Principles and Practice of Fertility Preservation edited by Jacques Donnez and S Samuel Kim

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2012;14:E1 The Obstetrician & Gynaecologist http://onlinetog.org Book reviews Book review Principles and Practice of Fertility Preservation Editors Jacques Donnez and S Samuel Kim This textbook brings together experts involved in all aspects of fertility preservation. The literature regarding assisted reproduction, surgery, chemotherapy and radiotherapy, as well as non-cancer-related topics, is extensively reviewed. A wide variety of opinion is sought, mainly from Europe and North America. The book is divided into ten sections and starts with an excellent three-chapter introduction to the history of assisted conception, the effects of radiotherapy and chemotherapy on reproduction and the effects of treatments for non-cancerous conditions. Section two focuses on cancer biology, epidemiology and treatment; section three on reproductive biology and cryobiology, demonstrating various methods of tissue preservation. A section discussing fertility preservation strategies in the male follows. This includes analysis of the effectiveness of hormonal suppression, cryopreservation and transplantation of cryopreserved spermatozoa, spermatogonia and testicular tissue. A chapter is also reserved for the reproductive implications of the use of donor sperm. Medical and surgical strategies for the preservation of fertility in the female are reviewed comprehensively in three chapters, which include explanations of the rationale for the use of GnRH agonists with chemotherapy. Surgery for fertility preservation in both cervical and ovarian cancer, including the techniques of ovarian transposition and trachelectomy, is reviewed comprehensively. Assisted reproduction techniques such as embryo and oocyte cryopreservation and vitrification are also explored in some detail. It is unfortunate that in this otherwise outstanding publication the chapters concerning the preservation of female fertility do not include a discussion of the management of early endometrial cancer in young women. Section seven of the book deals with the management of ovarian tissue and the whole ovary in terms of preservation and transplantation, while section eight discusses how follicles can be matured in vitro. The penultimate section deals with the future, including the use of pluripotent stem cells and the rather fanciful, but nevertheless exciting, prospect of an artificial ovary. The author points out that this is the first publication on the subject. The final section deals with the all-important subject of ethical, legal and religious considerations, including the psychological impact of a cancer diagnosis. There are few areas of the book that I can criticise. Indeed, I believe my review cannot do it justice: the expertise involved is so wide-ranging that no individual reviewer would have sufficient expertise to do so. There is only one serious omission from this book: the treatment of endometrial cancer in young women. All other aspects of fertility preservation are included. The text is easy to read and explanations for the uninitiated are careful and thorough. The editors have achieved the almost impossible: a textbook that is as informative as it is interesting. I would recommend it to anyone who treats illnesses that can affect fertility in both men and women. Reviewer Geoffrey Lane MD FRCOG FFRSH Consultant Gynaecological Oncologist Guy’s and St Thomas’ NHS Foundation Trust, London, UK Cambridge University Press, 2011 ISBN: 9780521196956 Hardback, 536 pages, £95.00 10.1111/j.1744-4667.2011.00086.x C 2012 Royal College of Obstetricians and Gynaecologists E1

Transcript of Principles and Practice of Fertility Preservation edited by Jacques Donnez and S Samuel Kim

2012;14:E1The Obstetrician & Gynaecologist

http://onlinetog.orgBook reviews

Book review

Principles and Practice of FertilityPreservationEditors Jacques Donnez and S Samuel Kim

This textbook brings together experts involved in all aspectsof fertility preservation. The literature regarding assistedreproduction, surgery, chemotherapy and radiotherapy, as wellas non-cancer-related topics, is extensively reviewed. A widevariety of opinion is sought, mainly from Europe and NorthAmerica.

The book is divided into ten sections and starts with anexcellent three-chapter introduction to the history of assistedconception, the effects of radiotherapy and chemotherapy onreproduction and the effects of treatments for non-cancerousconditions.

Section two focuses on cancer biology, epidemiologyand treatment; section three on reproductive biologyand cryobiology, demonstrating various methods of tissuepreservation. A section discussing fertility preservationstrategies in the male follows. This includes analysis of theeffectiveness of hormonal suppression, cryopreservation andtransplantation of cryopreserved spermatozoa, spermatogoniaand testicular tissue. A chapter is also reserved for thereproductive implications of the use of donor sperm.

Medical and surgical strategies for the preservation of fertilityin the female are reviewed comprehensively in three chapters,

which include explanations of the rationale for the useof GnRH agonists with chemotherapy. Surgery for fertilitypreservation in both cervical and ovarian cancer, includingthe techniques of ovarian transposition and trachelectomy, isreviewed comprehensively. Assisted reproduction techniquessuch as embryo and oocyte cryopreservation and vitrificationare also explored in some detail.

It is unfortunate that in this otherwise outstanding publicationthe chapters concerning the preservation of female fertilitydo not include a discussion of the management of earlyendometrial cancer in young women.

Section seven of the book deals with the management ofovarian tissue and the whole ovary in terms of preservationand transplantation, while section eight discusses how folliclescan be matured in vitro.

The penultimate section deals with the future, including theuse of pluripotent stem cells and the rather fanciful, butnevertheless exciting, prospect of an artificial ovary. The authorpoints out that this is the first publication on the subject. Thefinal section deals with the all-important subject of ethical,legal and religious considerations, including the psychologicalimpact of a cancer diagnosis.

There are few areas of the book that I can criticise. Indeed, Ibelieve my review cannot do it justice: the expertise involvedis so wide-ranging that no individual reviewer would havesufficient expertise to do so. There is only one serious omissionfrom this book: the treatment of endometrial cancer in youngwomen. All other aspects of fertility preservation are included.The text is easy to read and explanations for the uninitiatedare careful and thorough. The editors have achieved the almostimpossible: a textbook that is as informative as it is interesting.I would recommend it to anyone who treats illnesses that canaffect fertility in both men and women.

Reviewer Geoffrey Lane MD FRCOG FFRSH

Consultant Gynaecological OncologistGuy’s and St Thomas’ NHS Foundation Trust, London, UK

Cambridge University Press, 2011ISBN: 9780521196956Hardback, 536 pages, £95.0010.1111/j.1744-4667.2011.00086.x

C© 2012 Royal College of Obstetricians and Gynaecologists E1