FROM 2016–17 UC SAN DIEGO GENERAL CATALOG

October 26, 2016 Update NanoEngineering Graduate Curriculum (Revised Oct. 2016)

Dissertation Defense: This is the final PhD examination. Upon completion of the dissertation research project, the candidate writes a dissertation that must be successfully defended in an oral examination and public presentation conducted by the doctoral committee. A complete copy of the student’s dissertation must be submitted to each member of the doctoral committee four weeks before the defense. It is understood that this copy of the dissertation given to committee members will not be the final copy, and that the committee members may request changes in the text at the time of the defense. This examination may not be conducted earlier than three quarters after the date of advancement to doctoral candidacy. Acceptance of the dissertation by the Graduate Division and the University Librarian represents the final step in completion of all requirements for the PhD.

PhD Time Limit Policy: Precandidacy status is limited to four years. Doctoral students are eligible for university support for six years. The defense and submission of the doctoral dissertation must be within seven years.

Annual Evaluation: In the spring of each year, the faculty adviser evaluates each doctoral student’s overall performance in course work, research, and prospects for financial support for future years. A written assessment is given to the student after the evaluation. If a student’s work is found to be inadequate, the faculty may determine that the student cannot continue in the graduate department.

PhD in Chemical Engineering with Specialization in Multiscale Biology

A PhD specialization in Multiscale Biology-spanning four divisions-Jacobs School of Engineering, Health Sciences, Biological Sciences, and Physical Sciences-is available to doctoral candidates in chemical engineering. The PhD specialization is designed to allow students to obtain standard basic training in their chosen field, along with training in integrative and quantitative analysis across multiple scales of biological organization from molecule to organism to health and disease. It educates a new cadre of PhD scientists to undertake interdisciplinary work at the interfaces between the biological, medical, physical, and engineering sciences.