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T e r r y W h i t e C h e m m a r t p h a r m a c i s t s t r a i n i n g

P r o b i o t i c sP r o d u c t T r a i n i n g

For professional training onlyFor professional training only

Brand Overview

BioCeuticals is an easy recommendation for Pharmacists to make!• Supported by strong scientific research

• Highly trained and diverse technical support team to provide details on interactions and contraindications

• Patients will come back for more!

• Features clinically trialled and proven ingredients

• Adheres to stringent quality control procedures

• Uses sustainable herbal ingredients

• Uses evidence-based standardised extracts, where possible

• Contains no artificial colours, flavours or sweeteners

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Who is BioCeuticals?

Australia’s #1 provider of practitioner only

nutritional and therapeutic supplements

1. Unique & Effective Formulations• Developed by our Scientific Advisory Committee

2. Compliance• Easy to administer and affordable

3. Evidence• Ongoing science and research

4. Conscience • Sustainable, safe and high quality ingredients

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1. IM Gateway

• Your ‘eMIMS’ for natural medicines.

• Found under the ‘education tab’ on our website.

2. TEB’s, Fliers and Product Manual

• Contains all referenced info about our products.

3. Tech Support

• Contact Tech Support for interactions and research.

4. Your Reps

• Your trainers and range advisors

• Makes plans to develop and grow your range to suit YOUR business

5. Seminars and Symposiums

• These take you to ‘the next level’.

• Diverse, applicable, mind-blowing!

• Contribute towards CPD

• 48 group 2 points confirmed!!!!

Five Keys to Success with BioCeuticals

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Intestinal microbiota

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With over 400 microbial species

inhabiting our gut, species of

lactobacillus and bifidobacterium

are prominent members of the

normal flora of the GIT


When to take probiotics

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• Our probiotic strains are tested to ensure they can withstand the pH of the stomach when food is present.

• Most living organisms cannot survive a pH as low as 1.8; this is why there is very minimal colonisation within the stomach. Only extremely robust strains such as Helicobacter pylori survive such acidic environments.

• Probiotics should be taken with food

• This is because the pH of an empty stomach is somewhere between 1.8 and 2.6; when you eat, the presence of food has a neutralising effect, increasing the pH to between 3.5 and 4.2, meaning it is nearly 100 times less acidic.

• Probiotic bacteria are much more likely to survive in this less acidic environment where they remain for approximately two hours awaiting movement into the small intestine.


Stability data

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Lactobacillus rhamnosus (CUL 63) 15.55 billion CFU

Lactobacillus casei (CUL 07) 9.45 billion CFU

Lactobacillus acidophilus (CUL 21 + CUL 60)

7.4 billion CFU

Lactobacillus plantarum (CUL 66) 3.15 billion CFU

Lactobacillus fermentum (CUL 67) 1.35 billion CFU

Bifidobacterium animals subsp. lactis(CUL 34)

4.05 billion CFU

Bifidobacterium breve (CUL 69) 1.35 billion CFU

Bifidobacterium bifidum (CUL 20) 450 million CFU

Streptococcus thermophilus (CUL 68) 2.25 billion CFU

Each capsule contains:

*CFU = colony forming units

Available in 30 and 60 capsulesTake 1-2 capsules daily or as directed by your healthcare practitioner.

UltraBiotic 45Multistrain Probiotic, 45 Billion CFU per Capsule


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• High-strength, broad-spectrum probiotic

• Dairy free

• Contains bacteria for small and large bowel , as well as

urogenital tract

• Maintenance of healthy intestinal flora and healthy

digestive function

• Nutritional support for a normal healthy immune system

• May support against the immunosuppressive effects of

intense and endurance exercise

• Temporary symptomatic relief of medically diagnosed IBS

UltraBiotic 45Multistrain Probiotic, 45 Billion CFU per Capsule


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Lactobacillus acidophilus (CUL 21 + CUL 60)

30 billion CFU

Bifidobacterium animals subsp. lactis(CUL 34)

14.25 billion CFU



*CFU = colony forming units

Available in 30 capsulesTake 1-2 capsules daily or as directed by your healthcare practitioner.

UltraBiotic IBSHeat-Stable Clinically Trialled Probiotic


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• An evidence-based blend, known as Lab4 , which may help

promote the maintenance of healthy intestinal flora

• Clinically demonstrated for symptomatic relief of

medically diagnosed IBS ; i.e. reducing the number of

days of abdominal pain

• May assist with the maintenance of normal healthy

intestinal flora during and following antibiotic us e

• Nutritional support for normal healthy immune function

• Each capsule provides 25 billion CFU when kept at room

temperature or 45 billion CFU when refrigerated

• Dairy-free and vegetarian friendly



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52 participants with IBS, given 25 billion CFUs of Lab4 or placebo for 8 weeks, had temporary relief of the symptoms within 2-6 weeks

Daily supplementation with Lab4 probiotics during and after antibiotic therapy reduces the extent of disruption to intestinal microbiota as well as incidence and total numbers of antibiotic-resistant strains in the regrowth population.



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Bifidobacterium bifidum (W28) 135 million CFU

Lactobacillus acidophilus (W70) 270 million CFU

Lactobacillus brevis (W63) 337.5 million CFU

Lactobacillus helveticus (W74) 135 million CFU

Lactobacillus plantarum (W21) 337.5 million CFU

Lactobacillus salivarius subsp. salivarius (W24) 135 million CFU

Lactoferrin 1.98mg


Available in 5 capsulesInsert one capsule into the vagina once daily before sleeping. Wet capsule before use, if required, and insert immediately. Use capsules for 5 consecutive days or as directed by your healthcare practitioner.

UltraBiotic FEMI+Multistrain Probiotic Pessary with Lactoferrin


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• Contains 1.35 billion CFU of a combination of 6 strains of

bacteria plus lactoferrin

• A convenient pessary for local delivery

• The healthy vaginal microbiota is dominated by

lactobacillus species

• Administration of L. plantarum vaginally demonstrated an

increase in vaginal lactobacilli numbers

• Shelf-stable

UltraBiotic FEMI+Multistrain Probiotic Pessary with Lactoferrin


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Each 5g sachet contains:

Bifidobacterium bifidum (Bb-06) 5 billion CFU

Bifidobacterium animals subsp. lactis (BI-04)

220 billion CFU

Bifidobacterium lactis (HN019) 35 billion CFU

Bifidobacterium longum (Bi-05) 5 billion CFU

Lactobacillus acidophilus (La-14) 50 billion CFU

Lactobacillus brevis (Lbr-35) 15 billion CFU

Lactobacillus casei (Lc-11) 10 billion CFU

Lactobacillus gasseri (Lg-36) 15 billion CFU

Lactobacillus paracasei (Lpc-37) 50 billion CFU

Lactobacillus plantarum (Lp-115) 30 billion CFU

Lactobacillus rhamnosus (HN001) 10 billion CFU

Lactobacillus rhamnosus (Lr-32) 5 billion CFU

Lactobacillus salivarius (Ls-33) 40 billion CFU

Streptococcus thermophilus (St-21) 10 billion CFUAvailable in 7 and 14 sachets

Mix one sachet (5g) into 100mL of water or juice. Consume once daily for 7 or 14 days or as directed by your healthcare practitioner.

UltraBiotic 500Super Strength, 14 Strain Probiotic


• High strength, intensive probiotic

• 14 probiotic strains providing 500 billion CFU

• Convenient one-a-day dose

• May help to maintain intestinal microbiota when

taken during and after antibiotic therapy

• Aids digestion and supports digestive health

• Supports a normal healthy immune system

• Halal and Kosher certified

• Dairy free

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UltraBiotic 500Super Strength, 14 Strain Probiotic


Each vegetarian capsule contains:

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Lactobacillus fermentum (CUL 67) 5 billion CFU

Lactobacillus gasseri (Lg-36) 5 billion CFU

Lactobacillus plantarum (CUL 66) 5 billion CFU

Lactobacillus rhamnosus (CUL 63) 5 billion CFU

Lactobacillus salivarius subsp. salivarius (CUL 61)

5 billion CFU

Bifidobacterum bifidum (CUL 20) 5 billion CFU

Bifidobacterum animals subsp. lactis (CUL 34) 5 billion CFU*CFU = colony forming units

Available in 30 and 60 capsulesTake 1-2 capsules daily or as directed by your healthcare practitioner. Take 1 capsule daily for maintenance of a healthy digestive, urogenital and immune system during pregnancy. Take 2 capsules daily to support a positive effect on infant health, including a decrease in the incidence of mild atopic dermatitis/allergy symptoms in your child in their first years of life.

UltraBiotic Pregnancy CarePre- and Postnatal Probiotic Support


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• Innovative , high-dose, broad-spectrum probiotic blend

• 7 probiotic strains, 35 billion CFU

• Based on ground-breaking research

• When taken during pregnancy and breastfeeding, may:

– reduce risk of maternal genitourinary conditions

– relieve medically diagnosed lactational mastitis and

GIT disturbances

– influence infant growth patterns , microbiota

development and decreasing risk of atopic eczema

• In conjunction with dietary counselling, may help to

maintain normal healthy glucose levels in women who

have a normal blood glucose level during and after

pregnancy



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Translocation of probiotics


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BMC Infect Dis. 2008 Apr 18;8:51. doi: 10.1186/1471-2334-8-51.

PCR-DGGE assessment of the bacterial diversity of b reast milk in women with lactational infectious mastitis.Delgado S, Arroyo R, Martín R, Rodríguez JM.

Source

Dpt. Nutrición, Bromatología y Tecnología de los Alimentos, Universidad Complutense de Madrid, 28040 Madrid, Spain. [email protected]:

Infectious mastitis is a common condition during lactation and in fact, represents one of the main causes leading to a precocious weaning. The number of studies dealing with lactational mastitis is low and, up to now, the etiological diagnosis is frequently made on the basis of unspecific clinical signs. The aim of this study was to investigate the microbial diversity of breast milk in 20 women with lactational mastitis employing culture-dependent and culture-independent (PCR-DGGE) approaches.METHODS:

Breast milk samples were cultured in different media to investigate the presence of bacteria and/or yeasts, and a total of 149 representative isolates were identified to the species level by 16S rRNA gene PCR sequencing. The microorganisms recovered were compared with those found by PCR-DGGE analysis. To identify the DGGE profiles two reference markers of different microbial species were constructed. Sequence analysis of unknown bands was also performed.RESULTS:

Staphylococci were the dominant bacterial group and Staphylococcus epidermidis was the dominant species. In a lower number of samples, other bacteria (mainly streptococci and a few gram-negative species) were also identified. Globally, PCR-DGGE results showed a good correlation with those obtained by culture-based methods. However, although DNA bands corresponding to different lactic acid bacteria were detected, such bacteria could not be isolated from the milk samples.CONCLUSION:

Staphylococci seem to be the main etiological agents of human lactational mastitis. The combined use of culture and molecular techniques allowed a better characterization of the bacterial diversity in milk from women suffering from infectious mastitis. Our results suggest that this condition could be the result of a

Mastitis may be the result of a dysbiotic process where some bacterial species usually present in human milk outgrow (staphylococci) while others disappear (lactobacilli or lactococci).

Women with mastitis received L. salivarius and L. gasseri. After 14 days, the probiotic treatment group showed no signs of lactational mastitis, whereas the condition persisted in those of the control group.

352 women with lactational mastitis were treated with L. salivarius or L. fermentum. Treatment with both strains were more effective than antibiotics .



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Energy 5.86kJ (1.4Cal)

Protein 0g

Fat (total) 0g

Carbohydrates (total) 1.9g

Carbohydrates (sugars) 852mg

Dietary fibre (inulin) 1g

Bifidobacterium lactis (CUL 34) 1 billion CFU

Bifidobacterium breve (CUL 69) 1 billion CFU

Bifidobacterium bifidum (CUL 20) 1 billion CFU

Lactobacillus rhamnosus (CUL 63) 500 million CFU

Lactobacillus fermentum (CUL 67) 500 million CFU

Each 2g serving contains:*

*Based on average amountsCFU = colony forming units

Available in 60g and 100g net powderAdd up to 2g of powder (one rounded scoop [enclosed] supplies 1g) to liquid or solid foods. Consume once or twice daily.

Ingredients: inulin, maltodextrin, B. lactis, L. fermentum, antioxidant (ascorbic acid), L. rhamnosus, B. breve, B. bifidum.

BabyBiotic 0+yrs ®

Gastrointestinal Microflora Support


• Dairy-free probiotic powder, designed to nurture healthy

GI microflora in neonates, infants and children

• Combines 3 of the most common species of

bifidobacteria present in the GIT of healthy breastfed

newborns and infants

• Promotes the growth and development of beneficial

microflora in the infant intestinal tract

• Inulin , derived from chicory, which acts as a natural fuel

for good bacteria, has been shown to encourage the

growth of healthy GI flora in babies and young children

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BabyBiotic 0+yrs ®

Gastrointestinal Microflora Support

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Each 1.1g serve contains:Energy 12.6kJ (3Cal)

Protein 0g

Fat (total) 0g

Fat (saturated) 0g

Carbohydrates (total) 1g

Carbohydrates (sugars) 0.5g

Dietary fibre 0.6g

Sodium 0.4mg

Galacto-oligosaccharides 450mg

Fructo-oligosaccharides 100mg


Bifidobacterium animalis subsp. lactis (CUL34) 2.38 billion CFU

Lactobacillus salivarius spp. salivarius (CUL61) 6.25 billion CFU

Lactobacillus paracasei (CUL 08) 1.25 billion CFU

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UltraBiotic Infant Formula CompanionProbiotics for Formula-Fed Babies


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• Provides the Lab4b combination of probiotics used in the

Swansea Study

• Specifically for use in newborns and young children

• Bifidobacteria and lactobacili are normal components of

the intestinal flora of breast-fed infants , whereas other

organisms predominate in bottle-fed infants

• Probiotics are involved in normal digestion and intestinal

function

• Also contains the prebiotics galacto-oligosaccharide

(GOS) and fructo-oligosaccharide (FOS)

• Suitable for vegetarians



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• GOS and FOS

- Galacto-oligosaccharides (GOS) and fructo-

oligosaccharides (FOS) are found in breast milk

and are dairy-derived

- FOS acts as a prebiotic food for bifidobacteria

• Serving suggestions

- Add 1.1g of powder (one heaped scoop [enclosed])

per day to infant formula after it has cooled

- Or apply the powder directly into the baby’s mouth by

applying to a clean finger and letting the baby suck,

continuing until the scoopful has been consumed



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• A non-pathogenic biotherapeutic probiotic agent that

supports the establishment of friendly bacteria in

the GIT

• Increases production of secretory IgA (slgA), short-

chain fatty acids and the activity of the brush border

disaccharide digestive enzymes

• Discourages the growth of unfriendly micro-

organisms and reduces digestive inflammatory

mediators

• Heat stable (does not require refrigeration ); ideal for

travelling

SB Floractiv ®

The Original Saccharomyces boulardii Supplement


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Mechanisms of action


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• May assist in the temporary relief of symptoms associated with medically diagnosed irritable bowel syndrome (IBS), including bloating, flatulence and digestive discomfort

• May provide relief of symptoms of traveller's diarrhoea

• Aids digestion

• Provides relief of the symptoms, pain and discomfort of gastritis

• For the symptomatic relief of non-specific dyspepsia

• Not affected by antibiotics and may offer relief of symptoms of antibiotic-associated diarrhoea and candidiasis

SB Floractiv ®



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Safety

• Clinically trialled without any serious side effects.

• Avoid by those with true yeast allergy.

• No clinical studies conducted on SB in pregnancy.

• Not recommended in conjunction with prescription anti-

fungals.

• Contraindicated in ruptured or perforated colon after

surgery.

• Caution when prescribing to immunocompromised

individuals on IV lines.

SB FlorActiv ®



Medicine & Chirurgie. Digestive 1976 5(6):401-406

Controlled double blind clinical trials of Saccharomyces boulardii - multicenter study involving 25 physicians and 388 cases.Adam M et al

Multi-centred, randomised placebo double blind trial.Saccharomyces boulardii shown to be effective against antibiotic-associated candidiasis .

Significant decrease in the incidence of diarrhoea in patients receiving Saccharomyces boulardii. No side effects reported .

Reduce recurrence of C. difficile diarrhoea and colitis . No further recurrences of diarrhoea in 85% of subjects

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Human clinical study: 250mg QID for 2 weeks showed increases in specific activity of disaccharidase enzymes.

SB Floractiv ®


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