Prof.Rodica-Mariana Ion

Prof.Rodica-Mariana IonICECHIM, Analytical Department, Bucharest, Romania;

Valahia University, Targoviste, Romania

Tel/fax: +4 021 316 30 94

E-mail: [email protected]

[email protected]

Romanian potential in area of biobased products

Biotechnology ?

• Biotechnology = application of integrated biological

sciences and engineering technology for the use of

living organisms, biologically active acellular

structures and their molecular analogues in order to

produce goods and services (Bahrim, 2004).

• produce a large variety of products (medicines,

pharmaceuticals, enzymes, nutraceuticals, food and

micro-organisms)Bridge Conference, Bucharest, 12 June 2013

Biotechnology in Romania

Bridge Conference, Bucharest, 12 June 2013

National Center for Programmes Management

Structure and finnancial support for 2007 - 2013

5400 mil lei

~1500 mil Euros

540

540

756

756

648

378

810

432

540

0

100

200

300

400

500

600

700

800

900

DC 1 DC 2 DC 3 DC 4 DC 5 DC 6 DC 7 DC 8 DC 9


Romanian Biotechnology

Integrated Research and Training Centre for Applied biotechnology

in Food Industry – BIOALIMENT

(http://www.bioaliment.ugal.ro/index_en.html)

Biotechnology Platform based on knowledge

(http://www.usamvcluj.ro/html/cercetare/platforma

BIOINGTECH Platform

(http://www.pub.ro/ro/cercetare/platforme/platforme-02.html)

PFCI – RENATSIL - Platform for sustainable recovery of natural

resources through biotechnology and ecological processes in tourism,

forestry and wood processing (http://www.unitbv.ro/renatsil/index.html).


Romanian biotechnology BRIDGE

http://www.flickr.com/photos/


GLOBAL EFFORT

CONCERNING

ENVIRONMENTAL

PROTECTION AND SAFETY

SUSTAINABLE DEVELOPMENT

OF ECOSYSTEMS AND GREEN

UTILIZATION OF BIO-

RESOURCES

CHALLENGE OF THE IIIrd

MILLENNIUM

BIO-PRODUCTS FOR NANOMEDICINE

National Institute of R&D for Chemistry and Petrochemistry – ICECHIM, Bucharest,

Romania


Medical and Pharmaceutical Biotechnology

• New products for preventive medicine

• Systems biology for drug discovery

• Regenerative medicine

• Biomarkers and tailored drugs

• Biomaterials

• Drug design and targeting


Biotechnology for Bioenergy

• Biotechnology to the next generation biofuels production

• Microalgal Biotechnology


Food Biotechnology

• Nanomaterials in food and food packaging

• Nanotechnologies and nanosensors in food processing, food safety, biosecurity and product traceability

• Functional food and nutragenomics


Environmental Biotechnology

• Biotransformation of organics and heavy metals

• Contaminated soils, groundwater and sediments

• Bioconversion of organic wastes and by-products into valued added products

• Biotechnology applied to conservation and restauration of cultural heritage materials


Chemistry for developing biotechnology

• Analytical biotechnology

• Nanobiotechnology

• Biomaterials

• Toxicity evaluation and safety control by biotechnological approach


Biotechnologies in therapeutics

COST Project: D20, D39, TD

1002, CM 1002,

Photodynamic therapy


actinic keratosis

Applications of photodynamic therapy in dermatology


actinic keratosis, superficial basal cell carcinoma (5 mm), Bowen’s disease


Porphyrin Photosensitiser for dermatologic therapy

AWARDS RECEIVED AT INVENTION SALONS


NANO-ANTIOXIDANTS FROM FOOD AS DRUGS AGAINST

CANCER

Vein ulcer treatment

FP6- DEVELONUTRI


LIKE-HORMONE NATURALEXTRACTS

HARMONY DUO COMMERCIAL PRODUCT

• DAIDZEIN

• GENISTEIN

• BIOCHANIN A

• FORMONONETIN

• GLICITEIN

• SECOISOLARICIRESIN

OL

• MATAIRESINOL

• MELATONIN

• VITAMINS


Vitiligo is a non-contagious pigment disorder. It is

characterized by hypo pigmented patches of skin

due to progressive destruction of melanin pigment

producing melanocytes.

NATURAL EXTRACTS FOR VITILIGO


Before therapy During therapy After therapy

OH

H

O

O

OCH3

OCH3

CH3

H

9 8

7

6

54

3

2

1

13

1211

10

VITILIGO TREATMENT BY PDT WITH NATURAL EXTRACTS


ALGAE VALORIZATION


Commercial products from algae

can produce

lipids (oil) (20-65% by weight);

carbohydrates/sugars (10-40%);

proteins ( 20-40%)

Micro-algae the most fast-growing plant on Earth - grows in 100 times faster, than trees. Usually the weight of micro-algae for a day is doubled


PHOTOBIOREACTOR FOR SUSTAINED SEQUESTRATION OF CARBON DIOXIDE FROM

GREENHOUSE GASES

Patent Application A/00288 / 06.04.2009


ECOLOGICI CAL SOLVENTS

SUNFLOWER OIL METHANO

LISA

PURIFICA

TION

ECOLOGICAL

SOLVENT

Bridge Conference, Bucharest, 12

June 2013

BIOMASS VALORISATION

UE Projects: COST Project 0903


AWARDS RECEIVED AT INVENTION SALONS

ORIGINAL

TECHNOLOGY FOR

BIODIESEL AND

ECOLOGICAL

SOLVENT

MANUFACTURE


Sibiu area restoration and conservation of cultural heritage


Biotechnology = quality of life in a sustainable

society


Knowledge

triangle

Research Education

Innovation - Creating an

European Research

Area in the field of

Industrial

Biotechnology

Main objectives

Implementing

joint calls for

transnational

projects

Networking of

research activities

conducted at

national or regional

levelBridge Conference, Bucharest, 12 June 2013

Innovation Checks

-Success story-• Fortifying drink;

• Trichoderma-based fungicidal;

• Odors for ornamental crops;

• organic solvents;

• Organic compositions for mites in bee families;

• Bioproducts for removing carcinogens and potentialcarcinogens in soils polluted with oil products;

• Supplements based oils and derivatives of fatty acids formilk production biostimulation goats;

• Herbal tinctures extracted twice;

• Foliar fertilizer compositions;

• Transparent microemulsion sunscreen;

• Insecticides based on natural pyrethrinsBridge Conference, Bucharest, 12 June 2013

Acknowledgement

• PNII 222/2012

• CEEX 18/2005

• PNII/4.2 22-085/2008

• PN2/4.5 52-134/2008

• PN2/4.9 91-011/18.09.2007

• PN2/4.5 51-080/18.09.2007

• FP6 - DEVELONUTRI

• PN2/2-CP xxx-CP/2008

• LIFE 10 ENV/RO/000734


Prof.Rodica-Mariana Ion

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