Process Instrumentation and Analytics - Industrial...

Answers for industry.

Pharmaceutical Industry

Process Instrumentation and AnalyticsHighest product quality thanks to perfect integration of all components

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Table of Contents

Your challenge is our passion 03

Your partner for precision 04

Chemical Active PharmaceuticalIngredients

06

Biological Active PharmaceuticalIngredients

08

Pharmaceutical manufacturing (solids) 10

Pharmaceutical manufacturing (liquids) 12

Infrastructure 14

Selected technologies

Pressure, temperature, valve positioning, weighing, software

16

Process Instrumentationand Analytics product range

21

Totally Integrated Automation 24

Industrial Identification 26

Services and support 27

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The competitive environment for pharmaceutical manu-facturing is more intensive than ever. Wider scientific and demographic trends are also shaping the future direction of production. We are not far from a time when pharma-ceutical manufacturing will need to prepare for an era of personalized medicines. At the same time, the patient population is living longer with a consequent impact on demand and the creation of additional pricing pressures. Pharmaceutical production is preparing for a future that will see new flexible manufacturing strategies being de-ployed alongside high-volume output.

Gaining control of processes and integrating them with overall manufacturing control systems and demand-driven logistics chains will be the key to future success. Siemens delivers world-class capabilities to meet the challenges faced by pharmaceutical manufacturers. Siemens is able to address a number of vital process instrumentation and analytics requirements. Its global reach and product port-folio enables Siemens to meet your development needs and requirements.

When you partner with Siemens, you get:• A product portfolio for key process steps in the

value chain• Solutions to improve productivity, quality and

supply challenges• Fewer different components – simplifying spare parts

inventory and ensuring highly efficient maintenance• The assurance of a leading global brand delivering

leading-edge automation technology• People who understand your industry needs and can

configure solutions to match your operating conditions

Your challenge is our passionPharmaceutical manufacturers are seeking to press ahead quickly in response to competitive and pricing pres-

sures in the pharmaceutical market. Improvements in performance and capability are high on the agenda with

the goals of reducing time-to-market, lowering the cost-base, increasing quality and efficiency and matching

market requirements with a demand-driven supply chain. At the same time, regulatory changes provide signifi-

cant opportunities for improvement and innovation in the production and manufacture of pharmaceuticals.

Your partner for precisionPrecision and accuracy are vital in pharmaceutical manufacturing. Patient safety and regulatory compliance

are critical. Companies need to enjoy complete trust and confidence, knowing that their process instrumentation

allows them full control over their operations.

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Whatever part of the industry you focus on, whether you are a manufacturer of biological or chemical active phar-maceutical ingredients (APIs) or are engaged in dosage vector manufacturing, you can be assured that Siemens quality and product know-how will help you meet your business and customer goals:

Product life cycle planningYou need a partner who can meet your needs throughout the entire life cycle of your product, whether by hastening the drug from trials into full-scale market production or by helping you to achieve manufacturing excellence and while maintaining a competitive cost-base.

Optimal asset valuationThe diagnostic capabilities of our instrumentation solu-tions, in combination with evaluation and MES systems, provide you with the information you need to leverage maximum productivity from your manufacturing assets. You are able to plan effectively for any production changes and maintenance.

Pharma knowledgeOur products and knowledge of the industry can help you stay at the forefront of the pharmaceutical industry with respect to regulatory compliance and your competitive edge. We appreciate, for example, that process analytical technology (PAT) is much more than just sensing and includes both design and production. Similarly, we offer extensive experience of compliance with the require-ments of 21 CFR Part 11.

The Siemens approach:• Emphasis on user-friendly products – for safer

operation• High degree of product safety – through maximum

process transparency• Optimal resource efficiency – through innovative

platform concepts• Flexibility – for faster and safer manufacturing

changeover• Increased productivity – with optimal solutions

for the operating phase

Customer benefits:• Fast commissioning, short ramp-up times• Low total cost of ownership (TCO)• Quick return on investment• Continual improvement through innovative service

and support concepts• Traceability to ensure manufacturing quality through

completely integrated production• Maximum compatibility and innovation assuring your

confidence in the future

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Level

Positioning

Liquid analytics

Weighing

Identification

Flow

Gas chromatography

Gas analytics

Pressure

CGA

Temperature

In-situ

Process protection

Software

6

Chemical ActivePharmaceuticalIngredients (Chem APIs)Companies that manufacture Chem APIs operate to

very high quality and safety standards. The handling

of complex chemical reactions in hazardous areas

is routine work in this particular sector. Safety is a

priority – for employees and with respect to product

safety.

The observance of efficient protection measures is essen-tial when handling highly active pharmaceutical ingredi-ents. Staff must be protected from the product while the product must be protected from contamination. A high degree of plant flexibility is often required to facilitate the successive manufacture of several Chem APIs in a batch-ing system. This requires efficient and reliable measure-ments, which not only fulfill hygienic requirements, but also guarantee secure handling in hazardous areas.

STORAGEPowdery ingredients

PREPARATION

STORAGELiquid ingredients

TANK FARM

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Chemical APIs Biological APIs Pharmaceutical manufacturing (solids) Pharmaceutical manufacturing (liquids) Infrastructure

MillFeeder vessel forliquid material

Vessel forfluid intermediate

Vessel forauxiliary material

Condenser

Heating /Cooling

Heating /Cooling

Heating /Cooling

Heating /Cooling

Heating / Cooling

Feeder vessel for dry or disperse intermediate

SYNTHESIS REACTION

Feeder vessel

Crystallizer

Feeder vessel

Reaction vessel

Heating / Cooling

Vacuum

Vacuum

Dryer

Cellular wheelsluice

Centrifuge

Bunker

Cooler

Wetsieve

PURIFICATION & ISOLATION

Heating /Cooling

Cleanroom

Intermediate storage

Secondarymanufacturing

Drysieve

Granulator

Dryer

BinderIntermediates

FINISHING & CONDITIONING

Level Pressure

Process protection CGA

TemperatureFlow

WeighingIdentification

Positioning

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Biological Active Pharmaceutical Ingredients (Bio APIs)Much of the future of the pharmaceutical industry belongs to biotechnologically manufactured active ingredi-

ents. As a rule, Bio APIs are very expensive products with high temperature and shearing sensitivity. They are

also sensitive to pH, pressure, contaminants and the accumulation of waster material, all of which requires a

complex concentration and separation process. Fermentation lies at the heart of the production process for

these substances. The challenge is to create the right grouping of conducive materials, buffers and air / gases

that facilitate the optimum environment for the growth and production of cultures.

The product is harvested and cleaned after fermentation, rendering it usable as a Bio API at a later stage. The proce-dure demands high requirements on hygiene and repro-ducibility. The subsequent downstream process, wherein the desired molecules are separated and purified, also

poses considerable challenges. The requisite investment in plants and equipment is considerable. Precise control and measurement of the fermentation and downstream processes is essential in securing increased reproducibility and uniform consistency.

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Cell bank

Clean room

Clean room

Harvesting vessel

Heating / Cooling

Pulsationdamper

Pulsationdamper

Secondary manufacturing

Heating / Cooling

Heating / Cooling

Mainfermenter

Heating / Cooling

Heating / Cooling

Heating / Cooling

Heating / Cooling

Heating / Cooling

Extracellular

Separator

Mixing / Collecting vessel

Pre-fermenterSpeed

fermenter

Freeze dryerFeeder vesselsFeeder vessels

Capturechromatography

Heat exchangerHeat exchanger

Purificationchromatography

Micro-filtration

Additives

Intracellular

Filter Filter

Liquidproduct

Driedproduct

Cell disruption

Inoculate cabin

Inoculum preparation

Filter

Buffer / Media preparation

Preliminary products

Filter

DISPENSINGPREPARATION FERMENTATION

SEPARATION / HARVEST

PURIFICATION

Level Pressure

Process protection Liquid analytics

TemperatureFlow

WeighingNIR

Positioning

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Pharmaceutical manufacturing (solids)Active Pharmaceutical Ingredients (APIs) must be formulated in such a way that the patient receives the

prescribed dosage. Products are manufactured in a variety of different vectors: tablets, capsules, solutions,

suspensions, emulsions, gels, creams (oil-in-water emulsions), ointments (water-in-oil emulsions) and aerosols

(containing inhalants or substances suitable for topical use).

Maintaining high quality standards under increasing cost pressures characterizes drug manufacturing today. A cen-tral aspect of the design of new process pharmaceutical manufacturing plants and the upgrading of existing ones (in addition to the equipment) is the creation of sanitary zones and installation of concomitant HVAC systems. Many production logistics variables, including the flow of materials and personnel, must also be taken into account.

Projects in drug manufacturing often require the expedi-tious integration of complex technologies in an existing production center. To eliminate manufacturing down-times as much as possible, implementation and assembly typically need to take place during ongoing operations. The successful deployment of such projects requires care-ful planning, excellent industry experience and reliable products.

SolidsStand-alone production units characterize the manufac-ture of solid dosage forms. Each unit operates in accor-dance with pharmaceutical-specific and technical method-ologies that are monitored constantly by means of multiple sensors. All processes must be coordinated in order to maintain optimum flow and meet production safety stipulations.

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Level Pressure

Gas analytics CGA

TemperatureFlow

WeighingIdentification

Positioning

Dryer

Tabletpressing

Counter

Preliminary productsand binder

Air

Dryer

DISPENSING

Air

Pellets

Labeler

Tablets Capsules Powder

BlendingDrysieve

Wetsieve

Pelletizing

Granulator

Coater

Stretch-banding machine

FINISHING

Capsulefilling

PREPARATION &FORMULATION

PACKAGING Blistermachine Dosing

machine

CartonerCheck weigher

Case packer Pelletizer

Washing machine

Loading / Transportation

Pharmaceuticalmanufacturing (liquids)

LiquidsLiquid mixing and liquid blending are two of the most complicated pharmaceutical manufacturing unit opera-tions. The blending of dissimilar fluids, such as oil and water, or the incorporation of solids into the liquid manu-facturing process makes liquid mixing and liquid blending a processing challenge. Siemens equipment, underpinned by technical knowledge, provides exact monitoring of your process, thus ensuring consistent product quality.

❄ ❄

DISPENSING

SYRINGE &DELIVERY DEVICE:Preparation vesselVIAL & AMPOULE:Formulation vesselCREAM & OINTMENT:Water phase vessel

SYRUPE:Sugar melting vessel

PREPARATION & FORMULATION

Transferpump

Heating / Cooling

Filter

Finalsterilefilter

SYRINGE &DELIVERY DEVICE:Holding vesselVIAL & AMPOULE:Collecting vesselCREAM & OINTMENT:Wax phase vesselSYRUPE:Manufacturing vessel

Heating / Cooling

Transferpump

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❄ ❄

Filling

Filling

Filling

FillingAssembly Blister machine

Loading / Transportation

Stoppering

Terminalsterilization(optional) Inspection

Sealing

LabelingPlunger rodassembly

Anti-counter-feiting systemassembly

Stoppering &Cappering

Inspection

Freeze drying

LabelingLabeling

Cartoner Check weigher

Stretch-bandingmachine

Labeler

PelletizerCase packer

SealingLeak

testing

Ampoule closing

Sterilization tunnelfor stoppers

Washing machinefor stoppers

Washingmachine

Sterilizationtunnel

Homo-genizer

Bag manufacturing Port attaching

Storagevessel

Port washing

VIAL & AMPOULEFINISHING

CREAM & OINTMENT FINISHING

VIAL

PACKAGINGDELIVERY DEVICE FINISHING

SYRINGE FINISHING

AMPOULE

Level Pressure Temperature Valve positioningFlow

Liquid analytics IdentificationWeighing

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InfrastructureUtilities are indispensable to efficient pharmaceutical

manufacturing. Their impact on the cost-effectiveness

of a production site is immense. A reliable supply of

purified water, water for injection, and pure steam

must be guaranteed at all times during operation, and

at a consistently high quality. Such quality is also a

prerequisite within the distribution network, twenty-

four hours a day. Intelligent concepts and measure-

ments play a vital part in the reliable delivery of this

important resource.

At the end of the production process, wastewater and flue gases are generated, especially in the manufacture of APIs. Emissions can be minimized in production but may not be entirely avoidable. Therefore, the remaining off-gases and effluent outflows must be treated safely and cost-effectively in order to meet allowable discharge limits while maintaining the availability of the entire manufac-turing site and ensuring environmental protection.

POWDERY INGREDIENTS

LIQUID INGREDIENTS

HEATING / COOLING UNIT

Heating

from process

Exhaust air

Cooling

toapparatusapparatus

Cooling

Hea-ting / Cooling

CIP / SIP

base acid finalrinse

VACUUMUNIT

TANK FARM

STORAGE

PACKAGE UNITS

Level PressureFlow

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SOLVENT RECOVERY EXHAUST AIR PROCESSING

PURE STEAM WASTE WATER TREATMENT

COMPENDIAL WATER REVERSE OSMOSIS

COMPENDIAL WATER STILLS

COMPENDIALWATERIONEXCHANGER

Exhaust air Exhaustair

Puresteam

Disinfection / de-contamination

Exhaustairprocess-ing

Ash removal

Bunker

KilnSlag removal

HAZARDOUS WASTEINCINERATOR

Water

Post-clarification

Heating

Sludge treatment

After-burnerchamber

Heatrecovery

Conden-sate

WFI

Biologicalstage

Incinerator

Quencher H2O scrubber NaOH scrubber

Chimneystack

Waste watertreatment

Slagremoval

Wastewater

Pre-clarification

Exhaust gas

Cooling water

Condensatetank

Heatproduct

Heatingsteam

Condensate

Slurry

Module I

Module II

Concentrate

Permeate

Pump

Carbonateremoval

Filter

CaCO3

Cationexchanger

Cooling

WFIHeating

Column Column Condenser

Cooler

Anionexchanger

Residualionexchanger

Filter

Feed

Feed

Supply

Column

UTILITIES

Pressure Temperature

Gas chromatography

Valve positioning

CGA

Liquid analytics

Identification

Weighing

In-situ

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PressurePrecise measurement combined with hygienic design

make the SITRANS P300 ideal for applications in the

pharmaceutical industry. The precision of the device

enables manufacturers to optimize efficiency and in-

crease plant productivity. The stainless steel housing

and front flush diaphragm guarantee a dead space-

free measurement and offer easy cleaning.

SITRANS P300 pressure transmitterThe P300 is built to withstand temperatures of up to150 °C (302 °F). It can also be used with a temperature decoupler in situations where even higher temperatures (up to 250 °C / 482 °F) are encountered. Unlike the decou-pler, it does not affect accuracy. Reliability is thus assured even in very hot conditions.

The SITRANS P300 offers drift-free usage over a very long period even where continuous sanitization is in place, pro-viding the pharmaceutical industry with a new dimension. The construction and design of this transmitter is in accor-dance with the rules and standards of EHEDG (European Hygienic Engineering and Design Group) and 3 A (Sanitary Standards, Inc.).

SITRANS P300 highlights• A digital pressure transmitter offering ‘three push-

button’ handling and extensive diagnostics as well as simulation functions

• The stainless steel housing and measuring cell is designed according to hygienic requirements

• Suitable for CIP and SIP processes• A broad range of communication options (HART®,

PROFIBUS PA, FOUNDATION Fieldbus) combine with SIMATIC PDM to ensure easy and seamless integration in the world of SIMATIC

• Exact and stable measurements over a long period, e. g. a reference accuracy of < 0.075 % with a long-term stability up to 0.125 % in five years

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Pressure Temperature Valve positioning Weighing Software

TemperatureSiemens offers many differently designed resistance

thermometers and thermocouples to the pharmaceuti-

cal industry. All these sensors are equipped with the

process connection systems required in the pharma-

ceutical industry and are designed in accordance with

hygiene requirements. Construction and materials

meet FDA, EHEDG and 3 A standards.

SITRANS T resistance thermometersSiemens temperature sensors can be installed as clamp-ons (measuring temperature without media contact). These clamp-on resistance thermometers can be easily retrofitted without interfering with operations. Because it is clamped on, the device does not intrude in the process in any way or disrupt the flow. The temperature sensor with pipe collar can be used for temperature monitoring, particularly for sterile applications. Temperature measure-ment is possible following simple, fast assembly on any existing pipeline system. It is not necessary to interrupt the pipeline or to carry out welding. Assembly on the pipeline is simply implemented by adapting the two halves of the collar. The device can also be supplied with an integral transmitter as an option.

Resistance thermometer highlights• Temperature measurement free of dead space• Can be retrofitted onto existing pipelines• Matches all common nominal pipe diameters• Optimum temperature measurement using

metallic pressing system• Insulating collar made of temperature-resistant

plastic, easy to clean• Measuring range –20 to +200 °C (–4 to +392 °F)• Replaceable Pt 100 measuring insert; thus no changes

in measuring setup• Calibration possible• Transmitter can be integrated (4 to 20 mA, HART®,

FOUNDATION Fieldbus or PROFIBUS PA)

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Valve positioningNearly all pharmaceutical processes in primary produc-

tion are deployed by means of controlled valves. Next

to many other additional features the SIPART PS2 pro-

vides precise valve monitoring and diagnostics of

events in case of error.

SIPART PS2 valve positionerNext to advantages like an easy installation and quick commissioning the SIPART PS 2 is equipped with compre-hensive functionalities, and delivers diagnostic data on itself, its environment and the valve and actuator. With these premium diagnostics, this positioner sets the stan-dards for cost efficiency, reduces maintenance require-ments in the plant, guarantees safe process control, and provides high functional safety in emergency situation. The diagnostics package that is included in every device as standard without additional costs includes functions for pneumatic leaks, valve wear, static friction, stiffness and much more. Additionally, the SIPART PS 2 ensures with a regular partial stroke test that ESD (emergency shutdown) valves and other open / close automated valves remain movable in the event of an emergency.

All diagnostic features at a glance:• Alarm status based on NAMUR NE107• Partial stroke test for open / close and control valves• Pneumatic leaks• Stiffness of a valve• Stiction of the packing• Wear of, deposits or caking on the valve seat or plug• Failure of the valve or actuator shaft• Trend diagrams, Histograms• Stroke counter for fitting, Direction reversal counter,

operating hours counter• Deadband and temperature measurement

SIPART PS2 highlights• The No. 1 among smart electropneumatic positioners• Standard Makrolon® enclosure to IP66 / NEMA4x

protection, with optional aluminium or stainlesssteel enclosure

• Versions with external non-contacting travel sensors• High flexibility in the stroke range from 3 to 200 mm

(0.1 to 7.9 inch) or more• Communication via PROFIBUS PA,

FOUNDATION Fieldbus or HART

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WeighingWeighing and proportioning is a central aspect of suc-

cessful pharmaceutical production. Our high-quality

and competitive weighing products offer users com-

plete accuracy in the process and optimum productivi-

ty in the plant. In other words, absolute reliability and

the highest production speed at the same time. With

Siemens, you get competence and comprehensive ex-

pertise in both automation and weighing technology.

Siemens has been a leader in both fields for many

years – worldwide.

SIWAREX weighing technologyBatch, loss-in-weight, bagging and check weighers are only a part of the areas for state-of-the-art weighing tech-nology. For all kinds of applications, SIWAREX offers a wide range of weighing electronics as well as load cells and corresponding mounting accessories. All components are suitable for usage in environments with highest requirements in hygiene.

The direct integration of SIWAREX into SIMATIC enables a continuous and open solution for the demands of weigh-ing tasks within the automation structure.

Whether SIWAREX is used central in SIMATIC or local by using PROFIBUS or PROFINET, the integration stays contin-uous and flexible for expansions. Interface standards, integrated functions, standard tools and well-prepared ‘ready-to-use’ applications support a quick and cost-effec-tive configuration.

SIWAREX highlights• Provision of all typically needed weighing modes• Expandable by further weighing modules at any time• Calibration, parameterization and operation via

standard HMI or Windows tool• Legal-for-trade approval• Integration into control cabinet avoids contact with

the product• Load cells and mounting accessories in stainless steel• Efficient communication and data handling due to

cross-linking to PROFIBUS or PROFINET• Diagnostics and maintenance possible via teleservice• Accuracy of 0.1mg in combination with digital load

cells

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SoftwareWith different communication protocols and the

necessary software, Siemens offers the right tools to

integrate its process instruments and analyzers

into the world of process automation.

SIMATIC PDM(Process Device Manager)SIMATIC PDM (Process Device Manager) is a cross-vendor tool for configuration, parameterization, commissioning and diagnostics of intelligent field devices based on inter-national EDD standard (Electronic Device Description; IEC 6 / 804-2). It ensures seamless integration for the instru-mentation and analytics that Siemens offer.

The following core functions of SIMATIC PDM serve to control devices and processes utilized inprocess automation• Setting and modifying of parameters• Parameter plausibility check• Archiving of parameter sets in a consistent database• Documentation of parameter sets• Comparison of parameter sets• Calibration support• Loop tests• Online diagnostics

Communication with process devices uses the HART® protocol, PROFIBUS or other protocols.

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Pressuremeasurement

Temperaturemeasurement Weighing

SITRANS P SITRANS T SIWAREX PLC basedweighing systems

SITRANS P offers a complete range of instruments for measuring relative, differ-ential and absolute pressure. The SITRANS P300 has a hygienic stainless steel housing with laser-etched nameplate. The SITRANS P300 meets the requirements of EHEDG, FDA and 3 A. Cleaning and steriliza-tion are standard practice.

The clamp-on thermometer offers quick and highly accurate measurement without disturbance of the process and provides easy recalibration. Equipped with our unique SITRANS TH or TR transmitters, we offer the turnkey solution. Classical wetted temperature sensors complete the temperature measurement portfolio.

Provide optimum integration into the automa-tion structure of the process. Ideal forusers familiar with the SIMATIC S7 or PCS 7 process control system and components.

Flowmeasurement

Electromagnetic flowmeters Coriolis flowmeters Clamp-on ultrasonic flowmeters

Siemens full series of flowmeters for liquids and slurries gives a wide range of customer-specified process connections.

One of the most accurate flow measurement technologies, measuring true mass flow unaffected by variations in pressure, temperature, density, electrical conductivity and viscosity. It is a multivariable device delivering reliable information on mass flow, volume flow, temperature, density and concentration (e. g. Brix or Baume). SITRANS FC430 is the market’s most compact Coriolis solution. The small size facilitates installation and replacement, and makes it possible to fit multiple units into tight spaces.

Ultrasonic clamp-on flow meters provide highly accurate liquid flow measurement. The exter-nal transducers can quickly and easily be installed on the outside of pipes ranging from DN 6 to DN 9140 (0.25” to 360”) in size. And with no need to cut the pipe or stop the flow, maintenance is minimal.

Process Instrumentationand Analytics product rangeSiemens offers the most comprehensive product range for the pharmaceutical industry and has a solution

for even the most difficult measurements.

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Levelmeasurement

Radar Ultrasonic Point level

Liquids level measurement Solids level measurement SITRANS LG200

SITRANS LR200 and SITRANS LR250 offer continuousmonitoring of liquids and slurries in storage / process vessels. SITRANS LR250 is available with fully resistive PVDF antenna design for use in sanitary environments.

SITRANS LR260 and SITRANS LR560 offer continuous monitoring of solids for a variety of silos or storage bins.

2-wire, guided wave radar transmitter for short- to medium-range level, level / interface, and volume measurement of liquids andsolids.

Positioning Process Protection Remote monitoringand displays Process Analytics

SIPART PS2 Motion sensors Acoustic monitoring SITRANS RD100 / 200 / 500

Positioner for linear and rotary actu-ators. Particularly flexible stroke range, intelligent diagnostics and communicates either via HART,PROFIBUS PA or Foundation Fieldbus.

Most MFA 4p motion sensing probes as well as the Millpulse 600 can be mounted up to 100 mm (4”) from the ferrous target, reducing the chance of damage to the probe and the equipment. SITRANS WM100 zero-speed alarm switch provides equip-ment protection even in harsh conditions.

SITRANS AS100 detects changes in high-frequency sound waves result-ing from particle impacts on equip-ment. In combination with SITRANS CU02 alarm control unit, it detects and reacts instantly to changes in solids flow.

SITRANS RD100 / 200 are remotedisplays for process instrumentation. SITRANS RD500 provides integrated web access, alarm event handling, and data capture.

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Levelmeasurement

Radar Ultrasonic Point level

SITRANS Probe LU Level controllers andtransducers Point level switches

2-wire, loop-powered ultrasonic trans-mitter for level, volume, and flow moni-toring of liquids in storage vessels, sim-ple process vessels and open channels.

SITRANS LUT400 can be used in a variety of applications in combination with Echomax transducers.

SITRANS LPS200, SITRANS LVS200, Pointek CLS200, SITRANS LVL200 and Pointek ULS200 offer a range of level detection options for liquids and solids applications.

Positioning Process Protection Remote monitoringand displays Process Analytics

Continuous gas analysis Process gas chromatography Tuneable diode laser spectrometer (TDLS)

A practical combination of the ULTRAMAT 6 and OXYMAT 6 analyzers in a single enclosure. The ULTRAMAT channel measures CO, CO2, NO, SO2

and NH3 as well as CH4 and other hydrocarbons. The OXYMAT channel measures the oxygen content of gas. Cleanable sample cells and optional corrosion-resistant materials in the gas path make measurement of highly corrosive sample gases possible.

The MicroSAM is a miniaturized process gas chromatograph. The design particularly enables installation close to the process. Ideal for the analysis of O2, N2, CO2 and water in fermenting processes or alcohols in nitrogen for vacuum drying plants. The MAXUM edition II is a universal process gas chromatograph for flexible process applications with a wide variety of analytical options. Ideal for the determination of halogenated hydrocarbons, simultaneous determination of chlorinated hydrocar-bons, aromatics and alcohols in water and wastewater monitoring with PGC and stripper.

Fast in-situ gas analyzers for process control. Innovative solution using laser absorption spectroscopy to measure gas concentrations within the main process.

Process Instrumentation and Analytics product range

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Control Level

Management Level

Operations Level SIMATIC PCS 7Operation System

SIMATIC IT

Maintenance / Asset Management

EngineeringStation

MES – Manufacturing Execution Systems

ERP – Enterprise Resource Planning

SINUMERIKComputer Numeric Control

SIMATIC PCS 7AutomationSystems

SIMOTIONMotion Control

SIMATIC NETIndustrialCommunication

SIMATIC IdentIndustrial Identifi cation

Process Instrumentation

Field Level

TotallyIntegratedAutomation

HART

PROFIBUS PA

TIA Portal

IO-Link

PLM – Product Lifecycle Management • Product Design• Production Planning and Simulation• Data Management

Totally Integrated Automation

Products from the controller level to the field levelWith Totally Integrated Automation (TIA), Siemens is the only provider of an end-to-end integrated portfolio of products and systems for the automation of the entire production workflow. From the goods receiving area to the finished goods warehouse.

Totally Integrated Automation reduces the complexity of the automation solution and enables what really counts: the practical combination of optimally coordinated indi-vidual components – without interface problems.

Totally Integrated Automation integrates not only the pro-duction process but all parts of the company – from the field level to the management level. The result: a perfectly coordinated overall concept that enables higher productivity.

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Example: SIMATIC PCS 7. The innovative process control system offers numerous options for connecting I / Os as well as for sending and receiving process signals via sensors and actuators.

COMOS

EnergyManagement

Plant Engineering

SIMATIC WinCCSCADA-System

Ethernet

SIRIUS Industrial ControlsSIMATIC ControllersModular / PC-based

SIMATIC HMIHuman Machine Interface

Industrial Ethernet

Low-Voltage DistributionSIMATIC Distributed I / O SINAMICS Drive Systems

TotallyIntegratedPower

PROFINET

Industrial Ethernet

PROFIBUS

AS-Interface

KNX GAMMA instabus

SIMOTICS Motors

Totally Integrated Automation Industrial Identification Services and support

26

Industrial IdentificationToday, efficient tracking and tracing plays an increasingly important role in all industries. Legal requirements

and rising demands for process quality have made full traceability with the perfect identification system virtual-

ly indispensable. The best answer for addressing this challenge: SIMATIC Ident, our comprehensive industrial

identification portfolio, which offers complete documented histories of products, components and systems. With

industrial identification, each product leaves a digital trace that can be traced and documented all the way back

through its individual component parts.

Industrial identification for sustainablyefficient processesMachine-readable, automated and contactless identifica-tion systems synchronize virtual data streams in the IT systems with the actual flow of goods and ensure maxi-mum transparency – not only in production processes, but also in the external logistics processes. Advantages are created along the entire supply chain: quality require-ments can be reliably met, production can be more flexi-bly structured, the number of manual operations reduced and potential sources of faults recognized and removed instantly. In any case, SIMATIC Ident will help you benefit from greater efficiency in logistics, material management, production and service.

Radio or optical – the application decidesDepending on the application in question, one of two main technologies is used in the industrial environment: Radio frequency identification (RFID) based on radio waves or optical code-reading systems for the recognition of 1D codes (barcodes), 2D codes such as data matrix codes (DMC) and optical character recognition (OCR) of plain text. These extremely reliable technologies ensure the gap-free traceability of products and components along the entire manufacturing, purchasing or dispatch process. By choosing SIMATIC Ident, you are opting for an integrated portfolio for industrial identification – ranging from code readers and RFID systems to the integration software.

Enterprise ResourcePlanning (ERP)

RS232/RS422

ANT 18

RF630R RF640R

RF620A

SCALANCEX108PoE

RF180C/RF182C(TCP/IP)

RF220R RF340R RF240RMV440RF210RRF350R

ASM 456/RF160C

Industrial Ethernet

Ethernet

IO-Link

Industrial EthernetPROFINET/Industrial Ethernet

PROFIBUS

ET 200pro/RF170CS7-300/ASM 475

Manufacturing Execution Systems (MES)

MV420

RFID Middleware

Management level

Control levelSIMATIC connection Connection to PC

Acquisition level

Reader

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Services and supportSiemens offers field-proven concepts for process instrumentation and analytics from a single source, providing

you with development continuity and a high level of security.

Our services range from consulting and engineering, connection to the control system and comprehensive after-sales services:

• System and schedule planning• Complete design planning and engineering of

the field devices• Consultation on the selection of process instruments

and analytics• System documentation• Installation, testing and commissioning• Comprehensive after-sales service

Service around the worldPlants must function reliably around the clock. Efficient and effective process instrumentation and analytics are an indispensable prerequisite to this end. You also need to be certain of fast and competent service from your supplier.Siemens is a global company that reacts locally. Whether you require consulting, quick delivery or installation of new devices, the Siemens network of specialists is avail-able to you around the world, whatever your location.

Service around the clockOur online support system offers rapid, comprehensive assistance regardless of time or location. From product support to service information, the online support of Siemens Industry Automation and Drive Technologies is your first choice – around the clock, 365 days a year.

www.siemens.com / automation / service&support

Totally Integrated Automation Industrial Identification Services and support

The information provided in this brochure contains merelygeneral descriptions or characteristics of performance whichin case of actual use do not always apply as described or whichmay change as a result of further development of the prod-ucts. An obligation to provide the respective characteristicsshall only exist if expressly agreed in the terms of contract.

All product designations may be trademarks or product namesof Siemens AG or supplier companies whose use by thirdparties for their own purposes could violate the rights of theowners.

Subject to change without prior notice 06 / 12Order No.: E20001-A190-P780-X-7600DISPO 27900o2e MI.SC.IM.XXXX.52.2.06WS 06122.0Printed in Germany© Siemens AG 2012

Siemens AGIndustry SectorSensors and Communication76181 KARLSRUHEGERMANY

More information:www.siemens.com / sensors / pharma

Process Instrumentation and Analytics - Industrial...

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