Program - ipk-gatersleben.de · in centromere assembly and geno-me stability ... Gregor Mendel...

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Sunday, June 03, 2018 18:00 Andreas Graner Managing Director, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany Welcome 18:15 Fred Berger Gregor Mendel Institute, Vienna, Austria Plenary talk: Histone variants and chromatin landscapes 19:15 Reception Monday, June 04, 2018 Session 1: Genetic and epigene- tic influences on chromosome stability (I) Chair: Dorothy Shippen, Avraham Levy 08:30 Dorothy Shippen Texas A&M University, USA Breaking new ground: the emer- gence of non-canonical functions for telomerase-associated subunits in Arabidopsis 09:00 Avraham Levy Weizmann Institute, Rehovot, Israel Targeted recombination between homologous chromosomes in so- matic plant cells 09:30 Alevtina Ruban IPK Gatersleben, Germany Tissue type-specific distribution of supernumerary B chromosomes, is it a result of programmed elimi- nation or reflection of genome in- stability? 09:45 Veronika Burešová Institute of Experimental Botany, Olomouc, Czech Republic Spatial organization of rye chroma- tin in wheat host genome revealed by 3D-FISH 10:00 Inna Lermontova IPK, Gatersleben, Germany Functional role of A. thaliana KNL2 in centromere assembly and geno- me stability 10:15 Sachihiro Matsunaga Tokyo University of Science, Japan Centromere distribution by the two-step regulation through a sub- nuclear complex 10:30 Coffee Break Session 1: Genetic and epigene- tic influences on chromosome stability (II) Chair: Julie Law, Charles White 11:00 Julie Law Salk Institute San Diego, USA Locus-specific control of the de novo DNA methylation pathway in Arabidopsis 11:30 Dolores Córdoba-Cañero University of Cordoba, Spain DNA damage-binding protein 2 (DDB2) regulates active DNA de- methylation mediated by ROS1 5-methylcytosine DNA glycosylase 11:45 Callie R. Kobayashi Texas A&M University, College Station, USA NOP2 and EMC8/9: New genes involved in telomere length set point in Arabidopsis thaliana 12:00 Tony Heitkam TU Dresden, Germany SINEs contribute to gene evoluti- on, regulation and genome rear- rangement in Solanaceae plants 12:15 Markus Kuhlmann IPK Gatersleben, Germany EFFECTOR OF TRANSCRIPTION (ET) factors are novel plant-speci- fic regulators of genomic DNA me- thylation in Arabidopsis 12:30 Yevgeniy Shakirov Institute of Fundamental Medicine and Biol- ogy, Kazan, Russian Federation Genomic assays in Arabidopsis thaliana identify several loci invol- ved in telomere length control 12:45 Dmitri Demidov IPK, Gatersleben, Germany Characterization of A. thaliana mu- tants for CENH3 interacting prote- ins and plants with deregulated ex- pression of centromeric repeats as potential haploid inducers 13:00 Lunch Session 2: Replication, cell cyc- le, DNA repair & somatic recom- bination (I) Chair: Anne Britt, Teresa Roldan-Arjona 14:00 Anne Britt University of California, Davis, USA A wide variety of modifications of CENH3 result in haploid induction 14:30 Teresa Roldan-Arjona University of Cordoba, Spain Base excision: at the intersection between DNA repair and epigene- tics 15:00 Ales Pecinka Institute of Experimental Botany, Olomouc, Czech Republic SMC5/6 complex is essential for repair of zebularine-induced en- zymatic DNA-protein crosslinks in Arabidopsis 15:15 Petra Schrumpfova Prochazkova Masaryk University, Brno, Czech Republic The plant pontin and reptin homo- logues co-localize with TERT and telomere repeat binding proteins in vivo 15:30 Ingo Schubert IPK, Gatersleben, Germany Linking genome size and karyoty- pe evolution via DSB repair 15:45 Naoki Takahashi Nara Institute of Science and Technology, Japan DNA damage activates two distinct signaling pathways controlling DNA repair and cell cycle arrest 16:00 Fruits and Cake 16:30 Poster presentation and subse- quent poster viewing (Session 1,2) 18:30 Joachim Schiemann Julius Kuehn Institute, Quedlinburg, Germany Public talk: Bio und grüne Gen- technik – geht das? 19:30 BBQ & Beer Tuesday, June 5, 2018 Session 2: Replication, cell cyc- le, DNA repair & somatic recom- bination (II) Chair: Lieven de Veylder, Holger Puchta 08:30 Lieven de Veylder VIB and University Ghent, Belgium The importance of DNA stress checkpoint control in agriculture 09:00 Holger Puchta; Felix Wolter Karlsruhe Institute of Technology, Germany Enhancing in planta gene targe- ting in Arabidopsis Holger Puchta; Annika Dorn Karlsruhe Institute of Technology, Germany The RecQ-like helicase HRQ1 is in- volved in DNA crosslink repair in Arabidopsis in a common pathway with the Fanconi anemia-associa- ted nuclease FAN1 and the post- replicative repair ATPase RAD5A 09:30 Eva Sykorova Institute of Biophysics, Brno, Czech Repub- lic Telomerase interactions - from plants to human or there and back again 09:45 Petr Fajkus Institute of Biophysics, Brno, Czech Repub- lic New insight into TERT evolution during plant speciation 10:00 Thomas Wicker University of Zurich, Switzerland Sloppy repair of DNA damage caused by transposable elements – a major driving force of genome evolution LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH (IPK) Corrensstraße 3 D-06466 Seeland OT Gatersleben Contact: Regina Devrient Managing Office | Public Relations Phone: (+49) 039482 5 837 Email: [email protected] http://www.ipk-gatersleben.de/meetings/plant-genome-stability-and-change/ 10:15 Poyu Chen University of Hamburg, Germany Isolation of novel DNA damage re- gulators based a genome-wide identification of the binding sites of the Arabidopsis Retinoblastoma homolog RBR1 10:30 Coffee Break Session 3: Meiotic processes & recombination (I) Chair: Monica Pradillo Orellana, Peter Schlögelhofer 11:00 Monica Pradillo Orellana Universidad Complutense, Madrid, Spain When the nucleus meets the cyto- plasm: A role for nuclear envelope- associated proteins in meiosis and DNA repair 11:30 Peter Schlögelhofer University of Vienna, Austria Control of meiotic recombination at the rDNA 12:00 Olga Raskina University of Haifa, Israel Genome architecture, repatterning, and diversification in Aegilops speltoides Tausch (Poaceae, Triti- ceae) 12:15 Steven Dreissig IPK, Gatersleben, Germany Measuring meiotic recombination by sequencing of single pollen nu- clei 12:30 Guoliang Yuan Gent University, Belgium PROTEIN PHOSHATASE 2A pro- tects sister chromatid cohesion by maintaining REC8 at the centro- meres in Arabidopsis. 12:45 David Kopecky Institute of Experimental Botany, Olomouc, Czech Republic How to achieve genome stability in interspecific grass hybrids? 13:00 Lunch Break Session 3: Meiotic processes & recombination (II) Chair: Ian Henderson, Stefan Heckmann 14:00 Ian Henderson University of Cambridge, UK The Arabidopsis meiotic DSB and chromatin landscapes 14:30 Stefan Heckmann IPK, Gatersleben, Germany Can we harness meiosis in barley? 14:45 Marie-Therese Kurzbauer Max F. Perutz Laboratories, University of Vi- enna, Austria; AtATM limits meiotic DNA double- strand break formation and recom- bination 15:00 Cécile Raynaud Institute of Plant Sciences Paris Saclay, France DNA polymerase epsilon plays a crucial role in the maintenance of the plant genome integrity. 15:15 Nico de Storme Ghent University, Belgium Heat-induced defects in male mei- otic cell division and chromosome segregation Program

Transcript of Program - ipk-gatersleben.de · in centromere assembly and geno-me stability ... Gregor Mendel...

Sunday, June 03, 2018

18:00 Andreas Graner Managing Director, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany

Welcome

18:15 Fred Berger Gregor Mendel Institute, Vienna, Austria

Plenary talk: Histone variants and chromatin landscapes

19:15 Reception

Monday, June 04, 2018

Session 1: Genetic and epigene-tic influences on chromosome stability (I) Chair: Dorothy Shippen, Avraham Levy

08:30 Dorothy Shippen Texas A&M University, USA

Breaking new ground: the emer-gence of non-canonical functions for telomerase-associated subunits in Arabidopsis

09:00 Avraham Levy Weizmann Institute, Rehovot, Israel

Targeted recombination between homologous chromosomes in so-matic plant cells

09:30 Alevtina Ruban IPK Gatersleben, Germany

Tissue type-specific distribution of supernumerary B chromosomes, is it a result of programmed elimi-nation or reflection of genome in-stability?

09:45 Veronika Burešová Institute of Experimental Botany, Olomouc, Czech Republic

Spatial organization of rye chroma-tin in wheat host genome revealed by 3D-FISH

10:00 Inna Lermontova IPK, Gatersleben, Germany

Functional role of A. thaliana KNL2 in centromere assembly and geno-me stability

10:15 Sachihiro Matsunaga Tokyo University of Science, Japan

Centromere distribution by the two-step regulation through a sub-nuclear complex

10:30 Coffee Break

Session 1: Genetic and epigene-tic influences on chromosome stability (II) Chair: Julie Law, Charles White

11:00 Julie Law Salk Institute San Diego, USA

Locus-specific control of the de novo DNA methylation pathway in Arabidopsis

11:30 Dolores Córdoba-Cañero University of Cordoba, Spain

DNA damage-binding protein 2 (DDB2) regulates active DNA de-methylation mediated by ROS1 5-methylcytosine DNA glycosylase

11:45 Callie R. Kobayashi Texas A&M University, College Station, USA

NOP2 and EMC8/9: New genes involved in telomere length set point in Arabidopsis thaliana

12:00 Tony Heitkam TU Dresden, Germany

SINEs contribute to gene evoluti-on, regulation and genome rear-rangement in Solanaceae plants

12:15 Markus Kuhlmann IPK Gatersleben, Germany

EFFECTOR OF TRANSCRIPTION (ET) factors are novel plant-speci-fic regulators of genomic DNA me-thylation in Arabidopsis

12:30 Yevgeniy Shakirov Institute of Fundamental Medicine and Biol-ogy, Kazan, Russian Federation

Genomic assays in Arabidopsis thaliana identify several loci invol-ved in telomere length control

12:45 Dmitri Demidov IPK, Gatersleben, Germany

Characterization of A. thaliana mu-tants for CENH3 interacting prote-ins and plants with deregulated ex-pression of centromeric repeats as potential haploid inducers

13:00 Lunch

Session 2: Replication, cell cyc-le, DNA repair & somatic recom-bination (I) Chair: Anne Britt, Teresa Roldan-Arjona

14:00 Anne Britt University of California, Davis, USA

A wide variety of modifications of CENH3 result in haploid induction

14:30 Teresa Roldan-Arjona University of Cordoba, Spain

Base excision: at the intersection between DNA repair and epigene-tics

15:00 Ales Pecinka Institute of Experimental Botany, Olomouc, Czech Republic

SMC5/6 complex is essential for repair of zebularine-induced en-zymatic DNA-protein crosslinks in Arabidopsis

15:15 Petra Schrumpfova Prochazkova Masaryk University, Brno, Czech Republic

The plant pontin and reptin homo-logues co-localize with TERT and telomere repeat binding proteins in vivo

15:30 Ingo Schubert IPK, Gatersleben, Germany

Linking genome size and karyoty-pe evolution via DSB repair

15:45 Naoki Takahashi Nara Institute of Science and Technology, Japan

DNA damage activates two distinct signaling pathways controlling DNA repair and cell cycle arrest

16:00 Fruits and Cake

16:30 Poster presentation and subse-quent poster viewing (Session 1,2)

18:30 Joachim Schiemann Julius Kuehn Institute, Quedlinburg, Germany

Public talk: Bio und grüne Gen-technik – geht das?

19:30 BBQ & Beer

Tuesday, June 5, 2018

Session 2: Replication, cell cyc-le, DNA repair & somatic recom-bination (II) Chair: Lieven de Veylder, Holger Puchta

08:30 Lieven de Veylder VIB and University Ghent, Belgium

The importance of DNA stress checkpoint control in agriculture

09:00 Holger Puchta; Felix Wolter Karlsruhe Institute of Technology, Germany

Enhancing in planta gene targe-ting in Arabidopsis

Holger Puchta; Annika Dorn Karlsruhe Institute of Technology, Germany

The RecQ-like helicase HRQ1 is in-volved in DNA crosslink repair in Arabidopsis in a common pathway with the Fanconi anemia-associa-ted nuclease FAN1 and the post-replicative repair ATPase RAD5A

09:30 Eva Sykorova Institute of Biophysics, Brno, Czech Repub-lic

Telomerase interactions - from plants to human or there and back again

09:45 Petr Fajkus Institute of Biophysics, Brno, Czech Repub-lic

New insight into TERT evolution during plant speciation

10:00 Thomas Wicker University of Zurich, Switzerland

Sloppy repair of DNA damage caused by transposable elements – a major driving force of genome evolution

LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH (IPK)Corrensstraße 3D-06466 Seeland OT Gatersleben

Contact:Regina DevrientManaging Office | Public RelationsPhone: (+49) 039482 5 837Email: [email protected]

http://www.ipk-gatersleben.de/meetings/plant-genome-stability-and-change/

10:15 Poyu Chen University of Hamburg, Germany

Isolation of novel DNA damage re-gulators based a genome-wide identification of the binding sites of the Arabidopsis Retinoblastoma homolog RBR1

10:30 Coffee Break

Session 3: Meiotic processes & recombination (I) Chair: Monica Pradillo Orellana, Peter Schlögelhofer

11:00 Monica Pradillo Orellana Universidad Complutense, Madrid, Spain

When the nucleus meets the cyto-plasm: A role for nuclear envelope-associated proteins in meiosis and DNA repair

11:30 Peter Schlögelhofer University of Vienna, Austria

Control of meiotic recombination at the rDNA

12:00 Olga Raskina University of Haifa, Israel

Genome architecture, repatterning, and diversification in Aegilops speltoides Tausch (Poaceae, Triti-ceae)

12:15 Steven Dreissig IPK, Gatersleben, Germany

Measuring meiotic recombination by sequencing of single pollen nu-clei

12:30 Guoliang Yuan Gent University, Belgium

PROTEIN PHOSHATASE 2A pro-tects sister chromatid cohesion by maintaining REC8 at the centro-meres in Arabidopsis.

12:45 David Kopecky Institute of Experimental Botany, Olomouc, Czech Republic

How to achieve genome stability in interspecific grass hybrids?

13:00 Lunch Break

Session 3: Meiotic processes & recombination (II) Chair: Ian Henderson, Stefan Heckmann

14:00 Ian Henderson University of Cambridge, UK

The Arabidopsis meiotic DSB and chromatin landscapes

14:30 Stefan Heckmann IPK, Gatersleben, Germany

Can we harness meiosis in barley?

14:45 Marie-Therese Kurzbauer Max F. Perutz Laboratories, University of Vi-enna, Austria;

AtATM limits meiotic DNA double-strand break formation and recom-bination

15:00 Cécile Raynaud Institute of Plant Sciences Paris Saclay, France

DNA polymerase epsilon plays a crucial role in the maintenance of the plant genome integrity.

15:15 Nico de Storme Ghent University, Belgium

Heat-induced defects in male mei-otic cell division and chromosome segregation

Program

15:30 Shuhei Nasuda Kyoto University, Japan

Analysis on the zygotic chromoso-me breakage induced by the ga-metocidal gene Gc2-4Ssh in wheat

15:45 Martina Dvorackova CEITEC Masaryk University, Brno, Czech Republic

Tracking the dynamics of nucleo-lar processes

16:00 Alexander Blackwell University of Cambridge, Cambridge, Uni-ted Kingdom

The role of Arabidopsis mismatch repair proteins in meiotic recombi-nation

16:15 Fruits and Cake

16:45 Poster presentation and subse-quent poster viewing (Session 3, 4)

19:00 Guided evening tour in Quedlin-burg

20:00 Conference dinner Hotel Schlossmühle Kaiser Otto Straße 28 Quedlinburg

Wednesday, June 6, 2018

Session 4: Genome enginee-ring, approaches & applications (I) Chair: Jens Boch, Götz Hensel

08:30 Jens Boch Leibniz University Hannover, Germany

Editing plant genomes for patho-gen resistance

09:00 Ayako Okuzaki Tamagawa University, Japan

Genome editing of the fatty acid desaturase 2 gene in Brassica na-pus

09:15 Niharika Sashidhar Kiel University, Germany

Genome editing strategies for mul-tiple knock out of phytic acid pa-thway genes in Brassica napus

09:30 Maartje van Kregten Leiden University, Netherlands

Genetic modification of plants re-sults from polymerase theta-media-ted end-joining

09:45 Huirong Gao DuPont Pioneer, USA

Applications of CRISPR-Cas enab-led advanced breeding technology in trait development in maize

10:00 Masaki Endo Institute of Agrobiological Sciences, NARO, Tsukuba, Japan

Genome editing in plants with en-gineered SpCas9 using NG-PAM

10:15 Michał Tomasz Kwiatek Institute of Plant Genetics of the Polish Aca-demy of Sciences, Poznan, Poland

Transfer of chromatin of wild goat-grasses (Aegilops sp.) carrying genes responsible for resistance to leaf rust into triticale (× Triticose-cale Wittmack) using chromosome engineering

10:30 Coffee Break

Session 4: Genome enginee-ring, approaches & applications (II) Chair: Sylvia de Pater, Seiichi Toki

11:00 Sylvia de Pater University of Leiden, The Netherlands

CRISPR/Cas induced mutagene-sis in Arabidopsis DNA repair mu-tants

11:30 Seiichi Toki National Agriculture and Food Research Organization, Tsukuba, Japan

New tools for plant genome engi-neering

12:00 Nathalie Durut Gregor Mendel Institute of Molecular Plant Biology, Vienna, Austria

Targeted double strand breaks in plants to study the role of chroma-tin and ncRNA during DNA repair

12:15 Goetz Hensel IPK, Gatersleben, Germany

Generation of new barley mutant alleles of LIPOXYGENASE 1 using CRISPR RNA/Cas9-endonuclease technology

12:30 Tal Dahan-Meir Weizmann Institute, Rehovot, Israel

Efficient in planta gene targeting using geminiviral replicons and the CRISPR/cas9 system

12:45 Haruyasu Hamada NARO Hokkaido Agriculture Research Cen-ter, Japan

An in planta genome editing me-thod for genetic engineering of commercial wheat

Summary and closing remarks

13:00 Barbara Hohn Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

Summarizing the meeting

13:30 Lunch and departure

Program

Support

We are looking forward to welcome you in Gatersleben.