Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First...
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![Page 1: Progress Against Ovarian Cancer. 1970–1979 Progress Against Ovarian Cancer 1970–1979 1978: First effective combination chemotherapy regimen for ovarian.](https://reader035.fdocuments.us/reader035/viewer/2022062511/55148896550346ea6e8b4d4e/html5/thumbnails/1.jpg)
Progress Against Ovarian
Cancer
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Progress Against Ovarian Cancer
1970–1979
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Progress Against Ovarian Cancer
1970–19791978: First effective combination chemotherapy regimen for ovarian cancer
1978: Cisplatin approved for advanced ovarian cancer
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Progress Against Ovarian Cancer
1980–1989
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Progress Against Ovarian Cancer
1980–19891981: Oral contraceptives found to cut ovarian cancer risk
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Progress Against Ovarian Cancer
1980–1989Mid-1980s: Scientists discover ''biomarker'' tied to ovarian cancer – CA-125
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Progress Against Ovarian Cancer
1980–19891989: FDA approves carboplatin for ovarian cancer
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Progress Against Ovarian Cancer
1990–1999
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Progress Against Ovarian Cancer
1990–19991992–1994: Taxanes emerge as vital chemotherapy option for ovarian, breast cancer
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Progress Against Ovarian Cancer
1990–19991996: New chemotherapy drug for advanced ovarian cancer
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Progress Against Ovarian Cancer
1990–1999Late 1990s: BRCA1 and BRCA2 gene mutations linked to increased ovarian cancer risk
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Progress Against Ovarian Cancer
1990–19991999: FDA approves liposomal doxorubicin for advanced ovarian cancer
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Progress Against Ovarian Cancer
2000–Present
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Progress Against Ovarian Cancer
2000–Present2003: New chemotherapy regimen – docetaxel and paclitaxel – provides important treatment option
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Progress Against Ovarian Cancer
2000–Present2005: Researchers work to decode the ovarian cancer genome
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Progress Against Ovarian Cancer
2000–Present2006: Researchers find some ovarian cancers begin in the fallopian tubes
2006: Direct chemotherapy approach increases survival
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Progress Against Ovarian Cancer
2000–PresentLate 2000s: Researchers identify at least two ovarian cancer subtypes
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Progress Against Ovarian Cancer
2000–Present2009: Preventive surgery confirmed to reduce breast and ovarian cancer risk in women with BRCA gene mutations
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Progress Against Ovarian Cancer
2000–Present2010: Regular CA125 testing to monitor for ovarian cancer recurrence is questioned
2010: Bevacizumab significantly delays progression of advanced ovarian cancer
2010: Pre-surgery chemotherapy proven an effective option for women with advanced ovarian cancer
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Progress Against Ovarian Cancer
Five-Year Survival
34
36
38
40
42
44
46
1975
1977
1979
1981
1983
1985
1987
1989
1991
1993
1995
1997
1999
2001
2003
2005
2007
2009
Year of Diagnosis
% o
f Pa
tien
ts S
urv
ivin
g F
ive
Ye
ars
Source: National Cancer Institute
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Progress Against Ovarian Cancer
Mortality
5
6
7
8
9
10
11
12
13
1970
1972
1974
1976
1978
1980
1982
1984
1986
1988
1990
1992
1994
1996
1998
2000
2002
2004
2006
2008
2010
Year of Death
Ca
nce
r D
ea
ths
pe
r 1
00
,00
0 P
eo
ple
Source: National Cancer Institute
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Progress Against Ovarian Cancer
New Cases
11
12
13
14
15
16
17
18
19
1973
1975
1977
1979
1981
1983
1985
1987
1989
1991
1993
1995
1997
1999
2001
2003
2005
2007
2009
Year of Diagnosis
Ne
w C
an
cer
Ca
ses
pe
r 1
00
,00
0 P
eo
ple
Source: National Cancer Institute
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